Semester 2 Neuro, Quiz 2 - Cerebellum

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Semester 2 Neuro, Quiz 2 - Cerebellum - Quiz

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Questions and Answers
  • 1. 

    A 70-year old man with a history of hypertension went to work and had sudden onset of nausea and vomiting. He was taken to ER, where his exam was notable for slurred speech, dysmetria on finger-to-nose testing on the left side. His gait was normal. Where is the lesion?

    • A.

      Cerebellar vermis

    • B.

      Right cerebellar hemisphere

    • C.

      Left cerebellar hemisphere

    • D.

      Fastigial nucleus

    • E.

      Vestibular nuclei

    Correct Answer
    C. Left cerebellar hemisphere
    Explanation
    The patient's symptoms of slurred speech and dysmetria on the left side indicate a lesion in the left cerebellar hemisphere. The cerebellum is responsible for coordinating voluntary movements, including speech and fine motor skills. Lesions in the cerebellar hemisphere can lead to deficits on the opposite side of the body. In this case, the left cerebellar hemisphere is affected, causing symptoms on the left side such as slurred speech and dysmetria. The other options, such as the cerebellar vermis, right cerebellar hemisphere, fastigial nucleus, and vestibular nuclei, are not consistent with the patient's symptoms.

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  • 2. 

    A 45-year-old man was admitted to the hospital with a cerebellar hemorrhage. The patient exhibited an unsteady "drunk like" gait and the physician noted that he swayed while entering the examination room. Which region of the cerebellum was most likely affected by the bleed?

    • A.

      Hemispheres of the anterior lobe

    • B.

      Hemisphere of the posterior lobe

    • C.

      Interposed nuclei

    • D.

      Dentate nucleus

    • E.

      Flocculonodular lobe

    Correct Answer
    E. Flocculonodular lobe
    Explanation
    The patient's unsteady and "drunk like" gait, as well as swaying while entering the examination room, suggest dysfunction in the vestibulocerebellum, which is responsible for balance and coordination. The vestibulocerebellum is located in the flocculonodular lobe of the cerebellum. Therefore, the most likely region affected by the cerebellar hemorrhage in this case is the flocculonodular lobe.

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  • 3. 

    Dysdiadokmesia refers to which of the following?

    • A.

      Inability to perform the Tandem-Gait test

    • B.

      Inability to stand without swaying with eyes open

    • C.

      Inability to control distance, power or speed of a movement

    • D.

      Inability to control vestibulo-ocular reflexes

    • E.

      Inability to perform rapid alternating movements with the hands

    Correct Answer
    E. Inability to perform rapid alternating movements with the hands
    Explanation
    Dysdiadokokinesia refers to the inability to perform rapid alternating movements with the hands. This condition is commonly observed in neurological disorders such as cerebellar dysfunction or lesions. It is characterized by a lack of coordination and smoothness in movements, making it difficult for individuals to perform tasks that require rapid and alternating movements, such as playing a musical instrument or clapping hands.

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  • 4. 

    Concerning the circuitry between mossy fibers, climbing fibers and cells of the cerebellar cortex, which of the following pairs both provide excitatory input?

    • A.

      Mossy fibers & Purkinje cells

    • B.

      Purkinje cells & Golgi cells

    • C.

      Granule cell parallel fibers & Mossy fibers

    • D.

      Golgi cells & Climbing fibers

    • E.

      Climbing fibers & Basket cells

    Correct Answer
    C. Granule cell parallel fibers & Mossy fibers
    Explanation
    Granule cell parallel fibers and mossy fibers both provide excitatory input. The granule cell parallel fibers are axons of granule cells in the cerebellar cortex that run parallel to each other. Mossy fibers, on the other hand, are axons that originate from various brain regions and carry sensory information to the cerebellum. Both of these fiber types release excitatory neurotransmitters onto their target cells, which leads to the activation and excitation of these cells. Therefore, the correct answer is Granule cell parallel fibers & Mossy fibers.

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  • 5. 

    As a researcher studying the circuitry of the cerebellum, which of the following nuclei do you wish to lesion if you are focusing mainly on the flocculo-nodular lobe circuitry of the cerebellum?

