HIV Drug Quiz: Can You Manage The Regimen?

1. True or False: Antiretroviral drugs can completely eradicate HIV from the body.

True

False

2. A patient misses several doses of their antiretroviral regimen. What is the primary concern?

Viral rebound and resistance development

Immediate disease progression

Permanent loss of CD4 recovery

Automatic treatment failure

3. True or False: Antiretroviral therapy should be started immediately upon HIV diagnosis regardless of CD4 count.

True

False

4. A patient reports lipodystrophy while on protease inhibitors. What should the nurse advise?

Discontinue all antiretrovirals

Discuss with provider about switching regimen; emphasize continued therapy importance

Increase dietary fat intake

Use anabolic steroids to manage fat loss

5. True or False: Undetectable viral load (U=U) means the patient cannot transmit HIV sexually.

True

False

6. Which medication interaction requires dose adjustment when combined with protease inhibitors?

Acetaminophen

Oral contraceptives

Vitamin supplements

Antacids containing aluminum

7. Which class of antiretroviral drugs inhibits reverse transcriptase by binding to the enzyme directly?

Nucleoside reverse transcriptase inhibitors (NRTIs)

Non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Protease inhibitors (PIs)

Integrase strand transfer inhibitors (INSTIs)

8. A patient on antiretroviral therapy reports adherence difficulty due to pill burden. What is the best recommendation?

Suggest skipping doses on weekends

Discuss single-tablet regimens with the provider

Recommend stopping therapy temporarily

Advise taking double doses to compensate

9. What is the primary goal of antiretroviral therapy in HIV management?

Cure the patient of HIV

Suppress viral load to undetectable levels and restore immunity

Prevent all opportunistic infections

Eliminate the need for preventive care

10. Integrase inhibitors such as dolutegravir are preferred because they have what advantage?

No food requirement and minimal drug interactions

Cure HIV completely

Do not require adherence monitoring

Eliminate the need for other antiretrovirals

11. A patient reports severe nausea after starting ritonavir-boosted protease inhibitor. Which action is appropriate?

Take with food and antacids; contact provider if unrelieved

Stop the medication immediately

Switch to a different drug class without provider approval

Double the dose to reach therapeutic levels faster

12. Which antiretroviral regimen component is most commonly used as a backbone in first-line therapy?

Two NRTIs plus an NNRTI or PI

Three PIs

Integrase inhibitor monotherapy

Entry inhibitor alone

13. Protease inhibitors work by blocking which viral enzyme?

Integrase

Protease

Reverse transcriptase

Attachment protein

14. A patient taking efavirenz reports dizziness and vivid dreams at night. What is the best nursing intervention?

Discontinue the medication immediately

Advise taking it in the morning instead of evening

Reassure that these side effects typically resolve in 2-4 weeks

Switch to a different NNRTI without consulting the provider

15. Which antiretroviral class is contraindicated in patients with severe renal impairment?

Integrase inhibitors

Non-nucleoside reverse transcriptase inhibitors

Nucleoside reverse transcriptase inhibitors

Entry inhibitors

16. Which side effect is most commonly associated with nucleoside reverse transcriptase inhibitors (NRTIs)?

Severe hepatotoxicity

Mitochondrial toxicity and lactic acidosis

Hyperglycemia only

Bone marrow suppression

17. A patient develops a rash while on efavirenz. What is the appropriate nursing action?

Continue the drug; mild rash usually resolves

Stop immediately and report to provider for evaluation

Apply topical corticosteroid and continue

Switch to a different drug class independently

18. A patient's CD4 count is 180 cells/μL. Which opportunistic infection prophylaxis is indicated?

Trimethoprim-sulfamethoxazole for PCP

Azithromycin for MAC

Both A and B

No prophylaxis needed

19. Entry inhibitors such as maraviroc work by blocking what viral process?

Viral attachment to CD4 receptors

Reverse transcription

Integration into host DNA

Viral protein synthesis

20. Which laboratory value must be monitored regularly in patients on antiretroviral therapy?

Viral load and CD4 count

Liver and kidney function

Lipid panel

All of the above

HIV Drug Quiz: Can You Manage the Regimen?

1. True or False: Antiretroviral drugs can completely eradicate HIV from the body.

2.

What first name or nickname would you like us to use?

2. A patient misses several doses of their antiretroviral regimen. What is the primary concern?

3. True or False: Antiretroviral therapy should be started immediately upon HIV diagnosis regardless of CD4 count.

4. A patient reports lipodystrophy while on protease inhibitors. What should the nurse advise?

5. True or False: Undetectable viral load (U=U) means the patient cannot transmit HIV sexually.

6. Which medication interaction requires dose adjustment when combined with protease inhibitors?

7. Which class of antiretroviral drugs inhibits reverse transcriptase by binding to the enzyme directly?

8. A patient on antiretroviral therapy reports adherence difficulty due to pill burden. What is the best recommendation?

9. What is the primary goal of antiretroviral therapy in HIV management?

10. Integrase inhibitors such as dolutegravir are preferred because they have what advantage?

11. A patient reports severe nausea after starting ritonavir-boosted protease inhibitor. Which action is appropriate?

12. Which antiretroviral regimen component is most commonly used as a backbone in first-line therapy?

13. Protease inhibitors work by blocking which viral enzyme?

14. A patient taking efavirenz reports dizziness and vivid dreams at night. What is the best nursing intervention?

15. Which antiretroviral class is contraindicated in patients with severe renal impairment?

16. Which side effect is most commonly associated with nucleoside reverse transcriptase inhibitors (NRTIs)?

17. A patient develops a rash while on efavirenz. What is the appropriate nursing action?

18. A patient's CD4 count is 180 cells/μL. Which opportunistic infection prophylaxis is indicated?

19. Entry inhibitors such as maraviroc work by blocking what viral process?

20. Which laboratory value must be monitored regularly in patients on antiretroviral therapy?