Exam 3 4 Lectures
- 1.The tuberculin skin test measures DTH to a purified protein derivative (PPD) of tuberculin. With reference to this test
- A.
A negative PPD test can be obtained from an individual who had a primary infection 20 years ago
- B.
A positive PPD indicates that the individual has active tuberculosis
- C.
A positive PPD cannot be obtained from an individual who had a primary infection twenty years ago
- D.
A positive PPD can be obtained within 24 hours after an inidivudal is infected with M. Tuberuclosis
- E.
A negative PPD test in an individual with AIDS show the patient is not infected with M. tuberculosis
- 2.Which of the following is a false statement about reactivation TB?
- A.
Tubercle bacilli can remain viable for long periods of time and be casual agents of reactivation
- B.
It is associated with immunosuppression due to malnutrition, alchool, age, and puberty
- C.
The primary infection can merge into the reactivation type
- D.
The chronic fever and weight loss may be mediated by macrophage derived TNF
- E.
The majority of individuals succumb to reactivation TB
- 3.Which of the following statements is false regarding Mycobacterium tuberculosis and tb?
- A.
Humans have a high innate immunity to M. Tuberculosis
- B.
Less than 10 bacilli can initiate a pulmonary infection in suceptible individuals
- C.
A animal variant (m. bovis) found in cows can cause tuberculosis in humans
- D.
Spread of M. tuberculosis outside of the lung has no serious clinical manifestations
- E.
Because of the high lipid content of the cell wall, once stained M. tuberculosis cannot be easily distained
- 4.In which of the following would penicillin be the treament of choice (assuming no resistance)
- A.
Treponema pallidium
- B.
Mycoplasma pneumoniae
- C.
Mycoplasma hominins
- D.
Ureaplasma urealyticum
- 5.Mycoplasma pneumoniae infection can be diagnosed by
- A.
The celar distinction of its clinical manifestations relative to those of bacterail and viral infections
- B.
The rapid growht of cultures from throat swabs or sputum
- C.
The presence of low titer cold hemagglutinins
- D.
The rise in serum antibody, detected by compliment fixation
- E.
Demonstration of urease activity
- 6.In the lab, what is the distinguishing feature of mycolplasma hominins?
- A.
Serolgical tests such as complement fixation
- B.
Arginine break down
- C.
Urease production
- D.
Fried Egg Colonies
- 7.All of the following statmenets concering Mycoplasma pneumonia are true except
- A.
It can be treated with erythormycin or tetracycline
- B.
It sometimes is called walking pneumonia
- C.
Predilection for an older individual
- D.
Pneumonia is usually less severe than other bacterial pneumonia
- E.
Accumulation of metabolites causes cytopathic effects
- 8.Rickettsia prowazekii
- A.
Causes endemic typhus
- B.
Replicates in endothelial cells
- C.
Is transmitted from birds to humans by mosquitoes
- D.
Exists in two different morphologic forms
- E.
Causes ornithosis
- 9.Rickettsia prowazekii
- A.
Causes epidemic typhus
- B.
Replicates in columnar epithelial cells
- C.
Is transmitted from birds to humans by mosquitoes
- D.
Exists as two different morphologic forms
- E.
Causes ornithosis
- 10.R. Rickettsi
- A.
Causes rocky mountain spotted fever
- B.
Causes epidemic typhus
- C.
Causes endemic typhus
- D.
Is transmitted from birds to humans by mosquitos
- E.
Causes ornithosis
- 11.C. Burnetti
- A.
Causes rocky mountain spotted fever
- B.
Causes epidemic typhus
- C.
Causes endemic typhus
- D.
Is transmitted from birds to humans by mosquitos
- E.
Causes Q fever
- 12.Which of the folowing causes Ornithosis?
- A.
C. psittaci
- B.
C. trachomatis
- C.
C. pneumonaie
- D.
R. rickettsil
- E.
R. prowazeki
- 13.Which of the following is the causitive agent for syphilis?
- A.
Treponema pallidium
- B.
Borrelia burgdorferi
- C.
M. Tuberculosis
- D.
M. avium
- E.
M. hominins
- 14.Which of the following is the causitive agent for lime disease?
- A.
Treponema pallidium
- B.
Borrelia burgdorferi
- C.
M. Tuberculosis
- D.
M. avium
- E.
M. hominins
- 15.Condylomata lata can occur as a result of an infection with
- A.
Treponema pallidium
- B.
Borrelia burgdorferi
- C.
M. Tuberculosis
- D.
M. avium
- E.
M. hominins
- 16.Which of the following is transmitted from rats to humans?
- A.
R. Typhi
- B.
R. rickettsil
- C.
R. prowazeki
- D.
Coxiella burnetti
- E.
C. pneumonaie
- 17.Infection with which one of the following organisms results in the generation of autoantibodies to heart muscle, probably resulting in atherosclerosis?
- A.
C. pneumoniae
- B.
C. psittaci
- C.
C. trachomatis
- D.
R. rickettsil
- E.
R. prowazeki
- 18.Which of the following statements concerning lyme disease is false?
- A.
It is primarily transmitted via ticks
- B.
It can later develop into chronic arthritis
- C.
Erythema migrans preffered treatment is doxycycline, although the definitive lab diagnosis involves an ELISA test and Western Blot analysis
- D.
It is not possible to develop a multi system infection from it
- E.
The primary treatment invovles doxycycline and amoxicilin
- 19.Which of the following causes blindness?
- A.
C. trachomatis (A-C)
- B.
C. trachomatis (D-K)
- C.
C. trachomatis (L)
- D.
C. Psittaci
- E.
C. Pneumonaie
- 20.The preferred threatment of the Ehrlichia species is
- A.
Doxycycline
- B.
Tetracycline
- C.
Chloramphnicol
- D.
Erythromycin
- E.
Oxfloaxin
- 21.Concerning C. trachomatis, which is incorrect?
- A.
C. trachomatis is a obligate intracellular parasite
- B.
C. trachomatis is found primarily in epithelial cells
- C.
C. trachomatus is detected via specific foulurescence - conjugate antibodies
- D.
C. trachomatis is tested for using ELISA and PCR
- E.
C. trachomatis is tested for using iodine staining
- 22.Which of the following is associated with Brill's disease?
- A.
R. prowazekii
- B.
R. rickettsil
- C.
R. typhi
- D.
Coxiella burnetti
- E.
C. psittaci
- 23.All of the following are traits of mycoplasma pneumonia except
- A.
The bacteria adheres via P1 to sialic acid residues on epithelia cells
- B.
It inhibits catalase, leading to a increase in H2O2
- C.
Itt causes alpha hemolysis on a plate of sheep blood
- D.
It is treated by tetracycline or erythromycin
- 24.Concerining mycoplasma hominins, which statement is false?
- A.
It is sensitive to tetracycline and reistant to erythormycin
- B.
It inhabits the GI tract
- C.
It is a opporutnistic organism
- D.
It is broken down by urease
- 25.Mycobacterium leprae is the causal agent for leprosy. Which statement is correct?
- A.
Two disease forms of leprosy are recognized, tuberculoid and lepromatous
- B.
The incubation period for leprosy is usually less than 6 months
- C.
Using a skin test based on DTH to lepromin, tuberculoid cases are negative and lepromatous cases are positive
- D.
In tuberculoid leprosy, CMI is defiient, nad growth of M. leprae is unimpeded
- E.
There are a estimated 100 thousand people infected with M. leprae in asia, africa, and latin america
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