Explain Gi Pathology Terms Quiz

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1. Why is melena a sign of upper GI bleed?

Explanation

Melena is a result of acid in the stomach converting hemoglobin to hematin, not caused by trauma to the lower intestinal tract, a deficiency in vitamin C, or excess bile production in the liver.

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About This Quiz
Explain GI Pathology Terms Quiz - Quiz

This educational tool focuses on the terminology used in gastrointestinal pathology, assessing key skills in identifying and understanding specific pathological conditions affecting the gastrointestinal tract. It is designed... see morefor medical students and professionals to enhance diagnostic accuracy and patient care. see less

2. When would a patient with internal hemorrhoids experience pain?

Explanation

Internal hemorrhoids are mostly painless, but thrombosis can cause pain. Other activities like defecation, vomiting, and coughing do not specifically trigger pain in internal hemorrhoids.

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3. Patient with new onset jaundice + Epigastric tenderness. CT scan shows a mass in head of the pancreas. Aspiration reveals anaplastic cells. These anaplastic cells most likely originated from which part of the pancreas?

Explanation

Anaplastic cells in the pancreas most likely originate from the DUCTAL Epithelium, as majority of pancreatic cancers arise from this part. Acinar Cells, Islets of Langerhans, and Connective Tissue are less likely origins for anaplastic cells in this context.

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4. Which condition presents with fever, right lower quadrant pain with rebound tenderness in the RIGHT lower quadrant, and neutrophilic leukocytosis but is not appendicitis?

Explanation

Acute Meckel's diverticulitis can mimic appendicitis due to its location and symptoms. It is a true diverticulum that results from the failure of the viteline duct to obliterate during development.

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5. A chronic alcoholic presents with epigastric pain radiating to the back and pleural effusion. What lab value is most specific for this condition? Why might the patient have hyperglycemia? What happens to calcium levels in the blood?

Explanation

Increased Serum Lipase is a more specific marker for acute pancreatitis compared to Serum Amylase. Pleural effusion in this context is likely due to the inflammatory response in the pancreas, not an allergic reaction in the lungs. Hyperglycemia in acute pancreatitis is primarily due to the destruction of beta-islet cells in the pancreas, not excessive sugar intake. Hypocalcemia is a consequence of enzymatic fat necrosis, not a direct result of other conditions.

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6. Most common site of origin of carcinoid tumor vs most likely site of origin in a patient with Pansystolic murmur at tricuspid area, which gets louder with Inspiration, who has elevated 5-HIAA levels in his urine?

Explanation

While the appendix is the most common site of origin for carcinoid tumors, in a patient presenting with symptoms of Carcinoid Syndrome, such as a pansystolic murmur at the tricuspid area, the most likely site of origin would be the TERMINAL ILEUM due to the unique characteristics and metastatic patterns of carcinoids in this context.

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7. What is a major pathophysiologic mechanism for pancreatitis?

Explanation

Pancreatitis is primarily caused by inappropriate activation of pancreatic enzymes due to various reasons such as pancreatic duct/ampullarobstruction, chronic alcohol consumption, acinar cell damage, or infections. It is not directly linked to high cholesterol levels, lack of exercise, or excessive sugar consumption.

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8. What is Menetrier's disease characterized by?
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9. A painless mass in the parotid area. Histologic exam reveals mucinous and squamous components. Is this salivary gland mass likely benign or malignant?

Explanation

The presence of mucinous and squamous components in the histologic exam suggests a mucoepidermoid carcinoma, the most common malignant tumor of the salivary gland. Benign mixed tumor (pleomorphic adenoma), acinic cell carcinoma, and Warthin tumor are benign salivary gland tumors with different histological features.

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10. A painless, mobile mass was excised and recurred. Histology reveals chondromyxoid stroma and epithelium. Is this tumor most likely benign or malignant?

Explanation

Pleomorphic adenoma is a benign salivary gland tumor characterized by chondromyxoid stroma and epithelium. It is known to recur after excision, hence the importance of correct identification.

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11. What is the most common tumor of salivary glands overall and what is the most common MALIGNANT salivary gland tumor?

Explanation

Pleomorphic adenoma is the most common tumor of salivary glands overall, while Mucoepidermoid Carcinoma is the most common malignant salivary gland tumor. The other options are incorrect as they do not represent the most common tumors in the given context.

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12. Patient with painless mass in ____ region develops paralysis of facial muscles....MOST likely salivary gland involved?Most likely nerve involved, does this nerve innervate this gland?Is this mass most likely gland/malignant?

Explanation

This question highlights the importance of understanding the location of salivary gland tumors, the involvement of the facial nerve, and the potential for malignancy. The correct answer emphasizes the significance of the parotid region, the lack of direct innervation of the parotid gland by the facial nerve, and the likelihood of benign tumors with malignant potential.

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13. How can Trypanosoma Cruzzi infection in South/Central America increase the risk of Esophageal cancer, especially Squamous Cell Carcinoma (SCC)?
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14. What is the difference between Dysphagia of solids and liquids vs Dysphagia to solids?

Explanation

Dysphagia of solids and liquids usually points towards a condition like Achalasia where there is difficulty in swallowing both solids and liquids. On the other hand, Dysphagia to solids typically indicates a physical obstruction like Esophageal Cancer which can initially cause trouble with solid foods before progressing to liquids as well.

