Microbiology Exam V - Summer 2011

  • USMLE
  • MCAT
  • NBME
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1. Inflammation of the sac around the heart

Explanation

Pericarditis refers to the inflammation of the sac around the heart, known as the pericardium. This condition can be caused by various factors such as infections, autoimmune diseases, or injury. The inflammation of the pericardium can lead to symptoms such as chest pain, difficulty breathing, and fever. Treatment for pericarditis may involve medications to reduce inflammation and manage symptoms.

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Microbiology Exam V - Summer 2011 - Quiz

Microbiology Exam V - Summer 2011 assesses key microbiological concepts and diseases, focusing on mechanisms of transmission, pathogenic characteristics, and diagnostic criteria. It is crucial for students preparing for medical and health-related careers.

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2. Small fluid-filled lesions on the skin

Explanation

Vesicles are small fluid-filled lesions on the skin. They are often caused by viral infections such as herpes simplex virus or varicella-zoster virus. Vesicles can also be a symptom of certain autoimmune disorders or allergic reactions. They appear as small, raised, and blister-like structures on the skin, filled with clear fluid. Vesicles can be itchy or painful and may rupture, leading to the formation of crusts or scabs. Treatment for vesicles depends on the underlying cause and may include antiviral medications, topical creams, or oral medications to relieve symptoms and promote healing.

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3. Ringworm of the feet

Explanation

Tinea pedis, also known as athlete's foot, is a fungal infection that affects the feet. It is characterized by symptoms such as itching, redness, and peeling of the skin on the feet. The term "ringworm of the feet" refers to this specific condition, caused by the fungus Trichophyton rubrum. Tinea cruris refers to a fungal infection of the groin area, tinea barbae is a fungal infection of the beard area, tinea manuum refers to a fungal infection of the hands, and tinea unguium is a fungal infection of the nails.

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4. The most common cause of vaginitis is

Explanation

The most common cause of vaginitis is Candida albicans. This is because Candida albicans is a type of yeast that naturally resides in the vagina. However, when there is an overgrowth of this yeast, it can lead to an infection known as vaginal yeast infection or candidiasis. Factors such as hormonal changes, weakened immune system, antibiotic use, and poor hygiene can contribute to the overgrowth of Candida albicans. Symptoms of vaginitis caused by Candida albicans include itching, burning, and abnormal discharge. Treatment usually involves antifungal medications to eliminate the yeast overgrowth.

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5. Protozoan disease that causes irritation and profuse discharge in infected females

Explanation

Trichomonas vaginalis is a protozoan parasite that causes a sexually transmitted infection known as trichomoniasis. It primarily affects females and can cause irritation and inflammation in the genital area, leading to a profuse discharge. This infection is characterized by symptoms such as itching, burning, and discomfort during urination or sexual intercourse. Therefore, trichomonas vaginalis is the correct answer for the given description.

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6. African sleeping sickness

Explanation

Trypanosoma brucei gambiense is the correct answer because it is the causative agent of African sleeping sickness. African sleeping sickness is a parasitic disease that is transmitted to humans through the bite of infected tsetse flies. The parasite affects the central nervous system, causing symptoms such as fever, fatigue, headaches, and sleep disturbances. If left untreated, it can lead to severe neurological complications and death. Therefore, Trypanosoma brucei gambiense is the most appropriate answer among the given options.

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7. Lyme disease is transmitted by

Explanation

Lyme disease is primarily transmitted by ticks. Ticks are small arachnids that attach themselves to the skin of animals or humans and feed on their blood. When an infected tick bites a person, it can transmit the bacteria that cause Lyme disease into their bloodstream. This is why it is important to take precautions, such as wearing protective clothing and using insect repellent, when in areas where ticks are known to be prevalent.

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8. Oral lesions called Koplik's spots are seen in patients with

Explanation

Koplik's spots are small white spots that appear on the inside of the cheeks and are characteristic of measles (rubeola). They are caused by the measles virus and are typically seen a few days before the onset of the rash. Croup, mumps, influenza, and rubella do not typically present with Koplik's spots, making measles the correct answer.

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9. Thrush

Explanation

Candidiasis is a fungal infection caused by the overgrowth of Candida, a type of yeast. It can affect various parts of the body, including the mouth, throat, genitals, and skin. Common symptoms include white patches in the mouth or throat, itching and burning sensations, and vaginal discharge in women. Risk factors for candidiasis include weakened immune system, diabetes, pregnancy, and the use of certain medications like antibiotics or corticosteroids. Treatment usually involves antifungal medications, both topical and oral. Candidiasis is not caused by a parasite like Trypanosoma brucei gambiense or Naegleria fowleri, or bacteria like Meningococcal or Tetanus.

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10. What is the bacterium responsible for inflammatory acne?

Explanation

Propionibacterium acne is the correct answer for the bacterium responsible for inflammatory acne. This bacterium is commonly found on the skin and is associated with the formation of acne. It plays a role in the inflammation and infection of the hair follicles, leading to the development of inflammatory acne.

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11. Genital warts

Explanation

Papillomaviruses are responsible for causing genital warts. These viruses are transmitted through sexual contact and can lead to the development of warts on the genitals, anus, or surrounding areas. Genital warts are a common sexually transmitted infection and can vary in size and appearance. They can be flesh-colored, pink, or gray and may be raised or flat. Papillomaviruses can also cause other types of warts, such as common warts and plantar warts, which appear on the hands, fingers, feet, or toes. It is important to seek medical attention if you suspect you have genital warts, as treatment options are available.

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12. Which organism is a common cause of meningitis in AIDS patients and can be found in bird droppings?

Explanation

Cryptococcus neoformans is a common cause of meningitis in AIDS patients and can be found in bird droppings. This organism is a type of fungus that is commonly found in soil and bird droppings, particularly those of pigeons. It can be inhaled and cause infection in individuals with weakened immune systems, such as those with AIDS. Meningitis caused by Cryptococcus neoformans can be life-threatening if not treated promptly.

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13. Rocky Mountain Spotted Fever

Explanation

Rickettsia is the correct answer because Rocky Mountain Spotted Fever is a tick-borne disease caused by the bacteria Rickettsia rickettsii. Rickettsia is a genus of bacteria that are transmitted to humans through the bite of infected ticks, fleas, or lice. In the case of Rocky Mountain Spotted Fever, the bacteria is transmitted through the bite of infected ticks belonging to the Dermacentor genus. Therefore, Rickettsia is the most relevant and appropriate option among the given choices.

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14. Rocky Mountain Spotted Fever

Explanation

Rickettsia rickettsii is the correct answer because it is the causative agent of Rocky Mountain Spotted Fever, a tick-borne illness. This bacterium is transmitted to humans through the bite of infected ticks, specifically the American dog tick and the Rocky Mountain wood tick. The disease presents with symptoms such as fever, headache, rash, and in severe cases, can lead to organ damage and even death if not treated promptly. Therefore, Rickettsia rickettsii is the most appropriate answer in this context.

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15. Meningitis is caused by the bacterium Neisseria meningitidis

Explanation

Meningococcal refers to the bacterium Neisseria meningitidis, which is known to cause meningitis. Meningitis is an inflammation of the membranes surrounding the brain and spinal cord, and it can be caused by various pathogens including bacteria, viruses, and fungi. In this case, the correct answer suggests that the specific bacterium Neisseria meningitidis is responsible for causing meningitis.

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16. Blood is a mixture of all of the following

Explanation

Blood is a mixture of plasma, red blood cells (RBCs), and white blood cells (WBCs). Plasma is the liquid component of blood that carries nutrients, hormones, and waste products. RBCs, also known as erythrocytes, are responsible for carrying oxygen to the body's tissues. WBCs, or leukocytes, play a crucial role in the immune system by defending the body against infections and foreign substances. Therefore, the correct answer is A, B, and C, as all of these components are present in blood.

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17. Neurotoxin that blocks the nerve pathway that signals muscle relaxation (clostridium tetani)

Explanation

Tetanospasmin is a neurotoxin produced by the bacteria Clostridium tetani. It works by blocking the nerve pathway that signals muscle relaxation, leading to sustained muscle contractions and spasms. This causes the condition known as tetanus.

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18. A diagnosis of tuberculosis involves

Explanation

The correct answer is "All of the choices are correct" because a diagnosis of tuberculosis typically involves multiple tests and examinations. A chest X-ray is commonly used to detect abnormalities in the lungs that may indicate tuberculosis. Acid-fast stain of sputum is performed to identify the presence of Mycobacterium tuberculosis, the bacteria that causes tuberculosis. Sputum culture is used to confirm the presence of the bacteria and determine its drug susceptibility. The tuberculin skin test is used to assess a person's immune response to tuberculosis. Therefore, all of these choices are correct when it comes to diagnosing tuberculosis.

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19. One virulence factor of Mycobacterium leprae is the ability to live inside

Explanation

Mycobacterium leprae, the bacterium that causes leprosy, has the ability to live inside macrophages. Macrophages are immune cells that play a crucial role in engulfing and destroying pathogens. However, Mycobacterium leprae can evade the immune system by residing within macrophages, allowing it to persist and cause infection. This ability to survive inside macrophages is a significant virulence factor of the bacterium, as it enables it to evade immune responses and establish a chronic infection.

