Micro Viral Hemmorhagic Fevers

16 Questions | Total Attempts: 346

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Micro Viral Hemmorhagic Fevers - Quiz

Today we’ll be taking another look at our ever-growing list of medical quizzes, turning our attention to a group of illnesses including Ebola, Marburg, Lassa fever and yellow fever, all of which are examples of viral haemorrhagic fevers. What do you know of these kinds of viral illnesses?


Questions and Answers
  • 1. 
    Working as an entomologist in Thailand, you are responsible for catching Aedes aegypti female mosquitoes in a study aimed at determining the prevalence of arthropod-borne viruses (arboviruses) in local mosquito populations. Results show that 6.5 % of female Aedes aegypti mosquitoes captured carried enveloped, spherical single-stranded, positive-sense RNA viruses about 50 nm in diameter. In this instance, Aedes aegypti female mosquitoes would serve as vector for which of the following diseases?
    • A. 

      Yellow fever

    • B. 

      Dengue

    • C. 

      Ebola hemorrhagic fever

    • D. 

      Rift Valley fever

    • E. 

      Lassa fever

  • 2. 
    Where is this population of mosquitoes most likely to be found?
    • A. 

      In urban areas

    • B. 

      In rural areas

    • C. 

      In forested areas

    • D. 

      Near running streams

    • E. 

      Near lakes

  • 3. 
    A 25-year-old female Peace Corps volunteer returning from Sierra Leone, presents with fever, malaise, prostration, diarrhea, nausea and vomiting, cough, chest pain, and a sore throat. Which hemorrhagic fever virus(es) should be part of the differential?
    • A. 

      Ebola virus

    • B. 

      Crimean-Congo virus

    • C. 

      Lassa fever virus

    • D. 

      Dengue virus

    • E. 

      All of the Above

  • 4. 
    A 25-year-old female Peace Corps volunteer returning from Sierra Leone, presents with fever, malaise, prostration, diarrhea, nausea and vomiting, cough, chest pain, and a sore throat.  Confirmation of Lassa fever is established after comparing pre-immune and immune sera from the patient. How is this virus best described?
    • A. 

      Enveloped, (-) ssRNA

    • B. 

      Enveloped, (+) ssRNA

    • C. 

      Enveloped, segmented (-) ssRNA

    • D. 

      Enveloped, segmented (+) ssRNA

    • E. 

      Filamentous, enveloped, (-) ssRNA

    • F. 

      Filamentous, enveloped, (+) ssRNA

    • G. 

      Filamentous, enveloped, segmented (-) ssRNA

    • H. 

      Filamentous, enveloped, segmented (+) ssRNA

  • 5. 
    Confirmation of Lassa fever is established after comparing pre-immune and immune sera from the patient. What is the vector for this virus?
    • A. 

      Mosquito

    • B. 

      Tick

    • C. 

      Rodent

    • D. 

      Bat

    • E. 

      Dog

  • 6. 
    A 38-year-old male UN peacekeeper returning from Liberia, western Africa, presents with fever, malaise, asthenia, cough, sore throat, abdominal pain, diarrhea, nausea, and vomiting. Later in the course of the disease, the patient presents with mucosal bleeding, conjunctival injection, face edema, rales, and hypotension. The patient is treated with ribavirin administered intravenously. Pre-immune serum from the patient is negative for hemorrhagic fever viruses, but serum obtained from the patient 15 days after resolution of the illness is positive for an enveloped, segmented (-) ssRNA virus. What is the reservoir host of the virus responsible for this patient’s disease?
    • A. 

      Rats

    • B. 

      Humans

    • C. 

      Bats

    • D. 

      Ticks

    • E. 

      Mosquitoes

  • 7. 
    An 18-year-old male student returning from the Argentine pampas, where he worked in the fields while taking a break from school, presents with fever, prostration, headache, dizziness, gastrointestinal disturbances, hypotension, and bleeding from the nose and gums. Pre-immune serum from the patient is negative for hemorrhagic fever viruses, but serum obtained from the patient 15 days after resolution of the illness is positive for an enveloped, segmented (-) ssRNA virus. What is the reservoir host of the virus responsible for this patient’s disease?
    • A. 

      Ticks

    • B. 

      Humans

    • C. 

      Bats

    • D. 

      Rats

    • E. 

