A lot of genetic disorders can be labeled as being caused by gene mutation, where a person’s DNA undergoes different changes. The mutations can either be deletions, insertions, or base substitutions. The quiz below is designed to test your understanding of gene and gene mutations, think that you are well informed to tackle it? Why don’t you give it a shot and get to find out!
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the repressor induces the expression of inducer.
One of the genes expressed in the operon negatively regulates the repressor.
The repressor binding site overlaps the promoter site of the operon allowing it to physically block the binding of RNA polymerase.
The repressor binding site on the DNA overlaps with the translation start site.
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It activates a repressor protein.
It activates a activator protein.
It inactivates a repressor protein.
It inactivates a activator protein.
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P
P, O, Z, Y, A
I, Z, Y, A
I, P, O, Z, Y, A
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Inducer
Repressor
Activator
Promoter
Regulatory protein
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False
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False
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Phosphorylation
Demethylation
Acetylation
Polyadenylation
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Negative inducible
Negative repressible
Positive inducible
Positive repressible
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False
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Negative inducible
Negative repressible
Positive inducible
Positive repressible
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lacI+ lacP+ lacO+ lacZ– lacY+ lacA+
. lacI+ lacP+ lacOc lacZ+ lacY+ lacA+
LacI– lacP+ lacO+ lacZ– lacY+ lacA+
LacI+ lacP– lacO+ lacZ+ lacY+ lacA+
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Negative inducible
Negative repressible
Positive inducible
Positive repressible
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True
False
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Beta-galactosidase enzyme.
Allolactose
Repressor protein.
Operator
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Transcription only when tryptophan is absent
Transcription only when tryptophan is present
Constitutive attenuation of transcription
Constitutive transcription
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LacI+ lacP+ lacO+ lacZ+ lacY– lacA+
LacI+ lacP+ lacOc lacZ+ lacY+ lacA+
Lacl+ lacP+ lacO+ lacZ+ lacY+ lacA+
LacI+ lacP– lacO+ lacZ+ lacY+ lacA+
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Negative inducible
Negative repressible
Positive inducible
Positive repressible
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These are mutations that are, respectively, cis and trans acting on lac operon expression.
These are mutations that are, respectively, trans and cis acting on lac operon expression.
These will affect the expression of I only.
These will affect the expression of only Z, Y, and A.
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P
O
P and O
I, P, O
The repressor would not be bound.
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