Immunology Self Test

1. How is contact sensitivity diagnosed?

Patch testing

A red rash is acute, a scaling rash is chronic

Case history of symptom type and onset

Location

All of the above

2. Which is associated with a butterfly rash on nose and cheeks?

Type I diabetes

Systemic lupus erythematosus

Pernicious anemia

Myasthenia gravis

Guiellain-Barre

3. Which vaccines use microbes that were cultured in a way that made them lose their virulence?

Whole organism vaccines

RDNA technology vaccines

Attenuated vaccines

Trojan horse vaccines

Live vaccines

4. Which of the following is an example of a toxoid vaccine?

Bubonic plague

Dipththeria

Haemophilus influenzae type B

Hepatitis B

MMR

5. Which of the following measures forced expiratory volume in one second?

Handheld peak flow meter

Plethysmograph

Spirometer

Graduated cylinder

6. Which results from underproduction of thyroxine?

Grave's disease

Hashimoto's thyroiditis

Systemic lupus erythematosus

Sjogren's syndrome

Pernicious anemia

7. Which of the following is a capsular vaccine? (two answers)

HPV

Pneumococcus

Polio

Meningococcus

Pertussis

Submit

8. Which is false about type I diabetes?

It affects 1:500 in the United States

It usually shows up in middle age (40-50 years)

Symptoms are ketoacidosis, cardiovascular disease and kidney problems

It involves destruction of the islets of Langerhaans

It is treated with insulin injections

9. Which is not an example of an antihistamine?

Singulair

Claritin

Allegra

Zyrtec

Benadryl

10. Which is false?

Anergy = a lack of reaction by the body's defense mechanisms to foreign substances

People with autoimmune disorders have immune complexes in their serum

Autoimmune diseases are usually reversible

Autoantibodies often found, but are not unique

The second most common autoimmune disorder in the United States is Rheumatoid arthritis.

11. Which cancer is not associated with a oncogenic microbe?

Pancreatic cancer

Liver cancer

Cervical cancer

Stomach cancer

12. Which is false about contact sensitivity?

Nickel is the most frequent contact allergen in females over 8 years old.

Reactions to rubber products are usually caused by chemicals added in the manufacturing process,not to the rubber itself.

Poison ivy reaction is to an oil in the plant called urushiol.

Prolonged use of corticosteroid cream, which is used for allergies, can cause a reaction itself.

13. Increased incidence of stomach cancer is seen in patients with:

Pernicious/megaloblastic anemia

Type I diabetes

Rheumatoid arthritis

Grave's disease

Systemic lupus erythematosus

14. Which is not an effective of histamine?

Bronchoconstriction

Vasodilation

Mucus secretion

Inflammation

15. Which is not an effect of leukotrienes?

Bronchoconstriction

Vasodilation

Mucus secretion

Inflammation

16. Which is false about Type I (allergic) hypersensitivity?

It is believed to be a T cell -mediated disease

It is believed to represent a faulty response to parasites

IgE binds to mast cells and basophils

IgE is made that is specific to an allergen

Mast cells in tissue and basophils in blood stream are thought to be counterparts of each other.

17. Ptosis is a sign of which of the following diseases?

Grave's disease

Hashimoto's thyroiditis

Guellain Barre

Myasthenia gravis

Type I diabetes

18. Which vaccines use fragments or proteins of virulent microbes?

Killed

Attenuated

Toxoid

Subunit

Capsular

19. Autoimmune diseases

Affect females and males equally

Affect mostly children and teenagers

Are lifelong and progressive

Involve humoral and/or cellular immune mechanisms

Are non-progressive

20. Which is an example of an anti-leukotriene?

Advair

Singulair

Flovent

Ventolin

Zyrtec

21. Natural active immunity

Is IgG passed from mother to child

Is efficient at fighting infection on the first exposure

Tricks the body into thinking it is being invaded, so the body generates a memory of the event

Requires about two weeks for the cellular immune response to be activated

Requires large amounts of antigen to be injected into the mucosa

22. Which is not a killed whole organism vaccine?

Polio

MMR

Influenza

Rabies

Typhoid

23. Which does not happen following an exposure to an allergen?

Cross-linking of IgE

Rise in cAMP

Calcium influx

Migration of granules

Exocytosis

24. Which is true of Guellain-Barre syndrome?

Normal function rarely returns to patients.

The cause is overmyelination of nerve tissue and peripheral nerve monocyte tissue infiltrate

It occurs following infectiious disease such as measles, hepatitis and polio, or after vaccination for influenza

It effects the endocrine glands, especially lacrimal and salivary

Symptoms include fatigue and weight loss

25. The most prevalent autoimmune disorder in tne United States is:

Myasthenia gravis

Guillain-Barre

Systemic lupus erythematosus

Grave's disease

Sjogren's syndrome

26. Sjogren's syndrome

Results from faulty absorption fo vitamin B12

Affects endocrine glands, especially lacrimal and salivary

Involves destruction of the islets of Langerhaans

Involves an enlargd thymus in 60-80% of patients

Involves demyelination of nerve tissue and peripheral nerve monocyte tissue infiltrate

27. Which is false about myasthenia gravis?

80-90% of patients have antibodies against acetylcholine receptor

It is caused by depletion of acetylcholine receptors at the myoneural junction

Symptoms include weight gain, slow pulse, and thinning of hair

It is treated by anticholinesterase

There is a genetic disposition in human leukocyte antigen DR3

28. Which are disadvantages of live vaccines? (two answers

Organisms can multiply and produce infection, not disease

They can be transmitted to others

Immunity requires fewer shots

They can mutate back to the original strain

They offer long-term protection

Submit

29. Which is false concerning tests for type 1 hypersensitivity?

An ELISA analysis tests for total IgE

An mRAST is a radiometric test for allergen specific IgE

A wheal over 15mm in a skin test is +4

Symptoms occur within ten minutes of a skin test

A wheal and flare reaction is the goal of the skin test

30. Which is true about contact sensitivity?

People with contact sensitivity are most likely to be male and Asian.

