Pain Medication: How Much You Know? Quiz
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Pain medication: how much you know quiz. Pain Medications are given to patients to help ease their pain either from an injury, disorder or surgery. These medications come in different types, and most of them are not off the counter. There are two main types of OTC pain medicines which are acetaminophen and nonsteroidal anti-inflammatory drugs. In this quiz, you will get to learn more about different types of drugs and see if you know as much as you think.
Questions and Answers
- 1.
These block inflammation.
- A.
NSAIDs
- B.
Steroids
- C.
Acetaminophen
Correct Answer(s)
A. NSAIDs
B. SteroidsExplanation
NSAIDs (nonsteroidal anti-inflammatory drugs) and steroids are both known to block inflammation. NSAIDs work by reducing the production of prostaglandins, which are substances that cause inflammation, pain, and fever. Steroids, on the other hand, suppress the immune system and reduce inflammation by inhibiting the production of certain chemicals that trigger an inflammatory response. Acetaminophen, although commonly used as a pain reliever, does not have significant anti-inflammatory properties and does not directly block inflammation.Rate this question:
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- 2.
Steroids are:
- A.
Weak but specific
- B.
Potent and specific
- C.
Potent but nonspecific
- D.
Potent but free of side effects
Correct Answer
C. Potent but nonspecificExplanation
Steroids are described as potent but nonspecific because they have strong effects on the body but do not specifically target one particular area or function. They can affect multiple systems and processes in the body, leading to a wide range of potential side effects. This makes them powerful medications but also increases the risk of adverse reactions.Rate this question:
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- 3.
Opioids act in
- A.
The spinal cord and brain
- B.
The brain only
- C.
The spinal cord only
- D.
The spinal cord and site of stimulation
Correct Answer
A. The spinal cord and brainExplanation
Opioids act in both the spinal cord and brain. The spinal cord is responsible for transmitting pain signals to the brain, and opioids can inhibit this transmission by binding to opioid receptors in the spinal cord. Additionally, opioids can also act in the brain by binding to opioid receptors located in various regions involved in pain processing and modulation. By acting in both the spinal cord and brain, opioids can effectively reduce pain perception and provide analgesic effects.Rate this question:
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- 4.
Steroids block the formation of arachidonic acid.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Steroids are known to inhibit the formation of arachidonic acid. Arachidonic acid is a precursor molecule that plays a crucial role in the production of various inflammatory mediators, such as prostaglandins and leukotrienes. By blocking the formation of arachidonic acid, steroids effectively reduce the production of these inflammatory molecules, leading to their anti-inflammatory effects. Therefore, the statement "Steroids block the formation of arachidonic acid" is true.Rate this question:
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- 5.
Prostanoids lead to formation of
- A.
Prostaglandin
- B.
Leukotrienes
- C.
Thromboxane
- D.
Cox 1 and 2
Correct Answer(s)
A. Prostaglandin
C. ThromboxaneExplanation
Prostanoids are a group of bioactive lipid compounds that include prostaglandins and thromboxanes. Prostaglandins are formed from arachidonic acid and play various roles in inflammation, pain, and fever. Thromboxanes are also derived from arachidonic acid and are involved in platelet aggregation and vasoconstriction. Therefore, the correct answer is prostaglandin and thromboxane, as prostanoids can lead to the formation of both of these compounds.Rate this question:
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- 6.
This is only present if there is inflammation.
- A.
Cox 1
- B.
Cox 2
Correct Answer
B. Cox 2Explanation
Cox 2 is the correct answer because it is only present if there is inflammation. Cox 2 is an enzyme that is induced during inflammation and is responsible for producing prostaglandins, which are inflammatory mediators. Cox 1, on the other hand, is constitutively expressed and is involved in normal physiological functions such as maintaining the integrity of the stomach lining and regulating blood flow to the kidneys. Therefore, cox 2 is specifically associated with inflammation, making it the correct answer in this context.Rate this question:
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- 7.
I come from willow tree bark, irreversibly inhibit cox 1, and modify cox 2 activity, but can cause GI side effects. Who am I?
- A.
Tylenol
- B.
Advil
- C.
Aspirin
- D.
Nyquil
Correct Answer
C. AspirinExplanation
Aspirin is the correct answer because it is derived from willow tree bark and it irreversibly inhibits cox 1, which is an enzyme involved in the production of prostaglandins that cause pain and inflammation. Aspirin also modifies cox 2 activity, which further reduces pain and inflammation. However, aspirin can cause gastrointestinal (GI) side effects such as stomach irritation and ulcers.Rate this question:
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- 8.
I block cox 1 and 2 both. Who am I?
