Breast Cancer Quiz: Trivia Questions! Test

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| By Ashleynecole
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Ashleynecole
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Quizzes Created: 3 | Total Attempts: 2,382
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  • 1/43 Questions

    The Sentinal lymph node is biopsied to check for node involvement because it is the first node that receives lymph fluid from the tumor.

    • True
    • False
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About This Quiz

Breast cancer quiz: trivia questions test. Breast Cancer is one of the most common cancer types in women and is easy to treat if detected early. Most cancers are as a result of cells growing abnormally as a result of estrogen exposure. Did you know that even men can get breast cancer? This quiz will help you add to what you already know about the disease. Do give it a try!

Breast Cancer Quiz: Trivia Questions! Test - Quiz

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  • 2. 

    ER/PR positive tumors will respond to endocrine therapy.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Estrogen Receptor/Progesterone Receptor (ER/PR) positive tumors are more common in postmenopausal women. The response shows a more favorable prognosis.

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  • 3. 

    Infiltrating ductal carcinoma is the most common type of breast cancer.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    It is 85-90% of breast cancer cases.

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  • 4. 

    Neoadjuvant chemotherapy should always include an anthracycline +/- a taxane.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Neoadjuvant therapy is used to debulk the tumor for a more successful surgery.

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  • 5. 

    Eventually, every patient with Stage IV breast cancer develops resistance to endocrine therapy. In this case, we should switch the patient to chemotherapy.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Patients with Stage IV breast cancer typically develop resistance to endocrine therapy over time. Endocrine therapy targets hormone receptors in cancer cells, but eventually, cancer cells can become resistant to this type of treatment. When resistance occurs, switching the patient to chemotherapy is often recommended. Chemotherapy uses drugs to kill or slow the growth of cancer cells and can be effective in managing Stage IV breast cancer after endocrine therapy resistance has developed. Therefore, the statement "we should switch the patient to chemotherapy" is true.

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  • 6. 

    Mammograms are a great screening for patients of all ages.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Younger patients may need an ultrasound or MRI to confirm a tumor.

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  • 7. 

    Cure is no longer a goal in Stage IV breast cancer.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    In Stage IV breast cancer, the cancer has spread to other parts of the body, such as the bones, lungs, or liver. At this stage, the goal of treatment shifts from curing the cancer to managing the symptoms, improving quality of life, and prolonging survival. While treatment options are available to control the disease and provide relief, complete eradication of the cancer is generally not achievable. Therefore, the statement that cure is no longer a goal in Stage IV breast cancer is true.

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  • 8. 

    Whether the patient gets a full mastectomy, a segmental or partial mastectomy, or a lumpectomy, survival is the same so surgery is patient preference.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The statement is true because the type of surgery a patient undergoes for breast cancer does not affect their survival rate. Whether they choose a full mastectomy, a segmental or partial mastectomy, or a lumpectomy, the survival outcome remains the same. Therefore, the decision on which surgery to pursue is based on the patient's preference.

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  • 9. 

    Which is a benign breast disease that increases the risk of breast cancer by 4 times?

    • Atypical hyperplasia

    • Proliferative, no atypia

    • Nonproliferative

    • All increase the risk by 4 times.

    Correct Answer
    A. Atypical hyperplasia
    Explanation
    Nonproliferative has no change in risk and proliferative, no atypia only has a slight increase of 1.2-2x.

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  • 10. 

    Regardless if the patient is hormone receptor-positive or negative, HER2-positive tumors that are greater than 1cm or are node-positive should have what on board for therapy?

    • Trastuzumab

    • Bortezomib

    • Bleomycin

    • Mesna

    Correct Answer
    A. Trastuzumab
    Explanation
    Trastuzumab should always be added to HER2 positive tumors. If the tumor is > 2cm or there are positive lymph nodes, pertuzumab should be considered.

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  • 11. 

    Which comprehensive database is the only one that predicts who will respond to chemotherapy?

    • Oncotype DX

    • Adjuvant! Online

    • MammaPrint

    • PAM50

    Correct Answer
    A. Oncotype DX
    Explanation
    All of these are used to aid in treatment decisions.

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  • 12. 

    What is the correct daily dosing for Tamoxifen?

    • 20mg PO

    • 60mg PO

    • 250mg IM

    • 40mg PO

    Correct Answer
    A. 20mg PO
    Explanation
    The correct daily dosing for Tamoxifen is 20mg PO. PO stands for "per os" which means it should be taken orally. Tamoxifen is commonly prescribed for the treatment of breast cancer and is usually taken once daily. The dosage of 20mg is the standard recommended dose for most patients.