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20. Growth of bacteria in the blood

Explanation

Septicemia refers to a serious bloodstream infection caused by bacteria. The growth of bacteria in the blood can lead to septicemia, which is a life-threatening condition if left untreated. It occurs when bacteria from an infection in another part of the body enter the bloodstream and spread throughout the body. This can cause a systemic inflammatory response, leading to symptoms such as fever, rapid heart rate, low blood pressure, and organ dysfunction. Prompt medical intervention, including antibiotics and supportive care, is crucial in treating septicemia and preventing complications.

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21. Grave's disease is an immune reaction against the thyroid gland receptor sites that causes excessive production of thyroid hormones.

Explanation

Grave's disease is an autoimmune disorder in which the body's immune system mistakenly attacks the thyroid gland. This immune reaction leads to the overstimulation of the thyroid gland, causing it to produce excessive amounts of thyroid hormones. Therefore, the statement that Grave's disease is an immune reaction against the thyroid gland receptor sites that causes excessive production of thyroid hormones is true.

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22. The causative agent of the bubonic plague is

Explanation

Yersinia pestis is the correct answer because it is the bacterium responsible for causing the bubonic plague. This bacterium is primarily transmitted through fleas that infest rats and other small mammals. When a flea bites an infected animal, it can then transmit the bacteria to humans. The bubonic plague is a severe and potentially deadly disease that causes symptoms such as fever, chills, swollen lymph nodes, and ultimately, if left untreated, can lead to organ failure and death.

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23. A fungal infection of the body

Explanation

Mycosis refers to a fungal infection of the body. It is a general term used to describe any infection caused by fungi, which can affect various parts of the body such as the skin, nails, or internal organs. Fungal infections are common and can be caused by different types of fungi, including yeasts and molds. Treatment for mycosis usually involves antifungal medications to eliminate the infection and relieve symptoms.

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24. Disease caused by the bite of the anopheles mosquito

Explanation

Malaria is a disease caused by the bite of the Anopheles mosquito. The mosquito carries a parasite called Plasmodium, which is transmitted to humans through its bite. Once inside the human body, the parasite multiplies and infects the red blood cells, causing symptoms such as fever, chills, and flu-like illness. Malaria is a significant global health problem, particularly in tropical and subtropical regions. It can be prevented through the use of mosquito nets, insect repellents, and antimalarial medications.

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25. Cells that may ingest tuberculosis bacilli

Explanation

Alveolar macrophages are cells found in the lungs that have the ability to ingest and eliminate foreign particles, including tuberculosis bacilli. These macrophages play a crucial role in the immune response against tuberculosis infection by engulfing and destroying the bacteria. Therefore, alveolar macrophages are the cells that may ingest tuberculosis bacilli.

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26. The oily secretion that lubricates the hair follicles of the skin is

Explanation

Sebum is the oily secretion produced by the sebaceous glands in the skin. It lubricates the hair follicles, keeping them moisturized and preventing them from becoming dry and brittle. Sebum also helps to protect the skin by forming a barrier against bacteria and other harmful substances. Eczema, suder, and acne are not related to the lubrication of hair follicles.

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27. Pathogen grows at refrigerator temperatures

Explanation

Listeria monocytogenes is the correct answer because it is a pathogen that is known to grow at refrigerator temperatures. Unlike most bacteria that cannot grow in cold temperatures, Listeria monocytogenes can thrive and multiply in refrigerated environments, making it a significant concern for food safety. This ability to grow at low temperatures increases the risk of contamination and foodborne illnesses associated with Listeria monocytogenes.

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28. Which of the following provides the eye with its best defense against microorganisms?

Explanation

Tears provide the eye with its best defense against microorganisms because they contain lysozyme, an enzyme that has antibacterial properties. When tears are produced, they help to wash away any foreign particles or microorganisms that may come into contact with the eye, preventing infection. Additionally, tears also contain other immune components such as antibodies and antimicrobial proteins that further enhance the eye's defense against microorganisms.

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29. Whooping cough

Explanation

Bordetella pertussis is the correct answer because it is the causative agent of whooping cough, a highly contagious respiratory infection. The other options, such as ghon complexes, listeria monocytogenes, schistosoma spp., and neuraminidase, are not associated with whooping cough.

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30. Which of the following methods can be used as a diagnosis of syphilis?

Explanation

All of the above methods can be used for the diagnosis of syphilis. Direct microscopic ID involves examining samples under a microscope to detect the presence of the bacteria causing syphilis. Staining with FA (fluorescent antibody) is a technique that uses fluorescently labeled antibodies to identify specific antigens, such as those found in syphilis bacteria. ELISA (enzyme-linked immunosorbent assay) is a blood test that detects antibodies produced by the body in response to syphilis infection. Therefore, all three methods can be used to diagnose syphilis.

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31. Trypanosoma cruzi is the causative agent of

Explanation

Trypanosoma cruzi is a parasitic protozoan that causes Chaga's disease, also known as American trypanosomiasis. This disease is primarily found in Central and South America and is transmitted to humans through the bite of infected triatomine bugs, also known as "kissing bugs." Chaga's disease can cause a range of symptoms, including fever, fatigue, body aches, and swollen lymph nodes. If left untreated, it can lead to serious complications, such as heart and digestive system damage. Therefore, the correct answer is Chaga's disease.

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32. Ringworm of the beard

Explanation

Tinea barbae is a fungal infection that affects the beard area. It is caused by dermatophytes, which are a type of fungi. The infection can cause redness, itching, and scaling of the affected area. Tinea barbae is more common in men and can be spread through direct contact with an infected person or by using contaminated objects such as towels or razors. Treatment usually involves antifungal medications, both topical and oral, to eliminate the infection.

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33. The most immediate and important treatment needed to prevent death in cholera victims is

Explanation

The most immediate and important treatment needed to prevent death in cholera victims is water and electrolyte replacement. Cholera is a severe diarrheal disease that causes rapid dehydration and electrolyte imbalances. Replenishing fluids and electrolytes is crucial in preventing death from dehydration and maintaining proper bodily functions. Antimicrobials may be used to treat the underlying infection, but the immediate priority is restoring the body's fluid balance. Antitoxin and surgery are not relevant in the treatment of cholera.

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34. T cells attack the myelin sheath of the nervous system

Explanation

Multiple sclerosis is an autoimmune disease in which the immune system mistakenly attacks the protective covering of nerve fibers, known as the myelin sheath, in the central nervous system. This leads to disruption in the transmission of nerve signals, causing a range of symptoms such as fatigue, difficulty in coordination, and problems with speech and vision. Streptomyces is a type of bacteria, septicemia refers to a bloodstream infection, and saxitoxin is a potent neurotoxin, none of which are directly related to the attack on the myelin sheath seen in multiple sclerosis.

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35. German measles is caused by

Explanation

German measles, also known as rubella, is caused by the rubella virus. Rubella is a highly contagious viral infection that is spread through respiratory droplets. It primarily affects children and young adults, causing a rash, fever, and swollen lymph nodes. Rubella can be particularly dangerous for pregnant women, as it can lead to severe birth defects in the developing fetus. The other options listed, such as rubeola virus, herpes virus, HIV virus, and papillomavirus, do not cause German measles.

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36. Sheep liver fluke

Explanation

The correct answer is "fasciola hepatica" because it is the only option that matches the given term "sheep liver fluke". Clonorchis sinensis is a type of liver fluke that infects humans and other animals, not specifically sheep. Schistoma spp. refers to a group of parasitic worms that cause schistosomiasis, a different type of infection. "None of the above" is not applicable as there is a correct answer provided.

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37. Gp120 binds to

Explanation

gp120 is a glycoprotein found on the surface of HIV virus that is responsible for binding to the CD4 receptor on the surface of T-helper cells. This binding is crucial for the virus to enter the host cell and initiate the infection. Therefore, the correct answer is CD4.

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38. The normal biota of the CNS consists of

Explanation

The central nervous system (CNS) is a highly protected and sterile environment, which means that it does not have a normal biota. This is because the CNS is enclosed within the skull and spinal column, and is surrounded by protective barriers such as the blood-brain barrier. These barriers prevent the entry of microorganisms into the CNS, thereby maintaining its sterility. Therefore, the statement that the CNS has no normal biota is correct.

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39. __________ occurs when bacteria flourish and grow in the blood stream.

Explanation

Septicemia occurs when bacteria flourish and grow in the bloodstream. This condition is characterized by the presence of bacteria in the blood, leading to a systemic infection. It is a severe and potentially life-threatening condition that can result in organ failure and septic shock. Prompt medical intervention is crucial to treat septicemia and prevent further complications.

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40. All of the following pertain to patients with AIDS except

Explanation

Patients with AIDS can have an immunodeficiency, CD4 T-cell titers below 200 cells/mm3 of blood, repeated, life-threatening opportunistic infections, and can develop unusual cancers and neurological disorders. However, the statement that the highest number of cases worldwide is in the United States is not true. This statement is incorrect because the highest number of AIDS cases worldwide is actually in sub-Saharan Africa.

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41. Infection of the dermal layer of the skin by streptococcus pyogenes

Explanation

Erysipelas is a bacterial infection caused by Streptococcus pyogenes that affects the dermal layer of the skin. It is characterized by redness, swelling, and pain in the affected area. This explanation provides a clear and concise description of erysipelas and its association with the given correct answer.