- A.
Tylenol
- B.
Advil
- C.
Aspirin
- D.
Nyquil
- E.
Cocaine
Correct Answer
B. AdvilExplanation
Advil is the correct answer because it is a nonsteroidal anti-inflammatory drug (NSAID) that blocks both cox 1 and 2 enzymes. Cox 1 and 2 enzymes are responsible for producing prostaglandins, which are involved in pain and inflammation. By blocking both enzymes, Advil effectively reduces pain and inflammation. Tylenol, on the other hand, is not an NSAID and does not block cox 1 and 2 enzymes. Aspirin also blocks cox 1 and 2 enzymes, but it is not included in the answer choices. Nyquil is a combination medication and does not specifically block cox 1 and 2 enzymes. Cocaine is a stimulant drug and not relevant to blocking cox 1 and 2 enzymes.Rate this question:
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- 9.
I reduce pain via the CNS. Who am I?
- A.
Tylenol
- B.
Aspirin
- C.
Nyquil
- D.
Advil
- E.
LSD
Correct Answer
A. TylenolExplanation
Tylenol is the correct answer because it is a commonly used over-the-counter pain reliever that works by reducing pain signals in the central nervous system (CNS). It contains the active ingredient acetaminophen, which acts on the brain and spinal cord to decrease pain perception. Other options like Aspirin, Nyquil, Advil, and LSD may have pain-relieving properties, but they do not specifically target the CNS for pain reduction.Rate this question:
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- 10.
Why do NSAIDs cause tummy aches?
- A.
Blocking cox 2 blocks gastric mucosa turnover
- B.
Blocking cox 1 blocks gastric mucosa turnover
- C.
NSAIDs are acidic
- D.
NSAIDs are basic
Correct Answer(s)
B. Blocking cox 1 blocks gastric mucosa turnover
C. NSAIDs are acidicExplanation
NSAIDs (Nonsteroidal anti-inflammatory drugs) are known to cause tummy aches because they block the enzyme cyclooxygenase 1 (COX-1), which is responsible for protecting the stomach lining and promoting gastric mucosa turnover. When COX-1 is blocked, the stomach lining is not adequately protected, leading to irritation and inflammation in the stomach, resulting in tummy aches. Additionally, NSAIDs are acidic in nature, which can further contribute to stomach irritation and discomfort.Rate this question:
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- 11.
Why is it surprising that Vioxx and Celebrex lead to stroke and cardiac problems?
- A.
They only block cox 2
- B.
They only block cox 1
- C.
They block cox 1 and 2 equally
- D.
They work via the CNS
Correct Answer
A. They only block cox 2Explanation
It is surprising that Vioxx and Celebrex lead to stroke and cardiac problems because they only block cox 2. Cox 2 inhibitors were initially developed as a safer alternative to traditional nonsteroidal anti-inflammatory drugs (NSAIDs) because they specifically target the enzyme cox 2, which is responsible for inflammation and pain. Cox 1, on the other hand, is involved in the production of prostaglandins that protect the stomach lining and promote blood clotting. By selectively blocking cox 2, it was expected that these drugs would have fewer side effects on the cardiovascular system. However, the unexpected adverse effects on the heart and blood vessels indicate that there are other mechanisms at play, which are not yet fully understood.Rate this question:
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- 12.
Pain can be greatly reduced by killing these receptors
- A.
Glutamate
- B.
Capsaicin
- C.
Garlic
- D.
Mustard oil
- E.
Kimchee
Correct Answer(s)
B. Capsaicin
D. Mustard oilExplanation
Capsaicin and mustard oil are known to have analgesic properties, meaning they can reduce pain. Capsaicin is the active component in chili peppers and works by desensitizing pain receptors, thus reducing the sensation of pain. Mustard oil contains allyl isothiocyanate, which also has analgesic properties and can provide pain relief. Therefore, killing the receptors that respond to capsaicin and mustard oil can greatly reduce pain. Glutamate, garlic, and kimchee do not have the same analgesic properties and are not known to reduce pain.Rate this question:
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- 13.
I am from opium.
- A.
Opioid
- B.
Opiate
Correct Answer
B. OpiateExplanation
The given statement "I am from opium" suggests that the person is indicating their origin or source of influence. Opium is a substance derived from the opium poppy plant, which contains various alkaloids including opioids. Opiates are a specific class of drugs that are derived directly from opium, such as morphine and codeine. Therefore, the correct answer in this context is "opiate" as it directly relates to the source mentioned in the statement.Rate this question:
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- 14.
I act on opioid receptors, but I'm a fake.
- A.