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  • 13. 

    Combo therapy doesn't provide any more benefit than monotherapy in the treatment of recurrent or metastatic breast cancer.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    If anything it just adds more cost and side effects.

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  • 14. 

    Modified radical mastectomy must always be followed by radiation.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Breast-conserving therapy (BCT) must always be followed with radiation due to a higher incidence of local recurrence. Types of BCT include a segment or partial mastectomy and lumpectomy.

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  • 15. 

    NCCN guidelines for how often women should get mammograms include:

    • Ages 40 to 44 are optional every year

    • Ages 40 to 44 are annually

    • Ages > 55 are every 2 years

    • Ages 40 and above are annually

    • Ages 50 to 74 are every 2 years

    Correct Answer
    A. Ages 40 and above are annually
    Explanation
    The correct answer is ages 40 and above are annually. According to the NCCN guidelines, women aged 40 and above should get mammograms every year. This is to ensure early detection of breast cancer and increase the chances of successful treatment. Regular mammograms are especially important as women age, as the risk of developing breast cancer increases. Therefore, it is recommended that women aged 40 and above undergo annual mammograms.

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  • 16. 

    The HMT for Cyclophosphamide is:

    • Hemorrhagic cystitis

    • Delayed cardiotoxicity

    • Peripheral Neuropathy

    • Complete alopecia

    Correct Answer
    A. Hemorrhagic cystitis
    Explanation
    Can occur months later, patient needs to hydrate and urinate frequently.

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  • 17. 

    Any age woman who is ER+ and/or PR+ should receive Tamoxifen when?

    • After chemotherapy

    • After surgery but before chemotherapy

    • Before surgery and chemotherapy

    • Tamoxifen is not the correct therapy for this patient.

    Correct Answer
    A. After chemotherapy
    Explanation
    The correct answer is "After chemotherapy" because Tamoxifen is a hormonal therapy commonly used in the treatment of hormone receptor-positive (ER+ and/or PR+) breast cancer. It works by blocking the effects of estrogen on breast cancer cells. Chemotherapy is typically given before hormonal therapy to shrink tumors and kill cancer cells, so it is important to complete chemotherapy before starting Tamoxifen.

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  • 18. 

    Select all that are risk factors for breast cancer:

    • Early menarche (

    • Nuliparity

    • Late menopause (>54 years old)

    • No previous chest irradiation

    • Young age

    • Increased breast density

    Correct Answer(s)
    A. Early menarche (
    A. Nuliparity
    A. Late menopause (>54 years old)
    A. Increased breast density
    Explanation
    Previous chest irradiation is a risk factor. Increasing age is a risk factor.

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  • 19. 

    A tumor that is ____ and has no axillary node involvement has a favorable prognosis.

    • < 2cm

    • < 1cm

    • < 3 cm

    • < 4cm

    • < 5cm

    Correct Answer
    A. < 2cm
    Explanation
    A tumor that is less than 2cm in size and has no axillary node involvement has a favorable prognosis. This means that the tumor is relatively small and has not spread to the lymph nodes, indicating a lower likelihood of metastasis and better chances of successful treatment and survival.

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  • 20. 

    Dosing LH-RH every 3 months is sufficient for ovarian suppression.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Only monthly dosing can guarantee ovarian suppression.

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  • 21. 

    What is the gene that, when mutated, increases the risk for breast cancer?

    Correct Answer
    BRCA
    BRCA1
    BRCA2
    Explanation
    If a patient is young age and has a family history of breast cancer, consider genetic testing.

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  • 22. 

    Patients who are ER+/PR+ should always receive endocrine therapy prior to chemo.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    They should always receive endocrine therapy AFTER chemo.

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  • 23. 

    A tumor that is ______ and has no axillary involvement has a poorer prognosis.

    • > 5cm

    • >4 cm

    • > 3cm

    • > 2cm

    • > 6cm

    Correct Answer
    A. > 5cm
    Explanation
    A tumor that is larger than 5cm and has no axillary involvement has a poorer prognosis. This means that when the tumor size exceeds 5cm and there is no spread to the axillary lymph nodes, the chances of a more negative outcome or prognosis for the patient are higher. The size of the tumor plays a significant role in determining the severity and aggressiveness of the cancer, and when it surpasses 5cm, it indicates a more advanced stage of the disease.

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  • 24. 

    Which guideline recommends clinical breast exams?

    • NCCN

    • ACS

    • USPTF

    • None of them do.

