Pain Medication: How Much You Know? Quiz

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Pain Medication: How Much You Know? Quiz - Quiz

Pain medication: how much you know quiz. Pain Medications are given to patients to help ease their pain either from an injury, disorder or surgery. These medications come in different types, and most of them are not off the counter. There are two main types of OTC pain medicines which are acetaminophen and nonsteroidal anti-inflammatory drugs. In this quiz, you will get to learn more about different types of drugs and see if you know as much as you think.


Questions and Answers
  • 1. 

    These block inflammation.

    • A.

      NSAIDs

    • B.

      Steroids

    • C.

      Acetaminophen

    Correct Answer(s)
    A. NSAIDs
    B. Steroids
    Explanation
    NSAIDs (nonsteroidal anti-inflammatory drugs) and steroids are both known to block inflammation. NSAIDs work by reducing the production of prostaglandins, which are substances that cause inflammation, pain, and fever. Steroids, on the other hand, suppress the immune system and reduce inflammation by inhibiting the production of certain chemicals that trigger an inflammatory response. Acetaminophen, although commonly used as a pain reliever, does not have significant anti-inflammatory properties and does not directly block inflammation.

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  • 2. 

    Steroids are:

    • A.

      Weak but specific

    • B.

      Potent and specific

    • C.

      Potent but nonspecific

    • D.

      Potent but free of side effects

    Correct Answer
    C. Potent but nonspecific
    Explanation
    Steroids are described as potent but nonspecific because they have strong effects on the body but do not specifically target one particular area or function. They can affect multiple systems and processes in the body, leading to a wide range of potential side effects. This makes them powerful medications but also increases the risk of adverse reactions.

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  • 3. 

    Opioids act in

    • A.

      The spinal cord and brain

    • B.

      The brain only

    • C.

      The spinal cord only

    • D.

      The spinal cord and site of stimulation

    Correct Answer
    A. The spinal cord and brain
    Explanation
    Opioids act in both the spinal cord and brain. The spinal cord is responsible for transmitting pain signals to the brain, and opioids can inhibit this transmission by binding to opioid receptors in the spinal cord. Additionally, opioids can also act in the brain by binding to opioid receptors located in various regions involved in pain processing and modulation. By acting in both the spinal cord and brain, opioids can effectively reduce pain perception and provide analgesic effects.

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  • 4. 

    Steroids block the formation of arachidonic acid.

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    Steroids are known to inhibit the formation of arachidonic acid. Arachidonic acid is a precursor molecule that plays a crucial role in the production of various inflammatory mediators, such as prostaglandins and leukotrienes. By blocking the formation of arachidonic acid, steroids effectively reduce the production of these inflammatory molecules, leading to their anti-inflammatory effects. Therefore, the statement "Steroids block the formation of arachidonic acid" is true.

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  • 5. 

    Prostanoids lead to formation of

    • A.

      Prostaglandin

    • B.

      Leukotrienes

    • C.

      Thromboxane

    • D.

      Cox 1 and 2

    Correct Answer(s)
    A. Prostaglandin
    C. Thromboxane
    Explanation
    Prostanoids are a group of bioactive lipid compounds that include prostaglandins and thromboxanes. Prostaglandins are formed from arachidonic acid and play various roles in inflammation, pain, and fever. Thromboxanes are also derived from arachidonic acid and are involved in platelet aggregation and vasoconstriction. Therefore, the correct answer is prostaglandin and thromboxane, as prostanoids can lead to the formation of both of these compounds.

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  • 6. 

    This is only present if there is inflammation.

    • A.

      Cox 1

    • B.

      Cox 2

    Correct Answer
    B. Cox 2
    Explanation
    Cox 2 is the correct answer because it is only present if there is inflammation. Cox 2 is an enzyme that is induced during inflammation and is responsible for producing prostaglandins, which are inflammatory mediators. Cox 1, on the other hand, is constitutively expressed and is involved in normal physiological functions such as maintaining the integrity of the stomach lining and regulating blood flow to the kidneys. Therefore, cox 2 is specifically associated with inflammation, making it the correct answer in this context.