Opioid
- B.
Opiate
Correct Answer
A. OpioidExplanation
The correct answer is "opioid" because opioids are substances that act on opioid receptors in the brain and body. They can produce pain relief, sedation, and feelings of euphoria. However, the statement mentions that the answer is "fake," indicating that the substance being referred to may mimic the effects of opioids but is not a true opioid itself.Rate this question:
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- 15.
Morphine acts on
- A.
Mu receptors
- B.
Kappa receptors
- C.
Delta receptors
- D.
Orphan receptors
- E.
Adopted receptors
Correct Answer
A. Mu receptorsExplanation
Morphine acts on mu receptors. These receptors are a type of opioid receptor found in the central and peripheral nervous systems. Activation of mu receptors by morphine leads to pain relief, sedation, and a feeling of euphoria.Rate this question:
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- 16.
Naloxone acts by
- A.
Mimicking morphine
- B.
Activating opioid receptors
- C.
Blocking opioid receptors
Correct Answer
C. Blocking opioid receptorsExplanation
Naloxone acts by blocking opioid receptors. This means that it prevents opioids such as morphine from binding to and activating these receptors. By blocking the receptors, naloxone can reverse the effects of opioid overdose and help restore normal breathing and consciousness. It is commonly used as an emergency treatment for opioid overdose.Rate this question:
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- 17.
The Gi beta-gamma couple activates potassium channels only in
- A.
Mu receptors
- B.
Kappa receptors
- C.
Delta receptors
- D.
Orphan receptors
- E.
Married receptors
Correct Answer
A. Mu receptorsExplanation
The Gi beta-gamma couple activates potassium channels only in mu receptors. This means that when the Gi beta-gamma couple is activated in mu receptors, it triggers the opening of potassium channels, allowing potassium ions to flow out of the cell. This process helps regulate the cell's electrical activity and can have various effects on neuronal signaling and neurotransmitter release.Rate this question:
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- 18.
Opioid potassium channel activation occurs.
- A.
Postsynaptically
- B.
Presynaptically
- C.
Intrasynaptically
Correct Answer
A. PostsynapticallyExplanation
Opioid potassium channel activation occurs postsynaptically, meaning it happens after the synapse. This suggests that the activation of these channels is involved in regulating the activity of the postsynaptic neuron. Opioids are known to have analgesic effects, and the activation of potassium channels after the synapse may contribute to this by hyperpolarizing the postsynaptic neuron and reducing its excitability.Rate this question:
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- 19.
NSAIDs and opioids can be safely combined.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
NSAIDs (nonsteroidal anti-inflammatory drugs) and opioids can be safely combined under certain circumstances and with proper medical supervision. While both NSAIDs and opioids can be effective in managing pain, they work through different mechanisms and may have different side effects. Combining them can provide better pain relief for some individuals, especially in cases of severe pain. However, it is important to note that this combination should only be done under the guidance of a healthcare professional to minimize the risk of adverse effects and drug interactions.Rate this question:
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- 20.
Opioids cause all of the following EXCEPT
- A.
Analgesia
- B.
Euphoria
- C.
Sedation
- D.
Nausea
- E.
Pupil dilation
Correct Answer
E. Pupil dilationExplanation
Opioids cause analgesia by binding to opioid receptors in the brain and spinal cord, reducing the perception of pain. They also cause euphoria, a feeling of intense pleasure or happiness, by activating the reward pathways in the brain. Opioids can induce sedation, causing drowsiness and relaxation. Nausea is a common side effect of opioids, as they can stimulate the chemoreceptor trigger zone in the brainstem. However, opioids do not typically cause pupil dilation. In fact, opioids can cause pupillary constriction, known as miosis, due to their effects on the autonomic nervous system.Rate this question:
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- 21.
Opioids get their anxiolytic effects by blocking.
- A.
Ach
- B.
Epi
- C.
NE
- D.
Glutamate
Correct Answer
C. NEExplanation
NE stands for norepinephrine, which is a neurotransmitter involved in the body's stress response. Opioids can block the release or reuptake of NE, leading to a decrease in anxiety. Therefore, opioids get their anxiolytic effects by blocking NE.Rate this question:
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- 22.
Opioid overdose can be lethal due to
- A.
Excessive vomiting
- B.
Euphoria-induced suicidality
- C.
Excessive cough suppression
- D.
Decreased respiration
Correct Answer
D. Decreased respirationExplanation
Opioid overdose can be lethal due to decreased respiration. Opioids act on the central nervous system, specifically the brainstem, where they depress the respiratory centers. This leads to a decrease in the rate and depth of breathing, which can result in insufficient oxygen reaching the body's tissues. If left untreated, this can lead to respiratory failure and ultimately death.Rate this question:
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- 23.
