Final Exam Pcol2 Mw 8:30-10am

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1. Can Heparin be used for pregnant patients?
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Final Exam Pcol2 Mw 8:30-10am - Quiz

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2. This drug inhibits vitamin K epoxide reductase.
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3. Which statement is TRUE on the diagnosis of MI?
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4. What are the standard secondary prevention treatment drugs to be initiated following an acute MI?
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5. It is a monoclonal antibody
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6. Clinical uses of Heparin
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7. Antidote for Heparin toxicity or overdose
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8. The following are glycoprotein IIb/IIIa receptor inhibitors EXCEPT:
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9. The following are ADP receptor antagonists EXCEPT:
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10. If a fibrinolytic drug is used for treatment of this woman's acute myocardial infarction, which of the following adverse drug effects is most likely to occur?
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11. Fractionated preparations of heparin of molecular weight 2000-6000
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12. A protein complex on the surface of platelets
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13. MOA of Heparin
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14. Laboratory test used to monitor the anticoagulant effect of warfarin which is prolonged when drug effect is adequate.
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15. Unfractionated heparin has a molecular weight range of 5000-30000
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16. Which clotting factor/s is/are inhibited by Oral Anticoagulant drugs?
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17. Which of the following drugs accelerates the conversion of plasminogen to plasmin?
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18. System of serine proteases and substrates in the blood that provides rapid generation of clotting factors in response to blood vessel damage
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19. Site of Action for Heparin
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20. Choose the correct statement about ADP receptor antagonists
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21. It is a phosphodiesterase-3 inhibitor
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22. A hypercoagulable state plus thrombocytopenia that occurs in a small number of individuals treated with unfractionated heparin
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23. If this patient undergoes a percutaneous coronary angiography procedure and placement of a stent in a coronary blood vessel, she may be given eptifibatide. Which of the following most accurately describes the mechanism of eptifibatide anticlotting action?
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24. An endogenous anticlotting protein that irreversibly inactivates thrombin and factor Xa.
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25. When activated, it aggregates platelets primarily by binding to fibrin
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26. Which statement is TRUE on the clinical use of Thrombolytics?
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27. Choose the correct statement on Inhibitors of Phosphodiesterase 3.
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28. Its enzymatic action is markedly accelerated by the heparins
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29. Laboratory test used to monitor the anticoagulant effect of unfractionated heparin and direct thrombin inhibitors which is prolonged when drug effect is adequate
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30. CASE JR is an 87-year-old man with a chief complaint of shortness of breath, productive cough, and fever. This is his second admission to the hospital in the last month for a similar complaint. His past medical history includes BPH, congestive heart failure (CHF), and hypertension. His home medications are fluconazole, citalopram, furosemide, metoprolol, aspirin, and lisinopril. JR is admitted with nasal cannula oxygen. His diagnosis is pneumonia. Labs are pertinent for creatinine clearance of 41 mL/min and sputum culture positive for Pseudomonas aeruginosa. Bacterial sensitivities are not back yet. JR is ready for discharge from the hospital when he develops multiple episodes of diarrhea. Stool culture is positive for Clostridium difficile. The optimal initial treatment of choice is
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31. Site of Action for Warfarin
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32. Which statement is TRUE? (You can tick more than once)
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33. Substances that increase intracellular cyclic adenosine monophosphate –cAMP- inhibit ______.
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34. A cell surface protein involved in platelet cross-linking.
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35. It is activated by endogenous factors such as thromboxane A2, ADP and serotonin which initiates a signaling cascade
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36. Which drug may be a problem given that the patient has DM?
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37. Case: A 65-year-old man is brought to the emergency department 30 min after the onset of right-sided weakness and aphasia (difficulty speaking). Imaging studies ruled out cerebral hemorrhage as the cause of his acute symptoms of stroke.   Over the next 2 d, the patient's symptoms resolved completely. To prevent a recurrence of this disease, the patient is most likely to be treated indefinitely with which of the following?
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38. Which clotting factor/s is/are inhibited by Heparin?
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39. Case:  A 65-year-old man is brought to the emergency department 30 min after the onset of right-sided weakness and aphasia (difficulty speaking). Imaging studies ruled out cerebral hemorrhage as the cause of his acute symptoms of stroke. Prompt administration of which of the following drugs is most likely to improve this patient's clinical outcome?
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40. Which statement is true about Warfarin?
