This quiz titled 'Block 1 pt 2 Pedigree genetics Dr Larsen' assesses understanding of X-linked recessive traits and autosomal recessive inheritance through pedigree analysis. It focuses on calculating probabilities of genetic disorders in offspring, using real-world scenarios to enhance learning in genetics.
100% for a son and 50% for a daughter
100% for a son, zero for a daughter
50% for a son, zero for a daughter
50% for both sons and daughters
25% for a son and zero for a daughter
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1 in 4
1 in 2
1 in 16
1 in 3
1 in 9 (Bayes’ Formula)
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X linked recessive; 1 in 2 for a son and 1 in 4 for a daughter
Autosomal recessive; 1 in 2
Autosomal dominant; 1 in 2
Autosomal recessive; 1 in 4
Mitochondrial; 1 in 2
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75%
50%
25%
100%
Virtually zero
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Close to zero for both sons and daughters
1 in 2 for a son, close to zero for a daughter
1 in 4 for both sons and daughters
1 in 4 for a son, close to zero for a daughter
1 in 8 for a son, close to zero for a daughter
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1 in 4 for both sons and daughters
1 in 4 for a son, close to zero for a daughter
1 in 2 for a son, close to zero for a daughter
1 in 8 for a son, close to zero for a daughter
1 in 2 for both sons and daughters
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10%
20%
50%
12.5%
33%
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1 in 4
1 in 200
1 in 50
1 in 100
1 in 25
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1 in 800
1 in 75
1 in 300
1 in 50
1 in 150
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1/100
1/150
1/25
1/50
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II 1 will be a carrier and II 3 will be normal
II 1 will be normal and II 3 will be a carrier
Both II 1 and II 3 will be carriers
Both II 1 and II 3 will be normal
II 1 will be affected and II 3 will be normal
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III -1 will be a carrier and III - 2 will be normal
Both III -1 and III- 2 will be affected
Both III- 1 and III -2 will be normal
III -1 will be affected and III -2 will be a carrier
Both III -1 and III -2 will be carriers
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III -I will not be affected and III -3 will be affected
Both III - I and III- 3 will be affected
III -1 and III -3 will NOT be affected
III -1 will be affected and III -3 will not be affected
It can not be determined whether III 1 and III 3 will be affected based on the data presented
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This is an x- linked recessive disease, the mutant allele was received from the mother (II- 2), and she will be a carrier
This is an x linked recessive disease, the mutant allele was received from the father (II 1), and she will she a carrier
This is an autosomal dominant disease, the mutant allele was received from the mother (II 2), and she will be affected
This is an autosomal dominant disease, the mutant allele was received from the father (II 1), and she will be affected
This is an autosomal dominant disease, the mutant allele was not inherited from either the mother or father, and she will not be affected
1 in 2
2 in 3
1 in 16
1 in 4
1 i n 6
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1 in 2
1 in 3
1 in 9
1 in 4 (Bayes’ Formula)
1 in 6
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No sons will be affected, and all daughters will be carriers
All sons will be affected, and all daughters will be affected
All sons will be affected, and all daughters will be carriers
No sons will be affected, and all daughters will be affected all sons will be affected, and 1/2 the daughters will be carriers
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1/4
1/4 X 1/4 X 1/4
Probability of the unaffected parent being a carrier X 1/2
Pretty close to 100% because new mutations are frequent
50% if the other parent is normal
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Likely to have mutations in different genes, locus heterogeneity
Likely to have more affected sons than daughters
Obligatory carriers
Most likely homozygous normal and the disease was caused by a new mutation
Not at risk of having another child with the disease
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1/4 X 1/4 X 1/4
Pretty close to 100% because new mutations are frequent
1/4
50% if the other parent is normal
Probability of the unaffected parent being a carrier X 1/4
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1/3
1/4
2/3
1/2
Virtually 0
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25%
100%.
75%
50%
Virtually zero
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X linked dominant
X linked recessive
Autosomal dominant
Autosomal recessive
Y linked
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1/4
100%
2/3
1/2
Virtually 0
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All sons will be affected, and all daughters will be carriers
No sons will be affected, and all daughters will be affected
1/2 the sons will be affected, and all daughters will be carriers
All sons will be affected, and all daughters will be affected
1/2 the sons will be affected, and 1/2 the daughters will be carriers
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1/2
2/3
Pretty close to 100% because new mutations are frequent
1/4
Virtually zero
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Autosomal dominant
X linked recessive
X linked dominant
Y linked
Autosomal recessive
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