Diarrhea medications like loperamide and diphenoxylate are opioids that
- A.
Can cross the BBB
- B.
Can't cross the BBB
Correct Answer
B. Can't cross the BBBExplanation
Diarrhea medications like loperamide and diphenoxylate are opioids that cannot cross the BBB (blood-brain barrier). The BBB is a protective barrier that prevents certain substances from entering the brain. Since these medications cannot cross the BBB, they primarily act on the gastrointestinal tract to alleviate symptoms of diarrhea.Rate this question:
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- 24.
Opioids addicts are itchy because
- A.
They are dirty
- B.
Opioids block the action of allergy medication
- C.
Opioids cause histamine release
- D.
Everyone is allergic to opioids
- E.
Opioids attract bugs to bite
Correct Answer
C. Opioids cause histamine releaseExplanation
Opioids cause histamine release, which can lead to itchiness in addicts. Histamine is a chemical that is released by the body during an allergic reaction, and it can cause symptoms such as itching, redness, and swelling. Opioids can trigger the release of histamine, resulting in itchiness as a side effect. This is why opioids addicts may experience itchiness as a common symptom.Rate this question:
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- 25.
Tolerance develops for all the symptoms except
- A.
Dry throat
- B.
Miosis
- C.
Euphoria
- D.
GI agitation
Correct Answer(s)
B. Miosis
D. GI agitationExplanation
Tolerance develops for most symptoms of drug use over time, meaning that the body becomes less responsive to the effects of the drug. This can lead to a decrease in the intensity or duration of these symptoms. However, miosis (constriction of the pupils) and GI (gastrointestinal) agitation are exceptions to this pattern. Tolerance does not develop for these symptoms, meaning that they may continue to occur at the same intensity even with prolonged drug use.Rate this question:
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- 26.
Opioid withdrawal can cause
- A.
Anxiety
- B.
Sadness
- C.
Diarrhea
- D.
Constipation
- E.
Nausea
Correct Answer(s)
A. Anxiety
B. Sadness
C. DiarrheaExplanation
Opioid withdrawal can cause a range of symptoms, including anxiety, sadness, diarrhea, and nausea. These symptoms occur as a result of the body's dependence on opioids and the sudden removal of these substances. Anxiety and sadness are common emotional symptoms experienced during withdrawal, while diarrhea is a physical symptom caused by the disruption of the digestive system. These symptoms can vary in severity depending on the individual and the extent of their opioid dependence.Rate this question:
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- 27.
Morphine is metabolized in the liver and becomes
- A.
Less active
- B.
More active
- C.
Both less active and more active
- D.
It stays the same until elimination
Correct Answer
C. Both less active and more activeExplanation
Morphine is metabolized in the liver through a process called biotransformation. During this process, morphine is converted into different metabolites, some of which are less active and some of which are more active than the original drug. This means that the effects of morphine can be both decreased and increased as it undergoes metabolism in the liver.Rate this question:
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- 28.
Codeine is a prodrug.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Codeine is a prodrug because it is metabolized in the liver by an enzyme called CYP2D6 into its active form, morphine. The conversion of codeine to morphine is necessary for codeine to exert its analgesic effects. Without this metabolic conversion, codeine would have little to no analgesic activity. Therefore, codeine relies on this biotransformation to become pharmacologically active, making it a prodrug.Rate this question:
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- 29.
CYP2D6 inhibitors like fluoxetine and paroxetine prevent metabolism of codeine and thus
- A.
Make codeine's effects longer lasting
- B.
Make codeine more active
- C.
Prevent codeine from becoming active
Correct Answer
C. Prevent codeine from becoming activeExplanation
CYP2D6 inhibitors like fluoxetine and paroxetine prevent the metabolism of codeine, which means that codeine cannot be converted into its active form. This leads to the prevention of codeine from becoming active and therefore reduces its effects.Rate this question:
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- 30.
Codeine is _____ than morphine.
- A.
More potent
- B.
Less potent
Correct Answer
B. Less potentExplanation
Codeine is less potent than morphine. Potency refers to the strength or effectiveness of a drug. In this case, codeine is considered to be less potent than morphine, meaning that it is not as strong or effective in producing its desired effects.Rate this question:
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- 31.
I want the strongest lollipop. It should be made of
- A.
Morphine
- B.
Codeine
- C.
Heroine
- D.
Fentanyl
- E.
