Tuberculosis (NCLEX) Quiz: Transmission & Treatment

1. True or False: A patient with a negative tuberculin skin test result can never develop active tuberculosis.

True

False

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3. Which diagnostic test is the gold standard for confirming TB diagnosis?

Sputum culture for Mycobacterium tuberculosis

Chest X-ray findings

Tuberculin skin test

Interferon-gamma release assay

4. True or False: Patients with latent TB infection are contagious and require respiratory isolation.

True

False

5. Multi-drug resistant TB (MDR-TB) is defined as resistance to at least which two first-line drugs?

Isoniazid and rifampicin

Pyrazinamide and ethambutol

Streptomycin and isoniazid

Rifampicin and pyrazinamide

6. A patient reports hemoptysis, night sweats, and weight loss for 3 weeks. Based on these constitutional and respiratory symptoms, what is the most likely diagnosis?

Active pulmonary tuberculosis

Chronic bronchitis

Pneumonia

Lung cancer

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8. Which patient population has the highest risk for TB reactivation after latent infection?

Patients with HIV/AIDS (CD4 count

Patients with type 2 diabetes only

Patients on short-term corticosteroids

Patients with asthma

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10. Extrapulmonary TB most commonly affects which site in immunocompromised patients?

Central nervous system (TB meningitis)

Gastrointestinal tract

Skin

Bone and joints

11. Mycobacterium tuberculosis is transmitted primarily through which route?

Airborne droplet nuclei from coughing or sneezing

Direct contact with infected blood

Ingestion of contaminated food

Insect vectors

12. Which vitamin supplementation is recommended for TB patients receiving isoniazid to prevent peripheral neuropathy?

Vitamin B6 (pyridoxine)

Vitamin C (ascorbic acid)

Vitamin D (calciferol)

Vitamin E (tocopherol)

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14. Rifampicin is a key component of TB therapy but interacts with many medications. Which class of drugs has reduced effectiveness when used concurrently with rifampicin?

Oral contraceptives

Acetaminophen

Penicillin antibiotics

Antacids

15. A nurse is caring for a patient in airborne isolation with active pulmonary TB. Which precaution is most important?

Use an N95 respirator mask when entering the room

Wear standard surgical mask and gloves

Use contact precautions only

No special precautions after 2 weeks of therapy

16. Which immune cells are primarily responsible for controlling Mycobacterium tuberculosis infection?

CD4+ T lymphocytes and macrophages

B lymphocytes and plasma cells

Neutrophils and eosinophils

NK cells and mast cells

17. A patient with latent TB infection should receive preventive therapy to reduce the risk of progression to active disease. Which medication is commonly used for this purpose?

Isoniazid monotherapy for 6-9 months

Rifampicin alone for 4 months

Pyrazinamide for 2 months

Ethambutol for 6 months

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19. Which finding on chest X-ray is most characteristic of pulmonary tuberculosis?

Cavitary lesions in the upper lobes

Diffuse infiltrates throughout both lungs

Pleural effusion only

Hilar lymphadenopathy only

20. A patient with active TB has been on isoniazid for 2 weeks and reports tingling in both feet. What complication is this likely indicating?

Peripheral neuropathy from isoniazid

Allergic reaction requiring immediate discontinuation

Tuberculosis meningitis

Hepatotoxicity

TB Quiz: Can You Stop the Transmission?

1. True or False: A patient with a negative tuberculin skin test result can never develop active tuberculosis.

2.

What first name or nickname would you like us to use?

2. Ethambutol is associated with optic neuritis, which can cause color blindness. Patients should be monitored for ______ vision changes, particularly red-green color discrimination.

3. Which diagnostic test is the gold standard for confirming TB diagnosis?

4. True or False: Patients with latent TB infection are contagious and require respiratory isolation.

5. Multi-drug resistant TB (MDR-TB) is defined as resistance to at least which two first-line drugs?

6. A patient reports hemoptysis, night sweats, and weight loss for 3 weeks. Based on these constitutional and respiratory symptoms, what is the most likely diagnosis?

7. Pyrazinamide can cause hyperuricemia and precipitate gout. This side effect occurs due to ______ of uric acid excretion.

8. Which patient population has the highest risk for TB reactivation after latent infection?

9. A standard TB treatment regimen consists of an intensive phase followed by a continuation phase. The intensive phase typically lasts ______ months.

10. Extrapulmonary TB most commonly affects which site in immunocompromised patients?

11. Mycobacterium tuberculosis is transmitted primarily through which route?

12. Which vitamin supplementation is recommended for TB patients receiving isoniazid to prevent peripheral neuropathy?

13. A sputum smear positive for acid-fast bacilli indicates the patient has ______ TB and is infectious.

14. Rifampicin is a key component of TB therapy but interacts with many medications. Which class of drugs has reduced effectiveness when used concurrently with rifampicin?

15. A nurse is caring for a patient in airborne isolation with active pulmonary TB. Which precaution is most important?

16. Which immune cells are primarily responsible for controlling Mycobacterium tuberculosis infection?

17. A patient with latent TB infection should receive preventive therapy to reduce the risk of progression to active disease. Which medication is commonly used for this purpose?

18. The Mantoux test (TST) is considered positive in a healthy person with an induration of ______ mm or greater.

19. Which finding on chest X-ray is most characteristic of pulmonary tuberculosis?

20. A patient with active TB has been on isoniazid for 2 weeks and reports tingling in both feet. What complication is this likely indicating?