    • A.

      Fastigial nucleus

    • B.

      Dentate nucleus

    • C.

      Clarkes nucleus

    • D.

      Spinal border cells

    • E.

      Globose nucleus

    Correct Answer
    A. Fastigial nucleus
    Explanation
    The researcher would wish to lesion the Fastigial nucleus if they are focusing mainly on the flocculo-nodular lobe circuitry of the cerebellum. This is because the Fastigial nucleus is primarily involved in the control of eye movements and balance, which are key functions of the flocculo-nodular lobe. Lesioning the Fastigial nucleus would allow the researcher to study the specific effects on these functions and understand the circuitry of the cerebellum involved in them.

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  • 6. 

    Your 27-year old patient displays ataxia when asked to walk across the examination room. You ask him to stand still with his eyes closed and note marked swaying back and forth. When he opens his eyes the swaying persists. Vibration sense is normal on all four limbs. Given the clinical picture in this case, such ataxia is likely due to damage to which of the following structures?

    • A.

      Dorsal columns

    • B.

      Cerebral peduncles

    • C.

      Posterior limb of the internal capsule

    • D.

      Ventral horns of the spinal cord

    • E.

      Cerebellum

    Correct Answer
    E. Cerebellum
    Explanation
    The patient's ataxia, characterized by marked swaying back and forth, suggests dysfunction in the cerebellum. The cerebellum plays a crucial role in coordinating movements and maintaining balance. The fact that the swaying persists even when the patient opens his eyes indicates that the problem lies within the cerebellum rather than the sensory input from the eyes. The other structures listed, such as the dorsal columns, cerebral peduncles, posterior limb of the internal capsule, and ventral horns of the spinal cord, are not typically associated with these specific symptoms.

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  • 7. 

    Efferent axons from the dentate nucleus terminate in what thalamic nucleus and travel through what peduncle?

    • A.

      Ventral anterior nucleus of the thalamus (VA) ---superior cerebellar peduncle

    • B.

      Ventral anterior nucleus of the thalamus (VA) ---middle cerebellar peduncle

    • C.

      Ventral lateral nucleus of the thalamus (VL) ---superior cerebellar peduncle

    • D.

      Ventral lateral nucleus of the thalamus (VL) ---middle cerebellar peduncle

    • E.

      Ventral posterolateral nucleus of the thalamus (VPL) ---superior cerebellar peduncle

    Correct Answer
    C. Ventral lateral nucleus of the thalamus (VL) ---superior cerebellar peduncle
    Explanation
    Efferent axons from the dentate nucleus terminate in the Ventral lateral nucleus of the thalamus (VL) and travel through the superior cerebellar peduncle.

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  • 8. 

    As a researcher studying the circuitry of the cerebellum, which of the following nuclei do you know to be the major output neuron of the cerebellar cortex?

    • A.

      Purkinje cells

    • B.

      Dentate nucleus

    • C.

      Fastigial nucleus

    • D.

      Clarke's nucleus

    • E.

      Spinal border cells

    Correct Answer
    A. Purkinje cells
    Explanation
    Purkinje cells are known to be the major output neurons of the cerebellar cortex. They receive inputs from various sources within the cerebellum and send their axons to the deep cerebellar nuclei, which then project to other parts of the brain. Purkinje cells play a crucial role in coordinating motor movements and are involved in the regulation of balance, posture, and coordination. Their distinctive morphology and connectivity make them well-suited for integrating and modulating signals within the cerebellum.

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  • 9. 

    Which of the following ascending pathways enters the cerebellum through the peduncle marked in the picture?

    • A.

      Dorsal spinocerebellar tract

    • B.

      Cuneo cerebellar tract

    • C.

      Anterior spinocerebellar tract

    • D.

      Ponto cerebellar fibers

    • E.

      Climbing fibers

    Correct Answer
    C. Anterior spinocerebellar tract
    Explanation
    The correct answer is the anterior spinocerebellar tract. This ascending pathway enters the cerebellum through the peduncle marked in the picture. The other options listed are not associated with this specific peduncle.

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  • Current Version
  • Mar 22, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Jan 24, 2012
    Quiz Created by
    BLACKMD
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