Master Architects of the Early Renaissance in Florence

Brunelleschi is the correct answer as he was the architect responsible for designing the Old Sacristy in San Lorenzo, Florence during the specified timeframe. Michelangelo, Leonardo da Vinci, and Raphael were renowned artists and geniuses in their own right, but they were not the architects behind this specific project.

Brunelleschi was the architect responsible for the design and construction of the iconic Florence Cathedral Dome, completing it over a span of 16 years. While Leonardo da Vinci, Michelangelo, and Raphael are also renowned Italian artists from the Renaissance period, they were not specifically attributed to the design of the Florence Cathedral Dome.

Brunelleschi was the architect responsible for the design and construction of the Ospedale Degli Innocenti in Florence during the stated time frame, showcasing his innovative approach to classical architecture.

Although Michelangelo, Leonardo da Vinci, and Raphael were all renowned Italian artists during the Renaissance period, it was Filippo Brunelleschi who was the architect behind the San Lorenzo church in Florence in 1421. Known for his innovative architectural designs and engineering skills, Brunelleschi's work on the church is considered one of his notable achievements.

Although Donatello, Michelangelo, and Leonardo da Vinci were all famous Italian artists during the Renaissance period, none of them were the architect of Santo Spirito in Florence. It was actually Filippo Brunelleschi who designed the church.