    Correct Answer
    A. NCCN
    Explanation
    NCCN recommends clinical breast exams from ages 25 to 40 every 1 to 3 years and annually after the age of 40.

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  • 25. 

    Carboplatin is included in therapy for:

    • HER-2/neu + patients

    • ER/HR + patients

    • Adjuvant endocrine therapy

    • Node negative; < 1 cm

    Correct Answer
    A. HER-2/neu + patients
    Explanation
    Carboplatin is included in therapy for HER-2/neu + patients because HER-2/neu is a protein that promotes the growth of cancer cells. Carboplatin is a chemotherapy drug that works by interfering with the DNA in cancer cells, preventing them from growing and dividing. Therefore, it is used specifically in patients who have HER-2/neu positive breast cancer to target and inhibit the growth of these cancer cells.

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  • 26. 

    An aromatase inhibitor is a good choice therapy for treatment in a premenopausal Stage IV patient.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Aromatase inhibitors should not be used alone for this patient.

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  • 27. 

    The size of the primary tumor is the most important prognostic factor.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    The number of involved axillary lymph nodes is the most important prognostic factor.

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  • 28. 

    What is the cutoff for how many involved lymph nodes a patient can have before the survival rate starts decreasing?

    • 3 nodes

    • 2 nodes

    • 4 nodes

    • 5 nodes

    Correct Answer
    A. 3 nodes
    Explanation
    1-3 nodes involved has a better prognosis whereas 4+ nodes involved has a poorer prognosis.

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  • 29. 

    Which of these drugs is an anthracycline?

    • Doxorubicin

    • Epirubicin

    • Irinotecan

    • Ifosfamide

    • Cyclophosphamide

    Correct Answer(s)
    A. Doxorubicin
    A. Epirubicin
    Explanation
    Delayed cardiotoxicity is the DLT and HMT. Baseline EF should be obtained prior to therapy. There are lifetime maximum doses.

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  • 30. 

    The treatment of choice for postmenopausal Stage IV breast cancer is:

    • Anastrozole + fulvestrant

    • Letrozole + Palbociclib

    • Taomoxifen

    • None of these options are a good therapy choice.

    Correct Answer
    A. Anastrozole + fulvestrant
    Explanation
    AI therapy is preferred over Letrozole + Palbociclib because we don't know how that therapy actually affects survival.

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  • 31. 

    Which guideline does not provide any information on breast awareness?

    • USPTF

    • NCCN

    • ACS

    • They all do.

    Correct Answer
    A. USPTF
    Explanation
    USPTF has no comment on breast awareness.

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  • 32. 

    Anthracycline-containing regimens are preferred for node + breast cancer but are not more effective in HER-2/neu+ patients.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Anthracycline-containing regimens may be MORE effective in HER-2/neu+ patients.

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  • 33. 

    A patient with stage IV breast cancer and bone metastases is started on Pamidronate therapy. What are some counseling points for this patient?

    • Calcium and Vitamin D supplementation should be used daily.

    • A dental exam needs to be done prior to therapy and no dental procedures while using this medication.

    • Data supports the the use of this drug for up to 2 years, but may benefit longer.

    • This drug can cause neutropenia

    • This drug should be administered with food.

    Correct Answer(s)
    A. Calcium and Vitamin D supplementation should be used daily.
    A. A dental exam needs to be done prior to therapy and no dental procedures while using this medication.
    A. Data supports the the use of this drug for up to 2 years, but may benefit longer.
    Explanation
    Patients receiving Pamidronate therapy should be counseled to take daily calcium and vitamin D supplementation to prevent bone loss. They should also undergo a dental exam before starting the therapy and avoid any dental procedures while using the medication, as Pamidronate can cause jaw problems. The data suggests that this drug can be used for up to 2 years, but longer use may also provide benefits.

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  • 34. 

    Select all that are true for Ductal Carcinoma In Situ (DCIS).

    • It is Stage 0 in breast cancer

    • It has pre-malignant lesions

    • Lumpectomy with XRT is the preferred therapy

    • It is not a pre-malignant lesion

    • It is Stage I in breast cancer

    Correct Answer(s)
    A. It is Stage 0 in breast cancer
    A. It has pre-malignant lesions
    A. Lumpectomy with XRT is the preferred therapy
    Explanation
    Although lumpectomy with XRT (radiotherapy) is preferred, the patient could also have a mastectomy or lumpectomy followed by observation.

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  • 35. 

    Select all that are true for Paclitaxel:

    • DLT is peripheral neuropathy

    • HMT is alopecia

    • Premeds need to be used to prevent hypersensitiviy.

