Immunity First
.
- 1.
-ONe of the following sentences is not true regarding the spleen:
- A.
A)splenectomy patient are more immunocompromized against encapsolated bacteria
- B.
B)90% of lymph is stored in the spleen ,so it is a good source of lymphocyte
- C.
C)the spleen recieve lymphocyte by blood because it doesnt have lymphatic vessels .
- D.
None of the above
Correct Answer
B. B)90% of lymph is stored in the spleen ,so it is a good source of lymphocyte -
- 2.
- One of the following pairs is mismatched:
- A.
L-selectin ,found in WBC surfacr
- B.
MAC integrin ligand , VCAM-1 and endothelium
- C.
Selectin , primary adhesion
- D.
Stabilization of immune synapse , LFA-1
Correct Answer
B. MAC integrin ligand , VCAM-1 and endothelium -
- 3.
-The integrin on lymphocyte they will be developed by stimulation of:
- A.
IL-2 and IL -10
- B.
Hormones
- C.
Ag -Ab complex
- D.
IL-1, TNF
Correct Answer
B. Hormones -
- 4.
- splenctomised patients must undergo through life-long prophylactic antibiotics :
- A.
True
- B.
False
Correct Answer
A. True -
- 5.
which one of the following is an example of passive immunity ?
- A.
Immune respons after viral infection
- B.
Hepatitis B vaccine
- C.
anti-rabies antibodies after a dog bite
- D.
None of the above
Correct Answer
C. anti-rabies antibodies after a dog bite -
- 6.
Which one of the following organs is an immunologicaly privileged site ?
- A.
Sternum
- B.
Cornea
- C.
thymus
- D.
Liver
Correct Answer
B. Cornea -
- 7.
Di george syndrome is :
- A.
Defect that results in immune suppression and convulsions
- B.
Abscence of thymus gland and hypercalcemia
- C.
Abscence of thymus gland and hypocalcemia
- D.
A and c
Correct Answer
D. A and c -
- 8.
Choose the incorrect matching :
- A.
IgM: marker for recent or acute infection.
- B.
IgG : the most abundant Ig in the serum
- C.
IgA: dimer in the serum
- D.
IgE: mediates type 1 hypersensetivity reaction
- E.
IgD : work as a B cell receptor
Correct Answer
C. IgA: dimer in the serum -
- 9.
Choose the Incorrect sentence :
- A.
Not all Igs are antibodies.
- B.
. IgG is the only one that can opsonize microbes and toxins.
- C.
IgM has the highest molecular weight.
- D.
IgM levels persist in small amount throughout life after the primary response.
Correct Answer
D. IgM levels persist in small amount throughout life after the primary response. -
- 10.
Overreaction of the immune system against environmental substances is called :
- A.
Hypersensetivity
- B.
Allergey
- C.
Autoimmune disease
- D.
.Immunodeficiency disease
Correct Answer
B. Allergey -
- 11.
Valence of antibodody for IgM is (number of antigen binding sites) :
- A.
2
- B.
5
- C.
8
- D.
10
Correct Answer
D. 10 -
- 12.
The first antibody to be produced by the B cells during an infection is:
- A.
IgM
- B.
IgG
- C.
IgA
- D.
IgE
Correct Answer
A. IgM -
- 13.
Regarding the adaptive immunity, choose the Incorrect sentence ?
- A.
.Adaptive immunity is slower than the innate immunity but more specific.
- B.
It is the third line of defense
- C.
. Cell mediated immune response eliminate extracellular microbes
- D.
Has memory unlike the innate immunity.
Correct Answer
C. . Cell mediated immune response eliminate extracellular microbes -
- 14.
)The type of vaccine in which a killed or inactivated disease causing agent is used :
- A.
Hepatitis B vaccine
- B.
.Polio vaccine
- C.
MMR vaccine
Correct Answer
B. .Polio vaccine -
- 15.
The type of immunoglobuline that can cross the placenta during pregnancy is:
- A.
IgM
- B.
. IgG
- C.
IgA
- D.
IgE
Correct Answer
B. . IgG -
- 16.
Which one the following is most professional APC
- A.
Neutrophils
- B.
Macrophages
- C.
Dendritic cells
- D.
Mast cells
Correct Answer
C. Dendritic cells -
- 17.
Extensive allelic polymorphism is found in MHC ?
- A.
Class || beta 2 domain
- B.
class | alpha 3 domain
- C.
beta 2- microglobulin
- D.
DRbeta
Correct Answer
D. DRbeta -
- 18.
The drug that suppresses immunity by blocking the Calmodulin-Calcineurin signaling pathway is:
- A.
Cyclosporine
- B.
)Azathioprine
- C.
Mycophenolate mofetil
- D.
Leflunomide
Correct Answer
A. Cyclosporine -
- 19.
Which of the following is correctly matched
- A.
MHC-class 1 — CD8 T-Cells
- B.
MHC-class 2 - CD24 T-Cells
- C.
B17-1/B17-2 — CD28 T-Cells
- D.
Two answers are correct
Correct Answer
A. MHC-class 1 — CD8 T-Cells -
- 20.
Adaptive and innate immune systems are completely separated?
- A.
True
- B.
False
Correct Answer
B. False -
- 21.
In the first line of defence we can find:
- A.
Monocytes
- B.
Natural killer
- C.
Eosinophils
- D.
Non of the above
Correct Answer
D. Non of the above -
- 22.
The concept if vaccination is to introduce the:
- A.
Natural Active
- B.
Artificial Active
- C.
Natural passive
- D.
Artificial passive
Correct Answer
B. Artificial Active -
- 23.
In organ transplantation we :
- A.
Suppress the immune system
- B.
Activate the immune system
- C.
Non of the above
- D.
Both are correct
Correct Answer
A. Suppress the immune system -
- 24.
Ankylosing spndylitis is Highly associated with :
- A.
HLA-B27
- B.
HLA- A1
- C.
HLA-DQ2
- D.
HLA-DR2
Correct Answer
A. HLA-B27 -
- 25.
One of the follong is not an Antigen presenting Cell:
- A.
B cell
- B.
Dendritic cell
- C.
Macrophages
- D.
ICAM
Correct Answer
D. ICAM -
- 26.
which of the following is responsible of the inhibtion of T Cells :
- A.
Cd3
- B.
CD22
- C.
IL-2
- D.
CLAT-4
Correct Answer
D. CLAT-4 -
- 27.
How many CDR in T cell receptor ?
- A.
4
- B.
3
- C.
8
- D.
6
Correct Answer
D. 6 -
- 28.
The gene segment that isn't transcribed during recombination of the light chain is?
- A.
)V
- B.
D
- C.
C
- D.
J
Correct Answer
B. D -
- 29.
TdT enzyme will be active in which of these stages?
- A.
Stem cell >>>>> pro b cell
- B.
pro >>>>>> pre b cell
- C.
Pre>>>> immature b cell
- D.
mature naïve >>>> mature effector b cell
Correct Answer
B. pro >>>>>> pre b cell -
- 30.
مين بتتوقع الفايز بكاس العالم (على الهامش :واضع السؤال مدريدي)
- A.
البرازيل
- B.
الارجنتين
- C.
فرنسا
- D.
البرتغال
Correct Answer
D. البرتغال -
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Current Version
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Jun 29, 2018Quiz Edited by
ProProfs Editorial Team -
Jun 29, 2018Quiz Created by
Yousef
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