Mic 541 Exam 4 - Mycology I And II

45 Questions | Total Attempts: 5511

SettingsSettingsSettings
Please wait...
Mycology Quizzes & Trivia

MIC 541 Exam 4 - Mycology I and II


Questions and Answers
  • 1. 
    Fungi are a main cause of human infection.
    • A. 

      True

    • B. 

      False

  • 2. 
    Infections from fungi occur mostly due to:
    • A. 

      Disruption of natural barriers

    • B. 

      Immunosuppression

    • C. 

      Occupational contact

    • D. 

      All of the above

  • 3. 
    Fungi reproduce by which fo the following?
    • A. 

      Fission, as in bacteria

    • B. 

      Budding – mostly in yeasts

    • C. 

      Fragmentation of hyphae

    • D. 

      Spore formation by mold forms

  • 4. 
    Fungi that infect outside layers of skin or hair only are classified as?
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 5. 
    Fungi that invade skin, hair, nails are classified as?
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 6. 
    Fungi that are localized and enter by trauma are classified as?
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 7. 
    Fungi that are more virulent and cause disease in healthy hosts are classified as?
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 8. 
    Fungi that infect only infect compromised hosts are clasified as?
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 9. 
    Which part of the fungal cell should a drug target so as to cause the least amount of damage to the human host?
    • A. 

      Cholesterol in cell membrane

    • B. 

      Ergosterol in cell membrane

    • C. 

      Nucleus

  • 10. 
    Which antifungal drug binds to ergosterol in the fungal membrane and forms pores in the membrane?
    • A. 

      Amphotericin

    • B. 

      5-fluorocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Caspofungin

  • 11. 
    Amphotericin causes the cell to be leaky, which alters its permeability to which of the following?
    • A. 

      Mg

    • B. 

      Na

    • C. 

      Cl

    • D. 

      K

  • 12. 
    A person can only get a certain amount of Amphotercin in his/her lifetime.
    • A. 

      True

    • B. 

      False

  • 13. 
    Which drug do fungi take it up using a permease that our cells do not make.  It gets incorporated into the fungal RNA in place of uracil. 
    • A. 

      Amphotericin

    • B. 

      5-fluorocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Caspofungin

  • 14. 
    The fungal cells can develop a resistance to *this drug* if given by itself, so it is usually given in combination with Amphotericin B
    • A. 

      5-fluorocytosine

    • B. 

      Terbinafine

    • C. 

      The azoles

    • D. 

      Capsofungin

  • 15. 
    This drug is good for fungal meningitis since it can enter the CNS.
    • A. 

      Amphotericin

    • B. 

      5-fluorocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Capsofungin

  • 16. 
    Which antifungal drug Blocks squalene epoxidase enzyme to prevent squalene conversion to ergosterol. 
    • A. 

      Amphotericin

    • B. 

      5-flurocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Capsofungin

  • 17. 
    Which of the following are characteristic of terbinafine?
    • A. 

      Given orally

    • B. 

      Given topically

    • C. 

      Used to treat dermatophytes

    • D. 

      Used to treat nail infections

  • 18. 
    Which antifungal drug inhibits cytochromes (cytochrome P450)?  This prevents ergosterol formation, which disrupts membrane function and growth
    • A. 

      Amphotericin

    • B. 

      5-flurocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Capsofungin

  • 19. 
    Which antifungal drug can have the following side effects?males – may develop breastsfemales – irregular menstrual cyclesliver toxicity
    • A. 

      Amphotericin

    • B. 

      5-flurocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Capsofungin

  • 20. 
    Thiazoles have the same SE but are less toxic than imidazoles
    • A. 

      True

    • B. 

      False

  • 21. 
    Which antifungal drug Inhibits β-(1,3)-D-glucan synthesis, which usually makes the cross-bridges in the fungal cell wall.  Therefore cell wall formation is inhibited
    • A. 

      Amphotericin

    • B. 

      5-flurocytosine

    • C. 

      The azoles

    • D. 

      Terbinafine

    • E. 

      Capsofungin

  • 22. 
    Which of the following are Imidazoles that  are used as–topical replacements for nystatin 
    • A. 

      Ketoconazole

    • B. 

      Clotrimazole

    • C. 

      Miconazole

    • D. 

      Voriconazole

  • 23. 
    Fluconazole is used to treat meningitis, because it can attain good CNS levels
    • A. 

      True

    • B. 

      False

  • 24. 
    Echinocandins is a class of antifungals that act as a fungicidal for Candida and also work against Aspergillus
    • A. 

      True

    • B. 

      False

  • 25. 
    Nystatin is a polyene similar to Amphotericin B.
    • A. 

      True

    • B. 

      False

Back to Top Back to top