Pain Medications

38 Questions | Total Attempts: 43

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Pain Medications

Based on Dr. Ahern's lecture, these questions are all multiple-multiple choice.   that is, you may choose more than one correct answer.


Questions and Answers
  • 1. 
    These block inflammation
    • A. 

      NSAIDs

    • B. 

      Steroids

    • C. 

      Acetaminophen

  • 2. 
    Steroids are:
    • A. 

      Weak but specific

    • B. 

      Potent and specific

    • C. 

      Potent but nonspecific

    • D. 

      Potent but free of side effects

  • 3. 
    Opioids act in
    • A. 

      The spinal cord and brain

    • B. 

      The brain only

    • C. 

      The spinal cord only

    • D. 

      The spinal cord and site of stimulation

  • 4. 
    Steroids block the formation of arachidonic acid
    • A. 

      True

    • B. 

      False

  • 5. 
    Prostanoids lead to formation of
    • A. 

      Prostaglandin

    • B. 

      Leukotrienes

    • C. 

      Thromboxane

    • D. 

      Cox 1 and 2

  • 6. 
    This is only present if there is inflammation
    • A. 

      Cox 1

    • B. 

      Cox 2

  • 7. 
    I come from willow tree bark, irreversibly inhibit cox 1, and modify cox 2 activity, but can cause GI side effects.  Who am I?
    • A. 

      Tylenol

    • B. 

      Advil

    • C. 

      Aspirin

    • D. 

      Nyquil

  • 8. 
    I block cox 1 and 2 both.  Who am I?
    • A. 

      Tylenol

    • B. 

      Advil

    • C. 

      Aspirin

    • D. 

      Nyquil

    • E. 

      Cocaine

  • 9. 
    I reduce pain via the CNS.  Who am I?
    • A. 

      Tylenol

    • B. 

      Aspirin

    • C. 

      Nyquil

    • D. 

      Advil

    • E. 

      LSD

  • 10. 
    Why do NSAIDs cause tummy aches?
    • A. 

      Blocking cox 2 blocks gastric mucosa turnover

    • B. 

      Blocking cox 1 blocks gastric mucosa turnover

    • C. 

      NSAIDs are acidic

    • D. 

      NSAIDs are basic

  • 11. 
    Why is it surprising that Vioxx and Celebrex lead to stroke and cardiac problems?
    • A. 

      They only block cox 2

    • B. 

      They only block cox 1

    • C. 

      They block cox 1 and 2 equally

    • D. 

      They work via the CNS

  • 12. 
    Pain can be greatly reduced by killing these receptors
    • A. 

      Glutamate

    • B. 

      Capsaicin

    • C. 

      Garlic

    • D. 

      Mustard oil

    • E. 

      Kimchee

  • 13. 
    I am from opium
    • A. 

      Opioid

    • B. 

      Opiate

  • 14. 
    I act on opioid receptors, but I'm a fake
    • A. 

      Opioid

    • B. 

      Opiate

  • 15. 
    Morphine acts on
    • A. 

      Mu receptors

    • B. 

      Kappa receptors

    • C. 

      Delta receptors

    • D. 

      Orphan receptors

    • E. 

      Adopted receptors

  • 16. 
    Naloxone acts by
    • A. 

      Mimicking morphine

    • B. 

      Activating opioid receptors

    • C. 

      Blocking opioid receptors

  • 17. 
    The Gi beta-gamma couple activates potassium channels only in
    • A. 

      Mu receptors

    • B. 

      Kappa receptors

    • C. 

      Delta receptors

    • D. 

      Orphan receptors

    • E. 

      Married receptors

  • 18. 
    Opioid potassium channel activation occurs
    • A. 

      Postsynaptically

    • B. 

      Presynaptically

    • C. 

      Intrasynaptically

  • 19. 
    NSAIDs and opioids can be safely combined
    • A. 

      True

    • B. 

      False

  • 20. 
    Opioids cause all of the following EXCEPT
    • A. 

      Analgesia

    • B. 

      Euphoria

    • C. 

      Sedation

    • D. 

      Nausea

    • E. 

      Pupil dilation

  • 21. 
    Opioids get their anxiolytic effects by blocking
    • A. 

      Ach

    • B. 

      Epi

    • C. 

      NE

    • D. 

      Glutamate

  • 22. 
    Opioid overdose can be lethal due to
    • A. 

      Excessive vomiting

    • B. 

      Euphoria-induced suicidality

    • C. 

      Excessive cough suppression

    • D. 

      Decreased respiration

  • 23. 
    Diarrhea medications like loperamide and diphenoxylate are opioids that
    • A. 

      Can cross the BBB

    • B. 

      Can't cross the BBB

  • 24. 
    Opioids addicts are itchy because
    • A. 

      They are dirty

    • B. 

      Opioids block the action of allergy medication

    • C. 

      Opioids cause histamine release

    • D. 

      Everyone is allergic to opioids

    • E. 

      Opioids attract bugs to bite

  • 25. 
    Tolerance develops for all the symptoms except
    • A. 

      Dry throat

    • B. 

      Miosis

    • C. 

      Euphoria

    • D. 

      GI agitation

  • 26. 
    Opioid withdrawal can cause
    • A. 

      Anxiety

    • B. 

      Sadness

    • C. 

      Diarrhea

    • D. 

      Constipation

    • E. 

      Nausea

  • 27. 
    Morphine is metabolized in the liver and becomes
    • A. 

      Less active

    • B. 

      More active

    • C. 

      Both less active and more active

    • D. 

      It stays the same until elimination

  • 28. 
    Codeine is a prodrug
    • A. 

      True

    • B. 

      False

  • 29. 
    CYP2D6 inhibitors like fluoxetine and paroxetine prevent metabolism of codeine and thus
    • A. 

      Make codeine's effects longer lasting

    • B. 

      Make codeine more active

    • C. 

      Prevent codeine from becoming active

  • 30. 
    Codeine is _____ than morphine
    • A. 

      More potent

    • B. 

      Less potent

  • 31. 
    I want the strongest lollipop.  It should be made of
    • A. 

      Morphine

    • B. 

      Codeine

    • C. 

      Heroine

    • D. 

      Fentanyl

    • E. 

      Sufentanyl

  • 32. 
    Heroine is stronger than morphine because
    • A. 

      It can cross the BBB

    • B. 

      It cant cross the BBB

    • C. 

      It's illegal

  • 33. 
    People like percocet because it combines
    • A. 

      Codeine and acetaminophen

    • B. 

      Codeine and aspirin

    • C. 

      Heroine and cocaine

    • D. 

      Morphine and fentanyl

  • 34. 
    Methodone has slow kinetics and thus is ideal for
    • A. 

      Addiction detoxification

    • B. 

      Treating overdose

    • C. 

      Preventing addiction

  • 35. 
    Naloxone and Naltrexone are
    • A. 

      Competitive antagonists

    • B. 

      Non competitive antagonists

    • C. 

      Selective agonists

    • D. 

      Nonselective agonists

  • 36. 
    Naloxone treats
    • A. 

      Addiction

    • B. 

      Overdose

    • C. 

      Boredom

  • 37. 
    Naltrexone treats
    • A. 

      Overdose

    • B. 

      Addiction

    • C. 

      Boredom

  • 38. 
    ___ can be taken orally but ____ must be given parenterally
    • A. 

      Heroine; Fentanyl

    • B. 

      Naloxone; Naltrexone

    • C. 

      Naltrexone; Naloxone

    • D. 

      Codeine; Sufentanyl