Cytology: Thyroid And Hypothyroidism

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  • 1/32 Questions

    Select the correct statement about Thyroid gland anatomy.

    • Bilobed, caudal to larynx, adjacent to trachea
    • Bilobed, cranial to larynx
    • Bilobed, caudal to pharynx, adjacent to trachea
    • Bilobed, cranial to larynx, opposing the trachea
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About This Quiz

This quiz on 'Cytology: Thyroid and Hypothyroidism' explores the anatomy and function of the thyroid gland, including its hormone production and impact on metabolism. It assesses understanding of hypothyroidism, particularly its prevalence in dogs, enhancing both academic knowledge and practical insight.

Cytology: Thyroid And Hypothyroidism - Quiz

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  • 2. 

    The term "Thyroid nodule" is used to describe......

    • An enlarged thyroid gland

    • Nodules developing around the thyroid gland

    • Nodules developing around the trachea

    • An enlarged Parathyroid gland

    Correct Answer
    A. An enlarged thyroid gland
    Explanation
    The term "Thyroid nodule" is used to describe an enlarged thyroid gland. Thyroid nodules are abnormal growths or lumps that form in the thyroid gland, which is located in the front of the neck. These nodules can be solid or fluid-filled and are usually benign, although some may be cancerous. The enlargement of the thyroid gland can cause various symptoms such as difficulty swallowing, hoarseness, or a visible lump in the neck. It is important to evaluate and monitor thyroid nodules to determine if any further treatment or intervention is necessary.

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  • 3. 

    What are T3 and T4?

    • The two hormones produced by the thyroid gland

    • Thoracic vertebrae 3 and 4

    • The two hormones produced by the parathyroid gland

    • Tax return forms

    Correct Answer
    A. The two hormones produced by the thyroid gland
    Explanation
    I hope you did your taxes before finals.

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  • 4. 

    T3 and T4 regulate the rate of metabolism of....

    • Protein, carbohydrates and fats

    • Protein and fats

    • Protein and carbohydrates

    • Carbohydrates

    Correct Answer
    A. Protein, carbohydrates and fats
    Explanation
    T3 and T4 are hormones produced by the thyroid gland that play a crucial role in regulating metabolism. These hormones are responsible for controlling the rate at which the body breaks down and utilizes proteins, carbohydrates, and fats for energy. Therefore, the correct answer is "Protein, carbohydrates, and fats" as T3 and T4 regulate the metabolism of all three macronutrients.

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  • 5. 

    _______ is the decrease of thyroid hormone production, which leads to  ______ rate of metabolism. 

    • Hypothyroidism, decreased

    • Hyperthyroidism, decreased

    • Hypothyroidism, increased

    • Hyperthyroidism, increased

    Correct Answer
    A. Hypothyroidism, decreased
    Explanation
    Hypothyroidism is a condition characterized by a decrease in thyroid hormone production. Thyroid hormones play a crucial role in regulating metabolism, so a decrease in their production would result in a decreased rate of metabolism.

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  • 6. 

    Hypothyroidism is most common in ____.

    • Dogs

    • Cats

    • Lizards

    • Dragons

    Correct Answer
    A. Dogs
    Explanation
    It's called Smaug's disease in dragons. In case you were wondering. You win bonus points if you get the reference.

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  • 7. 

    _______ is the increase in thyroid hormone production, which leads to ______ rate of metabolism.

    • Hyperthyroidism, increased

    • Hyperthyroidism, decreased

    • Hypothyroidism, increased

    • Hypothyroidism, increased

    Correct Answer
    A. Hyperthyroidism, increased
    Explanation
    Hyperthyroidism is a condition characterized by excessive production of thyroid hormones by the thyroid gland. These hormones play a crucial role in regulating metabolism. When there is an increase in thyroid hormone production, it leads to an increased rate of metabolism. This means that the body's processes, such as digestion and energy expenditure, speed up. Therefore, the correct answer is Hyperthyroidism, increased.

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  • 8. 

    Hyperthyroidism is most common in _____.

    • Cats

    • Dogs

    • Horses

    • Martians

    Correct Answer
    A. Cats
    Explanation
    Ever heard of Red Planet disease? No? Maybe you should visit Mars and be more educated.

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  • 9. 

    What is the function of Calcitonin?

