Sickle Cell Disease Quiz

1.

What are two differences between sickle cell disease and sickle cell trait?
2.

Sickle cell is
- A.
  
  A contagious blood disorder
- B.
  
  A blood disorder
- C.
  
  Sickled-shaped red blood cells
- D.
  
  Sickled-shaped white blood cells
Correct Answer
C. Sickled-shaped red blood cells

Explanation
Sickle cell is a blood disorder characterized by the presence of sickled-shaped red blood cells. This means that the red blood cells are abnormally shaped, resembling a sickle or crescent moon. This abnormal shape affects the ability of the red blood cells to carry oxygen effectively, leading to various health problems such as anemia, pain, and organ damage. Sickle cell is not a contagious disorder, as it is caused by a genetic mutation.

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3.

Sickle Cell Anemia refers to
- A.
  
  Sickle cell disease
- B.
  
  Hemoglobin SS
- C.
  
  Hemoglobin SS and SC
- D.
  
  Hemoglobin SC
Correct Answer
B. Hemoglobin SS

Explanation
Sickle Cell Anemia refers to a genetic disorder where individuals have abnormal hemoglobin, specifically hemoglobin SS. This means that they have inherited two copies of the sickle cell gene, resulting in the production of abnormal hemoglobin. This abnormal hemoglobin causes red blood cells to become rigid and sickle-shaped, leading to various complications such as anemia, pain, organ damage, and increased risk of infections.

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4.

Red blood cells only become sickled-shaped when they lose their oxygen.
- A.
  
  True
- B.
  
  False
Correct Answer
A. True

Explanation
Before sickled red blood cells lose their oxygen, they look like normal red blood cells.

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5.

Sickle cell disease is most common in _______ & ________-_______, but it is also found in other ethnic and racial groups.

Correct Answer
Africans African-Americans, African African American, Africans African Americans, africans african-americans, africans african americans , African African-American

Explanation
Sickle cell disease is most common in Africans and African-Americans. It is also found in other ethnic and racial groups.

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6.

Sickle cells are
- A.
  
  Stiff and sticky
- B.
  
  Stiff and flexible
- C.
  
  Round and sticky
- D.
  
  Round and flexible
Correct Answer
A. Stiff and sticky

Explanation
Sickle cells are described as stiff and sticky because they have an abnormal shape, resembling a sickle or crescent moon, which causes them to become rigid and sticky. This abnormal shape is due to a genetic mutation in the hemoglobin protein, causing the red blood cells to become distorted and less flexible. The stiffness and stickiness of sickle cells can lead to various complications, such as blockages in blood vessels, reduced oxygen delivery to tissues, and increased risk of infections.

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7.

Sickled cells live only 20-30 days.
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
Sickled red blood cells die after only 10-20 days. The bone marrow can't make new red blood cells fast enough to replace the dying ones.

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8.

Red blood cells are made in the

Correct Answer
Bone marrow, Marrow

Explanation
Red blood cells are produced in the bone marrow, specifically in a process called hematopoiesis. The bone marrow contains stem cells that can differentiate into different types of blood cells, including red blood cells. These stem cells undergo a series of maturation stages and eventually develop into mature red blood cells. The bone marrow is responsible for continuously producing new red blood cells to replace the old and damaged ones, ensuring a constant supply of oxygen to the body's tissues. Therefore, the correct answer is bone marrow.

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9.

Blood types are determined by
- A.
  
  The presence or absence of certain antibodies
- B.
  
  The presence or absence of certain acids
- C.
  
  The presence and absence of certain antigens
- D.
  
  The presence and absence of certain proteins
Correct Answer
C. The presence and absence of certain antigens

Explanation
Blood types are determined by the presence and absence of certain antigens. Antigens are substances that can trigger an immune response in the body. The presence or absence of specific antigens on the surface of red blood cells determines the blood type. For example, individuals with type A blood have A antigens on their red blood cells, while those with type B blood have B antigens. Similarly, individuals with type AB blood have both A and B antigens, while those with type O blood have neither A nor B antigens.

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10.

Sickle cell is a contagious disease.
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
Sickle cell disease is an inherited, lifelong disease. Those with it inherited two sickle hemoglobin genes; one from each parent.

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11.

PICK ALL THAT APPLY.A sickle crisis or pain crisis can often be triggered by
- A.
  
