Sickle Cell Disease Quiz

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1. Sickle cell is a contagious disease.

Explanation

Sickle cell disease is an inherited, lifelong disease. Those with it inherited two sickle hemoglobin genes; one from each parent.

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About This Quiz
Sickle Cell Disease Quiz - Quiz

This quiz on Sickle Cell Disease explores the genetic and physiological aspects of sickle-shaped red blood cells. It covers the definition, specific conditions like Hemoglobin SS, and dispels common misconceptions. Ideal for learners interested in genetics and health sciences.

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2. Red blood cells are made in the 

Explanation

Red blood cells are produced in the bone marrow, specifically in a process called hematopoiesis. The bone marrow contains stem cells that can differentiate into different types of blood cells, including red blood cells. These stem cells undergo a series of maturation stages and eventually develop into mature red blood cells. The bone marrow is responsible for continuously producing new red blood cells to replace the old and damaged ones, ensuring a constant supply of oxygen to the body's tissues. Therefore, the correct answer is bone marrow.

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3. Sickle cells are 

Explanation

Sickle cells are described as stiff and sticky because they have an abnormal shape, resembling a sickle or crescent moon, which causes them to become rigid and sticky. This abnormal shape is due to a genetic mutation in the hemoglobin protein, causing the red blood cells to become distorted and less flexible. The stiffness and stickiness of sickle cells can lead to various complications, such as blockages in blood vessels, reduced oxygen delivery to tissues, and increased risk of infections.

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4. Sickle cell is 

Explanation

Sickle cell is a blood disorder characterized by the presence of sickled-shaped red blood cells. This means that the red blood cells are abnormally shaped, resembling a sickle or crescent moon. This abnormal shape affects the ability of the red blood cells to carry oxygen effectively, leading to various health problems such as anemia, pain, and organ damage. Sickle cell is not a contagious disorder, as it is caused by a genetic mutation.

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5. Red blood cells only become sickled-shaped when they lose their oxygen.

Explanation

Before sickled red blood cells lose their oxygen, they look like normal red blood cells.

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6. There is no widely available cure for sickle cell disease.

Explanation

Blood marrow and stem cell transplants may offer a cure for a small amount of people. There's no universal cure for sickle cell disease.

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7. Sickle Cell Anemia refers to

Explanation

Sickle Cell Anemia refers to a genetic disorder where individuals have abnormal hemoglobin, specifically hemoglobin SS. This means that they have inherited two copies of the sickle cell gene, resulting in the production of abnormal hemoglobin. This abnormal hemoglobin causes red blood cells to become rigid and sickle-shaped, leading to various complications such as anemia, pain, organ damage, and increased risk of infections.

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8. Sickled cells live only 20-30 days.

Explanation

Sickled red blood cells die after only 10-20 days. The bone marrow can't make new red blood cells fast enough to replace the dying ones.

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9. Blood types are determined by 

Explanation

Blood types are determined by the presence and absence of certain antigens. Antigens are substances that can trigger an immune response in the body. The presence or absence of specific antigens on the surface of red blood cells determines the blood type. For example, individuals with type A blood have A antigens on their red blood cells, while those with type B blood have B antigens. Similarly, individuals with type AB blood have both A and B antigens, while those with type O blood have neither A nor B antigens.

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10. The leading cause of death in adults with sickle cell disease is

Explanation

Acute Chest Syndrome is the leading cause of death in adults with sickle cell disease. This condition is characterized by the blockage of blood vessels in the lungs, leading to chest pain, difficulty breathing, and fever. It is often triggered by infection or sickling of red blood cells. Acute Chest Syndrome can be life-threatening and requires immediate medical intervention, including oxygen therapy and antibiotics. Early recognition and prompt treatment are crucial in improving outcomes for patients with sickle cell disease.

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11. The leading cause of death in kids with sickle cell disease is 

Explanation

Pneumonia is the leading cause of death in children with sickle cell disease. This is because sickle cell disease weakens the immune system, making children more susceptible to infections like pneumonia. Pneumonia is a serious infection that affects the lungs, causing symptoms such as fever, cough, and difficulty breathing. In children with sickle cell disease, pneumonia can quickly become life-threatening due to the already compromised health condition. Early detection and prompt treatment are crucial in preventing complications and reducing the risk of death in these children.

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12. PICK ALL THAT APPLY.A sickle crisis or pain crisis can often be triggered by  

Explanation

A sickle crisis or pain crisis can be triggered by various factors. Dehydration can cause the sickle-shaped red blood cells to become more rigid and stick together, leading to blockages in blood vessels and pain. Infection can also trigger a sickle crisis as the body's immune response can cause inflammation and increase the risk of red blood cell sickling. Fever can worsen sickle cell symptoms by increasing metabolic demands and causing dehydration. Stress can trigger a sickle crisis due to the release of stress hormones that can increase blood viscosity. Cold exposure can cause blood vessels to constrict, leading to reduced blood flow and increased sickling. Bleeding can trigger a sickle crisis by reducing the oxygen-carrying capacity of the blood.

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13. A ________ is a painful episode that occurs when red blood cells are unable to travel through vessels and causes clots due to the shape of the blood cells.

Explanation

A pain crisis, also known as a sickle crisis, refers to a painful episode that occurs when red blood cells, which are sickle-shaped, are unable to travel smoothly through blood vessels. The abnormal shape of the blood cells causes them to stick together, forming clots, and leading to pain and tissue damage. This condition is commonly associated with sickle cell disease, a genetic disorder affecting the structure of hemoglobin in red blood cells. During a pain crisis, individuals may experience severe pain in various parts of the body, including the bones, joints, and abdomen.

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14. Sickle cell disease is most common in _______ & ________-_______, but it is also found in other ethnic and racial groups.

Explanation

Sickle cell disease is most common in Africans and African-Americans. It is also found in other ethnic and racial groups.

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Sickle cell is a contagious disease.
Red blood cells are made in the 
Sickle cells are 
Sickle cell is 
Red blood cells only become sickled-shaped when they lose their...
There is no widely available cure for sickle cell disease.
Sickle Cell Anemia refers to
Sickled cells live only 20-30 days.
Blood types are determined by 
The leading cause of death in adults with sickle cell disease is
The leading cause of death in kids with sickle cell disease is 
PICK ALL THAT APPLY.A sickle crisis or pain crisis can often be...
A ________ is a painful episode that occurs when red blood cells are...
Sickle cell disease is most common in _______ & ________-_______,...
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