The given sequence is -9, -3, 21, 2. This sequence seems to follow a pattern where each number is obtained by multiplying the previous number by -3. Starting with -9, we multiply it by -3 to get -27, then multiply -27 by -3 to get 81, and finally multiply 81 by -3 to get -243. However, the next number in the sequence is 2, which breaks the pattern. Therefore, it is likely that there is an error or inconsistency in the sequence, and the given answer of -9 may not be correct.