COPD Management (KNOELL)
Assess and monitor disease
Reduce risk factors
Rule out other respiratory disease
Manage stable COPD
Manage exacerbations
Prevent and treat exacerbations
Relieve symptoms
Reverse disease progression
Smoking cessation
Reduce mortality
None of the above, FEV1 will always be >90% after SABA use.
After
Before
During
None of the above, SABAs should not be used with spirometry.
Underdiagnose
Overdiagnose
Albuterol
Formoterol
Salmeterol
Fluticasone
Two of the above
True
False
50%
70%
80%
None of the above, ICS should not be scheduled for COPD patients
3 - 4 weeks
6 weeks - 3 months
4 - 6 months
6 months - 1 year
None of the above, ICS works for all COPD patients.
True
False
Improved spirometry
Fewer exacerbations
Increased quality of life
Improved mortality
All of the above are achieved via synergistic use of ICS and B2 agonists
Poor nutrition
Multiple childhood infections
Alpha-1-antitrypsin deficiency
Long-term cigarette exposure
Indoor or outdoor air pollution
COPD patients at or >65 y.o. in severe and very severe stages ONLY
All COPD patients at or >65 y.o.
All COPD patients
All COPD patients
COPD patients at or >65 y.o. in mild and moderate stages ONLY
Education
Exercise
Medication management
Nutritional support
Psychosocial support
Muscle function in COPD
Exercise tolerance
Exertional dyspnea or fatigue
Reverse progression of disease
Activities of daily life
Hyperinflation and airflow obstruction
Increase load and decreased efficiency of respiratory muscles
Dyspnea on exertion
Increase lactate production during exercise
Decreased oxidative capacity of skeletal muscle enzymes
Hemodynamics & Hematologic characteristics
Mental state
Exercise capacity
Lung mechanics
All of the above are improved with O2 therapy
PO2 >30 mmHg
PO2 >60 mmHg
O2 saturation >60%
O2 saturation >90%
COPD patients with right ventricular hypertrophy
PO2
PO2
COPD patients with elevated hematocrit
All of the above patients need supplemental O2 therapy at home
True
False
Inhaled bronchodilators (beta-2-agonist and anticholinergics)
Systemic oral glucocorticoids (FEV1
Theophylline
Non-invasive positive pressure ventilation
Cromones and leukotriene inhibitors
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