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  • 7. 

    I come from willow tree bark, irreversibly inhibit cox 1, and modify cox 2 activity, but can cause GI side effects.  Who am I?

    • A.

      Tylenol

    • B.

      Advil

    • C.

      Aspirin

    • D.

      Nyquil

    Correct Answer
    C. Aspirin
    Explanation
    Aspirin is the correct answer because it is derived from willow tree bark and it irreversibly inhibits cox 1, which is an enzyme involved in the production of prostaglandins that cause pain and inflammation. Aspirin also modifies cox 2 activity, which further reduces pain and inflammation. However, aspirin can cause gastrointestinal (GI) side effects such as stomach irritation and ulcers.

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  • 8. 

    I block cox 1 and 2 both.  Who am I?

    • A.

      Tylenol

    • B.

      Advil

    • C.

      Aspirin

    • D.

      Nyquil

    • E.

      Cocaine

    Correct Answer
    B. Advil
    Explanation
    Advil is the correct answer because it is a nonsteroidal anti-inflammatory drug (NSAID) that blocks both cox 1 and 2 enzymes. Cox 1 and 2 enzymes are responsible for producing prostaglandins, which are involved in pain and inflammation. By blocking both enzymes, Advil effectively reduces pain and inflammation. Tylenol, on the other hand, is not an NSAID and does not block cox 1 and 2 enzymes. Aspirin also blocks cox 1 and 2 enzymes, but it is not included in the answer choices. Nyquil is a combination medication and does not specifically block cox 1 and 2 enzymes. Cocaine is a stimulant drug and not relevant to blocking cox 1 and 2 enzymes.

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  • 9. 

    I reduce pain via the CNS.  Who am I?

    • A.

      Tylenol

    • B.

      Aspirin

    • C.

      Nyquil

    • D.

      Advil

    • E.

      LSD

    Correct Answer
    A. Tylenol
    Explanation
    Tylenol is the correct answer because it is a commonly used over-the-counter pain reliever that works by reducing pain signals in the central nervous system (CNS). It contains the active ingredient acetaminophen, which acts on the brain and spinal cord to decrease pain perception. Other options like Aspirin, Nyquil, Advil, and LSD may have pain-relieving properties, but they do not specifically target the CNS for pain reduction.

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  • 10. 

    Why do NSAIDs cause tummy aches?

    • A.

      Blocking cox 2 blocks gastric mucosa turnover

    • B.

      Blocking cox 1 blocks gastric mucosa turnover

    • C.

      NSAIDs are acidic

    • D.

      NSAIDs are basic

    Correct Answer(s)
    B. Blocking cox 1 blocks gastric mucosa turnover
    C. NSAIDs are acidic
    Explanation
    NSAIDs (Nonsteroidal anti-inflammatory drugs) are known to cause tummy aches because they block the enzyme cyclooxygenase 1 (COX-1), which is responsible for protecting the stomach lining and promoting gastric mucosa turnover. When COX-1 is blocked, the stomach lining is not adequately protected, leading to irritation and inflammation in the stomach, resulting in tummy aches. Additionally, NSAIDs are acidic in nature, which can further contribute to stomach irritation and discomfort.

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  • 11. 

    Why is it surprising that Vioxx and Celebrex lead to stroke and cardiac problems?

    • A.

      They only block cox 2

    • B.

      They only block cox 1

    • C.

      They block cox 1 and 2 equally

    • D.

      They work via the CNS

    Correct Answer
    A. They only block cox 2
    Explanation
    It is surprising that Vioxx and Celebrex lead to stroke and cardiac problems because they only block cox 2. Cox 2 inhibitors were initially developed as a safer alternative to traditional nonsteroidal anti-inflammatory drugs (NSAIDs) because they specifically target the enzyme cox 2, which is responsible for inflammation and pain. Cox 1, on the other hand, is involved in the production of prostaglandins that protect the stomach lining and promote blood clotting. By selectively blocking cox 2, it was expected that these drugs would have fewer side effects on the cardiovascular system. However, the unexpected adverse effects on the heart and blood vessels indicate that there are other mechanisms at play, which are not yet fully understood.