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42. Shingles

Explanation

The correct answer is herpes viruses. Shingles, also known as herpes zoster, is caused by the reactivation of the varicella-zoster virus, which is a type of herpes virus. This virus is responsible for both chickenpox and shingles. Shingles is characterized by a painful rash that usually appears on one side of the body. It is important to note that while shingles is caused by a herpes virus, it is not the same as genital herpes or cold sores, which are caused by different types of herpes viruses.

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43. Ringworm

Explanation

Tinea is a fungal infection of the skin, commonly known as ringworm. It is caused by various species of fungi, including Trichophyton, Microsporum, and Epidermophyton. Tinea can affect different parts of the body, such as the scalp, body, feet, and nails. It is characterized by a red, itchy rash that may have a ring-shaped appearance. Treatment typically involves antifungal medications, both topical and oral, to eliminate the infection. Tinea is not caused by any of the other mentioned parasites or worms, making it the correct answer.

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44. "Rice water stools" are associated with disease caused by this organism

Explanation

"Rice water stools" are a characteristic symptom of cholera, a disease caused by Vibrio cholerae. Cholera is an acute diarrheal illness that results in the production of large amounts of watery stools that resemble rice water in appearance. Vibrio cholerae is a bacterium that infects the small intestine and produces a toxin that leads to the excessive secretion of water and electrolytes, resulting in the characteristic rice water stools.

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45. Impetigo is caused by

Explanation

Impetigo is a highly contagious skin infection that is commonly caused by both Staphylococcus aureus and Streptococcus pyogenes. These bacteria can enter the body through cuts, abrasions, or insect bites, leading to the development of small blisters or sores on the skin. The infection spreads easily through direct contact with the affected person or contaminated objects. Both Staphylococcus aureus and Streptococcus pyogenes produce toxins that contribute to the characteristic symptoms of impetigo, such as redness, itching, and the formation of a yellowish crust. Treatment typically involves topical or oral antibiotics to eliminate the bacterial infection.

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46. Which of the following is a sexually transmitted disease?

Explanation

Trichomoniasis is a sexually transmitted disease caused by a parasite called Trichomonas vaginalis. It is mainly transmitted through sexual contact, including vaginal, anal, or oral sex. Symptoms of trichomoniasis include itching, burning, and discharge in the genital area. It can be easily treated with antibiotics. Toxoplasmosis, giardiasis, malaria, and balantidiasis are not sexually transmitted diseases. Toxoplasmosis is caused by a parasite found in cat feces, giardiasis is caused by a parasite found in contaminated food or water, malaria is caused by a parasite transmitted through mosquito bites, and balantidiasis is caused by a parasite found in contaminated food or water.

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47. The fibrous sac that encloses the heart is the

Explanation

The fibrous sac that encloses the heart is called the pericardium. The pericardium is a double-layered membrane that surrounds the heart and provides protection and support. It consists of an outer fibrous layer and an inner serous layer. The fibrous layer is tough and dense, while the serous layer is smooth and lubricated, allowing the heart to beat and move within the pericardial sac without friction. The pericardium also helps to prevent the heart from overfilling with blood and helps maintain its position within the chest cavity.

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48. Ringworm

Explanation

Tinea is the correct answer because it is a common fungal infection of the skin, hair, or nails. It is also known as ringworm, which causes red, scaly patches that may itch or cause a burning sensation. The other options, Macules, Rickettsia rickettsii, Borrelia burgdorferi, and Pericarditis, are unrelated to ringworm and do not fit the description of the given term.

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49. The main causative agent of gas gangrene is

Explanation

Clostridium perfringens is the correct answer for the main causative agent of gas gangrene. Gas gangrene is a severe and potentially life-threatening infection that occurs when the bacteria Clostridium perfringens invades deep muscle tissue. This bacterium is commonly found in soil and can enter the body through open wounds, surgical sites, or deep puncture wounds. Once inside the body, it produces toxins that destroy tissue and cause the characteristic symptoms of gas gangrene, including severe pain, swelling, and the production of gas bubbles in the affected area. Prompt medical treatment is necessary to prevent the spread of infection and potential complications.

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50. Shiga toxin

Explanation

Shigella is the correct answer because it is the only option that is directly related to the term "Shiga toxin". Shiga toxin is a type of toxin produced by certain strains of the Shigella bacteria. Streptococcus mutans is a bacteria associated with dental caries, Cryptosporidium parvum is a parasite causing gastrointestinal illness, and Entamoeba histolytica is a parasite causing amoebic dysentery. Vesicles, on the other hand, are small fluid-filled sacs that can be found in various parts of the body and are not directly related to Shiga toxin or any of the other options.

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51. Helicobacter pylori appears to have some connection with

Explanation

Helicobacter pylori is a type of bacteria that is commonly found in the stomach. It is known to cause ulcers by damaging the lining of the stomach or small intestine. Additionally, it has been linked to an increased risk of stomach cancer. Therefore, the correct answer is ulcers AND stomach cancer, indicating that Helicobacter pylori is associated with both conditions.

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52. Carries Malaria

Explanation

Anopheles is the correct answer because it is the primary carrier of malaria. Malaria is a mosquito-borne infectious disease caused by the Plasmodium parasite, which is transmitted to humans through the bite of infected female Anopheles mosquitoes. These mosquitoes are specifically adapted to transmit the disease and are found in many parts of the world, particularly in tropical and subtropical regions. Therefore, Anopheles is the most relevant option among the given choices as it directly relates to the transmission of malaria.

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53. Infections caused by obligate anaerobes such as clostridium perfringens are sometimes treated by putting the patients in ______ chambers.

Explanation

Infections caused by obligate anaerobes such as Clostridium perfringens are sometimes treated by putting the patients in hyperbaric chambers. Hyperbaric chambers are pressurized chambers that allow patients to breathe in 100% oxygen at higher than normal atmospheric pressure. This high-pressure environment helps to increase the amount of oxygen dissolved in the blood, which can inhibit the growth of anaerobic bacteria like Clostridium perfringens. By exposing the infection to high levels of oxygen, hyperbaric therapy can help to kill the bacteria and promote healing.

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54. Neurotoxin produced by dinoflagellates

Explanation

Saxitoxin is a neurotoxin produced by dinoflagellates. It is a potent toxin that can cause paralytic shellfish poisoning in humans. It blocks the channels responsible for the movement of sodium ions in nerve cells, leading to muscle paralysis and potentially respiratory failure. This toxin is commonly found in shellfish, such as clams and mussels, that have consumed dinoflagellates. It is important to avoid consuming shellfish from areas where saxitoxin contamination is suspected to prevent poisoning.

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55. Blood flukes

Explanation

Schistosoma spp. refers to a group of parasitic blood flukes that infect humans. These flukes cause a disease called schistosomiasis, which is a major public health problem in many developing countries. The other options listed are not related to schistosoma spp. For example, bordetella pertussis causes whooping cough, ghon complexes are associated with tuberculosis, listeria monocytogenes causes listeriosis, and neuraminidase is an enzyme produced by influenza viruses. Therefore, schistosoma spp. is the correct answer in this context.

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56. Syphilis

Explanation

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57. Diphtheria

Explanation

Corynebacterium is the correct answer because it is a genus of bacteria that includes the species Corynebacterium diphtheriae, which causes diphtheria. The other options, malaria, puerperal sepsis, alveolar macrophages, and trichomonas vaginalis, are not related to Corynebacterium or diphtheria.

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58. The toxin of Staphylococcus aureus strains that causes blisters and desquamation of skin in scalded skin syndrome is

Explanation

The correct answer is exfoliative toxin. Exfoliative toxin is produced by certain strains of Staphylococcus aureus and is responsible for causing blisters and desquamation of the skin in scalded skin syndrome. This toxin acts by causing the separation of the epidermis from the underlying dermis, leading to the characteristic symptoms of the disease. Enterotoxin is responsible for causing food poisoning, hemolysin causes destruction of red blood cells, toxic shock syndrome toxin causes toxic shock syndrome, and erythrogenic toxin is responsible for the rash seen in scarlet fever.

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59. Candida albicans is a

Explanation

Candida albicans is a fungus. Fungi are a group of organisms that include yeasts, molds, and mushrooms. Candida albicans is a type of yeast that is commonly found in the human body, particularly in the mouth, throat, and genital area. It can cause infections, such as oral thrush and vaginal yeast infections, especially in individuals with weakened immune systems. Therefore, the correct answer is fungus.

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60. The loss of blood supply to tissue is referred to as

Explanation

Ischemia refers to the loss of blood supply to tissue. This can occur due to various reasons such as blockage of blood vessels or reduced blood flow. When tissue is deprived of oxygen and nutrients, it can lead to tissue damage and cell death. Necrosis is the death of cells or tissues, which can occur as a result of ischemia. Gangrene is a type of necrosis that is characterized by tissue death and decay. Inflammation, on the other hand, is the body's response to injury or infection and is not specifically related to the loss of blood supply. Therefore, the correct answer is ischemia.

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61. Cause of many dental caries

Explanation

Streptococcus mutans is a bacterium commonly found in the oral cavity and is a major contributor to the development of dental caries. It produces acids as a byproduct of metabolizing sugars, which leads to the demineralization of tooth enamel and the formation of cavities. This bacterium thrives in an acidic environment and is able to adhere to the tooth surface, forming biofilms known as dental plaque. The presence of Streptococcus mutans in the oral cavity, along with poor oral hygiene and excessive sugar consumption, increases the risk of developing dental caries.

