Coag Quiz: PT, INR Or APTT?

1. Which medication can cause a prolonged aPTT independent of heparin therapy?

Aspirin

Systemic lupus anticoagulant

Acetaminophen

Ibuprofen

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4. PT/INR and aPTT are both prolonged in liver disease. True or False?

True

False

5. PT/INR measures both intrinsic and common coagulation pathways. True or False?

True

False

6. A patient on enoxaparin (low-molecular-weight heparin) requires aPTT monitoring. True or False?

True

False

7. Heparin-induced thrombocytopenia (HIT) can cause both thrombosis and prolonged aPTT. True or False?

True

False

8. INR standardizes PT results across different laboratories. True or False?

True

False

9. A patient has a normal PT/INR but prolonged aPTT. What is the most likely diagnosis?

Liver disease

Vitamin K deficiency

Factor VIII deficiency (hemophilia A)

Disseminated intravascular coagulation

10. Fresh frozen plasma (FFP) is used to correct coagulation deficiencies. Which test guides FFP transfusion?

Hemoglobin and hematocrit

PT/INR and aPTT

Platelet count

Blood glucose

11. Which coagulation test measures the extrinsic pathway and is used to monitor warfarin therapy?

APTT

PT/INR

Thrombin time

Bleeding time

12. A patient has a PT of 22 seconds with an INR of 2.1 while on warfarin for DVT. How should you interpret this?

Subtherapeutic; increase warfarin

Therapeutic; continue current dose

Supratherapeutic; decrease warfarin

Patient needs immediate transfusion

13. What is the typical therapeutic INR range for atrial fibrillation?

1.0–2.0

2.0–3.0

3.0–4.0

4.0–5.0

14. Warfarin affects which coagulation factor first?

Factor II

Factor VII

Factor V

Factor VIII

15. A prolonged aPTT with normal PT/INR suggests a defect in which pathway?

Extrinsic pathway

Intrinsic pathway

Common pathway

Platelet adhesion

16. Which vitamin deficiency prolongs PT/INR?

Vitamin A deficiency

Vitamin B12 deficiency

Vitamin K deficiency

Vitamin C deficiency

17. Normal PT/INR range is approximately 0.8–1.1. An INR of 4.5 indicates what?

Decreased clotting risk

Increased bleeding risk

Normal coagulation

Heparin overdose

18. A patient on heparin therapy should have which test monitored closely?

PT/INR

APTT

Platelet count

Fibrinogen level

19. The activated partial thromboplastin time (aPTT) evaluates which coagulation pathway?

Extrinsic pathway only

Common pathway only

Intrinsic and common pathways

Platelet function

20. What does INR stand for in coagulation studies?

International Normalized Ratio

Intrinsic Normalized Result

International Normal Range

Intrinsic Negative Response

Coag Quiz: PT, INR or aPTT?

1. Which medication can cause a prolonged aPTT independent of heparin therapy?

2.

What first name or nickname would you like us to use?

2. Warfarin inhibits vitamin K-dependent factors; the ______ reflects this effect clinically.

3. The ______ test is most sensitive for detecting deficiencies in the intrinsic pathway.

4. PT/INR and aPTT are both prolonged in liver disease. True or False?

5. PT/INR measures both intrinsic and common coagulation pathways. True or False?

6. A patient on enoxaparin (low-molecular-weight heparin) requires aPTT monitoring. True or False?

7. Heparin-induced thrombocytopenia (HIT) can cause both thrombosis and prolonged aPTT. True or False?

8. INR standardizes PT results across different laboratories. True or False?

9. A patient has a normal PT/INR but prolonged aPTT. What is the most likely diagnosis?

10. Fresh frozen plasma (FFP) is used to correct coagulation deficiencies. Which test guides FFP transfusion?

11. Which coagulation test measures the extrinsic pathway and is used to monitor warfarin therapy?

12. A patient has a PT of 22 seconds with an INR of 2.1 while on warfarin for DVT. How should you interpret this?

13. What is the typical therapeutic INR range for atrial fibrillation?

14. Warfarin affects which coagulation factor first?

15. A prolonged aPTT with normal PT/INR suggests a defect in which pathway?

16. Which vitamin deficiency prolongs PT/INR?

17. Normal PT/INR range is approximately 0.8–1.1. An INR of 4.5 indicates what?

18. A patient on heparin therapy should have which test monitored closely?

19. The activated partial thromboplastin time (aPTT) evaluates which coagulation pathway?

20. What does INR stand for in coagulation studies?