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  • 12. 

    Pain can be greatly reduced by killing these receptors

    • A.

      Glutamate

    • B.

      Capsaicin

    • C.

      Garlic

    • D.

      Mustard oil

    • E.

      Kimchee

    Correct Answer(s)
    B. Capsaicin
    D. Mustard oil
    Explanation
    Capsaicin and mustard oil are known to have analgesic properties, meaning they can reduce pain. Capsaicin is the active component in chili peppers and works by desensitizing pain receptors, thus reducing the sensation of pain. Mustard oil contains allyl isothiocyanate, which also has analgesic properties and can provide pain relief. Therefore, killing the receptors that respond to capsaicin and mustard oil can greatly reduce pain. Glutamate, garlic, and kimchee do not have the same analgesic properties and are not known to reduce pain.

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  • 13. 

    I am from opium.

    • A.

      Opioid

    • B.

      Opiate

    Correct Answer
    B. Opiate
    Explanation
    The given statement "I am from opium" suggests that the person is indicating their origin or source of influence. Opium is a substance derived from the opium poppy plant, which contains various alkaloids including opioids. Opiates are a specific class of drugs that are derived directly from opium, such as morphine and codeine. Therefore, the correct answer in this context is "opiate" as it directly relates to the source mentioned in the statement.

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  • 14. 

    I act on opioid receptors, but I'm a fake.

    • A.

      Opioid

    • B.

      Opiate

    Correct Answer
    A. Opioid
    Explanation
    The correct answer is "opioid" because opioids are substances that act on opioid receptors in the brain and body. They can produce pain relief, sedation, and feelings of euphoria. However, the statement mentions that the answer is "fake," indicating that the substance being referred to may mimic the effects of opioids but is not a true opioid itself.

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  • 15. 

    Morphine acts on

    • A.

      Mu receptors

    • B.

      Kappa receptors

    • C.

      Delta receptors

    • D.

      Orphan receptors

    • E.

      Adopted receptors

    Correct Answer
    A. Mu receptors
    Explanation
    Morphine acts on mu receptors. These receptors are a type of opioid receptor found in the central and peripheral nervous systems. Activation of mu receptors by morphine leads to pain relief, sedation, and a feeling of euphoria.

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  • 16. 

    Naloxone acts by

    • A.

      Mimicking morphine

    • B.

      Activating opioid receptors

    • C.

      Blocking opioid receptors

    Correct Answer
    C. Blocking opioid receptors
    Explanation
    Naloxone acts by blocking opioid receptors. This means that it prevents opioids such as morphine from binding to and activating these receptors. By blocking the receptors, naloxone can reverse the effects of opioid overdose and help restore normal breathing and consciousness. It is commonly used as an emergency treatment for opioid overdose.

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  • 17. 

    The Gi beta-gamma couple activates potassium channels only in

    • A.

      Mu receptors

    • B.

      Kappa receptors

    • C.

      Delta receptors

    • D.

      Orphan receptors

    • E.

      Married receptors

    Correct Answer
    A. Mu receptors
    Explanation
    The Gi beta-gamma couple activates potassium channels only in mu receptors. This means that when the Gi beta-gamma couple is activated in mu receptors, it triggers the opening of potassium channels, allowing potassium ions to flow out of the cell. This process helps regulate the cell's electrical activity and can have various effects on neuronal signaling and neurotransmitter release.

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  • 18. 

    Opioid potassium channel activation occurs.

    • A.

      Postsynaptically

    • B.

      Presynaptically

    • C.

      Intrasynaptically

    Correct Answer
    A. Postsynaptically
    Explanation
    Opioid potassium channel activation occurs postsynaptically, meaning it happens after the synapse. This suggests that the activation of these channels is involved in regulating the activity of the postsynaptic neuron. Opioids are known to have analgesic effects, and the activation of potassium channels after the synapse may contribute to this by hyperpolarizing the postsynaptic neuron and reducing its excitability.