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62. This freshwater amoeba used to be associated with unsanitary contact lenses, ausing tremendous corneal damage.

Explanation

Acanthamoeba keratitis is a type of eye infection caused by the amoeba Acanthamoeba. It is commonly associated with unsanitary contact lenses, as the amoeba can thrive in the stagnant water that accumulates on the lenses. This infection can cause severe damage to the cornea, leading to vision impairment or even blindness if left untreated. Therefore, the given answer correctly identifies the freshwater amoeba that is associated with unsanitary contact lenses and causes corneal damage.

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63. This disease is a result of an autoimmune complication of repeat Streptococcus pyogenes infections

Explanation

Rheumatic fever is the correct answer because it is a disease that occurs as a result of an autoimmune complication of repeat Streptococcus pyogenes infections. This means that when a person has multiple infections caused by Streptococcus pyogenes, their immune system mistakenly attacks their own body tissues, leading to the development of rheumatic fever. This condition primarily affects the heart, joints, skin, and brain, causing symptoms such as fever, joint pain, rash, and neurological problems.

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64. This protozoan parasite is found in healthy human lungs, waiting for a chance to infect the host when the host is immunocompromised.

Explanation

Pneumocystis is a protozoan parasite that can be found in healthy human lungs. It remains dormant in the lungs until the host's immune system becomes compromised, providing an opportunity for the parasite to infect the host. This can occur in individuals with weakened immune systems, such as those with HIV/AIDS or undergoing immunosuppressive therapy. Pneumocystis pneumonia is a common opportunistic infection in these individuals.

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65. Which of the following is not true of bacterial conjunctivitis?

Explanation

Bacterial conjunctivitis is characterized by symptoms such as redness, swelling, and discharge from the eyes. The discharge is typically thick and yellow or green in color, not clear. Therefore, the statement "Has a clear discharge" is not true of bacterial conjunctivitis.

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66. Flat reddened lesions

Explanation

Macules are flat, reddened lesions on the skin. They are small, distinct, and do not have any elevation or palpable changes in texture. Macules can be caused by various conditions such as viral infections, allergic reactions, or inflammatory skin diseases. They are different from other skin lesions like papules or plaques, which have different characteristics. In this case, the presence of flat reddened lesions suggests macules as the correct answer.

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67. Bacterial meningitis is caused by all of the following except

Explanation

Bacterial meningitis is an infection of the membranes surrounding the brain and spinal cord. It is commonly caused by bacteria such as Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. However, Naegleria fowleri is not a bacterium but a free-living amoeba found in warm freshwater environments. It can cause a rare and severe form of meningitis called primary amoebic meningoencephalitis (PAM), but it is not classified as bacterial meningitis. Therefore, Naegleria fowleri is the exception among the given options.

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68. This soil fungus, associated with pigeon and chicken droppings, can cause a form of meningitis, that has a 30% mortality rate.

Explanation

Cryptococcus neoformans is a soil fungus commonly found in pigeon and chicken droppings. When inhaled, it can cause a form of meningitis in humans. This infection has a mortality rate of approximately 30%. Therefore, Cryptococcus neoformans is the correct answer as it matches the description provided in the question.

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69. Ringworm of the groin

Explanation

Tinea cruris, also known as ringworm of the groin, is the correct answer. It is a fungal infection that affects the groin area and is commonly referred to as jock itch. This infection is characterized by a red, itchy rash in the groin region, which can spread to the inner thighs and buttocks. Tinea cruris is caused by the same type of fungus that causes athlete's foot, known as dermatophytes. It is often seen in individuals who sweat excessively or wear tight clothing, as these conditions create a warm and moist environment that promotes fungal growth.

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70. What material in skin cells provides protection from abrasions, water damage and microorganism entry?

Explanation

Keratin is a protein found in the outermost layer of the skin, known as the epidermis. It forms a tough, waterproof barrier that protects the skin from abrasions, water damage, and the entry of microorganisms. Keratin also helps to maintain the structural integrity of the skin and prevents it from drying out. This makes it an essential component in providing overall protection to the skin.

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71. Which is incorrect about warts?

Explanation

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72. Blood fluke

Explanation

Schistosoma is the correct answer because it is a type of blood fluke that causes schistosomiasis, a parasitic disease. Schistosoma parasites infect humans when they come into contact with contaminated freshwater, such as rivers or lakes. The parasites penetrate the skin and migrate to the blood vessels around the intestines or bladder, causing various symptoms including fever, abdominal pain, and blood in urine or stool. Schistosomiasis is a significant public health problem in many tropical and subtropical regions, affecting millions of people worldwide. Therefore, Schistosoma is the most appropriate answer among the given options.

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73. Valuable source of many commercial antibiotics

Explanation

Streptomyces is a valuable source of many commercial antibiotics. Streptomyces is a genus of bacteria that produces a wide range of antibiotics, including streptomycin, tetracycline, and erythromycin. These antibiotics are commonly used to treat various bacterial infections in humans and animals. Streptomyces bacteria are known for their ability to produce secondary metabolites, including antibiotics, which makes them an important resource in the pharmaceutical industry. Therefore, streptomyces is the correct answer as it is a valuable source of many commercial antibiotics.

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74. This virus, transmitted by an animal bite, multiplies in skeletal muscles and then in brain cells, eventually causes encephalitis

Explanation

The correct answer is rabies virus because it is a virus that is transmitted through animal bites, particularly from infected dogs, bats, and other mammals. Once it enters the body, the virus multiplies in the skeletal muscles before spreading to the brain cells. This leads to inflammation of the brain, known as encephalitis, which is a characteristic symptom of rabies infection.

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75. This arthropod vector is responsible for carrying the causative agent of Lyme disease

Explanation

Ixodes is the correct answer because it is a genus of arthropod vectors that are known to carry the causative agent of Lyme disease. Lyme disease is caused by the bacterium Borrelia burgdorferi, which is transmitted to humans through the bite of infected ticks. Ixodes ticks are commonly found in wooded and grassy areas, and they are known to transmit the bacteria to humans during feeding. Therefore, Ixodes is responsible for carrying the causative agent of Lyme disease.

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76. Reactivation of chickenpox is called

Explanation

Shingles is the correct answer because it refers to the reactivation of the chickenpox virus, also known as herpes zoster. Shingles is characterized by a painful rash that typically appears in a band or strip on one side of the body. While pneumonia is a respiratory infection and exanthems are a general term for rash or skin eruptions, they are not specific to the reactivation of chickenpox. Therefore, shingles is the most accurate term for the reactivation of chickenpox.

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77. Symptoms of cryptosporidiosis include

Explanation

The correct answer is "Symptoms of cryptosporidiosis include headache, sweats, vomiting, severe abdominal cramps, and diarrhea." This answer accurately describes the symptoms commonly associated with cryptosporidiosis, which is an infection caused by the parasite Cryptosporidium. These symptoms are consistent with the gastrointestinal symptoms typically experienced by individuals with this infection.

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78. American dog tick

Explanation

Dermacentor is the correct answer because it is the only option that is a type of tick. The other options, Rickettsia, Schistosoma, and Anapheles, are not ticks but rather refer to different organisms or diseases. Therefore, Dermacentor is the most appropriate choice in this context.

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79. The serotype of influenza that causes most epidemics is serotype

Explanation

The serotype of influenza that causes most epidemics is serotype A. Influenza A viruses are known to infect humans, birds, and other animals, and they have the ability to undergo genetic changes through a process called antigenic shift. This allows them to easily adapt and spread among different populations, leading to widespread epidemics. In contrast, serotype B and serotype C influenza viruses generally cause milder illness and do not undergo antigenic shift as frequently as serotype A viruses. Serotype A influenza viruses are therefore considered the most significant in terms of causing epidemics.

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80. Which of the following genera is responsible for causing gonorrhea?

Explanation

Neisseria is the correct answer because it is the genus responsible for causing gonorrhea. Gonorrhea is a sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae. This bacterium is transmitted through sexual contact and can affect both men and women. It primarily infects the genital tract, but can also infect the rectum, throat, and eyes. Neisseria gonorrhoeae can cause symptoms such as pain during urination, discharge from the genitals, and in women, pelvic pain and abnormal vaginal bleeding. If left untreated, gonorrhea can lead to serious complications such as infertility and increased risk of HIV infection.

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81. All of the following are pre-disposing factors that contribute to haemophilus influenzae pneumonia except

Explanation

The given correct answer is "all of the following are pre-disposing factors." This means that none of the options listed (alcoholism, poor nutrition, cancer, diabetes) contribute to haemophilus influenzae pneumonia as pre-disposing factors. In other words, none of these conditions increase the likelihood of developing this type of pneumonia.

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82. Necator and ancylostoma are both human

Explanation

Necator and Ancylostoma are both types of hookworms. Hookworms are parasitic worms that infect the intestines of humans. They attach themselves to the intestinal wall and feed on blood, causing anemia and other symptoms. These worms are commonly found in areas with poor sanitation and can be acquired by walking barefoot on contaminated soil. Therefore, the correct answer is hookworms.

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83. MRSAs are S. aureus strains that are

Explanation

MRSAs, or Methicillin-resistant Staphylococcus aureus, are strains of S. aureus bacteria that have developed resistance to penicillin derivatives. This means that they are not affected by the antibiotics that are commonly used to treat infections caused by S. aureus, such as methicillin and other penicillin-based drugs. This resistance is a result of genetic changes in the bacteria that allow them to produce enzymes called beta-lactamases, which break down the antibiotics and render them ineffective. As a result, MRSAs are difficult to treat and can cause severe infections that are resistant to many commonly used antibiotics.

