Hpmt 356- Immunology

60 Questions | Attempts: 192
Share
SettingsSettings
Please wait...
  • 1/60 Questions

    Name the correct antibody. Mediates hypersensitivity reactions

Please wait...
About This Quiz

Review quiz based on PPP for Microbiology Lecture 3- Immunology

Hpmt 356- Immunology - Quiz

Quiz Preview

  • 2. 

    Name the correct antibody. Produced early in immune response, large molecule

  • 3. 

    Name the correct antibody. Major Ig in normal serum, crosses placenta

  • 4. 

    This antibody is associated with immediate hypersensitivity such as allergy and anaphylaxis

  • 5. 

    B cells mature in the thymus and T cells mature in the bone marrow before release

    • True

    • False

    Correct Answer
    A. False
    Explanation
    B cells mature in bone marrow, and T cells mature in the thymus

    Rate this question:

  • 6. 

    Process in which particulate Antigen aggregates to form larger complexes in the presence of specific antibody

    Correct Answer
    agglutination
  • 7. 

    These are chemical messengers involved in all aspects of innate and adaptive immune response and includes Interferons, Chemokines, tissue necrosis factor, transforming growth factors and interleukins

    Correct Answer
    cytokines
  • 8. 

    Cytotoxic T cells search for infected cells and  either lyse the cells or cause

    Correct Answer
    apoptosis
  • 9. 

    Name the correct antibody. Predominant in Ig secretions

    Correct Answer
    IgA
  • 10. 

    Foreign substance capable of stimulating an immune response

    • Antigen

    • Antibody

    Correct Answer
    A. Antigen
  • 11. 

    Name the correct antibod. Surface of B Lymphs

    Correct Answer
    IgD
  • 12. 

    The antibody molecule is composed of two identical light chains and two identical heavy chains linked by disulfide bonds

    • True

    • False

    Correct Answer
    A. True
  • 13. 

    Anamnestic response/ memory response occurs after

    • Trauma

    • Repeated exposure to the same antigen

    • Taking medication

    • None of the above

    Correct Answer
    A. Repeated exposure to the same antigen
  • 14. 

    Antibodies are also known as

    Correct Answer
    immunoglobulins
  • 15. 

    Which of the following does immunology deal with

    • The study of molecules, cells organs and systems responsible for the recognition and disposal of nonself material

    • How body components respond and interact

    • Desirable or undesirable consequences of immune interactions

    • How the immune system can be manipulated to protect against or treat disease

    • All of the above

    Correct Answer
    A. All of the above
  • 16. 

    Which of the following is not apart of the first line of defense

    • Skin and mucous membranes

    • Normal flora

    • Secretions

    • Antibodies

    • Defensins

    Correct Answer
    A. Antibodies
  • 17. 

    An overactive immune response can lead to

    • SIRS - severe inflammatory response syndrome

    • Septic shock

    • Death

    • All of the above

    • None of the above

    Correct Answer
    A. All of the above
  • 18. 

    Complement is most closely association with

    • Promotion of opsonization and lysis of foreign cells

    • Detection of self from nonself

    • Detection of damaged tissue

    • None of the above

    Correct Answer
    A. Promotion of opsonization and lysis of foreign cells
  • 19. 

    Once complement has been activated, enzyme activation occurs

    • True

    • False

    Correct Answer
    A. True
  • 20. 

    Complement received its name because it complements the action of antibodies

    • True

    • False

    Correct Answer
    A. True
  • 21. 

    Innate immunity is required for initiation of adaptive response

    • True

    • False

    Correct Answer
    A. True
  • 22. 

    Activates cascade

    • Agglutination

    • Neutralization

    • Opsonization

    • Complement activation

    Correct Answer
    A. Complement activation
  • 23. 

    Recognition, remembrance and response to a specific stimulus or antigen is not a part of

    • Specific/adaptive immunity

    • 3rd line of defense

    • Innate or inborn resistance

    • Cell mediated immunity

    • Humoral immunity

    Correct Answer
    A. Innate or inborn resistance
  • 24. 

    Acute phase reactant response is associated with

    • Increase in concentration of some proteins during inflammation

    • Disposal of waste

    • Opsonization

    • None of the above

    Correct Answer
    A. Increase in concentration of some proteins during inflammation
  • 25. 

    Promotion of phagocytosis

    • Agglutination

    • Neutralization

    • Opsonization

    • Complement activation

    Correct Answer
    A. Opsonization
  • 26. 

    Which of the following is not a phase of the  primary antibody response

    • Lag phase

    • Plateau phase

    • Log phase

    • Decline phase

    • Competitive phase

    Correct Answer
    A. Competitive phase
  • 27. 

    Humoral immunity describes fluids that defend the body from microbial attack

    • True

    • False

    Correct Answer
    A. True
  • 28. 

    The classical pathway of complement activation is triggered by

    • Allergen, foreign substance, or lipopolysaccharide

    • Mannose on cell surface

    • Antigen/ antibody

    • All of the above

    • None of the above

    Correct Answer
    A. Antigen/ antibody
  • 29. 

    The three pathways of complement activation converge

    • Cleavage of C5 to C5b

    • Cleavage of C3 to C3b

    • Cleavage of Membrane attack complex

    • None of the above

    Correct Answer
    A. Cleavage of C3 to C3b
  • 30. 

    Adequate Ag and Ab available- optimal precipitation, see large visible complexes

    • Zone of antigent excess (Post zone)

    • Zone of equivalence

    • Zone of antibody excess(prozone)

    • None of the above

    Correct Answer
    A. Zone of equivalence
  • 31. 