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  • 19. 

    NSAIDs and opioids can be safely combined.

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    NSAIDs (nonsteroidal anti-inflammatory drugs) and opioids can be safely combined under certain circumstances and with proper medical supervision. While both NSAIDs and opioids can be effective in managing pain, they work through different mechanisms and may have different side effects. Combining them can provide better pain relief for some individuals, especially in cases of severe pain. However, it is important to note that this combination should only be done under the guidance of a healthcare professional to minimize the risk of adverse effects and drug interactions.

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  • 20. 

    Opioids cause all of the following EXCEPT

    • A.

      Analgesia

    • B.

      Euphoria

    • C.

      Sedation

    • D.

      Nausea

    • E.

      Pupil dilation

    Correct Answer
    E. Pupil dilation
    Explanation
    Opioids cause analgesia by binding to opioid receptors in the brain and spinal cord, reducing the perception of pain. They also cause euphoria, a feeling of intense pleasure or happiness, by activating the reward pathways in the brain. Opioids can induce sedation, causing drowsiness and relaxation. Nausea is a common side effect of opioids, as they can stimulate the chemoreceptor trigger zone in the brainstem. However, opioids do not typically cause pupil dilation. In fact, opioids can cause pupillary constriction, known as miosis, due to their effects on the autonomic nervous system.

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  • 21. 

    Opioids get their anxiolytic effects by blocking.

    • A.

      Ach

    • B.

      Epi

    • C.

      NE

    • D.

      Glutamate

    Correct Answer
    C. NE
    Explanation
    NE stands for norepinephrine, which is a neurotransmitter involved in the body's stress response. Opioids can block the release or reuptake of NE, leading to a decrease in anxiety. Therefore, opioids get their anxiolytic effects by blocking NE.

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  • 22. 

    Opioid overdose can be lethal due to

    • A.

      Excessive vomiting

    • B.

      Euphoria-induced suicidality

    • C.

      Excessive cough suppression

    • D.

      Decreased respiration

    Correct Answer
    D. Decreased respiration
    Explanation
    Opioid overdose can be lethal due to decreased respiration. Opioids act on the central nervous system, specifically the brainstem, where they depress the respiratory centers. This leads to a decrease in the rate and depth of breathing, which can result in insufficient oxygen reaching the body's tissues. If left untreated, this can lead to respiratory failure and ultimately death.

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  • 23. 

    Diarrhea medications like loperamide and diphenoxylate are opioids that

    • A.

      Can cross the BBB

    • B.

      Can't cross the BBB

    Correct Answer
    B. Can't cross the BBB
    Explanation
    Diarrhea medications like loperamide and diphenoxylate are opioids that cannot cross the BBB (blood-brain barrier). The BBB is a protective barrier that prevents certain substances from entering the brain. Since these medications cannot cross the BBB, they primarily act on the gastrointestinal tract to alleviate symptoms of diarrhea.

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  • 24. 

    Opioids addicts are itchy because

    • A.

      They are dirty

    • B.

      Opioids block the action of allergy medication

    • C.

      Opioids cause histamine release

    • D.

      Everyone is allergic to opioids

    • E.

      Opioids attract bugs to bite

    Correct Answer
    C. Opioids cause histamine release
    Explanation
    Opioids cause histamine release, which can lead to itchiness in addicts. Histamine is a chemical that is released by the body during an allergic reaction, and it can cause symptoms such as itching, redness, and swelling. Opioids can trigger the release of histamine, resulting in itchiness as a side effect. This is why opioids addicts may experience itchiness as a common symptom.

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  • 25. 

    Tolerance develops for all the symptoms except

    • A.

      Dry throat

    • B.

      Miosis

    • C.

      Euphoria

    • D.

