PA school pathophysiology quiz. Relating to GI system patho
Gastric Adenocarcinoma and Iflammatory Bowel Syndrome
Crohn's Disease and Cholecystitis
Peptic Ulcer Disease and Crohn's Disease
Crohn's Disease and Chronic Ulcerative Colitis
Inflammatory Bowel Syndrom and Peptic Ulcer Disease
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CUC with transmural inflammation
Crohn's disease-cobblestone mucosa and creeping fat
Crohn's disease with rubber hose fibrosis
CUC with raw, ulcerated hemorrhagic mucosa.
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CUC
Gastric Adenocarcinoma
PUD
Crohn's Disease
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A hyperplastic polyp
Tubulovillous adenoma
Juvenile polyp
Villous adenoma
Tubular adenoma
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Rubber Hose Fibrosis
Ulcerating Hemorrhagic mucosa
Crypt Abscesses
Creeping Fat
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Tubular
Hyperplastic
Villous
Juvenile
Tubulovillous
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Tubulovillous
Villous
Hyperplastic
Tubular
Juvenile
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True
False
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Ultrasound examination
HIDA scan
MRI
Histologic examination of the tissue
Fisch's friggin' oppinion.
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Pear seed lesion
Rubber hose fibrosis
Birds Beak
Apple Core lesion
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Thick, purulent, and prone to bleeding
Shows cobblestone pattern with creeping fat.
Prone to deep fissures penetrating into the muscle wall.
Sandpaper, friable, and prone to bleeding.
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True
False
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Most GI tumors are located in the large intestine.
More than 1/3 of all GI tumors involve the rectum and can be detected by digital exam.
The small intestines are only involved in a small percentage of GI tumors.
GI tumors are never present in the rectum, only the small and large intestine.
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Cyclic Erythroadenoma
Chronic Embryonic Achalasia
Carcinoembryonic Antigen
Carcinoma Exoantigen
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Bleeding, rectal involvement, and fever.
Fever and constipation, associated with chronic exacerbations.
Nasea, heartburn, indigestion, upset stomach, diarrhea.
Diarrhea, abdominal pain, and weight loss characterized by exacerbations and remissions.
Nausea, vomitting, and fever.
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CUC
PUD
IBS
Crohn's disease
Barretts esophagus.
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IBS
CUC
GERD
Crohn's Disease
Apendicitis
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Osteoporosis, hypertension, and hyperlipidemia.
Eye lesions, rash, and chronic dermititis.
Arthritis, eye lesions, and skin lesions.
Achalasia, arthritis, and rash.
Hypertension, blepharitis, and joint pain.
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Adenocarcinomas of the sigmoid and rectum that tend to infiltrate the intestine circumfrerentially.
Tumors of the right side of the colon that tend to grow as fungating masses or ulcerated shallow-like craters.
Tumors of the small intestine that tend to infiltrate the intestine circumfrentially.
Adenocarcinomas of the right side of the colon that grow in circles that eventually intertwince to encircle the entire circumference of the lumen.
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CUC has a prevalence of 20-40/100,000 while Crohn's has a prevalence of 70-150/100,000.
CUC is 2-3 times more prevalent than Crohn's Disease.
Crohn's disease is 2-4 times more prevalent than CUC.
CUC has a prevalence of 10/100,000 while Crohn's has a prevalence of 1/100,000.
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True
False
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True
False
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Small remnants of inflammed mucosa that appear to be elevated over the base of the surrounding ulcerations known as inflammatory pseudopolyps.
Atrophy of the crypts with aggregates of lymphocytes in the base of the crypts known as crypt abscesses.
Mild inflammation of the terminal ileum that can occur in CUC known as backwash ileitis.
Colonic ulcerations that spread through the entire colon and become confluent during ulcerative colitis known as serpiginous ulcerations.
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50%, 30-35%, 20%
15%, 50%, 35%
95%, 2.5%, 2.5%
20%, 30-35%, 50%
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Tend to narrow the intestine and obstruct the passage of feces.
Lead to chronic blood loss with dark red feces leading to anemia.
Constipation produces narrow, pencil-like feces.
A positive test for occult blood in the feces predicts the presence of cancer or an adenoma in 40-50% of cases
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Signifies distant metastasis
Confined to the bowel wall and does not penetrate into the muscularis propria.
Tumor has penetrated the muscle wall and pericolic fat, but does not involve the lymph nodes.
Astler-Collier Stage C2
Extending into the muscularis propria but not penetrating through it; uninvolved nodes.
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True
False
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The narrowing of the fibrotic intestines causing stricture.
Anal involvement.
Inflammation of the serosa leading to adhesions with adjacent intestinal loops.
Shallow mucosal defects overlying lymphoid aggregates.
Cobblestone appearance interspersed between more normal appearing mucosa.
