Pharm Mt 1 Part II

25 Questions | Total Attempts: 67

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Pharm Mt 1 Part II

Principles of Pharm (Pgs. 9-18)


Questions and Answers
  • 1. 
    Describe the key factors of drug stability.
  • 2. 
    Describe the purpose for using a loading dose followed by maitenance doses.
  • 3. 
    The setting in which the drug will be used i.e. IV meds occurs in hopsitals whereas oral meds are more appropriate for outpatient use describes the "clinical situation" of a drug.
    • A. 

      True

    • B. 

      False

  • 4. 
    25-50 mg of oral metoprolol has the same minimum effective dose in the serum as 2.5-5 mg of IV metoprolol.
    • A. 

      True

    • B. 

      False

  • 5. 
    How can one determine when steady state is reached for an continuous infusion, based on analyzing a drug serum concentration graph?
    • A. 

      Drug concentration will "flat line"

    • B. 

      Drug concentration peaks and troughs will be equal

    • C. 

      Drug concentration will show steady increase

    • D. 

      More than one of the above

  • 6. 
    Blood from the mesenteric circulation (GI tract) passed through the_______ before entering other organs.
  • 7. 
    Which of the following is FALSE in regard to oral drug administration?
    • A. 

      One of the easiest routes for pts to dose themselves

    • B. 

      Should be acid-stable

    • C. 

      Should not be absorbed by the intestinal lining in order to enter bloodstream

    • D. 

      Intestinal peristalsis can affect the absorption

  • 8. 
    Sublingual drug administration uses percutaneous absorption through the mouth and gums
    • A. 

      True

    • B. 

      False

  • 9. 
    Indicate which drugs have a high first pass effect according to lecture.
    • A. 

      Metoprolol

    • B. 

      Mannitol

    • C. 

      Beta blockers

  • 10. 
    Choose ALL that apply to the formulation of drugs.
    • A. 

      Capability of the drug to pass through one or more barriers in the body

    • B. 

      Adverse effects of the drug

    • C. 

      Intended use of the drug

    • D. 

      Clinical situation

    • E. 

      Potential misuse of the drug

    • F. 

      First pass effect

    • G. 

      Drug stability

  • 11. 
    The abbreviation for sublingual administration is SL
    • A. 

      True

    • B. 

      False

  • 12. 
    Which of the following is NOT considered a topical form of drug administration?
    • A. 

      Ophthalmic

    • B. 

      Sublingual

    • C. 

      Dermatologic

    • D. 

      Nasal

    • E. 

      Otic

  • 13. 
    The administration technique which bypasses/avoids use of the ___________ for medication absorption is called Parenteral.
  • 14. 
    If the dose of a drug is 100 mg (assume 100% bioavailability) and the half life is 8 hours, how many half-lifes will it take for less than 2 mg of the drug to still be circulating the serum?
    • A. 

      4

    • B. 

      5

    • C. 

      6

    • D. 

      7

  • 15. 
    Legible, clear notice of the condition for which a drug or device is being prescribed is legally necessary when writing a Rx
    • A. 

      True

    • B. 

      False

  • 16. 
    Which of the following drugs was presented as an example for having poor drug stability when taken orally.
    • A. 

      Vigamox

    • B. 

      Dicloxacillin

    • C. 

      Insulin

    • D. 

      Catapress

  • 17. 
    Azithromycin, concentrates ________ and after several doses its half life ___________.
    • A. 

      Intracellularly; decreases

    • B. 

      Extracellularly; decreases

    • C. 

      Extracellularly; increases

    • D. 

      Intracellularly; increases

  • 18. 
    Another name for intermittent IV administration is "piggyback"
    • A. 

      True

    • B. 

      False

  • 19. 
    Which of the following is NOT an appropriate match?
    • A. 

      Aa = of each

    • B. 

      QD = once a day

    • C. 

      Supp = supplemental

    • D. 

      U.D. = as directed

    • E. 

      None of the above (they are all correct)

    • F. 

      More than one of the above is incorrect

  • 20. 
    Both continuous infusion and single doses will eventually reach a steady state after 4-5 half lives.
    • A. 

      True

    • B. 

      False

  • 21. 
    The optimum recommended dosage frequency of many drugs is often (but not always) determined to be _______ times the half life.
    • A. 

      1-2

    • B. 

      2-3

    • C. 

      3-4

    • D. 

      4-5

  • 22. 
    The half life of a drug often relates to:
    • A. 

      Duration of action

    • B. 

      Onset of action

    • C. 

      Distribution phase

    • D. 

      Therapeutic range

  • 23. 
    Check off ALL the options that are required on an Rx label.
    • A. 

      Patient address

    • B. 

      Refills

    • C. 

      Date of birth

    • D. 

      Dr's license classification

    • E. 

      Directions for use

  • 24. 
    Drugs administered ________ reach maximum serum concentration rapidly compared to drugs administered by many other routes.
  • 25. 
    Check ALL the correct matches
    • A. 

      T.I.D. = two times per day

    • B. 

      Ung = ointment

    • C. 

      Qs = one half

    • D. 

      Tab = tablet

    • E. 

      Sig = significant warnings

    • F. 

      Dr = drop(s)

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