Let's Test Your Immunology Knowledge

15 Questions | By Shpatel128 | Updated: Mar 20, 2022 | Attempts: 323

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1.

What is the major characteristic of Type IV hypersensitivity?
- A.
  
  Mediated by complement
- B.
  
  Mediated by T cells
- C.
  
  Mediated by B cells
- D.
  
  Mediated by IgG, IgE and IgM
2.

Maryann was gardening in her backyard. She decided to pull some of the plants that were growing into her garden. Two days later, she got a rash on her arms. What is a possible reasoning behind her rash?
- A.
  
  She was exposed to poison ivy for the first time.
- B.
  
  It is a local skin reaction due to complement reaction.
- C.
  
  She was already sensitized from poison ivy once and this is the second time she was exposed to poison ivy.
- D.
  
  Her CD8 cells became CTL and memory T cells.
3.

John was in a car accident. He was rushed into the ER. The doctors did not have his medical history so they had administered a Tetanus shot. If John has recieved the tetanus vaccine before, what would be his symptoms?
- A.
  
  Nothing
- B.
  
  He got a rash, glomerulonephritis, or arthritis because inflammation from complement
- C.
  
  His blood vessels burst.
- D.
  
  Inflammation in the area of the shot because his IgG will bind quickly to the antigen in the vaccine
4.

Which of the following is the correct sequence of events when someone has serum sickness?
- A.
  
  Patient is injected with anti-venome horse antibodies --> Patient makes human anti-horse antibodies --> activation of complement --> 7-10 days layer, will get symptoms
- B.
  
  Patient is injected with anti-venome horse antibodies --> Patient makes human anti-horse antibodies --> activation of complement --> 7-10 days layer, will not get symptoms
- C.
  
  Patient is injected with anti-horse antibodies --> Patient makes human anti-horse antibodies --> activation of complement --> 7-10 days layer, will get symptoms
- D.
  
  Patient is injected with anti-venome horse antibodies --> Patient makes human anti-horse antibodies --> activation of complement --> Will get symptoms right away
5.

Where are the most common areas of the body where there is immune complex deposition or damage?
- A.
  
  Kidneys, blood vessels or joints
- B.
  
  Kidneys, blood vessels or pancreas
- C.
  
  Blood vessels, joints, pancreas
- D.
  
  GI tract, joints, skin
6.

Which of the following reasons defines why a PPD test (type IV) cannot produce an immune response?
- A.
  
  It is given in high dosage
- B.
  
  It is injected into the muscle
- C.
  
  There is components that follow inflammation
- D.
  
  It is a purified protein
7.

Which of the following are correctly matched?
- A.
  
  Type IV- allergy
- B.
  
  Type II- skin graft
- C.
  
  Type III- serum sickness
- D.
  
  Type 1- lupus
8.

There is a patient that needs a skin graft. He is unaware that within several months of him receiving the skin graft, his body is going to reject it. Which of the following processes occur to describe this phenomena?
- A.
  
  The skin graft is phagocytosed by a macrophage and destroyed by respiratory burst
- B.
  
  CD8 T cells are strongly reactive to foreign MHCI because it did not go through negative selection
- C.
  
  There is a low affinity between the TCR and graft MHCI
- D.
  
  His body will attack his own MHCI
9.

In Type III hypersensitivity, IgG binds with a soluble antigen. This later results in inflammation. What the primary reason for inflammation to occur?
- A.
  
  IgG binds with the antigen and causes it to explode
- B.
  
  IgG binding with antigen activates the immune response causing formation of IgE
- C.
  
  IgG binding with antigen activates the complement pathway which forms a lot of C3a and C5a components
- D.
  
  Because of the antigen-antibody complex
10.

A patient comes into your office complaining of continous muscle weakness. You order an MRI which shows MS. From your knowledge of MS, what can you infer is the immunological cause?
- A.
  
  Activation of macrophage from activated Th1 cells which is activated by the macrophage with myelin basic protein
- B.
  
  Activation of macrophage from activated Th1 cells which will activate oligodendrocytes to reverse their role
- C.
  
  Activations of macrophages from activated Th2 cells which will activate macrophages which is cut out patches of myelin
- D.
  
  Activation of macrophages from activated CD8 cells will activate macrophages with myeline basic protein
11.

Which of the following describes a Hepatitis B subunit vaccine?
- A.
  
  Vaccines uses only proteins from other species
- B.
  
  Vaccines uses only a particular component of the virus such as proteins
- C.
  
  Vaccine uses entire component of virus
- D.
  
  It is not a subunit vaccine
12.

What are helper substances that induce inflammation used in conjunction with a vaccine?
- A.
  
  Adjuvants
- B.
  
  Conjugate vaccines
- C.
  
  Purified vaccines
- D.
  
  Subunit vaccines
13.

Which of the following is a characteristic with live-attentuated vaccines?
- A.
  
  The person vaccinated develops active immunity
- B.
  
  They are less effective and short lived
- C.
  
  THey are very effective and long lived
- D.
  
  They need repeated boosters
14.

Many bacterial diseases results from toxic proteins that are released by the bacteria. Which of the following is in vaccines that aids in purifying and inactivating the toxin?
- A.
  
  Toxoid
- B.
  
  Adjuvant
- C.
  
  Pathogen
- D.
  
  Formalin
15.

When a mother is given RhoGam prior to her pregnancy to protect from the formation of IgG anti-Rh antibodies, what type of immunization is that?
- A.
  
  Active
- B.
  
  Passive
- C.
  
  Live
- D.
  
  Innate