The digestive system is responsible for breaking down food into nutrients that the body can absorb and use. It consists of a long alimentary canal (gastrointestinal tract) through which food passes, and various accessory organs that assist in digestion. The anatomy (structure) of each part of this system is closely related to its physiology (function).
In essence, food is taken in, broken down both mechanically and chemically, nutrients are absorbed, and waste is eliminated. The following sections provide a detailed look at the components of the digestive system and how they work together to digest food and maintain bodily function.
Food undergoes several key processes as it travels through the digestive system. Each process is vital to converting a bite of food into absorbable molecules:
Each section of the tract has a specific role in these processes.
From the esophagus through the stomach, intestines, and rectum, the walls of the gastrointestinal tract share a common structural plan of four layers. Each layer has a distinct role in supporting digestion and absorption. The layers, listed from innermost (closest to the food in the lumen) to outermost, are:
Layer | Description | Functions |
Mucosa | Innermost layer; includes epithelium, lamina propria, and muscularis mucosae | Secretion, nutrient absorption, and protection |
Submucosa | Connective tissue with vessels, glands, and nerves | Supports mucosa, controls secretions and blood flow |
Muscularis externa | Layers of smooth muscle; in some parts skeletal muscle | Movement via peristalsis and segmentation |
Serosa | Outer covering (or adventitia in some areas) | Protection, lubrication, and anchoring organs |
The lamina propria provides support and contains MALT (mucosa-associated lymphoid tissue), important for immune defense. The muscularis propels food and helps with mixing. The serosa produces fluid to reduce friction.
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The abdominal organs are covered and supported by folds of the peritoneum:
These structures provide physical stability and house nerves and vessels.
Digestion begins in the mouth:
This arrangement enables effective mastication.
Swallowing (deglutition) occurs in three phases:
The upper esophageal sphincter has skeletal muscle, allowing voluntary control.
The stomach has distinct regions and secretory cells:
Food becomes chyme through churning and mixing with gastric juice.
The small intestine is the major site of digestion and absorption:
Peyer's patches, part of MALT, are found especially in the ileum.
These organs deliver their secretions to the duodenum.
Key roles of the large intestine:
Peristalsis and bacterial fermentation occur here.
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Digestion is controlled by:
These systems coordinate digestive phases across different organs.
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