Microcytic And Normocytic Anemia: Quiz!

30 Questions | Total Attempts: 7938

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Microcytic And Normocytic Anemia: Quiz!

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Questions and Answers
  • 1. 
    Which of the following is NOT a cause of Microcytic Anemia?
    • A. 

      Thalassemia

    • B. 

      Anaemia of chronic disease

    • C. 

      Iron Deficiency Anemia

    • D. 

      Pancytopaenia

    • E. 

      Lead Poisoning

  • 2. 
    The lab reports for a patient with low MCV show high serum ferritin and low TIBC.  What is the most likely cause for this patient's anemia?
    • A. 

      Fe deficiency

    • B. 

      Anemia secondary to inflammation

    • C. 

      Thallassemia

    • D. 

      Hemoglobinopathy

  • 3. 
    Fe is absorbed in the:
    • A. 

      Stomach

    • B. 

      Duodenum

    • C. 

      Jejunum

    • D. 

      Ileum

  • 4. 
    Where is most non-heme iron found in the body?
    • A. 

      Bound to IF

    • B. 

      Bound to transferrin

    • C. 

      Free in plasma

    • D. 

      Stored in liver

  • 5. 
    Select the following that enhances Fe absorption.
    • A. 

      Citric acid

    • B. 

      Polyphenols (tea)

    • C. 

      Phylate (bran)

    • D. 

      Calcium

    • E. 

      Ascorbic acid

  • 6. 
    What is the most important test for Fe stores?
    • A. 

      Serum iron

    • B. 

      TIBC

    • C. 

      Serum ferritin

  • 7. 
    Which of the following is not an etiology of Fe deficiency anemia?
    • A. 

      Chronic blood loss

    • B. 

      Increased requirement

    • C. 

      Infection

    • D. 

      Malabsorption

    • E. 

      Decreased intake

  • 8. 
    TIBC increases in iron deficiency anemia because:
    • A. 

      Inflammatory response to deficiency

    • B. 

      Compensation by other factors

    • C. 

      Ability to absorb increases

  • 9. 
    TIBC stands for?
  • 10. 
    Pica, a clinical presentation for Fe deficiency anemia, is:
    • A. 

      Itchiness

    • B. 

      ED

    • C. 

      Desire to eat weird things

    • D. 

      A small woodland creature

  • 11. 
    Which lab investigations would you order if you suspect Fe deficiency anemia?
    • A. 

      CBC

    • B. 

      Blood smear

    • C. 

      Serum iron

    • D. 

      Serum ferritin

    • E. 

      TIBC

  • 12. 
    How would you treat Fe deficiency anemia?
  • 13. 
    Where is beta Thalassemia most common? 
    • A. 

      West Africa

    • B. 

      Mediterranean

    • C. 

      Arabian peninsula

    • D. 

      Southeast Asia

    • E. 

      CANADA!

  • 14. 
    What is the difference between beta-thalassemia major and beta thalassemia minor?
    • A. 

      Homozygote vs. heterozygote

    • B. 

      Acute vs. chronic

    • C. 

      Legal drinking age

  • 15. 
    Heinz bodies are made of:
    • A. 

      Excess gamma chains

    • B. 

      Excess alpha chains

    • C. 

      Excess beta chains

    • D. 

      Excess ketchup

  • 16. 
    Beta Thalassemia, unlike alpha thalassemia, presents at approximately 6 months of age.
    • A. 

      True

    • B. 

      False

  • 17. 
    Which would you expect to see on a blood smear for beta Thalassemia? 
    • A. 

      Heinz bodies

    • B. 

      Multinucleated neutrophils

    • C. 

      Target cells

    • D. 

      Hypochromic microcytic cells

    • E. 

      Hyperchromic microcytic cells

  • 18. 
    What test would you do, besides history, CBC, and blood smear, to confirm Thalassemia?
  • 19. 
    What is the treatment for beta-thalassemia minor?
    • A. 

      Blood transfusions

    • B. 

      Iron chelation

    • C. 

      Bone marrow transplant

    • D. 

      None of the above

  • 20. 
    Alpha-Thalassemia is a gene deletion related to the production of the alpha-Hb protein.  What happens when one is missing all 4 genes for alpha-Th?
  • 21. 
    Decreased or stopped production of alpha-globin chains result in HbH (4 gamma chains together) and Hb Barts (4 beta chains together)
    • A. 

      True

    • B. 

      False

  • 22. 
    On a CBC for alpha-Thalassemia, you would see anemia and reticulocytosis.  You would see Heinz bodies, hypochromic microcytic cells, and occasional target cells on the blood smear.  
    • A. 

      LDH

    • B. 

      Unconjugated bilirubin

    • C. 

      Conjugated bilirubin

    • D. 

      Urine urobilinogen

    • E. 

      Urine hemosiderin

  • 23. 
    The ABCDs of Normocytic anemia are: Acute blood loss Bone marrow failure Chronic disease and __________________
  • 24. 
    Aplastic anemia can be acquired (more common) and inherited.  What are some of the ways it can be acquired?
    • A. 

      Post viral infection

    • B. 

      Pregnancy

    • C. 

      Ionizing radiation

    • D. 

      Drugs and chemicals

    • E. 

      Who knows? (idiopathic)

  • 25. 
    Aside from the gradual onset signs of anemia, what other clinical presentations would you see with aplastic anemia?
    • A. 

      Koilonychias, "spoon nails"

    • B. 

      Associated thrombocytopenia, e.g. history of bleeding from the gums

    • C. 

      Neutropenia, e.g. repeat bacterial infections

    • D. 

      Purpura

    • E. 

      Pica

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