The general anaesthesia quiz trivia! General anaesthesia is a form of anaesthesia in which a patient is rendered completely unconscious as a procedure is being carried out on him for a long time. Do you know what other types of anaesthesia exist, what sets them apart and the different types of drugs administered to a patient? In this quiz, you will refresh your understanding of some of the main facts surrounding general anaesthesia.
Irreversible
Can involve analgesia
Loss of consciousness
Involves amnesia
Increased autonomic responses
Anesthetics produce different levels or components of anesthesia at different anatomical loci
Hyperbaric condition reverses anesthesia
Anesthetics can be enantioselective and display steriochemical preference
Some lipid soluble, halogenated compounds do not have anesthetic activity
Anesthetic agents have cellular mechanisms, such as ability to hyperpolarize neurons, inhibit transmitter release, enhance inhibitory neurotransmission
Enhancement of memory
Enhancement of excitatory pathways, such as GABA or glycine
Selective depression of synaptic functions
Activation of the reticular activating system (RAS)
Analgesic effects due to release of natural opiates or possibly direct effect on the hypothalamus, cerebral cortex, and midbrain
Activation of a certain class of K+ channel
Increases the sensitivity of GABAa receptor to GABA
Inhibit excitatory current in NMDA receptor
Enhance the action of glycine on glycine receptor
All of the above
Old age (elderly)
Young age (children)
Pregnancy
Stress & anxiety
All of the above
Oral
Intravenous
Inhaled gases and volatile liquids
Intramuscular
Intrarectal
D, A, B, C
D, C, B, A
B, D, A, C
D, B, A, C
C, A, B, D
Loss of muscle tone
Intercostal muscle paralysis
Sensory Loss
Sleep
Amnesia
Loss of muscle tone
Intercostal muscle paralysis
Sensory loss
Sleep
Amnesia
Loss of muscle tone
Intercostal muscle paralysis
Sensory loss
Sleep
Amnesia
Stage 1
Stage 2
Stage 3
Stage 4
Stage 5
Neurons in medulla, normally insensitive, except at high concentrations
Higher center - increased excitatory neurotransmitters
Anesthetic stops pain transmission in spinal tract - dorsal horn, spinal cord, nociceptors
Decreased spinal reflex and decreased firing of ascending pathways
None of the above
Neurons in medulla, normally insensitive, except at high concentrations
Higher centers - increased excitatory neurotransmitters
Anesthetic stops pain transmission in spinal tract - dorsal horn, spinal cord, nociceptors
Decreased spinal reflex and decreased firing of ascending pathways
None of the above
Propofol
Thiopental
Katamine
Ether
All of the above answers are parenteral anesthetics.
Highly lipid soluble
Produces hallucinations, illusions, and vivid dreams, especially in children.
A congener of phencyclidine (PCD) which was taken off the market due to side effects
Good for patients at risk for hypotension and bronchiospasm
All of the following are characteristics of katamine
Ether
Thiopental
Katamine
Etomidate
Propofol
The alveolar concentration of the agent
The concentration of the agent in the inspired gas mixture
The solubility of the agent in the blood
Pulmonary blood flow (i.e. cardiac output)
All of the above
Rapid onset
Limited amount of inhalation anesthetics available as compared to parenteral anesthetics available
High therapeutic index
Low margin of safety, therefore one of the most dangerous class of drugs
Doesn't cross BBB
The concentration necessary to produce amnesia in 100% of the population
The concentration necessary to inhibit bacterial growth
The concentration necessary to prevent the elimination of inhalation anesthetics
The concentration necessary to prevent responding (to the scalpel) in 50% of the population
None of the above
Bronchodilation
Increases blood pressure
Widely used in the US
Liver toxicity
Depresses cardiac rhythm
Sevoflurane
Isoflurane
Thiopental
Enflurane
Desflurane
Prevent undesirable effects
Reduces amount of anesthetic needed
Increase effectiveness of anesthetic
Increases anxiety
All of the above are reasons for using adjuncts for anesthetics
Nitrous oxide
Diazepam
Succinylcholine
Desflurane
Fentanyl
Minimal side effects
Relatively inexpensive
Ideal anesthetic
Extremely insoluble in blood
Very rare drug
Isoflurane
Halothane
Thiopental
Sevoflurane
None of the above
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