Exploring 16th-Century Art: Key Works and Artists from Northern Europe and Spain

The Matthias Grunewald Isenheim Altarpiece was created in Alsace, France between 1510-1515.

The correct answer is Albrecht Durer. While the other three artists are also famous in art history, they did not create the mentioned self-portrait in 1500 with no specific location.

The correct answer is Albrecht Durer, a renowned German painter, printmaker, and theorist of the German Renaissance. He is known for his detailed and intricate works of art, including 'Four Horsemen of the Apocalypse' created between 1497-1498.

The correct answer is Albrecht Durer, who painted the artwork 'Adam and Eve' in 1504. The other artists mentioned, Leonardo da Vinci, Vincent van Gogh, and Pablo Picasso, were all renowned artists but did not create the specific artwork mentioned in the question.

The correct answer is Albrecht Durer who painted the Four Apostles in 1526 with no specific location mentioned. The other options are famous artists known for their works in different cities.

The correct answer provides the specific details about the artist (El Greco), the title of the artwork (Burial of Count Orgaz), the year it was created (1586), and its location (Church of Santo Tome, Toledo, Spain). The incorrect answers feature famous works by other artists with distinct styles and time periods to further test the knowledge of the respondent.

Hieronymus Bosch was a Dutch/Netherlandish painter known for his intricate and fantastical artworks. 'Garden of Earthly Delights' is one of his most famous paintings.