Lynch Syndrome Risk Models

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| By Michellecmartin
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Michellecmartin
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Quizzes Created: 1 | Total Attempts: 313
| Attempts: 313 | Questions: 7
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1. Which model requires that the proband be affected with colorectal cancer?

Explanation

MMRPredict is the model that requires the proband to be affected with colorectal cancer. This means that in order to use the MMRPredict model, the individual being tested must have a history of colorectal cancer. The other models listed, PREMM1,2,6 and MMRpro, do not have this requirement.

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Lynch Syndrome Risk Models - Quiz

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2. Which model provides cancer risk estimates in addition to mutation risks?

Explanation

MMRpro is the model that provides cancer risk estimates in addition to mutation risks. This model is specifically designed to assess the risk of colorectal cancer in individuals with Lynch syndrome. It incorporates various factors such as age, sex, family history, and tumor characteristics to calculate an individual's lifetime risk of developing colorectal cancer. By providing both mutation risks and cancer risk estimates, MMRpro allows healthcare professionals to better understand and communicate the potential risks to their patients.

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3. Which model estimates the risk that a patient will carry a PMS2 mutation?

Explanation

None of the above models estimate the risk that a patient will carry a PMS2 mutation.

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4. What does ROC Curve stand for?

Explanation

The ROC Curve stands for Receiver Operating Characteristic Curve. This curve is a graphical representation of the performance of a binary classifier system as its discrimination threshold is varied. It shows the trade-off between the true positive rate (sensitivity) and the false positive rate (1-specificity). The ROC curve is commonly used in machine learning and diagnostic medicine to evaluate the performance of classification models.

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5. Which model does not account for tumor location or MSI/IHC?

Explanation

PREMM1,2,6 is the model that does not account for tumor location or MSI/IHC. This means that when using this model, the prediction or analysis does not take into consideration the specific location of the tumor or the results of MSI/IHC testing.

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6. Did the webcast improve your knowledge about Lynch syndrome risk models?

Explanation

The webcast improved the knowledge about Lynch syndrome risk models.

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7. Was the information presented useful to you?

Explanation

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  • Mar 20, 2023
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  • Aug 27, 2012
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Which model requires that the proband be affected with colorectal...
Which model provides cancer risk estimates in addition to mutation...
Which model estimates the risk that a patient will carry a PMS2...
What does ROC Curve stand for?
Which model does not account for tumor location or MSI/IHC?
Did the webcast improve your knowledge about Lynch syndrome risk...
Was the information presented useful to you?
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