1.
What is a group of drugs that promote water loss from the body into urine, remove excess Extracellular fluid into interstitial tissue that could another wise result in edema?
Correct Answer
Diuretics
2.
Name the 5 classes of Diuretics?
Correct Answer
1) carbonic anhydrase inhibitors 2)osmotic 3) thiazide 4) loop direutics 5) potassium sparing diuretics
3.
Which class of diuretics stops the conversion of CO2 into carbonic acid & bicarbonate ions. stoping this enzyme will result from converting carbonic acid into CO2 and water ( which will be reabsorbed)
Correct Answer
B. Carbonic anhydrase inhibitors
4.
Which class of diuretics Prevents the reabsorption of sodium on the distal convoluted tubules and collecting ducts and increases excretion of chloride, potassium & bicarbonate ions . Used to treat hypertension as adjustive therapy in edema associated with heart failure and cirrohis.
Correct Answer
C. Thiazide
5.
Which class of direutics has a mechanism of action by blocking Sodium and cholrine symporter thats associated with luminal membrane, inhibts the sodium/cholrine reabsorption from distal convluted tubules in kidney
Correct Answer
C. Thiazide
6.
Which class of direutics decreases solute content resulting in less water reabsorption by the loop of henle and collecting duct- less sodium reabsorption in proximal tubule. highly effective in cerebral edema.
Correct Answer
A. Osmotic Direutics
7.
Which class of direutics act on the ascending loop of henle, it inhibts the Na K 2Cl symporter ( cotransporter) in the thick ascending limb of the loop of Henle to inhibt sodium and cholrine reabsorption. Used in pulmonary edema of heart failure, also used to treat hypercalcemia, hypertension.
Correct Answer
D. Loop direutics
8.
Which class of diuretics prevents sodium reabsorption in the distal tubule, treating edema of heart failure, hepatic cirrhosis with ascites, nephrotic syndrome.
Correct Answer
E. Potassium sparing Direutics
9.
Which drug is an example of a Loop Direutic?
Correct Answer
C. Furosemide ( lasix)
10.
Which drug is an example of a carbonic anhydrase inhibitor?
Correct Answer
A. Acetazolamide
11.
Which drug is an example of an osmotic diuretic?
Correct Answer
B. Mannitol
12.
Which drug is an example of a Potassium Sparing diuretics?
Correct Answer
D. Amiloride
13.
The direutics that act on the Proximal Convoluted Tubule is (are)
Correct Answer(s)
A. Mannitol
B. Acetazolamide
14.
The direutics that act on the Distal Convoluted Tubule is (are)
Correct Answer
C. Thiazide
15.
The diuretics that act on this ascending loop of Henle are (are)
Correct Answer
D. Furosemide
16.
The diuretics that act on the Collecting Duct is (are)
Correct Answer
E. Amiloride
17.
Which Hypertension drug blocks calcium, slows heart rate, reduces conduction irritability and dilates vessels
Correct Answer
D. Calcium channel blockers
18.
Which Hypertension drug blocks alpha 1 adrenergic receptors in arteries and smooth muscles, and can be used with thiazide diuretics
Correct Answer
B. Beta-blockers
19.
Which Hypertension drug blocks calcium, slows heart rate, reduces conduction irritability and dilates vessels
Correct Answer
D. Calcium channel blockers
20.
Which Hypertension drug produces direct relaxation of vascular smooth muscles, resulting in vasodilation/ Used with beta-blockers & diuretics
Correct Answer
C. Vasodilators
21.
Which Hypertension drug inhibts the Angiotensin-converting enzyeme, decreases formation of angiotensin II to lower blood volume and BP.
Correct Answer
E. ACE inhibitors
22.
Which Hypertension drug inhibits the binding of angiotensin II to angiotensin I receptors in vascula smooth muscles, blocking vasoconstriction & aldosterone secretion.
Correct Answer
F. Angiotensin-receptor blockers
23.
Name the Receptor that ARBs work on
Correct Answer
AT1 receptor
AT1
24.
Describe what the function of the AT1 receptor is?
25.
Describe what the function of the ACE receptor is?
26.
Kind of Beta Blocker drug?
Correct Answer(s)
A. Metoprolol ( lopressor)
B. Propranolol ( inderal)
27.
Kind of Calcium Channel blocker drug?
Correct Answer(s)
C. Nifedipine
D. Verapamil
28.
Kind of Angiotensin II receptor Blocker drug?
Correct Answer
E. Losartan
29.
Whats the condition called when the heart pumps at an insufficient rate, kidneys retain sodium and water and fluid accumulates in insterstital space
Correct Answer
Congestive Heart failure
congestive heart failure
30.
What do Cardiac glycosides do?
Correct Answer
They increase cell calcium concentration to enhance the contracitility of the cardiac muscles, used to relieve the symptoms of congestive heart failure
31.
What are some natural examples of Cardiac glycosides? Name three
Correct Answer
digoxin- derieved from foxglove ( purple flowering plant) and oleander, lily of the vally
32.
How do beta agonists improve CHF?
Correct Answer
Improve cardiac performance by inotropic effects and vasodialation
33.
How do Phosphodiesterase inhibtors improve CHF?
Correct Answer
Examples are amirionone and milrionone they increase force of heart contractions and cause vasodilation
34.
How do Direutics CHF?
Correct Answer
relieve pulmoonary congestion and peripheral edema by decreasing plasma volume