Mic 541 Exam 4 - Mycology I And II

45 Questions | By Cdtiller | Updated: Dec 2, 2022 | Attempts: 7633

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MIC 541 Exam 4 - Mycology I and II

Questions and Answers

1.

Fungi are a main cause of human infection.
- A.
  
  True
- B.
  
  False
2.

Infections from fungi occur mostly due to:
- A.
  
  Disruption of natural barriers
- B.
  
  Immunosuppression
- C.
  
  Occupational contact
- D.
  
  All of the above
3.

Fungi reproduce by which fo the following?
- A.
  
  Fission, as in bacteria
- B.
  
  Budding – mostly in yeasts
- C.
  
  Fragmentation of hyphae
- D.
  
  Spore formation by mold forms
4.

Fungi that infect outside layers of skin or hair only are classified as?
- A.
  
  Superficial
- B.
  
  Cutaneous
- C.
  
  Subcutaneous
- D.
  
  Systemic
- E.
  
  Opportunistic
5.

Fungi that invade skin, hair, nails are classified as?
- A.
  
  Superficial
- B.
  
  Cutaneous
- C.
  
  Subcutaneous
- D.
  
  Systemic
- E.
  
  Opportunistic
6.

Fungi that are localized and enter by trauma are classified as?
- A.
  
  Superficial
- B.
  
  Cutaneous
- C.
  
  Subcutaneous
- D.
  
  Systemic
- E.
  
  Opportunistic
7.

Fungi that are more virulent and cause disease in healthy hosts are classified as?
- A.
  
  Superficial
- B.
  
  Cutaneous
- C.
  
  Subcutaneous
- D.
  
  Systemic
- E.
  
  Opportunistic
8.

Fungi that infect only infect compromised hosts are clasified as?
- A.
  
  Superficial
- B.
  
  Cutaneous
- C.
  
  Subcutaneous
- D.
  
  Systemic
- E.
  
  Opportunistic
9.

Which part of the fungal cell should a drug target so as to cause the least amount of damage to the human host?
- A.
  
  Cholesterol in cell membrane
- B.
  
  Ergosterol in cell membrane
- C.
  
  Nucleus
10.

Which antifungal drug binds to ergosterol in the fungal membrane and forms pores in the membrane?
- A.
  
  Amphotericin
- B.
  
  5-fluorocytosine
- C.
  
  Terbinafine
- D.
  
  The azoles
- E.
  
  Caspofungin
11.

Amphotericin causes the cell to be leaky, which alters its permeability to which of the following?
- A.
  
  Mg
- B.
  
  Na
- C.
  
  Cl
- D.
  
  K
12.

A person can only get a certain amount of Amphotercin in his/her lifetime.
- A.
  
  True
- B.
  
  False
13.

Which drug do fungi take it up using a permease that our cells do not make. It gets incorporated into the fungal RNA in place of uracil.
- A.
  
  Amphotericin
- B.
  
  5-fluorocytosine
- C.
  
  Terbinafine
- D.
  
  The azoles
- E.
  
  Caspofungin
14.

The fungal cells can develop a resistance to *this drug* if given by itself, so it is usually given in combination with Amphotericin B
- A.
  
  5-fluorocytosine
- B.
  
  Terbinafine
- C.
  
  The azoles
- D.
  
  Capsofungin
15.

This drug is good for fungal meningitis since it can enter the CNS.
- A.
  
  Amphotericin
- B.
  
  5-fluorocytosine
- C.
  
  Terbinafine
- D.
  
  The azoles
- E.
  
  Capsofungin
16.

Which antifungal drug Blocks squalene epoxidase enzyme to prevent squalene conversion to ergosterol.
- A.
  
  Amphotericin
- B.
  
  5-flurocytosine
- C.
  
  Terbinafine
- D.
  
  The azoles
- E.
  
  Capsofungin
17.

Which of the following are characteristic of terbinafine?
- A.
  
  Given orally
- B.
  
  Given topically
- C.
  
  Used to treat dermatophytes
- D.
  
  Used to treat nail infections
18.

Which antifungal drug inhibits cytochromes (cytochrome P450)? This prevents ergosterol formation, which disrupts membrane function and growth
- A.
  
  Amphotericin
- B.
  
  5-flurocytosine
- C.
  
  Terbinafine
- D.
  
  The azoles
- E.
  
  Capsofungin
19.

Which antifungal drug can have the following side effects?males – may develop breastsfemales – irregular menstrual cyclesliver toxicity
- A.
  
  Amphotericin
- B.
  
  5-flurocytosine
- C.
  
  Terbinafine
- D.
  
  The azoles
- E.
  
  Capsofungin
20.

Thiazoles have the same SE but are less toxic than imidazoles
- A.
  
  True
- B.
  
  False
21.

Which antifungal drug Inhibits β-(1,3)-D-glucan synthesis, which usually makes the cross-bridges in the fungal cell wall. Therefore cell wall formation is inhibited
- A.
  
  Amphotericin
- B.
  
  5-flurocytosine
- C.
  
  The azoles
- D.
  
  Terbinafine
- E.
  
  Capsofungin
22.

Which of the following are Imidazoles that are used as–topical replacements for nystatin
- A.
  
  Ketoconazole
- B.
  
  Clotrimazole
- C.
  
  Miconazole
- D.
  
  Voriconazole
23.

Fluconazole is used to treat meningitis, because it can attain good CNS levels
- A.
  
  True
- B.
  
  False
24.

Echinocandins is a class of antifungals that act as a fungicidal for Candida and also work against Aspergillus
- A.
  
  True
- B.
  
  False
25.

Nystatin is a polyene similar to Amphotericin B.
- A.
  
  True
- B.
  
  False

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