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15. What is the cause of post-cricoid dysphagia in patients with Plummer Vinson syndrome? What are some characteristic findings? For which cancer are these patients at increased risk?

Explanation

Plummer Vinson syndrome is characterized by esophageal webs, glossitis, and koilonychia. These patients are at increased risk of squamous cell carcinoma due to chronic irritation and inflammation of the esophagus.

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16. What pathologic findings are you likely to see in the esophagus due to decreased LES tone in Scleroderma?

Explanation

In Scleroderma, the decreased LES tone leads to acid reflux causing intestinal metaplasia (Barrett esophagus) due to atrophy of smooth muscle layer in the esophagus.

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17. Patient with Pyrosis(Heartburn),ADULT onset asthma and chronic cough, now starts to complain of hoarseness...

Explanation

The correct answer explains that the hoarseness is caused by LARYNGOPHARYNGEAL reflux associated with GERD, not by allergic rhinitis, acute laryngitis, or vocal cord nodules. GERD leads to various complications like Barett esophagus and adenocarcinoma.

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18. Patient with allergies and GERD unresponsive to therapy....You are worried about impaction of food (food getting stuck in the esophagus) Endoscopy shows 'Trachealization' of esophagus - rings in the esophagus...what will the biopsy of esophagus likely show?

Explanation

The correct answer is A) Presence of H. pylori bacteria in the esophagus. In the given scenario, the presence of 'Trachealization' of esophagus and unresponsiveness to therapy points towards EOSINOPHILIC esophagitis causing food impaction. This condition is characterized by infiltration of eosinophils in the esophagus, not the other conditions mentioned in the incorrect answers.

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19. How can HSV1 esophagitis, CMV esophagitis, and Candida Esophagitis be differentiated?
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20. Which antibiotic is famous for causing esophagitis?

Explanation

Tetracyclines are known to cause esophagitis due to their mechanism of action.

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21. What should you think about in a patient with a partial thickness laceration of mucosa at the GASTROESOPHAGEAL junction presenting with hematemesis?

Explanation

The key features of Mallory-Weiss syndrome include a longitudinal laceration at the Gastroesophageal junction, painful hematemesis, and a rapid increase in intraabdominal pressure (such as during retching). This differentiates it from Esophageal varices, which typically result in painless hematemesis and are due to portal hypertension. Peptic ulcer disease and Gastric cancer may also present with hematemesis but do not typically involve a partial thickness laceration at the Gastroesophageal junction.

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22. Alcohol vs Cigarette smoking...predisposition to cancer of Esophagus...

Explanation

The correct answer highlights the specific types of esophageal cancer that alcohol and cigarette smoking predispose individuals to. Alcohol is associated with Squamous Cell Carcinoma (SCC), while Cigarette smoking is linked with Adenocarcinoma of the esophagus and to SCC of Esophagus.

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23. Obesity is a risk factor for which type of esophageal cancer?

Explanation

Obesity is a known risk factor for developing adenocarcinoma of the esophagus, whereas the other types listed are not typically associated with obesity.

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24. Ingestion of strong acids/bases(Caustic strictures), Hot fluids predispose you to which type of esophageal cancer?

Explanation

The correct answer is SCC of Esophagus because exposure to strong acids/bases and hot fluids can lead to squamous cell carcinoma (SCC) of the esophagus due to chronic irritation and tissue damage. Adenocarcinoma of Esophagus is more commonly associated with gastroesophageal reflux disease (GERD) and Barrett's esophagus. Gastric Cancer primarily affects the stomach, not the esophagus. Lung Cancer is associated with tobacco smoking and exposure to asbestos, not ingestion of strong acids/bases or hot fluids.

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25. What are the differences between acute and chronic gastritis?

Explanation

Acute gastritis is characterized by erosion of the mucosa's epithelium, while chronic gastritis involves ulcers that penetrate deeper layers. The incorrect answers provide inaccurate information regarding the differences between acute and chronic gastritis.

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Why is melena a sign of upper GI bleed?
When would a patient with internal hemorrhoids experience pain?
Patient with new onset jaundice + Epigastric tenderness. CT scan shows...
Which condition presents with fever, right lower quadrant pain with...
A chronic alcoholic presents with epigastric pain radiating to the...
Most common site of origin of carcinoid tumor vs most likely site of...
What is a major pathophysiologic mechanism for pancreatitis?
What is Menetrier's disease characterized by?
A painless mass in the parotid area. Histologic exam reveals mucinous...
A painless, mobile mass was excised and recurred. Histology reveals...
What is the most common tumor of salivary glands overall and what is...
Patient with painless mass in ____ region develops paralysis of facial...
How can Trypanosoma Cruzzi infection in South/Central America increase...
What is the difference between Dysphagia of solids and liquids vs...
What is the cause of post-cricoid dysphagia in patients with Plummer...
What pathologic findings are you likely to see in the esophagus due to...
Patient with Pyrosis(Heartburn),ADULT onset asthma and chronic cough,...
Patient with allergies and GERD unresponsive to therapy....You are...
How can HSV1 esophagitis, CMV esophagitis, and Candida Esophagitis be...
Which antibiotic is famous for causing esophagitis?
What should you think about in a patient with a partial thickness...
Alcohol vs Cigarette smoking...predisposition to cancer of...
Obesity is a risk factor for which type of esophageal cancer?
Ingestion of strong acids/bases(Caustic strictures), Hot fluids...
What are the differences between acute and chronic gastritis?
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