    The secondary (Anamnestic) response has the same 4 phases as the primary response and come with repeated exposure

    • True

    • False

    Correct Answer
    A. True
  • 32. 

    T cells respond directly to antigens or proteins

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Need antigen presenting cells with antigen in MHC

    Rate this question:

  • 33. 

    Not enough Antigen present to form precipitate- results in soluble complexes

    • Zone of antigent excess (Post zone)

    • Zone of equivalence

    • Zone of antibody excess(prozone)

    • None of the above

    Correct Answer
    A. Zone of antibody excess(prozone)
  • 34. 

    Concerning antigen presenting cells, which statement is true

    • Macrophages and dendritic cells present to T cells

    • T cells present to macrophages and dendritic cells

    • Macrophages present to dendritic and T cells

    • Dendritic cells present to macrophages and T cells

    • None of the above

    Correct Answer
    A. Macrophages and dendritic cells present to T cells
  • 35. 

    Booster shots are a combination of primary and secondary response

    • True

    • False

    Correct Answer
    A. True
  • 36. 

    This cell, under the stimulation of a Thelper cell, returns to the bone marrow to mature

    • Pro-b cell

    • Immature b cell

    • Mature b cell

    • Plasma cell

    Correct Answer
    A. Immature b cell
  • 37. 

    Which does not describe antibodies/ immunoglobulins

    • Found in blood plasma and some body fluids

    • May need other agents like complement for bacteria

    • Includes IgM, IgG, IgA, IgD and IgE

    • Made of 2 heavy chains and 4 light chains with a variable and constant region

    • None of the above

    Correct Answer
    A. Made of 2 heavy chains and 4 light chains with a variable and constant region
    Explanation
    made of 2 light chains and 2 heavy chains

    Rate this question:

  • 38. 

    Double negative thymocytes (DN) cells show no expression of CD4 or CD8 or TCR. These cells however go on to differentiate into CD4, CD8 and Natural Killer NK cells. Regarding this process, which of the following is not true.

    • CD8 cells must have partial recognition of MHC class I

    • Nk have expression of CD4 but not CD8

    • CD4 cells must have recognition of MHC class II

    • Must recognize self

    Correct Answer
    A. Nk have expression of CD4 but not CD8
    Explanation
    NK cells show no expression of CD4 or CD8

    Rate this question:

  • 39. 

    Prevent microbial attachment to host

    • Agglutination

    • Opsonization

    • Neutralization

    • Complement activation

    Correct Answer
    A. Neutralization
  • 40. 

    Which of the following would not be considered active humoral immunity

    • Natural exposure to pathogen

    • Given serum or plasma with high concentration of preformed antibody

    • Vaccination

    • Host makes antibodies

    Correct Answer
    A. Given serum or plasma with high concentration of preformed antibody
    Explanation
    when the antibodies are acquired from an outside source it provides passive immunity which is immediate but temporary

    Rate this question:

  • 41. 

    Adaptive immunity is the ______line of defense

    • 1st

    • 2nd

    • 3rd

    Correct Answer
    A. 3rd
  • 42. 

    Antigenic binding portion of the antibody

    • Fab and Fc regions

    • 2 heavy chains

    • 2 light chains

    • Variable region

    • Constant region

    Correct Answer
    A. Variable region
  • 43. 

    Crosslinkages of antigen-antibody compleses are reversible

    • True

    • False

    Correct Answer
    A. True
  • 44. 

    Pattern recognitions receptors on cell membranes of phagocytic and other mammalian cells allow them to identify foreign cells. Which of the following is not a pattern recognition receptor

    • Toll-like receptor

    • Protein kinase r

    • Mannose receptor

    • Epitope

    • CD14

    Correct Answer
    A. Epitope
    Explanation
    epitope is a part of an antigen/ antigen determinant

    Rate this question:

  • 45. 

    Which is not true about the  Mannose binding lectin pathway

    • Associated with MASP1 and MASP 2 protease

    • Activated by antigens/antibodies

    • Initiated by binding with mannose groups on bacterial cell surfaces

    • All of the above

    • None of the above

    Correct Answer
    A. Activated by antigens/antibodies
  • 46. 

    Complement is present in circulation in active form but can be inhibited by control proteins

    • True

    • False

    Correct Answer
    A. False
    Explanation
    complement circulates in inactive form and control proteins inhibit automatic activation

    Rate this question:

  • 47. 

    The alternate pathway of complement activation is triggered by

    • Contact with foreign surface

    • Antigen/antibody

    • Mannose

    • All of the above

    • None of the above

    Correct Answer
    A. Contact with foreign surface
  • 48. 

    The final stage of humoral immunity that features the attack of cells and their destruction without engulfing

    • Opsonization

    • Antibody-dependent cell mediated toxicity

    • Complement activation

    • Neutralization

    Correct Answer
    A. Antibody-dependent cell mediated toxicity
  • 49. 

    Delayed type hypersensitivity is mediated by CD4+ cells and features interaction between phagocytic cells and T lymphocytes. which of the following would not be considered a delayed type hypersensitivity

    • Slow appearance of secondary response in the skin

    • PPD

    • Rash from Poison Ivy

    • Allergy

    • Granulomas from M. Tuberculosis

    Correct Answer
    A. Allergy

Quiz Review Timeline (Updated): Oct 18, 2018 +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Oct 18, 2018
    Quiz Edited by
    ProProfs Editorial Team
  • Sep 27, 2010
    Quiz Created by
    Chinedua
Back to Top Back to top
Advertisement
×

Wait!
Here's an interesting quiz for you.

We have other quizzes matching your interest.