  Dehydration
- B.
  
  Infection
- C.
  
  Relaxation
- D.
  
  Fever
- E.
  
  Stress
- F.
  
  Cold exposure
- G.
  
  Bleeding
Correct Answer(s)
A. Dehydration
B. Infection
D. Fever
E. Stress
F. Cold exposure
G. Bleeding

Explanation
A sickle crisis or pain crisis can be triggered by various factors. Dehydration can cause the sickle-shaped red blood cells to become more rigid and stick together, leading to blockages in blood vessels and pain. Infection can also trigger a sickle crisis as the body's immune response can cause inflammation and increase the risk of red blood cell sickling. Fever can worsen sickle cell symptoms by increasing metabolic demands and causing dehydration. Stress can trigger a sickle crisis due to the release of stress hormones that can increase blood viscosity. Cold exposure can cause blood vessels to constrict, leading to reduced blood flow and increased sickling. Bleeding can trigger a sickle crisis by reducing the oxygen-carrying capacity of the blood.

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12.

A ________ is a painful episode that occurs when red blood cells are unable to travel through vessels and causes clots due to the shape of the blood cells.

Correct Answer(s)
Pain crisis , Sickle crisis

Explanation
A pain crisis, also known as a sickle crisis, refers to a painful episode that occurs when red blood cells, which are sickle-shaped, are unable to travel smoothly through blood vessels. The abnormal shape of the blood cells causes them to stick together, forming clots, and leading to pain and tissue damage. This condition is commonly associated with sickle cell disease, a genetic disorder affecting the structure of hemoglobin in red blood cells. During a pain crisis, individuals may experience severe pain in various parts of the body, including the bones, joints, and abdomen.

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13.

The leading cause of death in kids with sickle cell disease is
- A.
  
  Acute Chest Syndrome
- B.
  
  Stroke
- C.
  
  Pneumonia
- D.
  
  Seizure
Correct Answer
C. Pneumonia

Explanation
Pneumonia is the leading cause of death in children with sickle cell disease. This is because sickle cell disease weakens the immune system, making children more susceptible to infections like pneumonia. Pneumonia is a serious infection that affects the lungs, causing symptoms such as fever, cough, and difficulty breathing. In children with sickle cell disease, pneumonia can quickly become life-threatening due to the already compromised health condition. Early detection and prompt treatment are crucial in preventing complications and reducing the risk of death in these children.

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14.

The leading cause of death in adults with sickle cell disease is
- A.
  
  Acute Chest Syndrome
- B.
  
  Stroke
- C.
  
  Pneumonia
- D.
  
  Seizure
Correct Answer
A. Acute Chest Syndrome

Explanation
Acute Chest Syndrome is the leading cause of death in adults with sickle cell disease. This condition is characterized by the blockage of blood vessels in the lungs, leading to chest pain, difficulty breathing, and fever. It is often triggered by infection or sickling of red blood cells. Acute Chest Syndrome can be life-threatening and requires immediate medical intervention, including oxygen therapy and antibiotics. Early recognition and prompt treatment are crucial in improving outcomes for patients with sickle cell disease.

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15.

There is no widely available cure for sickle cell disease.
- A.
  
  True
- B.
  
  False
Correct Answer
A. True

Explanation
Blood marrow and stem cell transplants may offer a cure for a small amount of people. There's no universal cure for sickle cell disease.

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Sickle Cell Disease Quiz

What are two differences between sickle cell disease and sickle cell trait?

Sickle cell is

Sickle Cell Anemia refers to

Red blood cells only become sickled-shaped when they lose their oxygen.

Sickle cell disease is most common in _______ & ________-_______, but it is also found in other ethnic and racial groups.

Sickle cells are

Sickled cells live only 20-30 days.

Red blood cells are made in the

Blood types are determined by

Sickle cell is a contagious disease.

PICK ALL THAT APPLY.A sickle crisis or pain crisis can often be triggered by

A ________ is a painful episode that occurs when red blood cells are unable to travel through vessels and causes clots due to the shape of the blood cells.

The leading cause of death in kids with sickle cell disease is

The leading cause of death in adults with sickle cell disease is

There is no widely available cure for sickle cell disease.

Sickle cell disease is most common in _ & -_, but it is also found in other ethnic and racial groups.