Microbiology Final Pt.4

39 Questions | Total Attempts: 125

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Microbiology Quizzes & Trivia

Questions and Answers
  • 1. 
    Which type(s) of antigen-presenting cell can activate T cells?
    • A. 

      Macrophages

    • B. 

      B cells

    • C. 

      Dendritic cells

    • D. 

      All of the choices

  • 2. 
    Chemotherapeutic agents that are chemically modified natural products of microorganisms are most specifically referred to as ___
    • A. 

      Antimicrobial agents

    • B. 

      Synthetic drugs

    • C. 

      Antibiotics

    • D. 

      Semisynthetic drugs

  • 3. 
    Which of the following is likely to have the most toxic side effects to humans
    • A. 

      Inhibitors of cell wall synthesis

    • B. 

      Inhibitors of protein synthesis

    • C. 

      Disrupters of cell membrane structure

    • D. 

      Inhibitors of DNA synthesis

  • 4. 
    Development of drug resistance is NOT discouraged by
    • A. 

      Use of a high enough concentration of the drug to destroy any spontaneous resistant mutants that might arise

    • B. 

      Use of two drugs simultaneously with the hope that each will prevent the emergence of resistance to the other

    • C. 

      Avoidance of indiscriminate use of drugs

    • D. 

      Widespread use of broad-spectrum drugs

  • 5. 
    Type ___ hypersensitivity involves delayed, cell-mediated immune reactions
    • A. 

      I

    • B. 

      II

    • C. 

      III

    • D. 

      IV

  • 6. 
    Which of the following is used to reduce or eliminate the source of an infection?
    • A. 

      Treatment of sewage to reduce water contamination

    • B. 

      Destruction of vectors by spraying insecticides

    • C. 

      Destruction of an animal reservoir of the infectious agent

    • D. 

      All of the choices are used to reduce o eliminate the source of an infection

  • 7. 
    The most selective antibacterial agents are those that interfere with bacterial cell wall synthesis. This is because
    • A. 

      Bacterial cell walls have a unique structure not found in eukaryotic host cells

    • B. 

      Bacterial cell wall synthesis is easily inhibited wheras eukaryotic cell wall synthesis is more resistant to the action of the drugs

    • C. 

      Euk cells do not take up the drugs

    • D. 

      Euk cells inactivate the drugs before they can do any damage

  • 8. 
    A ___ rate measures the number of individuals who become ill as a result of a specific disease within a suceptible population during a specific time period
    • A. 

      Prevalence

    • B. 

      Morbidity

    • C. 

      Mortality

    • D. 

      Index

  • 9. 
    Which of the following is the major reason why it has been difficult to treat viral infections with chemotherapeutic agents?
    • A. 

      Viral metabolism resembles that of their hosts so there is no selective point of attack

    • B. 

      Viruses use the metabolic machinery of their hosts which limits many of the potential points of attack

    • C. 

      Viruses have no metabolism and therefore offer no selective point of attack

    • D. 

      Actually, viruses are not difficult to treat with chemotherapeutic agents

  • 10. 
    The concentration of an antimicrobial drug that is reached in the body will depend on 
    • A. 

      The amount of drug administered

    • B. 

      The route of administration and speed of uptake

    • C. 

      The rate at which the drug is cleared or eliminated from the body

    • D. 

      All of the above

  • 11. 
    An epidemic is 
    • A. 

      A disease that maintains a steady low level frequency

    • B. 

      When a disease occurs occasionally and at erratic intervals in the human population

    • C. 

      A sudden increase in the occurrence of a disease above the expected level

    • D. 

      A sudden unexpected occurrence of a disease in a limited segment of a population

  • 12. 
    Antibiotics that are given by injection are said to have a (n) ____ route of administration
    • A. 

      Oral

    • B. 

      Venal

    • C. 

      Parenteral

    • D. 

      Topical

  • 13. 
    Genes for drug resistance may be present 
    • A. 

      On the chromosome

    • B. 

      On plasmids

    • C. 

      On mitochondrial DNA

    • D. 

      Both on the chromosome and on plasmids

    • E. 

      Both on plasmids and on mitochondrial DNA

  • 14. 
    The ___ rate refers to the total number of individuals infected at any one time regardless of when the disease began
    • A. 

      Prevalence

    • B. 

      Morbidity

    • C. 

      Mortality

    • D. 

      Index

  • 15. 
    Which of the following ais (are) used by microorganisms to become resistant to a particular drug
    • A. 

      Enzymatic inactivation of the drug

    • B. 

      Exclusion of the drug from the cell

    • C. 

      An alternate metabolic pathway that bypasses the drug-sensitive step

    • D. 

      All of the above

  • 16. 
    Which type of epidemic usually results from a single contaminated source such as food
    • A. 

      Propagated

    • B. 

      Common-source

    • C. 

      Herd

    • D. 

      Sporadic

  • 17. 
    ____ immunity is an epidemiological concept that explains the resitance of a population to infection and the spread of an infectious organism due to the immunity of a high percentage of the population
    • A. 

      Natural

    • B. 

      Experimental

    • C. 

      Herd

    • D. 

      Innate

  • 18. 
    T cells attack
    • A. 

      Host cells that have parasitized by microorganisms

    • B. 

      Transplanted tissue cells from one host to another

    • C. 

      Cancer cells

    • D. 

      All the choices

  • 19. 
    Which of the following contributes to the emergence of new diseases
    • A. 

      Rapid transportation systems and the mobility of the population

    • B. 

      Ecological disruption such as the loss of predators and the destruction of rain forests

    • C. 

      Increased drug usage and sexual promiscuity

    • D. 

      All of the above

  • 20. 
    Which of the following affects the size of the clear zone in a disk diffusion test of antimicrobial susceptibility
    • A. 

      The initial concentration of the drug

    • B. 

      The solubility of the drug

    • C. 

      The diffusion rate of the drug

    • D. 

      All of the above

  • 21. 
    The immune system normally discriminates between ____ antigens
    • A. 

      Self and nonself

    • B. 

      B and t cells

    • C. 

      Humoral and cell-0mediated

    • D. 

      Primary and secondary response

  • 22. 
    Which of the following statements about antimetabolite compounds is NOT correct
    • A. 

      An antimetabolite blocks metabolic pathways

    • B. 

      Antimetabolites resemble a metabolite

    • C. 

      Antimetabolites compete for enzymes active site

    • D. 

      Normally enzymes are able to recognize the antimetabolite and avoid it

  • 23. 
    Immunity that is mediated by T lymphocytes is characterized as 
    • A. 

      Cell-mediated

    • B. 

      Antibody-mediated

    • C. 

      Innate acquired

    • D. 

      Innate natural

    • E. 

      Humoral

  • 24. 
    Which of the following is the major focus of epidemiologists
    • A. 

      The discovery of factors essential to disease occurrence

    • B. 

      The development of methods for disease prevention

    • C. 

      Measuring the level of resistance to antimicrobial agents

    • D. 

      Both the discovery of factors essential to disease occurrence and the development of methods for disease prevention

    • E. 

      Both the discovery of factors essential to disease occurrence and measuring the level of resistance to antimicrobial agents

  • 25. 
    ____ is the site of maturation of T cells
    • A. 

      Bursa of fabricius

    • B. 

      Thymus

    • C. 

      Spleen

    • D. 

      Bone marrow

    • E. 

      Lymph nodes