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41. CASE JR is an 87-year-old man with a chief complaint of shortness of breath, productive cough, and fever. This is his second admission to the hospital in the last month for a similar complaint. His past medical history includes BPH, congestive heart failure (CHF), and hypertension. His home medications are fluconazole, citalopram, furosemide, metoprolol, aspirin, and lisinopril. JR is admitted with nasal cannula oxygen. His diagnosis is pneumonia. Labs are pertinent for creatinine clearance of 41 mL/min and sputum culture positive for Pseudomonas aeruginosa. Bacterial sensitivities are not back yet. JR is not responding to your choice of antibiotics and the physician adds tobramycin to the regimen. Using the ODA method, his tobramycin peak at steady state is 17.2 ug/mL and trough of 1.4 ug/mL. Based on these levels, the best recommendation would be to
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42. Goals of Treatment for MI (you can tick more than once)
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43. The following are Antiplatelet drugs EXCEPT:
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44. CASE JR is an 87-year-old man with a chief complaint of shortness of breath, productive cough, and fever. This is his second admission to the hospital in the last month for a similar complaint. His past medical history includes BPH, congestive heart failure (CHF), and hypertension. His home medications are fluconazole, citalopram, furosemide, metoprolol, aspirin, and lisinopril. JR is admitted with nasal cannula oxygen. His diagnosis is pneumonia. Labs are pertinent for creatinine clearance of 41 mL/min and sputum culture positive for Pseudomonas aeruginosa. Bacterial sensitivities are not back yet.   The optimal choice of antibiotic(s) for the treatment of JR's pneumonia is (are)
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45. CASE JR is an 87-year-old man with a chief complaint of shortness of breath, productive cough, and fever. This is his second admission to the hospital in the last month for a similar complaint. His past medical history includes BPH, congestive heart failure (CHF), and hypertension. His home medications are fluconazole, citalopram, furosemide, metoprolol, aspirin, and lisinopril. JR is admitted with nasal cannula oxygen. His diagnosis is pneumonia. Labs are pertinent for creatinine clearance of 41 mL/min and sputum culture positive for Pseudomonas aeruginosa. Bacterial sensitivities are not back yet. After 2 days on his new antibiotic, JR has developed a major drug interaction. Which of the following is the major sign/symptom of this drug interaction?
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46. CASE JR is an 87-year-old man with a chief complaint of shortness of breath, productive cough, and fever. This is his second admission to the hospital in the last month for a similar complaint. His past medical history includes BPH, congestive heart failure (CHF), and hypertension. His home medications are fluconazole, citalopram, furosemide, metoprolol, aspirin, and lisinopril. JR is admitted with nasal cannula oxygen. His diagnosis is pneumonia. Labs are pertinent for creatinine clearance of 41 mL/min and sputum culture positive for Pseudomonas aeruginosa. Bacterial sensitivities are not back yet. Five days later, JR complains of flank pain and pain on urination. His urine culture is positive for Enterococcus faecium. The best choice to treat his urinary tract infection is
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47. Which statement/s is/are TRUE about Rivaroxaban and Apixaban? (you can tick more than once)
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48. Choose the General Approaches in the treatment and management of MI? (you can tick more than once)
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49. Which statement/s is/are TRUE about Thrombolytic Agents? (you can tick more than once)
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50. Which statement/s is/are TRUE? (you can tick more than once)
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Can Heparin be used for pregnant patients?
This drug inhibits vitamin K epoxide reductase.
Which statement is TRUE on the diagnosis of MI?
What are the standard secondary prevention treatment drugs to be...
It is a monoclonal antibody
Clinical uses of Heparin
Antidote for Heparin toxicity or overdose
The following are glycoprotein IIb/IIIa receptor inhibitors EXCEPT:
The following are ADP receptor antagonists EXCEPT:
If a fibrinolytic drug is used for treatment of this woman's acute...
Fractionated preparations of heparin of molecular weight 2000-6000
A protein complex on the surface of platelets
MOA of Heparin
Laboratory test used to monitor the anticoagulant effect of warfarin...
Unfractionated heparin has a molecular weight range of 5000-30000
Which clotting factor/s is/are inhibited by Oral Anticoagulant drugs?
Which of the following drugs accelerates the conversion of plasminogen...
System of serine proteases and substrates in the blood that provides...
Site of Action for Heparin
Choose the correct statement about ADP receptor antagonists
It is a phosphodiesterase-3 inhibitor
A hypercoagulable state plus thrombocytopenia that occurs in a small...
If this patient undergoes a percutaneous coronary angiography...
An endogenous anticlotting protein that irreversibly inactivates...
When activated, it aggregates platelets primarily by binding to fibrin
Which statement is TRUE on the clinical use of Thrombolytics?
Choose the correct statement on Inhibitors of Phosphodiesterase 3.
Its enzymatic action is markedly accelerated by the heparins
Laboratory test used to monitor the anticoagulant effect of...
CASE ...
Site of Action for Warfarin
Which statement is TRUE? (You can tick more than once)
Substances that increase intracellular cyclic adenosine monophosphate...
A cell surface protein involved in platelet cross-linking.
It is activated by endogenous factors such as thromboxane A2, ADP and...
Which drug may be a problem given that the patient has DM?
Case: A 65-year-old man is brought to the emergency department 30...
Which clotting factor/s is/are inhibited by Heparin?
Case:  ...
Which statement is true about Warfarin?
CASE ...
Goals of Treatment for MI (you can tick more than once)
The following are Antiplatelet drugs EXCEPT:
CASE ...
CASE ...
CASE ...
Which statement/s is/are TRUE about Rivaroxaban and Apixaban? (you can...
Choose the General Approaches in the treatment and management of MI?...
Which statement/s is/are TRUE about Thrombolytic Agents? (you can tick...
Which statement/s is/are TRUE? (you can tick more than once)
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