60,000 Americans develop reactions to poison ivy or poison oak annually.

90% of workers compensation claims are for contact sensitivity reactions

15% of children show a reaction to one or more allergens on a skin test

31. What percentage of Sjogren's syndrome patients also suffer from rheumatoid arthritis?

10:%

25%

50%

75%

100%

32. Treatment for myasthenia gravis might include:

Metabolic control

Plasmapheresis

Synthetic thyroid hormones

Thymectomy

NSAIDS

33. Which of the following is false?

T cells that react with antigens are normally removed, made unresponsive or converted to a tolerogenic T helper cell

Antigens are usually sequestered

Epstein-Barr virus is linked to multiple sclerosis

Influenza and polio are related to Guellain-Barre

Signs include elevated IgG levels

34. Half of patients with systemic lupus erythematosus patients have involvement; the other half have _ involvement.

Lung...musculoskeletal

Renal...cardiovascular

Central nervous system...lung

Renal...central nervous system

Musculoskeletal...cardiovascular

35. Which attenuated vaccines are currently in development? (two answers)

AIDS

Salmonella

Cholera

SARS

Leishmania

Submit

36. Which is false?

Pasteur discovered microbes grown in unusual hosts lost their strength..

A Trojan horse vaccine uses a live pathogenic carrier to contain an antigenic determinant.

The host for pertussis vaccine is a hamster.

Adenovirus is often used as a Trojan horse.

Oc=ver-expressed proteins are used as vaccines in rDNA technology.

37. Which is false about Type IV hypersensitivity?

The reaction is often in the shape of the offending object.

It is an inflammatory allergy as opposed to a necrotic allergy.

Onset is generally 12-48 hours after exposure

T cells and macrophages are involved

Allergen sensitized cytotoxic CD8 T cells alter epithelia

38. Which is true?

The highest rates of asthma are in Peru, Chile, South Africa, and New Zealand

The incidence of asthma is rising 20 to 50 percent every 5 years

Treatment costs include $8.1 billion in direct cost and $4.6 billion in lost earnings

150 million suffer from asthma worldwide

IgE does not cause non-allergic rhinitis

39. 1 in 100,000 Americans have:

Grave's disease

Guillain-Bare

Myasthenia gravis

Hashimoto's thyroiditis

Pernicious anemia

40. This disease is often comorbid with thyroid problems

Type I diabetes

Sjogren's syndrome

Pernicious anemia

Systemic lupus erythematosus

Guellain Barre

41. Trojan horse vaccines in development include: (three answers)

Salmonella

Tuberculosis

Leprosy

AIDS

Haemophilis

Submit

42. Which is not an attenuated vaccine? (two answers)

Leprosy

MMR

Cholera

FluMist

Polio

Submit

43. Which is an example of a control inhaler? (two answers

Ventolin

Proventil

Flovent

Advair

Intal

Submit

44. Which of the following have associated weight loss? (three answers)

Rheumatoid arthritis

Hashimoto's thyroiditis

Grave's disease

Pernicious anemia

Myasthenia gravis

Submit

Immunology Self Test

1. How is contact sensitivity diagnosed?

2.

What first name or nickname would you like us to use?

2. Which is associated with a butterfly rash on nose and cheeks?

3. Which vaccines use microbes that were cultured in a way that made them lose their virulence?

4. Which of the following is an example of a toxoid vaccine?

5. Which of the following measures forced expiratory volume in one second?

6. Which results from underproduction of thyroxine?

7. Which of the following is a capsular vaccine? (two answers)

8. Which is false about type I diabetes?

9. Which is not an example of an antihistamine?

10. Which is false?

11. Which cancer is not associated with a oncogenic microbe?

12. Which is false about contact sensitivity?

13. Increased incidence of stomach cancer is seen in patients with:

14. Which is not an effective of histamine?

15. Which is not an effect of leukotrienes?

16. Which is false about Type I (allergic) hypersensitivity?

17. Ptosis is a sign of which of the following diseases?

18. Which vaccines use fragments or proteins of virulent microbes?

19. Autoimmune diseases

20. Which is an example of an anti-leukotriene?

21. Natural active immunity

22. Which is not a killed whole organism vaccine?

23. Which does not happen following an exposure to an allergen?

24. Which is true of Guellain-Barre syndrome?

25. The most prevalent autoimmune disorder in tne United States is:

26. Sjogren's syndrome

27. Which is false about myasthenia gravis?

28. Which are disadvantages of live vaccines? (two answers

29. Which is false concerning tests for type 1 hypersensitivity?

30. Which is true about contact sensitivity?

31. What percentage of Sjogren's syndrome patients also suffer from rheumatoid arthritis?

32. Treatment for myasthenia gravis might include:

33. Which of the following is false?

34. Half of patients with systemic lupus erythematosus patients have __ involvement; the other half have ___ involvement.

35. Which attenuated vaccines are currently in development? (two answers)

36. Which is false?

37. Which is false about Type IV hypersensitivity?

38. Which is true?

39. 1 in 100,000 Americans have:

40. This disease is often comorbid with thyroid problems

41. Trojan horse vaccines in development include: (three answers)

42. Which is not an attenuated vaccine? (two answers)

43. Which is an example of a control inhaler? (two answers

44. Which of the following have associated weight loss? (three answers)

34. Half of patients with systemic lupus erythematosus patients have involvement; the other half have _ involvement.