Pharm Mt 1 Part IV

20 Questions | Total Attempts: 64

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Pharm Mt 1 Part IV

Principles of Pharm (pgs. 26-39; skipped 31-35)


Questions and Answers
  • 1. 
    What detemerines whether an agonist is strong or weak?
  • 2. 
    What is the conversion from lbs to kg?
  • 3. 
    Briefly describe the 4 categories involved int he FDA Pregnancy Risk Factor Categories.
  • 4. 
    Which of the drug monograph sections should an OD review o find info on the half life, onset of action, binding mechanism and elimination?
    • A. 

      Indications

    • B. 

      Mech of action

    • C. 

      Pharmacokinetics/dynamics

    • D. 

      Administration

  • 5. 
    The SCr is a _____ sensitive indicator of renal function than the BUN.
  • 6. 
    What category for Pregnancy Risk Factors is a contra-indication in women who are or may become pregnant?
    • A. 

      A

    • B. 

      C

    • C. 

      D

    • D. 

      X

    • E. 

      Both options C and D

  • 7. 
    Which of the following is NOT involved in the hepatobiliary excretion process?
    • A. 

      Liver

    • B. 

      Bile

    • C. 

      Gall bladder

    • D. 

      None of the above (all are involved)

  • 8. 
    Use of actual body weight in obese patients may significanly _______ CrCl.
  • 9. 
    High doses of agonists can overcome non-competitive antagonism.
    • A. 

      True

    • B. 

      False

  • 10. 
    Renal dose adjustments are not usually needed unless the CrCl is less than ____mL/min.
    • A. 

      10

    • B. 

      25

    • C. 

      50

    • D. 

      65

  • 11. 
    DNA transcription, steroid production, stimulation of red blood production are all examples of what type of event in response to drug binding to receptor sites?
    • A. 

      Activation of cellular function

    • B. 

      Inhibition of cellular function

    • C. 

      Activation of biochemical processes

    • D. 

      Opening or closing of ionic channels

  • 12. 
    The creatinine clearance of a female is what percent of a males?
    • A. 

      55%

    • B. 

      65%

    • C. 

      75%

    • D. 

      85%

  • 13. 
    How strongly a drug molecule binds to a binding site is referred to as:
    • A. 

      Binding strength

    • B. 

      Affiliation

    • C. 

      Affinity

    • D. 

      Affixation

  • 14. 
    ________ is a concept often used when comparing the effects in the same class of drugs.
    • A. 

      Irreversible antagonism

    • B. 

      Drug efficiency

    • C. 

      Drug efficacy

    • D. 

      Drug potency

  • 15. 
    Where do agonists bind?
    • A. 

      Intracellular receptors

    • B. 

      Plasma membranes

    • C. 

      Nuclear membranes

    • D. 

      All of the above

    • E. 

      More than one of the above

  • 16. 
    What drug info monograph section should an OD review in order to find info on how the drug actually works?
    • A. 

      Indications

    • B. 

      Mechanism of action

    • C. 

      Pharmakodynamics

    • D. 

      Dosage

  • 17. 
    The margin between the therapeutic dose and the lethal dose of a drug is termed _____.
    • A. 

      Therapeutic index

    • B. 

      Lethal index

    • C. 

      Margin of safety

    • D. 

      Margin of death

  • 18. 
    High doses of agnosits can overcome competitive antagonism.
    • A. 

      True

    • B. 

      False

  • 19. 
    The amount of drug required to produce 50% of the maximal response that the drug is capable of inducing is the definition for ___________.
  • 20. 
    What Pregnancy Risk Factor Category corresponds to a drug that has no animal or female studies available to determine risks.
    • A. 

      A

    • B. 

      B

    • C. 

      C

    • D. 

      D

    • E. 

      X

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