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84. Permanent cardiovascular and neurological damage is seen in which stage of syphilis?

Explanation

In the tertiary stage of syphilis, permanent cardiovascular and neurological damage is seen. This stage occurs when the infection is left untreated for a long time, usually several years after the initial infection. The bacteria have spread throughout the body, causing damage to various organs, including the heart and the nervous system. This can lead to serious complications such as heart disease, stroke, and neurosyphilis, which can result in paralysis, blindness, and dementia. Treatment at this stage can help manage the symptoms but may not reverse the permanent damage already done.

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85. About 60% of the bacterial pneumonias that require hospitalization of adults are caused by

Explanation

S. pneumoniae is the correct answer because it is known to be a common cause of bacterial pneumonia in adults requiring hospitalization. It is a pathogenic bacterium that can infect the lungs and lead to pneumonia. The other options, S. pyogenes, S. aureus, and K. pneumonia, are also potential causes of pneumonia, but they are not as commonly associated with hospitalization in adults as S. pneumoniae.

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86. What brain defense restricts substances from entering the brain by the vascular system?

Explanation

The blood-brain barrier is a protective mechanism in the brain that restricts the entry of substances from the vascular system. It is composed of specialized cells that line the blood vessels in the brain, forming a barrier that prevents the passage of harmful substances, toxins, and large molecules into the brain tissue. This barrier plays a crucial role in maintaining the delicate balance of the brain's internal environment and protecting it from potential damage.

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87. The major agents responsible for the common cold are

Explanation

Rhinoviruses are the major agents responsible for the common cold. They are a type of virus that infects the upper respiratory tract, causing symptoms such as a runny or stuffy nose, sore throat, cough, and sneezing. Rhinoviruses are highly contagious and can spread easily from person to person through respiratory droplets. They are most active during the colder months, which is why the common cold is more prevalent during winter. While other viruses like Coxsackie, Influenza, Caliciviruses, and Rotavirus can also cause respiratory illnesses, Rhinoviruses are the most common culprits for the common cold.

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88. Koplick's spots on the oral mucosa are a useful diagnosis for the

Explanation

Koplick's spots are small red spots with blue-white centers that appear on the oral mucosa. They are a characteristic symptom of measles, which is caused by the Rubeola virus. This virus primarily affects the respiratory system and is highly contagious. The presence of Koplick's spots can help in the diagnosis of measles and differentiate it from other viral infections.

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89. Blood fluke

Explanation

The correct answer is schistoma spp. Schistosoma spp. are a type of blood fluke that infect humans and other mammals. They are responsible for causing the disease schistosomiasis, which is a major public health concern in many parts of the world. Clonorchis sinensis and Fasciola hepatica are also blood flukes, but they are not classified as Schistosoma spp. Therefore, the correct answer is schistoma spp.

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90. Which of the following is not true of Ebola and Marburg?

Explanation

Ebola and Marburg are both caused by filoviruses and can disrupt clotting factors in the body. They are transmitted through direct contact with body fluids, such as blood, saliva, and vomit. However, they are not transmitted by mosquitoes. Mosquitoes are not known to be vectors for the transmission of these viruses. Therefore, the statement that they are transmitted by mosquitoes is not true. It is important to note that there is currently no specific treatment for Ebola and Marburg, only supportive care to manage symptoms and prevent complications.

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91. Primary atypical walking pneumonia is caused by

Explanation

Primary atypical walking pneumonia is caused by Mycoplasma pneumoniae. Mycoplasma pneumoniae is a type of bacteria that commonly causes respiratory infections, particularly in young adults. It is referred to as "atypical" because the symptoms and presentation of the infection are different from those caused by typical bacteria like Streptococcus pneumoniae or Haemophilus influenzae. Mycoplasma pneumoniae infections often present with a gradual onset of symptoms, such as a persistent cough, sore throat, and fatigue. Treatment usually involves antibiotics that target Mycoplasma pneumoniae specifically.

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92. Gram-positive sepsis is caused by all of the following except

Explanation

Gram-positive sepsis is caused by various bacteria, including Staphylococci, Streptococci, and Enterococci. However, Micrococci are not typically associated with causing sepsis. Therefore, the correct answer is Micrococci.

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93. The fecal-oral cycle can be broken by all of the following methods except

Explanation

Proper antibiotic use cannot break the fecal-oral cycle. Antibiotics are used to treat bacterial infections, but they do not prevent the spread of fecal-oral diseases. The other methods mentioned, such as proper food preparation and storage, proper sewage disposal, and disinfection of drinking water, can help break the fecal-oral cycle by preventing the transmission of pathogens from feces to the mouth.

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94. Production of enterotoxin is a characteristic of

Explanation

Clostridium difficile is a bacterium that is known to produce enterotoxin. Enterotoxins are toxins that affect the intestines and cause symptoms such as diarrhea and abdominal pain. Clostridium difficile is a common cause of healthcare-associated infections, particularly in individuals who have been treated with antibiotics. It is responsible for a condition called Clostridium difficile infection (CDI), which can range from mild diarrhea to severe inflammation of the colon. Therefore, the production of enterotoxin is a characteristic of Clostridium difficile.

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95. Which of the following diseases is NOT a staphylococcal skin infection?

Explanation

Erysipelas is a bacterial skin infection caused by Streptococcus bacteria, not Staphylococcus. The other options listed are all staphylococcal skin infections caused by different strains of Staphylococcus bacteria. Erysipelas typically presents as a red, swollen, and painful rash on the skin, often accompanied by fever and chills.

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96. All of the following microorganisms exist in large numbers in the large intestine except

Explanation

Yersinia is the correct answer because it is not typically found in large numbers in the large intestine. Bacteriodes, Klebsiella, and Lactobacillus are all commonly present in the large intestine, but Yersinia is not a normal resident of this area.

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97. Anthrax is

Explanation

Anthrax is a zoonosis, meaning it can be transmitted from animals to humans. It can be transmitted through contact, inhalation, and ingestion, making it a highly contagious disease. In humans, anthrax can cause a rapidly fatal toxemia and septicemia, leading to severe illness and potentially death. Although anthrax is not commonly seen in the United States, sporadic cases can still occur. Therefore, all of the choices provided are correct explanations of anthrax.

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98. Pork tapeworm

Explanation

Taena solium, also known as the pork tapeworm, is a parasitic worm that infects humans through the consumption of undercooked pork. It is a common cause of tapeworm infections in humans and can lead to symptoms such as abdominal pain, nausea, and weight loss. The other options listed are different types of parasites but are not specifically associated with pork tapeworm infections.

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99. Production of a neurotoxin that binds to target sites on spinal cord neurons responsible for inhibiting skeletal muscle contraction is a characteristic of

Explanation

Clostridium tetani produces a neurotoxin that binds to target sites on spinal cord neurons responsible for inhibiting skeletal muscle contraction. This neurotoxin, called tetanospasmin, blocks the release of inhibitory neurotransmitters, leading to uncontrolled muscle contractions and the development of tetanus. The other options, Clostridium botulinum, Clostridium perfringens, and Clostridium difficile, do not produce this specific neurotoxin and are associated with different diseases or conditions. Therefore, the correct answer is Clostridium tetani.

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100. Retroviruses have the following characteristics except

Explanation

Retroviruses have RNA as their genetic material, not DNA. They use an enzyme called reverse transcriptase to convert their RNA into DNA, which is then integrated into the host genome. Therefore, the statement "DNA protein" is incorrect as it does not accurately describe the characteristics of retroviruses.

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101. A frequent cancer that is seen in AIDS patients is

Explanation

Kaposi's sarcoma is a frequent cancer observed in AIDS patients. It is caused by a virus called human herpesvirus 8 (HHV-8), which is more prevalent in individuals with weakened immune systems, such as those with AIDS. Kaposi's sarcoma usually manifests as purple or red lesions on the skin, but it can also affect other organs like the lungs, liver, and gastrointestinal tract. The virus is transmitted through saliva, sexual contact, and blood transfusions. Treatment options include antiretroviral therapy to boost the immune system, chemotherapy, and radiation therapy.

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102. Type of spike used by influenza virus to release virus from cells

Explanation

Neuraminidase is the correct answer because it is an enzyme found on the surface of the influenza virus. It plays a crucial role in the release of newly formed virus particles from infected cells. Neuraminidase cleaves the sialic acid receptors on the surface of host cells, allowing the virus to detach and spread to other cells. This process is essential for the influenza virus to efficiently infect and replicate within the host.

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103. Human roundworm

Explanation

Ascaris is the correct answer because it is a type of human roundworm. It is a common intestinal parasite that infects humans through contaminated food or water. Ascaris infections can cause a range of symptoms including abdominal pain, diarrhea, and malnutrition. It is important to treat and prevent Ascaris infections to avoid complications and improve overall health.

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104. Burrows in the skin to lay eggs that sets up intense, itchy inflammation

Explanation

Sarcoptes scabiei is a parasitic mite that burrows into the skin to lay eggs. This action sets up an intense and itchy inflammation in the skin. This condition is commonly known as scabies. Scabies is highly contagious and can spread through close physical contact with an infected person. The intense itching and inflammation are caused by the body's immune response to the mites and their eggs.