      GI agitation

    Correct Answer(s)
    B. Miosis
    D. GI agitation
    Explanation
    Tolerance develops for most symptoms of drug use over time, meaning that the body becomes less responsive to the effects of the drug. This can lead to a decrease in the intensity or duration of these symptoms. However, miosis (constriction of the pupils) and GI (gastrointestinal) agitation are exceptions to this pattern. Tolerance does not develop for these symptoms, meaning that they may continue to occur at the same intensity even with prolonged drug use.

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  • 26. 

    Opioid withdrawal can cause

    • A.

      Anxiety

    • B.

      Sadness

    • C.

      Diarrhea

    • D.

      Constipation

    • E.

      Nausea

    Correct Answer(s)
    A. Anxiety
    B. Sadness
    C. Diarrhea
    Explanation
    Opioid withdrawal can cause a range of symptoms, including anxiety, sadness, diarrhea, and nausea. These symptoms occur as a result of the body's dependence on opioids and the sudden removal of these substances. Anxiety and sadness are common emotional symptoms experienced during withdrawal, while diarrhea is a physical symptom caused by the disruption of the digestive system. These symptoms can vary in severity depending on the individual and the extent of their opioid dependence.

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  • 27. 

    Morphine is metabolized in the liver and becomes

    • A.

      Less active

    • B.

      More active

    • C.

      Both less active and more active

    • D.

      It stays the same until elimination

    Correct Answer
    C. Both less active and more active
    Explanation
    Morphine is metabolized in the liver through a process called biotransformation. During this process, morphine is converted into different metabolites, some of which are less active and some of which are more active than the original drug. This means that the effects of morphine can be both decreased and increased as it undergoes metabolism in the liver.

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  • 28. 

    Codeine is a prodrug.

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    Codeine is a prodrug because it is metabolized in the liver by an enzyme called CYP2D6 into its active form, morphine. The conversion of codeine to morphine is necessary for codeine to exert its analgesic effects. Without this metabolic conversion, codeine would have little to no analgesic activity. Therefore, codeine relies on this biotransformation to become pharmacologically active, making it a prodrug.

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  • 29. 

    CYP2D6 inhibitors like fluoxetine and paroxetine prevent metabolism of codeine and thus

    • A.

      Make codeine's effects longer lasting

    • B.

      Make codeine more active

    • C.

      Prevent codeine from becoming active

    Correct Answer
    C. Prevent codeine from becoming active
    Explanation
    CYP2D6 inhibitors like fluoxetine and paroxetine prevent the metabolism of codeine, which means that codeine cannot be converted into its active form. This leads to the prevention of codeine from becoming active and therefore reduces its effects.

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  • 30. 

    Codeine is _____ than morphine.

    • A.

      More potent

    • B.

      Less potent

    Correct Answer
    B. Less potent
    Explanation
    Codeine is less potent than morphine. Potency refers to the strength or effectiveness of a drug. In this case, codeine is considered to be less potent than morphine, meaning that it is not as strong or effective in producing its desired effects.

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  • 31. 

    I want the strongest lollipop.  It should be made of

    • A.

      Morphine

    • B.

      Codeine

    • C.

      Heroine

    • D.

      Fentanyl

    • E.

      Sufentanyl

    Correct Answer
    E. Sufentanyl
    Explanation
    Sufentanyl is the correct answer because it is an extremely potent synthetic opioid that is approximately 5 to 10 times stronger than fentanyl, which itself is already significantly stronger than morphine, codeine, and heroin. Therefore, sufentanyl would be the strongest choice for a lollipop.

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  • 32. 

    Heroine is stronger than morphine because

    • A.

      It can cross the BBB

    • B.

      It cant cross the BBB

    • C.

      It's illegal

    Correct Answer
    A. It can cross the BBB
    Explanation
    Heroine is stronger than morphine because it can cross the blood-brain barrier (BBB). The blood-brain barrier is a protective barrier that prevents certain substances from entering the brain. However, heroine has the ability to cross this barrier, allowing it to have a stronger effect on the central nervous system compared to morphine. This is why heroine is considered to be more potent and addictive than morphine.

