Case - Abnormal Liver Function

11 Questions | By Roberth5 | Last updated: Mar 21, 2022 | Total Attempts: 115

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IDHD case

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1.

Which of the following are typical of metabolic syndrome?
- A.
  
  Hypouricaemia
- B.
  
  Hypercholesterolaemia
- C.
  
  Low HDL cholsterol
- D.
  
  Hypocalcaemia
- E.
  
  Raised triglycerides
- F.
  
  Raised ESR
2.

What two medical conditions are associated with obesity?
- A.
  
  Increased CVS mortality
- B.
  
  Renal failure
- C.
  
  Increased risk of gallstones
- D.
  
  Increased risk of pancreatic cancer
- E.
  
  Increased risk of osteoporosis
3.

Select the pairs of blood tests and diagnoses that are a correct match
- A.
  
  Positive AMA - autoimmune chronic active hepatitis
- B.
  
  Low caeruloplasmin - Haemochromatosis
- C.
  
  Raised transferrin saturation - Wilson's disease
- D.
  
  Positive ANCA antibodies - primary sclerosing cholangitis
- E.
  
  Raised IgM - primary biliary cirrhosis
4.

Select TWO most useful approaches when determining actual alcohol intake
- A.
  
  Ask a close contact
- B.
  
  Routine LFTs
- C.
  
  U+Es
- D.
  
  Arrange a liver biopsy looking for specific alcohol features
- E.
  
  Measure the MCV
5.

What is the best indication of NAFLD (Non alcoholic fatty liver disease) on abdominal ultrasound from the list?
- A.
  
  Abnormal focal lesions suggestive of liver cancer
- B.
  
  Bile duct dilation
- C.
  
  A bright liver
- D.
  
  An enlarged spleen
- E.
  
  Abnormal flow in the portal vein
6.

Across the range of severity of NAFLD, which one of the following is NOT a feature of NAFLD?
- A.
  
  Simple steatosis
- B.
  
  Cirrhosis
- C.
  
  Liver cancer
- D.
  
  Advanced fibrosis
- E.
  
  Bile duct obstruction
7.

Which TWO of the following general treatment stategy should be adopted for patients with advanced NAFLD?
- A.
  
  Advise to restrict fluid intake
- B.
  
  Advise to completely abstain from alcohol
- C.
  
  Advise to reduce dietary fat
- D.
  
  Advise to take as much rest as possible
- E.
  
  Advise to increase exercise levels
8.

Select TWO Circumstances under which a typical NAFLD patient may become a candidate for liver transplant?
- A.
  
  If they were to develop increasing fatigue
- B.
  
  If they were to develop resistant ascites
- C.
  
  If they were to develop an 8cm liver cell cancer
- D.
  
  If they were to develop frequent episodes of encephalopathy
- E.
  
  If they were to have a variceal bleed
9.

KNOWLEDGE - in suspected Autoimmune hepatitis, choose the correct matchings for investigations and diagnoses
- A.
  
  AMA and PBC
- B.
  
  AMA and PSC
- C.
  
  ASMA and AIH
- D.
  
  AMA and AIH
- E.
  
  IgA and Alcohol
- F.
  
  IgG and AIH
- G.
  
  IgM and PBC
- H.
  
  IgM and Alcohol
- I.
  
  IgM and AIH
- J.
  
  IgG and Alcohol
- K.
  
  IgG and PBC
- L.
  
  IgA and PBC
- M.
  
  IgA and AIH
- N.
  
  Alpha Fetoprotein in AIH
- O.
  
  Alpha Feto-protein in HCC
- P.
  
  ANCA and PSC
- Q.
  
  ANCA and PBC
- R.
  
  AIH can be caused by ANA, ASMA, Anti LKM1 antibodies, and Soluble Liver Antigen
10.

KNOWLEDGE - choose the correct statements
- A.
  
  Elevated caeruloplasmin indicates Wilson's
- B.
  
  Elevated ferritin indicates Wilson's
- C.
  
  Elevated ferritin indicates Haemochromatosis
- D.
  
  Elevated caeruloplasmin indicates Haemochromatosis
11.

KNOWLEDGE - in Viral Hepatitis...
- A.
  
  IgG means the infection has been cleared, or vaccinated against, in the past
- B.
  
  IgM indicates an acute infection
- C.
  
  Hep A and E have similar presentations
- D.
  
  Hep A and E never progress to chronic disease
- E.
  
  Anti Hepatitis B Surface antibody indicates immunity to Hep B
- F.
  
  Anti Heptatitis B e antibody indicates decreased infectivity
- G.
  
  Anti Hepatitis B c antibody indicates immunity to Hep B
- H.
  
  Anti Hepatitis B surface antibody indicates reduced infectivity
- I.
  
  Hep B can lead to chronic hepatitis, but not HCC
- J.
  
  Hep B is a risk factor for HCC
- K.
  
  Hep B can be vaccinated against
- L.
  
  Hep C can be vaccinated against
- M.
  
  In Heb B, sexual transmission is most important route
- N.
  
  In Hep C, sexual transmission is most important route
- O.
  
  In hep B, IV transmission is most important route
- P.
  
  In hep C, IV transmission is most important route
- Q.
  
  Hep D is clinically irrelevant
- R.
  
  >60% of hep C patients develop chronic disease
- S.
  
  >80% of Hep C patients develop chronic disease