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They are due to neoplastic epithelium that show no evidence of normal differentiation.
Small remnants of inlfammed mucosa that appear to be elevated over the base of the surrounding ulcerations
Dilated glands due to the obstructed flow of mucus.
Invading aliens pushing through the lumen trying to make their way into the vasculature.
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Tend to be clinically silent.
Produce non-specific signs such as weakness and fatigue.
Chronic blood loss with melena may cause anemia.
Slool will be narrow and pencil-like
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Brain Cancer
Cancer of the mouth
Cancer of the intestines
Prostate cancer
Ovarian Cancer
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Endoscopy and liver biopsy
Colonoscopy, X-ray, and mucosal biopsy
Ultra Sound, Colonoscopy, X-ray
CT scan, Endoscopy, biopsy
X-ray, mucosal biopsy, HIDA scan.
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True
False
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Inflammation extending through the entire wall of the intestine forming patch-like designs seen in Crohn's disease.
Non-caseating granulomas within the mucosa and submucosa associated with fibrosis of the muscularis and the serosa seen in Crohn's disease.
Creeping fat on the surface of the mucosa seen in CUC.
Creeping fat on the surface of the mucosa arranged in a patch-like formation seen in Crohn's disease.
Shallow mucosal defects overlying lymphoid aggregets which suggest immune cell involvement seen in Crohn's disease.
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Peyer's Patches
Skip Lesions
Transmural inflammation
Rubber-hose fibrosis
Cobblestoning
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In 50% of cases, the disease affects both the terminal ileum and colon. In 30%, only the ileum, and in 20% of cases, limited to the colon.
In 50% of cases, the disease affects the colon only. In 30% of cases, both the colon and the terminal ileum, and in 20% of cases, limited to the terminal ileum.
In 75% of cases, the disease affects both the terminal ileum and the colon. In the remainding 25%, the disease afflicts only the colon.
In 95% of cases, the disease affects only the terminal ileum. The remainding 5% occurs in the Duodenum.
In 50% of cases, the disease affects both the duodenum and the terminal ileum. In 30%, it affects the colon and the rectum. And in 20% of cases, only the colon.
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Non-neoplastic polyps are composed of normal glandular and stromal cells. Neoplastic polyps are composed of neoplastic epithelium with no normal differentiation.
Neoplastic polyps are defined as hyperplastic or juvenile. Non-neoplastic polyps are defined as tubular, tubulovillous, and villous.
Non-neoplastic polyps are composed of neoplastic epithelium with no normal differentiation. Neoplastic polyps are composed of normal glandular and stromal cells.
Neoplastic polyps are defined as hyperplastic and jeuvenile. Furthermore they are composed of normal glandular and stromal cells.
Non-neoplastic polyps are defined as tubular, tubulovillous, and villous and are composed of normal glandular and stromal cells.
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Their incidence increases with age
Most commin in Asian populations
More common in males at a 2:1 ratio
They are often multiple
70% of large polyps are located in the rectosigmoid area
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True
False
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95%, 3%, 1.5%, 0.5%
75%, 15%, 7%, 3%
50%, 30%, 15%, 5%
85%, 60%, 40%, 5%
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Villous polyps
Mucosal plaques
Hyperplastic polyps
Ulcerations
Exophytic Protruding masses
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A diffuse disease that does not usually extend into the ileum aside from mild inflammation of the terminal ileum ("backwash ileitis")
Initially starts as rectal lesions and spreads proximally, eventually involving the entire colon.
A disease leading to the involvement of the colon which is typically segmental.
An Intestinal Inflammation of unknown etitology that most often involves the colon.
A disease typically limited to thecolonic mucosa and submucosa.
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Anal digital palpation
Endoscopy, colonoscopy, HIDA scan
Endoscory or x-ray examination with barium enima
CT scan with contrast.
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Most common type of non-neoplastic polyp.
Usally discovered accidentally during an endoscopy.
Over 95% located in the rectosigmoid area.
Appear as small, dew-drop like protrusions on the mucosa measuring less than 5mm in diameter.
Histologically, composed of hyperplastic glands rich in goblet cells and mucin.
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Penetrating through the muscularis propria; uninvolved lymph nodes.
Penetrating through the muscularis propria; involved lymph nodes
Extending into the muscularis propria, but not penetrating through it; uninvolved lymph nodes.
Extending into the muscularis propria, but not penetrating through it; involved lymph nodes.
Tumore confined ot the mucosa
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True
False
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Invasive carcinoma is found in over 50% of these tumors.
Because of their size and broad base, these tumors cannot be resected through and endoscope.
On gross examination, they have a velvety appearance.
Malignant disease is found in 20-35% of these tumors.
Most measure more than 2 cm. in diameter.
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Colonoscopy and biopsy
Clinical, radiographic, and pathologic evaluation.
Endoscopy and HIDA scan
Biopsy only
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