Sufentanyl
Correct Answer
E. SufentanylExplanation
Sufentanyl is the correct answer because it is an extremely potent synthetic opioid that is approximately 5 to 10 times stronger than fentanyl, which itself is already significantly stronger than morphine, codeine, and heroin. Therefore, sufentanyl would be the strongest choice for a lollipop.Rate this question:
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- 32.
Heroine is stronger than morphine because
- A.
It can cross the BBB
- B.
It cant cross the BBB
- C.
It's illegal
Correct Answer
A. It can cross the BBBExplanation
Heroine is stronger than morphine because it can cross the blood-brain barrier (BBB). The blood-brain barrier is a protective barrier that prevents certain substances from entering the brain. However, heroine has the ability to cross this barrier, allowing it to have a stronger effect on the central nervous system compared to morphine. This is why heroine is considered to be more potent and addictive than morphine.Rate this question:
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- 33.
People like percocet because it combines
- A.
Codeine and acetaminophen
- B.
Codeine and aspirin
- C.
Heroine and cocaine
- D.
Morphine and fentanyl
Correct Answer
A. Codeine and acetaminophenExplanation
The reason why people like Percocet is because it combines codeine and acetaminophen. Codeine is an opioid pain medication that provides relief from moderate to severe pain, while acetaminophen is a non-opioid pain reliever and fever reducer. The combination of these two ingredients in Percocet allows for more effective pain relief and increased potency compared to using either medication alone.Rate this question:
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- 34.
Methodone has slow kinetics and thus is ideal for
- A.
Addiction detoxification
- B.
Treating overdose
- C.
Preventing addiction
Correct Answer
A. Addiction detoxificationExplanation
Methadone is a medication commonly used for addiction detoxification because of its slow kinetics. It is a long-acting opioid that helps to reduce withdrawal symptoms and cravings, making it easier for individuals to stop using drugs. Methadone's slow metabolism and elimination from the body allow for a steady and controlled tapering off of opioids, helping individuals overcome their addiction. Therefore, it is an ideal choice for addiction detoxification.Rate this question:
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- 35.
Naloxone and Naltrexone are
- A.
Competitive antagonists
- B.
Non competitive antagonists
- C.
Selective agonists
- D.
Nonselective agonists
Correct Answer
A. Competitive antagonistsExplanation
Naloxone and Naltrexone are classified as competitive antagonists because they compete with the natural agonist (opioids) for binding to the same receptor sites. By binding to the opioid receptors, these drugs prevent the agonists from binding and activating the receptors, thereby blocking their effects. This competitive nature of naloxone and naltrexone distinguishes them from non-competitive antagonists, which bind irreversibly to the receptor and cause a permanent blockade. Additionally, they are not selective agonists because they do not activate the receptors themselves, but rather inhibit the agonist's action.Rate this question:
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- 36.
Naloxone treats
- A.
Addiction
- B.
Overdose
- C.
Boredom
Correct Answer
B. OverdoseExplanation
Naloxone is a medication used to treat opioid overdose. It works by quickly reversing the effects of opioids and restoring normal breathing. When someone overdoses on opioids, such as heroin or prescription painkillers, their breathing can slow down or stop completely, leading to a life-threatening situation. Naloxone can be administered through injection or nasal spray and is often carried by first responders and individuals at risk of overdose. By quickly administering naloxone, it can help reverse the overdose and potentially save a person's life.Rate this question:
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- 37.
Naltrexone treats
- A.
Overdose
- B.
Addiction
- C.
Boredom
Correct Answer
B. AddictionExplanation
Naltrexone is a medication used to treat addiction. It works by blocking the effects of opioids in the brain, which helps to reduce cravings and prevent relapse in individuals who are addicted to opioids or alcohol. Naltrexone is commonly prescribed as part of a comprehensive treatment plan that includes counseling and support. It is not used to treat overdose or boredom, but specifically targets addiction by blocking the pleasurable effects of addictive substances.Rate this question:
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- 38.
___ can be taken orally but ____ must be given parenterally.
- A.
Heroine; Fentanyl
- B.
Naloxone; Naltrexone
- C.
Naltrexone; Naloxone
- D.
Codeine; Sufentanyl
Correct Answer
C. Naltrexone; NaloxoneExplanation
Naltrexone and naloxone are both opioid antagonists used to treat opioid overdose and addiction. However, naltrexone can be taken orally as a pill, while naloxone must be given parenterally, typically through injection or nasal spray. This is because naloxone has poor oral bioavailability, meaning it is not well absorbed when taken by mouth, and therefore needs to be administered directly into the bloodstream for rapid effect.Rate this question:
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Mar 21, 2023Quiz Edited by
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Mar 02, 2009Quiz Created by
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