Mesohyl is the gelatinous, protein-rich matrix between the outer pinacoderm and inner choanoderm. It houses various cells, including amoebocytes, sclerocytes, and reproductive cells. The mesohyl acts as connective tissue, providing structure, storing nutrients, and facilitating cellular transport. It is not a water canal or reproductive sac. Its function is closer to that of connective tissue in other animals, making it a key part of sponge physiology.