Thrombolytic Quiz: Can You Bust The Clot Safely?

1. Which of the following is an absolute contraindication to thrombolytic therapy?

Diabetes mellitus

Active internal bleeding

Hypertension controlled with medication

Recent dental work

2. Which lab value must be monitored closely during thrombolytic therapy?

Blood glucose only

PT/INR and aPTT

Hemoglobin only

Blood pressure only

3. True or False: Thrombolytics can be used as prophylaxis for patients at risk of thrombosis.

True

False

4. Which nursing intervention is most important during thrombolytic infusion?

Frequent vital signs and observation for bleeding

Keeping the patient NPO

Administering pain medication every 2 hours

Encouraging ambulation

5. True or False: Thrombolytics should be continued indefinitely after successful clot dissolution.

True

False

6. A patient has a history of severe allergic reaction to streptokinase. Which alternative thrombolytic is safest?

Another dose of streptokinase with premedication

TPA or reteplase

Warfarin

Heparin monotherapy

7. What is reperfusion injury in the context of thrombolytic therapy?

Damage to tissue from restoration of blood flow after ischemia

Permanent loss of cardiac function

Allergic response to the drug

Excessive bleeding from the infusion site

8. Which thrombolytic agent is derived from streptococcal bacteria and is antigenic?

Alteplase (tPA)

Reteplase

Streptokinase

Tenecteplase

9. A patient on thrombolytic therapy develops oozing from IV sites and gums. The nurse should monitor for which complication?

Hypercoagulability

Bleeding and hemorrhage

Allergic reaction

Myocardial infarction

10. True or False: Thrombolytics are the first-line treatment for all types of stroke.

True

False

11. A patient receiving thrombolytics develops sudden severe headache and confusion. What is the priority nursing action?

Administer acetaminophen for pain

Stop the infusion and notify the physician immediately

Continue monitoring vital signs

Increase infusion rate to hasten clot dissolution

12. What is the primary mechanism of action for tissue plasminogen activator (tPA)?

Directly inhibits thrombin formation

Converts plasminogen to plasmin, dissolving fibrin clots

Prevents platelet aggregation

Blocks vitamin K-dependent factors

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14. True or False: Aspirin is contraindicated in patients receiving thrombolytic therapy.

True

False

15. Which finding would indicate successful thrombolytic therapy in acute MI?

Increased chest pain

ST-segment elevation on ECG

Resolution of ST-segment elevation and symptom relief

Elevated troponin levels

16. What is the typical time window for administering thrombolytics in acute MI?

Within 6 hours of symptom onset

Within 12 hours of symptom onset

Within 24 hours of symptom onset

Only in the first 2 hours

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Thrombolytic Quiz: Can You Bust the Clot Safely?

1. Which of the following is an absolute contraindication to thrombolytic therapy?

2.

What first name or nickname would you like us to use?

2. Which lab value must be monitored closely during thrombolytic therapy?

3. True or False: Thrombolytics can be used as prophylaxis for patients at risk of thrombosis.

4. Which nursing intervention is most important during thrombolytic infusion?

5. True or False: Thrombolytics should be continued indefinitely after successful clot dissolution.

6. A patient has a history of severe allergic reaction to streptokinase. Which alternative thrombolytic is safest?

7. What is reperfusion injury in the context of thrombolytic therapy?

8. Which thrombolytic agent is derived from streptococcal bacteria and is antigenic?

9. A patient on thrombolytic therapy develops oozing from IV sites and gums. The nurse should monitor for which complication?

10. True or False: Thrombolytics are the first-line treatment for all types of stroke.

11. A patient receiving thrombolytics develops sudden severe headache and confusion. What is the priority nursing action?

12. What is the primary mechanism of action for tissue plasminogen activator (tPA)?

13. The nurse should obtain baseline ____ before administering thrombolytics.

14. True or False: Aspirin is contraindicated in patients receiving thrombolytic therapy.

15. Which finding would indicate successful thrombolytic therapy in acute MI?

16. What is the typical time window for administering thrombolytics in acute MI?

17. A patient receiving thrombolytics has an INR of 8. The nurse anticipates an order for ____.

18. The nurse notes petechiae and bruising on a patient receiving thrombolytics. This finding suggests ____.

19. Tenecteplase is preferred over alteplase in some protocols because it is ____.

20. Streptokinase differs from tPA primarily in that streptokinase is ____.