Probiotics & Immunity Quiz

20 Questions | Total Attempts: 152

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Immunity Quizzes & Trivia

. Please select the best answer from the options provide for each question below. There are twenty questions and a score of at least 60% is needed to obtain 1. 0 category A credit. You have unlimited attempts to successfully complete this quiz.


Questions and Answers
  • 1. 
    Which statement about probiotics in the GI tract is FALSE?
    • A. 

      Probiotic densities increase when proceeding down the GI tract

    • B. 

      Probiotic colonization initially occurs from mother's flora or from the hospital environment

    • C. 

      Probitotics can influence cytokine production

    • D. 

      There is NO difference in flora between caesarean born infants and conventionally (vaginally) born infants

  • 2. 
    Which of the following is NOT a benefit conferred by probiotics?
    • A. 

      Detoxification of xenobiotics

    • B. 

      Biosynthesis of vitamin K

    • C. 

      Fermentation of indigestible dietary fats

    • D. 

      Increasing the bioavailability of all water soluble vitamins and minerals

  • 3. 
    Choose the option that bests completes this statement: A mix of i. ___________ from breast milk that don’t nourish infants are fermented by the infant’s colonic bacteria and selectively ii. __________ the growth/activity of Bifidobacterium spp.
    • A. 

      I. fat soluble vitamins. ii. decrease

    • B. 

      I. trace minerals ii. down regulate

    • C. 

      I. microbes ii. halt

    • D. 

      I. oligosaccharide prebiotics ii. promote

  • 4. 
    Select the best definition of cytokine below.
    • A. 

      A tiny group of very large proteins that are involved with blood clotting

    • B. 

      A small group of specialized phospholipids that carry out cell to cell communication

    • C. 

      Highly specialized immune cells that have pro-inflammatory effects

    • D. 

      A large group of small molecules that travel to other cells, and up regulate or down regulate them

  • 5. 
    Choose the best description of Th1 immunity below.
    • A. 

      Th1 cells drive humoral immunity to fight extracellular pathogens

    • B. 

      Th1 cells reduce mucosal tolerance.

    • C. 

      Th1 cells have no known function.

    • D. 

      Th1 cells drive cellular immunity to fight viruses and other intracellular pathogens.

  • 6. 
    Choose the best description of Th2 immunity below.
    • A. 

      Th2 cells drive cellular immunity to fight intracellular pathogens

    • B. 

      Th2 cells reduce mucosal tolerance.

    • C. 

      Th2 cells have no known function.

    • D. 

      Th2 cells drive humoral immunity and up-regulate antibody production to fight extracellular organisms.

  • 7. 
    Select the statement below about the Th1 and Th2 immune systems that is FALSE. 
    • A. 

      Th1/Th2 cell polarization appears to be irreversible

    • B. 

      Some probiotics appear to influence both Th1 & Th2

    • C. 

      Other Th subsets include Th17, Thc, Th23. and Treg

    • D. 

      Antioxidant status has NO effect on Th1/Th2 balance

  • 8. 
    Select the statement below about the benefits of normal flora that is TRUE.
    • A. 

      Families who consume traditional lactobacillus rich fermented foods experience fewer allergies

    • B. 

      Children with stable gut flora populations have lower incidence of atopic disease

    • C. 

      Specific aberrancies in the intestinal micrbiota may predispose disease in later life

    • D. 

      All of the above are TRUE.

  • 9. 
    Select the statement below about Th1 immunity that is TRUE.
    • A. 

      Th1 cells primarily promote inflammation and activation of cytotoxic T cells

    • B. 

      Th1 rigidity and the potential pathological consequences can be moderated by up regulating production of Th2 dominant cytokines

    • C. 

      Persistent Th1 mediated inflammation of the GI tract is associated with pathologies like Crohn’s disease, H. pylori gastritis, cellular autoimmunity

    • D. 

      All of the above are TRUE.

  • 10. 
    Select the statement below about Th2 immunity that is TRUE.
    • A. 

      The main cells of Th2 include B cells, mast cells and eosinophills

    • B. 

      Th2 dominancy carries a higher risk for infection

    • C. 

      Th2 over activation underlies allergy related Ig E based disease & predisposes to systemic autoimmune disease.

    • D. 

      All of the above are TRUE.

  • 11. 
    Which statement about Th1/Th2 balance is FALSE?
    • A. 

      Th1 & Th2 antagonize each other's actions

    • B. 

      Dendritic cells are key players in determination of Th1/Th2 balance

    • C. 

      . SLE is a heterogeneous disease as Th1 or Th2 can dominate depending on disease stage and presentation

    • D. 

      MS has no association with Th1 and Th2 subsets

  • 12. 
    Select the statement below about Treg immunity that is TRUE.
    • A. 

      Treg cells regulates T helper cell function

    • B. 

      Treg assists with maintaining oral/mucosal tolerance

    • C. 

      Tregs are key to the negative regulatory component of immune responsiveness

    • D. 

      All of the above are TRUE.

  • 13. 
    Choose the best description of the hygiene hypothesis below.
    • A. 

      Hygiene has no effect on immune health.

    • B. 

      There is no change in atopic disease in industrialized countries associated with the excessive hygienic practices.

    • C. 

      Marked decrease in atopic disease in industrialized countries may be associated with the excessive hygienic practices.

    • D. 

      Marked increase in atopic disease in industrialized countries may be associated with the excessive hygienic practices.

  • 14. 
    Which single probiotic strain listed below has demonstrated positive benefit on the pathogenesis on pouchitis?
    • A. 

      B. breve

    • B. 

      B. bifidum

    • C. 

      L. acidophilus

    • D. 

      L. rhamnosus

  • 15. 
    Which probiotic listed  below may not an optimal strain against respiratory infections?
    • A. 

      B. breve

    • B. 

      B. bifidum

    • C. 

      L. acidophilus

    • D. 

      B. animalis

  • 16. 
    Choose the option that bests completes this statement: A study on UC patients found that i. ___________ therapy significantly suppressed ii. __________.  
    • A. 

      I. L. acidophilus. ii. WBC

    • B. 

      I. FOS ii. RBC

    • C. 

      I. pathogenic microbes ii. platelets

    • D. 

      I. B. longum + prebiotics ii. CRP levels

  • 17. 
    Which probiotic strain was shown to significantly increased wheezing in patients with asthma?
    • A. 

      B. breve

    • B. 

      B. bifidum

    • C. 

      L. acidophilus

    • D. 

      L. rhamnosus

  • 18. 
    Select the statement below about Treg immunity that is TRUE.
    • A. 

      Most extensively studied prebiotics are FOS & GOS

    • B. 

      Prebiotics are not digested by the small intestine rather they are anaerobically fermented by the colon to produce short chain fatty acids.

    • C. 

      Short chain fatty acids have significant beneficial impacts on intestinal epithelial cell function

    • D. 

      All of the above are TRUE.

  • 19. 
    Which probiotic strain was given to mothers of high risk infants during the first 6 months of life which resulted in a significant reduction in the prevalence of atopic disease up to the age of 4 years old?
    • A. 

      B. breve

    • B. 

      B. bifidum

    • C. 

      L. acidophilus

    • D. 

      L. rhamnosus

  • 20. 
    Which probiotic strain when administered in combination with mesalmine reduced the number of relapses in patients suffering from Crohn’s disease?
    • A. 

      B. breve

    • B. 

      B. bifidum

    • C. 

      L. acidophilus

    • D. 

      S. boulardii

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