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105. Body louse

Explanation

The correct answer is "sarcoptes scabiei". Sarcoptes scabiei refers to the mite that causes scabies, a contagious skin condition characterized by intense itching and a rash. The other terms mentioned in the question, such as body louse, mycosis, herpes viruses, and pediculus, are not directly related to sarcoptes scabiei or scabies. Hyperbaric, on the other hand, refers to a type of medical treatment involving increased atmospheric pressure, which is also unrelated to sarcoptes scabiei.

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106. This species of mycobacterium infects people with late stage HIV infections

Explanation

Mycobacterium avium is a species of mycobacterium that commonly infects people with late-stage HIV infections. This bacterium is known to cause a type of infection called Mycobacterium avium complex (MAC), which primarily affects individuals with compromised immune systems, such as those with advanced HIV/AIDS. MAC infections can manifest as disseminated infections, affecting multiple organs in the body, including the lungs, lymph nodes, and intestines. Therefore, mycobacterium avium is the correct answer for this question.

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107. Ringworm of the hand

Explanation

Tinea manuum refers to a fungal infection that affects the hands. It is commonly known as ringworm of the hand. This infection is caused by dermatophytes, which are a type of fungus. Tinea manuum typically presents with red, scaly patches on the palms, fingers, and between the fingers. It can cause itching, burning, and discomfort. Treatment usually involves antifungal creams or oral medications.

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108. Fish tapeworm

Explanation

Diphyllobothrium latum is a type of fish tapeworm that infects humans. It is the largest tapeworm that can infect humans and is commonly found in freshwater fish. The infection occurs when humans consume raw or undercooked fish containing the larvae of the tapeworm. Once ingested, the larvae develop into adult worms in the intestines and can cause symptoms such as abdominal pain, diarrhea, and vitamin B12 deficiency. Treatment typically involves medication to kill the tapeworm and its larvae.

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109. Neonatal meningitis is most commonly transmitted by

Explanation

Neonatal meningitis is most commonly transmitted through exposure in the birth canal. During childbirth, the baby can come into contact with bacteria or viruses present in the mother's birth canal, leading to an infection in the baby's central nervous system. This mode of transmission is one of the primary ways in which neonatal meningitis occurs.

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110. Which is not correct about Mycobacterium species?

Explanation

The statement "All species are human pathogens" is not correct about Mycobacterium species. While some species of Mycobacterium can cause diseases in humans, not all species are human pathogens. Some species are harmless and can be found in the environment. Therefore, it is incorrect to say that all species of Mycobacterium are human pathogens.

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111. Lyme Disease

Explanation

Borrelia burgdorferi is the correct answer because it is the bacteria that causes Lyme disease. Lyme disease is a tick-borne illness that can cause a variety of symptoms, including skin manifestations such as macules. Tinea refers to a fungal infection, Rickettsia rickettsii is the bacteria that causes Rocky Mountain spotted fever, and pericarditis is inflammation of the lining around the heart.

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112. This type of anthrax is nearly 100% in its mortality rate

Explanation

Inhalational anthrax is the correct answer because it is known to have a nearly 100% mortality rate. Inhalational anthrax occurs when spores of the bacterium Bacillus anthracis are inhaled into the lungs. These spores can cause severe respiratory distress and can be fatal if not treated promptly. Cutaneous anthrax, subcutaneous anthrax, and gastrointestinal anthrax can also be serious, but they do not have the same high mortality rate as inhalational anthrax. Therefore, none of the other options are correct.

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113. Chinese liver fluke

Explanation

Clonorchis sinensis is the correct answer because it is a type of liver fluke that infects humans. It is commonly found in East Asia, particularly in China, Korea, and Vietnam. This parasite is acquired by consuming raw or undercooked freshwater fish that contain the infective larvae. Clonorchis sinensis can cause a condition called clonorchiasis, which can lead to liver damage, bile duct obstruction, and even liver cancer if left untreated. The other options listed are also types of liver flukes, but they do not specifically refer to Clonorchis sinensis.

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114. Which chemical, produced by S. aureus is also known as "spreading factor"?

Explanation

Hyaluronidase is a chemical produced by S. aureus that is also known as the "spreading factor". This enzyme helps the bacteria to spread and invade tissues by breaking down hyaluronic acid, a component of connective tissue. This allows the bacteria to move through the tissues and cause infection.

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115. Which of the following is not true of meningoencephalitis?

Explanation

Meningoencephalitis is an infection that affects both the brain and the meninges. The causative organisms for meningoencephalitis are typically Naegleria fowleri and Acanthamoeba, which are amoebas, rather than viruses. Therefore, the statement that causative organisms are viruses is not true for meningoencephalitis.

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116. Pork tapeworm

Explanation

Taenia solium is a type of tapeworm that infects humans through the consumption of undercooked pork. It is commonly known as the pork tapeworm. Once ingested, the tapeworm can attach itself to the intestinal wall and grow, causing symptoms such as abdominal pain, nausea, and weight loss. In severe cases, the larvae of T. solium can migrate to other parts of the body and cause serious health complications. Proper cooking of pork and good hygiene practices can help prevent the transmission of T. solium.

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117. Ringworm of the nail

Explanation

Tinea unguium is the correct answer because it refers to a fungal infection of the nails, commonly known as ringworm of the nail. This condition can cause the nails to become discolored, thickened, and brittle. It is usually caused by dermatophyte fungi and can be difficult to treat. Tinea cruris refers to a fungal infection of the groin area, tinea pedis is a fungal infection of the feet, tinea barbae is a fungal infection of the beard area, and tinea manuum refers to a fungal infection of the hands.

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118. The primary viral cause of chronic diarrhea, globally, is

Explanation

Rotavirus is the correct answer because it is a primary viral cause of chronic diarrhea worldwide. Rotavirus is highly contagious and commonly affects infants and young children. It is transmitted through the fecal-oral route and can cause severe diarrhea, vomiting, and dehydration. Rotavirus infections are responsible for a significant number of hospitalizations and deaths in children under the age of five, particularly in developing countries with limited access to clean water and sanitation facilities. Vaccination against rotavirus has been successful in reducing the burden of rotavirus-related diarrhea globally.

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119. The most common cause of liver cancer in the US is

Explanation

HCV, or Hepatitis C virus, is the most common cause of liver cancer in the US. Hepatitis C is a viral infection that primarily affects the liver and can lead to chronic liver disease, cirrhosis, and eventually liver cancer. It is transmitted through contact with infected blood, such as through sharing needles or unsafe medical procedures. HCV infection often goes undiagnosed for many years, leading to the development of liver cancer in some cases. Effective treatments for Hepatitis C are available, but early detection and prevention are crucial in reducing the risk of liver cancer.

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120. The main antiprotozoan drug that is used to treat a variety of protozoan diseases is

Explanation

Metronidazole is the correct answer because it is a widely used antiprotozoal drug that is effective against a variety of protozoan diseases. It works by disrupting the DNA of the protozoa, leading to their death. Praziquantel is mainly used to treat parasitic worm infections, not protozoan diseases. Ketoconazole and Imidazole are antifungal drugs, not antiprotozoal drugs. Amphotericin B is an antifungal drug that can also be used to treat some protozoan infections, but it is not the main drug of choice.

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121. Opisthotonos

Explanation

Tetanus is a bacterial infection caused by the bacterium Clostridium tetani. It is characterized by muscle stiffness and spasms, including a condition known as opisthotonos, where the back muscles contract causing the body to arch backwards. This condition is commonly associated with tetanus and is one of the key symptoms used to diagnose the disease. The other options listed, Trypanosoma brucei gambiense, Naegleria fowleri, Candidiasis, and Meningococcal, do not typically cause opisthotonos and are not directly related to this symptom.

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122. Hardened tubercules

Explanation

Ghon complexes are a characteristic pathological feature of tuberculosis infection. They are formed when the immune response to Mycobacterium tuberculosis leads to the formation of granulomas in the lung tissue. These granulomas consist of a central area of infected macrophages surrounded by lymphocytes and fibrous tissue. Ghon complexes are a sign of active tuberculosis infection and can be seen on chest X-rays. They are named after Anton Ghon, an Austrian pathologist who first described them in 1912.

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123. Protozoan that feeds on RBCs and GI tract tissues

Explanation

Entamoeba histolytica is a protozoan that feeds on red blood cells (RBCs) and gastrointestinal (GI) tract tissues. It is known for causing amoebic dysentery, an infection that leads to severe diarrhea and abdominal pain. This parasite invades the intestinal lining, causing inflammation and destruction of tissues. It can also spread to other organs, such as the liver, causing abscesses. The feeding behavior of Entamoeba histolytica on RBCs and GI tract tissues is what distinguishes it from the other options listed, making it the correct answer.

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124. Larvae encyst in muscles of humans and mammals

Explanation

Trichenella spiralis is a parasitic worm that infects humans and mammals. After ingestion, the larvae of Trichenella spiralis migrate to the muscles, where they encyst. This can lead to a condition called trichinellosis, which is characterized by muscle pain, fever, and gastrointestinal symptoms. Therefore, the given statement "larvae encyst in muscles of humans and mammals" accurately describes the life cycle of Trichenella spiralis.

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125. What type of vaccine is the influenza vaccine?

