Ocular Pharm Mt 1: Anti-allergy & Decongestant Agents
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- 1.Describe Type I hypersensitivity rxns.
- 2.List the ocular findings that indicate seasonal allergic conjunctivitis
- 3.Indicate which types of allergic hypersensitiivty reactions are most common in ocular conditions.
- A.
Type I
- B.
Type II
- C.
Type III
- D.
Type IV
- E.
Type V
- 4.Which antibody mediates Type I allergic rxns?
- A.
IgA
- B.
IgB
- C.
IgM
- D.
IgE
- 5.Indidcate the reactions of the body to histamine release.
- A.
Vasodilation
- B.
Vasoconstriction
- C.
Leakage of fluid
- D.
Blockage of fluid
- E.
Tissue swelling
- 6.In Type I, the immediate allergic response starts within ___-____ after exposure and may resonve within ___-___.
- 7.In Type I, the late phase allergic response starts within ___-____ after exposure and may last for up to ____.
- 8.Indicate the s/s of Type I reactions.
- A.
Bronchoconstriction
- B.
Rhinitis
- C.
Headache
- D.
Hives
- E.
Conj hyperemia
- F.
Anaphylactic shock
- 9.Hay fever, allergic conjunctivitis, asthma, hymenoptera strings and other chemical/toxic sensitivities are:
- A.
Type I
- B.
Type III
- C.
Type IV
- 10.Type IV has a quicker onset than Type I
- A.
True
- B.
False
- 11.Seasonal allergic conjunctvitis is characterized by ____ reactions.
- A.
Type I
- B.
Type IV
- 12.What is the def of vernal conjunctivitis?
- A.
Seasonal disorder that reaches peak in warm months, occuring mostly in adolescent males
- B.
Seasonal disorder that reaches peak in cold months, occuring mostly in middle aged males
- C.
Seasonal disorder that reaches peak in warm months, occuring mostly in adolescent females
- D.
Seasonal disorder that reaches peak in cold months, occuring mostly in adolescent males
- 13.What are the characteristics of vernal conjunctivitis?
- A.
Large papillae (like cobblestones) on the upper tarsal conj
- B.
Large follicles on the upper tarsal conj
- C.
Extreme chemosis and hyperemia
- 14.Papillary hypertrophy characterized by gelatinous thickening of the superior limbus can occur in what condition?
- A.
Vernal conjunctivitis
- B.
Seasonal allergic conjunctivitis
- C.
Atopic keratoconjunctivitis
- D.
GPC
- 15.Histamine level in the tears of individuals with this condition is often significantly higher than in others
- A.
Vernal conjunctivitis
- B.
Seasonal allergic conjunctivitis
- C.
Atopic keratoconjunctivitis
- D.
GPC
- 16.Symptoms of this condition include intense itching and thick, ropy discharge. Photophobia may occur if cornea becomes involved, ptosis may occur in papillary invovlement is signfiicant
- A.
Vernal conjunctivitis
- B.
Seasonal allergic conjunctivitis
- C.
Atopic keratoconjunctivitis
- D.
GPC
- 17.This condition is caused by acquired hypersensitivity to specific antigens. There is usually a family or personal history of allergy w/ hay fever or asthma.
- A.
Vernal conjunctivitis
- B.
Seasonal allergic conjunctivitis
- C.
Atopic keratoconjunctivitis
- D.
GPC
- 18.This condition is usually characterized by patches of thickened, excoriated skin that is dry and itchy. Ocular findings include conj chemosis and hyperemia. Corneal invovlement is not common and may manifest as a classic shield ucler or pannus.
- A.
Vernal conjunctivitis
- B.
Seasonal allergic conjunctivitis
- C.
Atopic keratoconjunctivitis
- D.
GPC
- 19.This condition is usually a reaction to materials such as proteins on CLs. Also reported in indvs with methylmethacrylate ocular prostheses.
- A.
Vernal conjunctivitis
- B.
Seasonal allergic conjunctivitis
- C.
Atopic keratoconjunctivitis
- D.
GPC
- 20.Decongestants have a vasoconstricting effects. What defines them?
- A.
Adrenergic agonists
- B.
Adrenergic antagonists
- C.
Anti-cholinergics
- D.
Cholinergic stimulants
- 21.Which of the following decongestants is available by Rx only?
- A.
Phenylephrine 10%
- B.
Naphazoline 0.1%
- C.
Oxymetazoline 0.025%
- D.
Tetrahydrozoline 0.05%
- 22.Which of these decongestants has the longest duration of action?
- A.
Phenylephrine
- B.
Naphazoline
- C.
Oxymetazoline
- D.
Tetrahydrozoline
- 23.Which of these decongestants has the shortest duration of action?
- A.
Phenylephrine
- B.
Naphazoline
- C.
Oxymetazoline
- D.
Tetrahydrozoline
- 24.What drug can increase the absorption of topically applied phenylephrine?
- A.
Local anesthetics
- B.
General anesthetics
- C.
Steroids
- D.
Anti biotics
- 25.What is the pregnancy category for ocular decongestants?
- A.
A
- B.
B
- C.
C
- D.
D
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