    • Maintaining blood calcium levels

    • Maintaining calcium storage in the bones

    • Decreasing bone formation and increasing bone breakdown

    • Calcium excretion

    Correct Answer
    A. Maintaining blood calcium levels
    Explanation
    Calcitonin is a hormone secreted by the thyroid gland that plays a crucial role in maintaining blood calcium levels. It helps to regulate calcium levels by inhibiting the release of calcium from bones into the bloodstream and promoting the excretion of calcium by the kidneys. This hormone works in opposition to parathyroid hormone, which increases blood calcium levels. By maintaining blood calcium levels within a narrow range, calcitonin ensures proper functioning of various physiological processes, including nerve transmission, muscle contraction, and bone health.

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  • 10. 

    Calcitonin ________ bone formation and _______ bone breakdown. This decreases the level of Calcium in the bloodstream.

    • Increases, decreaaes

    • Decreases, increases

    • Initiates, inhibits

    • Inhibits, initiates

    Correct Answer
    A. Increases, decreaaes
    Explanation
    Calcitonin is a hormone that regulates calcium levels in the bloodstream. It works by increasing bone formation, which means that it promotes the deposition of calcium into the bones. At the same time, calcitonin inhibits bone breakdown, which prevents the release of calcium from the bones into the bloodstream. By increasing bone formation and decreasing bone breakdown, calcitonin helps to decrease the level of calcium in the bloodstream.

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  • 11. 

    The _____ system is a coordinated response of the ________.

    • Negative feedback, hypothalmic-pituitary-thyroid axis

    • Positive feedback, hypothalmic-pituitary-thyroid axis

    • Negative feedback, hypothalmic pituitary axis

    • World domination, axis of evil

    Correct Answer
    A. Negative feedback, hypothalmic-pituitary-thyroid axis
    Explanation
    The correct answer is Negative feedback, hypothalmic-pituitary-thyroid axis. This is because negative feedback is a regulatory mechanism in which the output of a system inhibits or reverses the original stimulus, maintaining homeostasis. The hypothalmic-pituitary-thyroid axis is a hormonal pathway that regulates the production and release of thyroid hormones, which play a crucial role in metabolism and growth. Together, negative feedback and the hypothalmic-pituitary-thyroid axis work in coordination to maintain the balance of thyroid hormone levels in the body.

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  • 12. 

    TRH stands for...

    • Thyrotropin-Releasing Hormone

    • Thyroid Releasing Hormone

    • Trust Ron and Hermione (I'm talking to YOU Harry. You foolish adolescent.)

    • T4 Rules all Hormones (And T3 is a loser)

    Correct Answer
    A. Thyrotropin-Releasing Hormone
    Explanation
    The correct answer is Thyrotropin-Releasing Hormone. This hormone is responsible for stimulating the release of thyroid-stimulating hormone (TSH) from the pituitary gland. TSH then acts on the thyroid gland to promote the production and release of thyroid hormones, which play a crucial role in regulating metabolism and growth.

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  • 13. 

    TRH binds to cells in the _______ which stimulate the release of _____.

    • Pituitary, TSH

    • Thyroid, TSH

    • Hypothalamus, TSH

    • Prison, all the angry prisoners

    Correct Answer
    A. Pituitary, TSH
    Explanation
    Because there are lots of cells in a prison.

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  • 14. 

    TSH stimulates _______ synthesis and secretion.

    • Thyroid hormone

    • TRH

    • GnRh

    • DNA

    Correct Answer
    A. Thyroid hormone
    Explanation
    TSH (thyroid-stimulating hormone) stimulates the synthesis and secretion of thyroid hormone. Thyroid hormone is produced by the thyroid gland and plays a crucial role in regulating metabolism, growth, and development in the body. TSH acts on the thyroid gland to promote the production and release of thyroid hormone, which then acts on various tissues and organs to maintain proper functioning.

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  • 15. 

    Why do thyroid hormones do to TRH?

    • They inhibit its release

    • They trigger its synthesis and secretion

    • They trigger its synthesis

    • They occasionally give TRH a time-out when it misbehaves

    Correct Answer
    A. They inhibit its release
    Explanation
    That one time when TRH trolled the optic nerve so hard he basically rage quit....(TRH was grounded for 3 months)

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  • 16. 

    Select the correct statement about the negative feedback system.

    • TRH released -> TSH released -> T3/T4 secreted -> T3/T4 inhibit TRH

    • TSH released -> TRH released -> T3/T4 secreted -> T3/T4 inhibit TSH

    • TRH released -> T3/T4 secreted -> TSH released -> T3/T4 inhibit TSH

    • It will never get far in life because negativity only brings you down.

