Respiratory Quiz - Module 9

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| By Jbekkercronje
J
Jbekkercronje
Community Contributor
Quizzes Created: 8 | Total Attempts: 936
Questions: 10 | Attempts: 73

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Respiratory Quiz - Module 9 - Quiz


Questions and Answers
  • 1. 

    Leukotrienes are the major mediator causing bronchoconstriction in acute asthma

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    (false) They cause allergic inflammation.

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  • 2. 

     Leukotriene inhibitors can treat all causes of inflammation

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    (false) they can be used to treat diseases with allergic inflammation

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  • 3. 

    The lipoxygenase pathway can be interfered with by leukotriene modifiers

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    The lipoxygenase pathway is a metabolic pathway involved in the production of leukotrienes, which are inflammatory mediators. Leukotriene modifiers are drugs that can interfere with this pathway by inhibiting the activity of lipoxygenase enzymes or blocking the receptors for leukotrienes. Therefore, it is true that the lipoxygenase pathway can be interfered with by leukotriene modifiers.

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  • 4. 

    Zileuton is a leukotriene receptor antagonist that blocks the action of leukotriene D4 on its receptor

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    (false) It is a FLAP inhibitor. Montelukast, zafirlukast and pranlukast are receptor antagonists.

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  • 5. 

    Singulair is the originator form of zafirlukast

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    (false) Singulair is the originator of montelukast and Accolate is the originator zafirlukast

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  • 6. 

    Montelukast can be used in children above the age of 5, in its 4mg dosage.

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    (false) 4 mg for ages 6 months to 5, 5 mg for 6 to 14, and 10 mg for > 15 years.

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  • 7. 

    Patients must avoid eating food at the same time as administering montelukast

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    There is no need for patients to avoid eating food at the same time as administering montelukast. This means that it is not necessary to separate the intake of food and montelukast.

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  • 8. 

    Leukotriene receptor antagonists are indicated for monotherapy for severe persistent asthma

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    Leukotriene receptor antagonists are not indicated for monotherapy for severe persistent asthma. They are usually used as an add-on therapy to inhaled corticosteroids for the management of asthma symptoms. Monotherapy with leukotriene receptor antagonists may be considered for mild persistent asthma, but for severe persistent asthma, a combination of medications is typically required to achieve optimal control of symptoms.

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  • 9. 

    Leukotriene receptor antagonists are indicated for add on therapy for severe persistent asthma

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    (true), especially in children below the age of 5

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  • 10. 

    Montelukast has many severe side effects

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    The statement suggests that Montelukast has many severe side effects. However, the correct answer is False, which means that Montelukast does not have many severe side effects. This implies that the statement is incorrect and Montelukast is not associated with severe side effects.

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