Explanation

The influenza vaccine is a subunit vaccine. This type of vaccine contains only specific parts or components of the influenza virus, such as proteins or antigens, rather than the whole virus. By focusing on these specific components, the subunit vaccine can stimulate an immune response without causing the actual illness. This makes it a safe and effective option for preventing influenza infections.

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126. What do invasive Group A streptococcus utilize to further spread their infection?

Explanation

Invasive Group A streptococcus utilize streptokinases and hyaluronidases to further spread their infection. Streptokinases are enzymes that dissolve blood clots, allowing the bacteria to move more easily through the bloodstream and invade different tissues. Hyaluronidases, on the other hand, break down the connective tissue in the body, facilitating the bacteria's spread and invasion into surrounding tissues. By utilizing both streptokinases and hyaluronidases, the bacteria are able to effectively spread their infection and cause damage to various parts of the body.

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127. Contributes to the blue-green pus in a pseudomonas infection

Explanation

Pyocyanin is a blue-green pigment produced by the bacteria Pseudomonas aeruginosa, which is known to cause pseudomonas infections. This pigment contributes to the characteristic blue-green color of the pus in these infections. Therefore, pyocyanin is the correct answer as it directly relates to the blue-green pus seen in pseudomonas infections.

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128. Formation of a pseudomembrane in the back of the throat is seen in

Explanation

The formation of a pseudomembrane in the back of the throat is a characteristic feature of diphtheria. Diphtheria is a highly contagious bacterial infection caused by Corynebacterium diphtheriae. The bacteria release toxins that cause the formation of a grayish-white pseudomembrane in the throat, which can obstruct the airway and lead to severe respiratory distress. This pseudomembrane is a result of the body's immune response to the infection and is composed of dead tissue, bacteria, and immune cells. Prompt diagnosis and treatment with antibiotics and antitoxin are essential to prevent complications and spread of the infection.

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129. Which of the following layers is not part of the meninges?

Explanation

The subarachnoid mater is not part of the meninges. The meninges are the three protective layers that surround the brain and spinal cord: the dura mater, arachnoid mater, and pia mater. The subarachnoid mater is a space filled with cerebrospinal fluid that is located between the arachnoid mater and pia mater, but it is not considered a layer of the meninges.

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130. The preferred treatment for suspected lyme disease is

Explanation

Doxycycline is the preferred treatment for suspected Lyme disease because it is effective against the bacteria that causes the disease, Borrelia burgdorferi. It is a broad-spectrum antibiotic that can penetrate tissues well, including the central nervous system where the bacteria may reside. Doxycycline is also well-tolerated and has a good safety profile. It is usually prescribed for a duration of 14 to 21 days, depending on the severity of the infection. Other antibiotics like penicillin, ciprofloxacin, quinine, and chloroquine are not typically used as first-line treatments for Lyme disease.

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131. Amoebic protozoan found in ponds and streams that causes a lethal brain infection

Explanation

Naegleria fowleri is a correct answer because it is an amoebic protozoan that is commonly found in warm freshwater environments such as ponds and streams. It is known to cause a rare but lethal brain infection called primary amebic meningoencephalitis (PAM). PAM is usually acquired when contaminated water enters the body through the nose, allowing the amoeba to travel to the brain. This infection is often fatal, with a high mortality rate. Therefore, Naegleria fowleri is the correct answer as it matches the description given in the question.

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132. A disease where the agent is able to evade the host's antibodies through antigenic variation is

Explanation

African trypanosomiasis, also known as sleeping sickness, is caused by the parasite Trypanosoma brucei. This disease is able to evade the host's antibodies through antigenic variation. The parasite constantly changes its surface antigens, making it difficult for the host's immune system to recognize and eliminate it. This allows the parasite to persist in the host and cause chronic infection.

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133. Mycobacterium leprae

Explanation

The correct answer is A and C. Mycobacterium leprae is the causative agent of leprosy and is an acid-fast rod that grows best at 37°C. This bacterium primarily infects peripheral nerve and skin cells, leading to the development of leprosy.

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134. Fish tapeworm

Explanation

Diphyllobothrium latum is a type of fish tapeworm that infects humans. It is the largest tapeworm that can infect humans and is commonly found in freshwater fish. The infection occurs when a person consumes raw or undercooked fish that is contaminated with the tapeworm larvae. Once ingested, the tapeworm grows and attaches itself to the intestines, causing symptoms such as abdominal pain, diarrhea, and weight loss. Treatment involves medication to kill the tapeworm and its larvae.

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135. All of the following are inhibitors of protein synthesis except

Explanation

Sulfonamides are not inhibitors of protein synthesis. Tetracyclines, chloramphenicol, macrolides, and aminoglycosides are all known to inhibit protein synthesis in different ways. Sulfonamides, on the other hand, work by inhibiting the synthesis of folic acid, which is an essential component for bacterial growth. Therefore, sulfonamides are not considered inhibitors of protein synthesis.

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136. Which of the following statements is NOT true about Clostridium tetani?

Explanation

The given correct answer is "none of the above." This means that all of the statements provided about Clostridium tetani are true. Clostridium tetani is indeed the causative agent of tetanus. It produces tetanospasmin, a neurotoxin that blocks the relaxation pathway in muscles. It is a gram-positive bacterium that forms endospores and is an obligate anaerobe. Additionally, it may cause opisthotonos, a condition characterized by severe muscle spasms and arching of the back.

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137. A nosocomial infection caused by streptococcus pyogenes Group A made uncommon by antibiotics and modern hygienic practices

Explanation

Puerperal sepsis is a type of infection that occurs in women after childbirth, typically caused by bacteria entering the reproductive tract during delivery. In the past, before the advent of antibiotics and modern hygienic practices, puerperal sepsis was more common. However, with the use of antibiotics and improved hygiene in healthcare settings, the incidence of puerperal sepsis has decreased significantly. This explanation aligns with the given statement that puerperal sepsis is made uncommon by antibiotics and modern hygienic practices.

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138. This new class of drugs will interfere with the virus inserting itself into host DNA:

Explanation

Fusion inhibitors are a new class of drugs that work by preventing the virus from fusing with the host cell membrane, thus blocking the entry of the virus into the host cell. By inhibiting this fusion process, the virus is unable to insert itself into the host DNA and replicate. This mechanism of action makes fusion inhibitors an effective treatment option for viral infections by interfering with the initial stages of the viral life cycle. Therefore, it is correct to say that fusion inhibitors will interfere with the virus inserting itself into host DNA.

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139. All of the following microorganisms contribute to digestive system diseases except

Explanation

Mycobacterium is the correct answer because it is not typically associated with causing digestive system diseases. Cryptosporidium, Girardia, and Vibrio are all known to cause various digestive system diseases such as diarrhea, abdominal pain, and gastrointestinal infections. Therefore, mycobacterium is the exception in this list.

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140. The vector of the bubonic plague is

Explanation

Xenopsylla is the correct answer because it is the vector responsible for transmitting the bubonic plague. Xenopsylla cheopis, also known as the oriental rat flea, is the primary vector for the bacterium Yersinia pestis, which causes the bubonic plague. This flea feeds on the blood of rodents infected with the bacterium and can transmit it to humans through its bite. Therefore, xenopsylla is the vector that plays a crucial role in the transmission of the bubonic plague.

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141. Production of a neurotoxin that prevents acetylcholine release from motor neurons at neuromuscular junctions is a characteristic of

Explanation

Clostridium botulinum produces a neurotoxin that inhibits the release of acetylcholine from motor neurons at neuromuscular junctions. This neurotoxin is responsible for causing botulism, a serious illness characterized by muscle weakness and paralysis. Clostridium perfringens, Clostridium difficile, and Clostridium tetani are also pathogenic bacteria, but they do not produce the specific neurotoxin that prevents acetylcholine release. Therefore, the correct answer is Clostridium botulinum.

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142. Pinworm

Explanation

Enterobius vermicularis is the correct answer because it is commonly known as pinworm. Pinworm is a parasitic worm that infects the intestines of humans and causes symptoms such as itching around the anus, especially at night. It is a common infection, particularly in children, and is transmitted through the ingestion of pinworm eggs. Treatment usually involves medication to kill the worms and prevent re-infection.

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143. Protozoan parasite diagnosed by acid-fast staining of stool or ELISA

Explanation

Cryptosporidium parvum is a protozoan parasite that can be diagnosed by acid-fast staining of stool or ELISA. Acid-fast staining is a technique used to identify organisms that have a waxy cell wall, such as certain bacteria and parasites. ELISA (enzyme-linked immunosorbent assay) is a diagnostic test that detects specific antibodies or antigens in a sample. Therefore, the correct answer, Cryptosporidium parvum, is the only option that fits the given diagnostic methods.

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144. Mucous membrane rash arising from another focus of infection

Explanation

Enanthem refers to a rash that appears on the mucous membranes, such as the inside of the mouth or throat. It can occur as a result of an infection in another part of the body, which then spreads to the mucous membranes. This can happen with various types of infections, including viral infections like papillomaviruses. Therefore, enanthem is a plausible explanation for a mucous membrane rash arising from another focus of infection.

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145. Hutchinson's teeth are

Explanation

Hutchinson's teeth are a symptom of congenital syphilis. Syphilis is a sexually transmitted infection that can be passed from mother to baby during pregnancy. Hutchinson's teeth are a specific dental abnormality that occurs in children with congenital syphilis. These teeth are smaller and more widely spaced than normal, with notched incisors and a characteristic screwdriver-shaped appearance. Therefore, the correct answer is that Hutchinson's teeth are a symptom of congenital syphilis.