    • HMT is edema

    • DLT is diarrhea

    Correct Answer(s)
    A. DLT is peripheral neuropathy
    A. HMT is alopecia
    A. Premeds need to be used to prevent hypersensitiviy.
    Explanation
    Edema is the HMT for Docetaxel

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  • 36. 

    Which of these drugs is a taxane?

    • Eribulin

    • Paclitaxel

    • Docetaxel

    • Vinblastine

    • Vincristine

    Correct Answer(s)
    A. Eribulin
    A. Paclitaxel
    A. Docetaxel
    Explanation
    Eribulin can be used for taxane resistance.

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  • 37. 

    Women who are on tamoxifen and become post-menopausal should:

    • Consider switching to an aromatase inhibitor

    • Continue tamoxifen

    • Stop tamoxifen therapy with no new therapy

    • Only need 5 years of therapy

    Correct Answer(s)
    A. Consider switching to an aromatase inhibitor
    A. Continue tamoxifen
    Explanation
    The patient can either switch or remain on tamoxifen, but they need to be on the therapy for a total of 10 years.

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  • 38. 

    ACS guidelines for how often women should get mammograms include:

    • Ages 40 to 44 are optional every 1 year.

    • Ages 45 to 54 are annually.

    • Ages > 55 are every 2 years.

    • Annually after the age of 40.

    • Ages 40 to 49 is an individual decision.

    Correct Answer(s)
    A. Ages 40 to 44 are optional every 1 year.
    A. Ages 45 to 54 are annually.
    A. Ages > 55 are every 2 years.
    Explanation
    The ACS guidelines recommend that women aged 40 to 44 have the option to get mammograms every 1 year. For women aged 45 to 54, the guidelines recommend getting mammograms annually. Women over the age of 55 are advised to get mammograms every 2 years. Therefore, the correct answer includes these recommendations from the ACS guidelines.

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  • 39. 

    Adjuvant endocrine therapy for postmenopausal women includes:

    • Aromatase inhibitor for 5 years

    • Tamoxifen therapy for a total of 10 years

    • Tamoxifen therapy then aromatase inhibitor therapy for 10 years

    • No adjuvant therapy is needed since this patient is postmenopausal

    • Aromatase inhibitor for 10 years

    Correct Answer(s)
    A. Aromatase inhibitor for 5 years
    A. Tamoxifen therapy for a total of 10 years
    A. Tamoxifen therapy then aromatase inhibitor therapy for 10 years
    Explanation
    The correct answer is a combination of aromatase inhibitor therapy for 5 years and tamoxifen therapy for a total of 10 years. This is because adjuvant endocrine therapy for postmenopausal women with hormone receptor-positive breast cancer typically involves a sequence of these two types of medications. Aromatase inhibitors are initially used for 5 years to block the production of estrogen, followed by tamoxifen therapy for an additional 5 years to further reduce the risk of recurrence. In some cases, tamoxifen therapy may be given first for 2-3 years, followed by aromatase inhibitor therapy for a total duration of 10 years.

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  • 40. 

    USPTF screening recommendations suggest women get mammograms at what age?

    • Ages 40 to 49 is an individual decision

    • Ages 50 to 74 should get one every year

    • Ages 40 and above should get one annually

    • Ages 55 and above should get one every 2 years

    • Ages 40 to 44 are optional every year

    Correct Answer(s)
    A. Ages 40 to 49 is an individual decision
    A. Ages 50 to 74 should get one every year
    Explanation
    The USPTF screening recommendations suggest that women between the ages of 40 to 49 should make an individual decision regarding mammograms. However, for women aged 50 to 74, it is recommended that they get a mammogram every year.

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  • 41. 

    Which antidepressants are safe to take with Tamoxifen?

    • Venlafaxine

    • Citalopram

    • Escitalopram

    • Sertraline

    • Paroxetine

    • Fluoxetine

    Correct Answer(s)
    A. Venlafaxine
    A. Citalopram
    A. Escitalopram
    A. Sertraline
    Explanation
    Venlafaxine, Citalopram, Escitalopram, and Sertraline are safe to take with Tamoxifen because they do not significantly interact with the drug and are not known to increase the risk of adverse effects or decrease the effectiveness of Tamoxifen. However, caution should still be exercised and it is always recommended to consult with a healthcare professional before starting any new medication. Fluoxetine and Paroxetine, on the other hand, may interact with Tamoxifen and should be avoided or used with caution under medical supervision.

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  • Mar 22, 2023
    Quiz Edited by
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    Ashleynecole
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