      Mosquitoes

  • 8. 
    An 18-year-old male student returning from the Argentine pampas, where he worked in the fields while taking a break from school, presents with fever, prostration, headache, dizziness, gastrointestinal disturbances, hypotension, and bleeding from the nose and gums. Pre-immune serum from the patient is negative for hemorrhagic fever viruses, but serum obtained from the patient 15 days after resolution of the illness is positive for an enveloped, segmented (-) ssRNA virus. What is the most important risk factor for this disease?
    • A. 

      Age

    • B. 

      Gender

    • C. 

      Working with children

    • D. 

      Working in fields

    • E. 

      Geographical location

  • 9. 
    A patient returning from Uganda presents with abrupt onset of fever, weakness, diarrhea, nausea and vomiting, and a maculopapular rash. Pre-immune serum from the patient is negative for hemorrhagic fever viruses, but serum obtained from the patient 15 days after resolution of the illness is positive for an enveloped, (-) ssRNA filamentous virus. What is the reservoir host of the virus responsible for this patient’s disease?
    • A. 

      Rats

    • B. 

      Humans

    • C. 

      Bats

    • D. 

      Ticks

    • E. 

      Mosquitoes

  • 10. 
    A 26-year-old male teacher just returning from Vietnam presents with high fever (40C or 104F), headache, retro-orbital pain, puffy eyelids and flushing of the face, malaise, myalgias, arthralgias, and deep bone pain. His blood pressure is 120/80 mmHg, pulse is 84/min, and respiratory rate is 13/min. Lab findings show that the patient is leukopenic with absolute neutropenia and has elevated levels of serum lactate dehydrogenase, AST, and ALT. What is the most likely disease of this patient?
    • A. 

      Ebola

    • B. 

      Crimean-Congo hemorrhagic fever

    • C. 

      Yellow fever

    • D. 

      Dengue fever

    • E. 

      Lassa fever

    • F. 

      Rift Valley hemorrhagic fever

  • 11. 
    What is the vector for Dengue Fever
    • A. 

      A mosquito of the Aedes genus

    • B. 

      A mosquito of the Anopheles genus

    • C. 

      A mosquito of the Culex genus

    • D. 

      A tick of the Ixodes genus

  • 12. 
    A 40-year-old female ethnologist returning from Senegal presents with high fever (40C or 104F), vomiting, epigastric pain, jaundice, oliguria, hypotension, and petechiae. Patient history reveals a sudden onset of fever, chills, malaise, headache, nausea, and vomiting lasting about three days, until the day before yesterday at which time the patient felt much better. Blood pressure is 100/60 mmHg, pulse is 76/minute, and respiratory rate is 13/minute. Lab findings show that the patient has increased serum bilirubin and liver enzyme concentrations, azotemia, albuminuria, relative neutropenia, as well as prolonged clotting and prothrombin times. What is the most likely disease of this patient?
    • A. 

      Ebola

    • B. 

      Crimean-Congo hemorrhagic fever

    • C. 

      Yellow fever

    • D. 

      Dengue fever

    • E. 

      Lassa fever

    • F. 

      Rift Valley hemorrhagic fever

  • 13. 
    What is the vector for Yellow Fever?
    • A. 

      A mosquito of the Aedes genus

    • B. 

      A mosquito of the Anopheles genus

    • C. 

      A mosquito of the Culex genus

    • D. 

      A tick of the Ixodes genus

  • 14. 
    One of the most serious manifestations of hemorrhagic fever infections is shock, which is mostly mediated by the patient’s immune response to the virus. Which of the following ranks first as a cause of vascular leakage during hemorrhagic fever infections?
    • A. 

      Vasoactive mediators

    • B. 

      Interferons

    • C. 

      Defensins

    • D. 

      Corticosteroids

  • 15. 
    Which molecule ranks first as a cause of vascular leakage during hemorrhagic fever infections?
    • A. 

      IL-12

    • B. 

      IFN-a

    • C. 

      TGF-B

    • D. 

      IL-4

    • E. 

      TNF-a

  • 16. 
    In general, what are the cells responsible for the dissemination of viral hemorrhagic fever viruses?
    • A. 

      Neurons

    • B. 

      Lymphocytes

    • C. 

      Red blood cells

    • D. 

      Epithelial cells

    • E. 

      Mononuclear phagocytic cells (macrophages & dendritic cells)

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