    Correct Answer
    A. TRH released -> TSH released -> T3/T4 secreted -> T3/T4 inhibit TRH
    Explanation
    The correct statement about the negative feedback system is that TRH is released, which then stimulates the release of TSH. TSH in turn stimulates the secretion of T3/T4 hormones. Finally, T3/T4 hormones inhibit the release of TRH. This negative feedback loop helps regulate the levels of T3/T4 hormones in the body, maintaining homeostasis.

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  • 17. 

    95% of Hypothyroidism are due to ____.

    • Destruction of the thyroid gland

    • Thyroid nodules

    • TRH inhibition

    • TSH inhibition

    Correct Answer
    A. Destruction of the thyroid gland
    Explanation
    Hypothyroidism is a condition characterized by an underactive thyroid gland, leading to a decrease in the production of thyroid hormones. The most common cause of hypothyroidism is the destruction of the thyroid gland. This can occur due to various reasons such as autoimmune diseases like Hashimoto's thyroiditis, where the immune system mistakenly attacks and damages the thyroid gland. Other causes include radiation therapy, surgical removal of the thyroid gland, or certain medications. Destruction of the thyroid gland accounts for approximately 95% of cases of hypothyroidism.

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  • 18. 

    Lymphoctic thyroidis and idiopathic atrophy of the thyroid gland lead to ____.

    • Hypothyroidism

    • Hyperthyroidism

    • Thyroiditis

    • Thyroid cancer

    Correct Answer
    A. Hypothyroidism
    Explanation
    Lymphocytic thyroiditis and idiopathic atrophy of the thyroid gland are both conditions that can cause damage to the thyroid gland. This damage can result in a decrease in the production of thyroid hormones, leading to hypothyroidism. Hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormones to meet the body's needs. This can result in symptoms such as fatigue, weight gain, and cold intolerance. Therefore, it is logical to conclude that lymphocytic thyroiditis and idiopathic atrophy of the thyroid gland can lead to hypothyroidism.

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  • 19. 

    Destruction of the thyroid causes ________, while damage to the pituitary tumor could lead to _______.

    • Primary hypothyroidism, secondary hypothyroidism

    • Primary hyperthyroidism, secondary hyperthyroidism

    • Primary hyperthyroidism, secondary hypothyroidism

    • Primary hypothyroidism, secondary hyperthyroidism

    Correct Answer
    A. Primary hypothyroidism, secondary hypothyroidism
    Explanation
    When the thyroid is destroyed, it is unable to produce enough thyroid hormones, resulting in primary hypothyroidism. This condition is characterized by a decrease in thyroid hormone levels. Damage to the pituitary gland, which controls the thyroid, can lead to secondary hypothyroidism. In this case, the pituitary gland is unable to produce enough thyroid-stimulating hormone (TSH), which is needed to stimulate the thyroid to produce thyroid hormones. This also results in decreased thyroid hormone levels, but the cause is the dysfunction of the pituitary gland rather than the thyroid itself.

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  • 20. 

    The juvenile-onset of hypothyroidism is called Hereditary Hypothyroidism.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Congenital hypothyroidism.

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  • 21. 

    Congenital secondary hypothyroidism is associated with ____.

    • Dwarfism

    • German shepherds

    • 4 year old Priscilla

    • The Mafia (Shame....shame....)

    Correct Answer
    A. Dwarfism
    Explanation
    Congenital secondary hypothyroidism is associated with dwarfism because it is a condition that affects the thyroid gland's ability to produce enough thyroid hormone. This hormone is essential for normal growth and development, and a deficiency can lead to stunted growth and short stature, which is characteristic of dwarfism.

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  • 22. 

    Most common cause of Hypothyroidism in felines is ____.

    • Iatrogenic

    • Congenital

    • Hereditary

    • Rebellious thyroid

    Correct Answer
    A. Iatrogenic
    Explanation
    Iatrogenic refers to a condition or disease that is caused by medical treatment or intervention. In the case of feline hypothyroidism, iatrogenic hypothyroidism occurs as a result of medical treatments such as surgery or radiation therapy that may damage or remove the thyroid gland. This can lead to a decrease in thyroid hormone production and subsequent hypothyroidism in cats.

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  • 23. 

    Select the causes of iatrogenic hypothyroidism in felines (whereby they're being treated for hyperthyroidism).