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146. Normal microbiota of the skin include all of the following except

Explanation

The normal microbiota of the skin consists of various bacteria that naturally reside on the skin surface. Micrococcus, Staphylococcus, Corynebacterium, and Propionibacterium are all examples of bacteria that are part of the normal skin microbiota. However, Bacillus is not typically found as a part of the normal skin microbiota.

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147. Hookworm

Explanation

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148. Intestinal roundworm

Explanation

Ascaris lumbricoides is the correct answer because it is a type of intestinal roundworm that commonly infects humans. It is one of the most common parasitic worms found in the intestines and can cause a condition called ascariasis. The adult worms can grow up to 35 cm long and lay thousands of eggs, which are then passed in the feces of infected individuals. Ingesting food or water contaminated with these eggs can lead to infection. Symptoms of ascariasis may include abdominal pain, diarrhea, and malnutrition. Treatment typically involves medication to kill the worms and relieve symptoms.

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149. Which of the following organisms causes urinary tract infections?

Explanation

Proteus mirabilis is a bacterium that is known to cause urinary tract infections (UTIs). It is a common cause of UTIs, particularly in individuals with underlying urinary tract abnormalities or catheterization. Proteus mirabilis is a gram-negative bacterium that can colonize and infect the urethra, bladder, and kidneys, leading to symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain. It is important to identify and treat infections caused by Proteus mirabilis promptly to prevent complications and recurrence.

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150. Threadworm

Explanation

Strongyloides stercoralis is the correct answer because it is a parasitic threadworm that infects humans. It is commonly found in tropical and subtropical regions and can cause a condition called strongyloidiasis. The infection occurs when the larvae of the worm penetrate the skin or are ingested through contaminated food or water. Once inside the body, the larvae migrate to the lungs and then the intestines, where they mature into adult worms. Symptoms of strongyloidiasis can vary but may include abdominal pain, diarrhea, and skin rashes. Treatment usually involves antiparasitic medications.

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151. The assay to detect the presence of antibodies against the HIV virus is a(n)

Explanation

The correct answer is Indirect ELISA. In an indirect ELISA, the HIV antigen is immobilized on a solid surface and patient's serum is added. If antibodies against HIV are present in the serum, they will bind to the antigen. Then, a secondary antibody that is specific to human antibodies is added, which binds to the HIV antibodies. This secondary antibody is usually labeled with an enzyme that produces a color change when a substrate is added. The color change indicates the presence of HIV antibodies in the patient's serum.

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152. Necrotizing fasciitis is

Explanation

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153. Which drugs interfere with the action of an HIV enzyme needed for final assembly and maturation of the virus?

Explanation

Protease inhibitors interfere with the action of an HIV enzyme needed for the final assembly and maturation of the virus. These drugs inhibit the activity of the protease enzyme, which is responsible for cutting the long HIV protein chains into smaller, functional proteins. By inhibiting this enzyme, protease inhibitors prevent the virus from assembling and maturing into an infectious form. Therefore, protease inhibitors are effective in reducing the replication and spread of HIV in the body.

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Inflammation of the sac around the heart
Small fluid-filled lesions on the skin
Ringworm of the feet
The most common cause of vaginitis is
Protozoan disease that causes irritation and profuse discharge in...
African sleeping sickness
Lyme disease is transmitted by
Oral lesions called Koplik's spots are seen in patients with
Thrush
What is the bacterium responsible for inflammatory acne?
Genital warts
Which organism is a common cause of meningitis in AIDS patients and...
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever
Meningitis is caused by the bacterium Neisseria meningitidis
Blood is a mixture of all of the following
Neurotoxin that blocks the nerve pathway that signals muscle...
A diagnosis of tuberculosis involves
One virulence factor of Mycobacterium leprae is the ability to live...
Growth of bacteria in the blood
Grave's disease is an immune reaction against the thyroid gland...
The causative agent of the bubonic plague is
A fungal infection of the body
Disease caused by the bite of the anopheles mosquito
Cells that may ingest tuberculosis bacilli
The oily secretion that lubricates the hair follicles of the skin is
Pathogen grows at refrigerator temperatures
Which of the following provides the eye with its best defense against...
Whooping cough
Which of the following methods can be used as a diagnosis of syphilis?
Trypanosoma cruzi is the causative agent of
Ringworm of the beard
The most immediate and important treatment needed to prevent death in...
T cells attack the myelin sheath of the nervous system
German measles is caused by
Sheep liver fluke
Gp120 binds to
The normal biota of the CNS consists of
__________ occurs when bacteria flourish and grow in the blood stream.
All of the following pertain to patients with AIDS except
Infection of the dermal layer of the skin by streptococcus pyogenes
Shingles
Ringworm
"Rice water stools" are associated with disease caused by...
Impetigo is caused by
Which of the following is a sexually transmitted disease?
The fibrous sac that encloses the heart is the
Ringworm
The main causative agent of gas gangrene is
Shiga toxin
Helicobacter pylori appears to have some connection with
Carries Malaria
Infections caused by obligate anaerobes such as clostridium...
Neurotoxin produced by dinoflagellates
Blood flukes
Syphilis
Diphtheria
The toxin of Staphylococcus aureus strains that causes blisters and...
Candida albicans is a
The loss of blood supply to tissue is referred to as
Cause of many dental caries
This freshwater amoeba used to be associated with unsanitary contact...
This disease is a result of an autoimmune complication of repeat...
This protozoan parasite is found in healthy human lungs, waiting for a...
Which of the following is not true of bacterial conjunctivitis?
Flat reddened lesions
Bacterial meningitis is caused by all of the following except
This soil fungus, associated with pigeon and chicken droppings, can...
Ringworm of the groin
What material in skin cells provides protection from abrasions, water...
Which is incorrect about warts?
Blood fluke
Valuable source of many commercial antibiotics
This virus, transmitted by an animal bite, multiplies in skeletal...
This arthropod vector is responsible for carrying the causative agent...
Reactivation of chickenpox is called
Symptoms of cryptosporidiosis include
American dog tick
The serotype of influenza that causes most epidemics is serotype
Which of the following genera is responsible for causing gonorrhea?
All of the following are pre-disposing factors that contribute to...
Necator and ancylostoma are both human
MRSAs are S. aureus strains that are
Permanent cardiovascular and neurological damage is seen in which...
About 60% of the bacterial pneumonias that require hospitalization of...
What brain defense restricts substances from entering the brain by the...
The major agents responsible for the common cold are
Koplick's spots on the oral mucosa are a useful diagnosis for the
Blood fluke
Which of the following is not true of Ebola and Marburg?
Primary atypical walking pneumonia is caused by
Gram-positive sepsis is caused by all of the following except
The fecal-oral cycle can be broken by all of the following methods...
Production of enterotoxin is a characteristic of
Which of the following diseases is NOT a staphylococcal skin...
All of the following microorganisms exist in large numbers in the...
Anthrax is
Pork tapeworm
Production of a neurotoxin that binds to target sites on spinal cord...
Retroviruses have the following characteristics except
A frequent cancer that is seen in AIDS patients is
Type of spike used by influenza virus to release virus from cells
Human roundworm
Burrows in the skin to lay eggs that sets up intense, itchy...
Body louse
This species of mycobacterium infects people with late stage HIV...
Ringworm of the hand
Fish tapeworm
Neonatal meningitis is most commonly transmitted by
Which is not correct about Mycobacterium species?
Lyme Disease
This type of anthrax is nearly 100% in its mortality rate
Chinese liver fluke
Which chemical, produced by S. aureus is also known as "spreading...
Which of the following is not true of meningoencephalitis?
Pork tapeworm
Ringworm of the nail
The primary viral cause of chronic diarrhea, globally, is
The most common cause of liver cancer in the US is
The main antiprotozoan drug that is used to treat a variety of...
Opisthotonos
Hardened tubercules
Protozoan that feeds on RBCs and GI tract tissues
Larvae encyst in muscles of humans and mammals
What type of vaccine is the influenza vaccine?
What do invasive Group A streptococcus utilize to further spread their...
Contributes to the blue-green pus in a pseudomonas infection
Formation of a pseudomembrane in the back of the throat is seen in
Which of the following layers is not part of the meninges?
The preferred treatment for suspected lyme disease is
Amoebic protozoan found in ponds and streams that causes a lethal...
A disease where the agent is able to evade the host's antibodies...
Mycobacterium leprae
Fish tapeworm
All of the following are inhibitors of protein synthesis except
Which of the following statements is NOT true about Clostridium...
A nosocomial infection caused by streptococcus pyogenes Group A made...
This new class of drugs will interfere with the virus inserting itself...
All of the following microorganisms contribute to digestive system...
The vector of the bubonic plague is
Production of a neurotoxin that prevents acetylcholine release from...
Pinworm
Protozoan parasite diagnosed by acid-fast staining of stool or ELISA
Mucous membrane rash arising from another focus of infection
Hutchinson's teeth are
Normal microbiota of the skin include all of the following except
Hookworm
Intestinal roundworm
Which of the following organisms causes urinary tract infections?
Threadworm
The assay to detect the presence of antibodies against the HIV virus...
Necrotizing fasciitis is
Which drugs interfere with the action of an HIV enzyme needed for...
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