Digoxin Toxicity & Cardiac Glycosides NCLEX Quiz

1. Digoxin decreases heart rate through which mechanism?

Increased sympathetic stimulation

Enhanced parasympathetic (vagal) activity

Direct myocardial depression

Coronary vasodilation

2. Which statement best describes digoxin's dual action in heart failure?

Only increases heart rate and contractility

Increases contractility and decreases AV conduction

Dilates coronary arteries and reduces afterload

Blocks catecholamine release only

3. True or False: Digoxin is the first-line agent for acute heart failure in all patients.

True

False

4. A patient on digoxin should be monitored for which lab value before each dose?

Serum glucose

Serum potassium and renal function

Hemoglobin and hematocrit

Liver enzymes

Submit

6. Which visual symptom is pathognomonic for digoxin toxicity?

Blurred vision

Photophobia

Yellow-green or white halos around lights

Diplopia

7. Hypomagnesemia increases digoxin toxicity because it ____.

Increases Na+/K+-ATPase pump activity

Decreases digoxin protein binding

Increases cellular digoxin uptake and toxicity

Accelerates renal excretion

8. True or False: Digoxin is safe to use in patients with acute myocardial infarction.

True

False

9. Which GI symptom is a classic early sign of digoxin toxicity?

Constipation

Anorexia and nausea

Diarrhea

Abdominal distension

Submit

11. What is the primary mechanism of action of digoxin?

Inhibits Na+/K+-ATPase pump, increasing intracellular calcium

Blocks beta-adrenergic receptors in the heart

Dilates coronary arteries and increases blood flow

Reduces sympathetic nervous system activity

12. What is the antidote for severe digoxin toxicity?

Activated charcoal

Digoxin-specific antibody fragments (Digibind)

Naloxone

Vitamin K

13. True or False: Digoxin has a wide therapeutic index and toxicity is rare.

True

False

14. Digoxin is contraindicated in which condition?

Atrial fibrillation with rapid ventricular response

Wolff-Parkinson-White (WPW) syndrome

Heart failure with reduced ejection fraction

Sinus bradycardia

15. Which medication interaction increases digoxin levels by inhibiting renal clearance?

Phenytoin

Amiodarone

Rifampin

Phenobarbital

16. Digoxin toxicity can cause which cardiac arrhythmia?

Atrial fibrillation only

Premature ventricular contractions (PVCs)

Sinus tachycardia

Permanent heart block

17. A patient on digoxin reports nausea, vomiting, and yellow-green visual halos. What should the nurse do first?

Administer an antiemetic and continue the dose

Hold the next dose and notify the provider immediately

Increase fluid intake to promote renal clearance

Reduce the dose by half without provider notification

18. Which electrolyte imbalance most commonly increases digoxin toxicity risk?

Hyperkalemia

Hypokalemia

Hypernatremia

Hypercalcemia (mild)

Submit

20. Which patient population is at highest risk for digoxin toxicity?

Young, healthy adults with normal renal function

Older adults with decreased renal clearance and low body weight

Patients with hyperthyroidism

Athletes with high cardiac output

Digoxin Quiz: Can You Spot Toxicity?

1. Digoxin decreases heart rate through which mechanism?

2.

What first name or nickname would you like us to use?

2. Which statement best describes digoxin's dual action in heart failure?

3. True or False: Digoxin is the first-line agent for acute heart failure in all patients.

4. A patient on digoxin should be monitored for which lab value before each dose?

5. Digoxin is primarily eliminated through the ____.

6. Which visual symptom is pathognomonic for digoxin toxicity?

7. Hypomagnesemia increases digoxin toxicity because it ____.

8. True or False: Digoxin is safe to use in patients with acute myocardial infarction.

9. Which GI symptom is a classic early sign of digoxin toxicity?

10. A patient's digoxin level is 3.2 ng/mL. This is considered ____.

11. What is the primary mechanism of action of digoxin?

12. What is the antidote for severe digoxin toxicity?

13. True or False: Digoxin has a wide therapeutic index and toxicity is rare.

14. Digoxin is contraindicated in which condition?

15. Which medication interaction increases digoxin levels by inhibiting renal clearance?

16. Digoxin toxicity can cause which cardiac arrhythmia?

17. A patient on digoxin reports nausea, vomiting, and yellow-green visual halos. What should the nurse do first?

18. Which electrolyte imbalance most commonly increases digoxin toxicity risk?

19. The therapeutic serum level of digoxin is typically ____.

20. Which patient population is at highest risk for digoxin toxicity?