In a chemical change, a new substance is formed. This means that the original substance undergoes a transformation at the molecular level, resulting in the formation of one or more new substances with different properties. This can involve the breaking and forming of chemical bonds, rearrangement of atoms, or change in the chemical composition of the substance. In contrast, a physical change does not result in the formation of a new substance and only involves a change in the physical properties of the substance, such as shape, size, or state of matter.