Alkadhi's Local Anesthetics

9 Questions | Total Attempts: 136

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Anesthetics Quizzes & Trivia

Test your knowledge of important concepts in local anesthetics


Questions and Answers
  • 1. 
    Place the following sensory modalities in the order in which they are affected by local anesthetics (first to last)1. Pressure2. Temperature3. Motor function4. Pain5. Touch
    • A. 

      1, 5, 4, 2, 3

    • B. 

      4, 5, 2, 1, 3

    • C. 

      4, 2, 5, 1, 3

    • D. 

      4, 2, 1, 5, 3

    • E. 

      3, 1, 5, 2, 4

  • 2. 
    Toxic effects of cocaine include all of the following except
    • A. 

      Tonic-clonic convulsion

    • B. 

      Severe bruxism

    • C. 

      Respiratory depression followed by stimulation

    • D. 

      Pseudohallucinations

    • E. 

      Formication

  • 3. 
    The proposed mechanism of action of local anesthetics is:
    • A. 

      Blocking K+ channels

    • B. 

      Blocking Ca++ channels

    • C. 

      Blocking release of NE

    • D. 

      Blocking the extracellular part of Na channels

    • E. 

      Blocking the intracellular part of Na channels

  • 4. 
    Which of the following is true regarding local anesthetics? 
    • A. 

      Given with a vasodilator to increase duration of action

    • B. 

      Thicker nerve fibers are more sensitive to local anesthetics than thinner ones

    • C. 

      The more negative the membrane potential, the greater the degree of Na channel block

    • D. 

      An active nerve is more sensitive to local anesthetics than a resting nerve

    • E. 

      Local anesthetics alter Na and K permeability in neurons

  • 5. 
    Which of the following is an advantage of using epinephrine with local anesthetics?
    • A. 

      Limits toxicity

    • B. 

      Increases concentration of local anesthetic by preventing its metabolism by the liver

    • C. 

      Causes tissue edema

    • D. 

      May lead to hypoxia and tissue damage

    • E. 

      Prevents hypotension

  • 6. 
    Which of the following is not an adverse effect associated with local anesthetics?
    • A. 

      Initial stimulation and then depression of CNS pathways

    • B. 

      Local necrosis from vasoconstrictor actions

    • C. 

      Blockage of muscarinic ACh receptors at high concentrations

    • D. 

      Urticarial rashes

    • E. 

      Decreased electrical excitability in myocardium

  • 7. 
    Which of the following is true with regards to local anesthetics?
    • A. 

      Procaine is faster and longer lasting than lidocaine

    • B. 

      Cocaine is good for topical anesthesia of upper respiratory tract

    • C. 

      Bupivacaine and cocaine are the only natural anesthetic products

    • D. 

      Procaine is hydrolyzed in vivo to GABA

    • E. 

      Lidocaine is very lipid soluble

  • 8. 
    All of the following are clinical uses for local anesthetics except:
    • A. 

      Antiarrhytmic

    • B. 

      Therapeutic nerve block and field block

    • C. 

      Stimulant, euphoriant

    • D. 

      Anticonvulsant in status epilepticus

    • E. 

      None of these. All of the above are clinical uses for local anesthetics

  • 9. 
    Which of the following characteristics is true for local anesthetics? 
    • A. 

      Molecule has to be lipid soluble to exert its Na channel blocking effect

    • B. 

      Some topical local anesthetics can be absorbed systemically and can cause toxicity

    • C. 

      The blocking effect of local anesthetics is gone when the molecule is in the cationic form

    • D. 

      Entry of local anesthetics in the brain results in CNS depression initially followed by CNS stimulation

    • E. 

      Cocaine also has anti-arrhythmic properties