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  • 33. 

    People like percocet because it combines

    • A.

      Codeine and acetaminophen

    • B.

      Codeine and aspirin

    • C.

      Heroine and cocaine

    • D.

      Morphine and fentanyl

    Correct Answer
    A. Codeine and acetaminophen
    Explanation
    The reason why people like Percocet is because it combines codeine and acetaminophen. Codeine is an opioid pain medication that provides relief from moderate to severe pain, while acetaminophen is a non-opioid pain reliever and fever reducer. The combination of these two ingredients in Percocet allows for more effective pain relief and increased potency compared to using either medication alone.

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  • 34. 

    Methodone has slow kinetics and thus is ideal for

    • A.

      Addiction detoxification

    • B.

      Treating overdose

    • C.

      Preventing addiction

    Correct Answer
    A. Addiction detoxification
    Explanation
    Methadone is a medication commonly used for addiction detoxification because of its slow kinetics. It is a long-acting opioid that helps to reduce withdrawal symptoms and cravings, making it easier for individuals to stop using drugs. Methadone's slow metabolism and elimination from the body allow for a steady and controlled tapering off of opioids, helping individuals overcome their addiction. Therefore, it is an ideal choice for addiction detoxification.

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  • 35. 

    Naloxone and Naltrexone are

    • A.

      Competitive antagonists

    • B.

      Non competitive antagonists

    • C.

      Selective agonists

    • D.

      Nonselective agonists

    Correct Answer
    A. Competitive antagonists
    Explanation
    Naloxone and Naltrexone are classified as competitive antagonists because they compete with the natural agonist (opioids) for binding to the same receptor sites. By binding to the opioid receptors, these drugs prevent the agonists from binding and activating the receptors, thereby blocking their effects. This competitive nature of naloxone and naltrexone distinguishes them from non-competitive antagonists, which bind irreversibly to the receptor and cause a permanent blockade. Additionally, they are not selective agonists because they do not activate the receptors themselves, but rather inhibit the agonist's action.

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  • 36. 

    Naloxone treats

    • A.

      Addiction

    • B.

      Overdose

    • C.

      Boredom

    Correct Answer
    B. Overdose
    Explanation
    Naloxone is a medication used to treat opioid overdose. It works by quickly reversing the effects of opioids and restoring normal breathing. When someone overdoses on opioids, such as heroin or prescription painkillers, their breathing can slow down or stop completely, leading to a life-threatening situation. Naloxone can be administered through injection or nasal spray and is often carried by first responders and individuals at risk of overdose. By quickly administering naloxone, it can help reverse the overdose and potentially save a person's life.

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  • 37. 

    Naltrexone treats

    • A.

      Overdose

    • B.

      Addiction

    • C.

      Boredom

    Correct Answer
    B. Addiction
    Explanation
    Naltrexone is a medication used to treat addiction. It works by blocking the effects of opioids in the brain, which helps to reduce cravings and prevent relapse in individuals who are addicted to opioids or alcohol. Naltrexone is commonly prescribed as part of a comprehensive treatment plan that includes counseling and support. It is not used to treat overdose or boredom, but specifically targets addiction by blocking the pleasurable effects of addictive substances.

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  • 38. 

    ___ can be taken orally but ____ must be given parenterally.

    • A.

      Heroine; Fentanyl

    • B.

      Naloxone; Naltrexone

    • C.

      Naltrexone; Naloxone

    • D.

      Codeine; Sufentanyl

    Correct Answer
    C. Naltrexone; Naloxone
    Explanation
    Naltrexone and naloxone are both opioid antagonists used to treat opioid overdose and addiction. However, naltrexone can be taken orally as a pill, while naloxone must be given parenterally, typically through injection or nasal spray. This is because naloxone has poor oral bioavailability, meaning it is not well absorbed when taken by mouth, and therefore needs to be administered directly into the bloodstream for rapid effect.

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  • Current Version
  • Mar 21, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Mar 02, 2009
    Quiz Created by
    Icanhasfarm
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