    • Radioactive iodine treatment

    • Surgical removal of the thyroid gland

    • Use of anti-thyroid drugs

    • Surgical removal of the pituitary gland

    Correct Answer(s)
    A. Radioactive iodine treatment
    A. Surgical removal of the thyroid gland
    A. Use of anti-thyroid drugs
    Explanation
    The causes of iatrogenic hypothyroidism in felines include radioactive iodine treatment, surgical removal of the thyroid gland, and the use of anti-thyroid drugs. Radioactive iodine treatment destroys the overactive thyroid tissue, but it can also damage the healthy thyroid tissue, leading to hypothyroidism. Surgical removal of the thyroid gland eliminates the source of hyperthyroidism but can result in a complete loss of thyroid function. Anti-thyroid drugs are used to suppress the production of thyroid hormones, but if the dosage is too high or prolonged, it can cause hypothyroidism. Surgical removal of the pituitary gland is not a cause of iatrogenic hypothyroidism.

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  • 24. 

    Select the clinical signs of hypothyroidism.

    • Bilaterally symmetrical alopecia (non-pruritic)

    • Pruritic alopecia

    • Dry skin/Excessive shedding/slow hair re-growth

    • Lethargy/exercise intolerance

    • Inappetance

    • Mental dullness

    • Facial paralysis, seizures

    • Hypothermia

    • Hypoglycemia

    • PU/PD

    Correct Answer(s)
    A. Bilaterally symmetrical alopecia (non-pruritic)
    A. Dry skin/Excessive shedding/slow hair re-growth
    A. Lethargy/exercise intolerance
    A. Inappetance
    A. Mental dullness
    A. Facial paralysis, seizures
    A. Hypothermia
    Explanation
    The clinical signs of hypothyroidism include bilaterally symmetrical alopecia (non-pruritic), dry skin/excessive shedding/slow hair re-growth, lethargy/exercise intolerance, inappetance, mental dullness, facial paralysis, seizures, and hypothermia. These signs indicate a decrease in thyroid hormone production, leading to various symptoms such as hair loss, dry skin, low energy levels, decreased appetite, cognitive impairment, facial paralysis, seizures, and low body temperature.

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  • 25. 

    Hypothyroidism is the most over-diagnosed disease in small animal practice. 

    • True

    • False

    Correct Answer
    A. True
    Explanation
    This statement suggests that hypothyroidism is frequently misdiagnosed in small animal practice. This could be due to a variety of factors, such as the similarity of symptoms to other conditions or the reliance on diagnostic tests that may not always be accurate. It is important for veterinarians to carefully consider all possible causes of a pet's symptoms and to use multiple diagnostic tools to confirm a diagnosis of hypothyroidism.

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  • 26. 

    Which type of anemia is likely to be seen in the diagnostic process of hypothyroidism?

    • Normocytic, normochromic, non-regenerative

    • Macrocytic, normochromic, non-regenrative

    • Macrocytic, hypochromic, regenerative

    • The annoying type

    Correct Answer
    A. Normocytic, normochromic, non-regenerative
    Explanation
    Normocytic, normochromic, non-regenerative anemia is likely to be seen in the diagnostic process of hypothyroidism. This type of anemia is characterized by normal-sized red blood cells with normal hemoglobin concentration, but a decreased number of reticulocytes (immature red blood cells) in the blood. In hypothyroidism, the thyroid gland does not produce enough thyroid hormones, which can lead to a decrease in red blood cell production and result in normocytic, normochromic, non-regenerative anemia.

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  • 27. 

    Which values are likely to be increased in patients with hypothyroidism? 

    • AlkPhos, Ck, Triglycerides

    • BUN and Creatinine

    • AlkPhos, ALT, BUN

    • AlkPhos, Ck, ALT

    Correct Answer
    A. AlkPhos, Ck, Triglycerides
    Explanation
    Patients with hypothyroidism often have elevated levels of AlkPhos, Ck, and Triglycerides. AlkPhos is an enzyme found in the liver, bone, and other tissues, and its levels can increase in hypothyroidism due to impaired liver function. Ck is an enzyme found in muscle cells, and its levels can be elevated in hypothyroidism due to muscle damage. Triglycerides, a type of fat in the blood, can also be increased in hypothyroidism due to decreased metabolism and impaired lipid clearance. Therefore, the values of AlkPhos, Ck, and Triglycerides are likely to be increased in patients with hypothyroidism.

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  • 28. 

    The diagnostic value of serum _____ in a patient with hypothyroidism is ____.

    • T3, weak

    • T3, high

    • T3, low

    • T4, weak

    Correct Answer
    A. T3, weak
    Explanation
    In a patient with hypothyroidism, the diagnostic value of serum T3 is weak. This means that the levels of T3 in the patient's blood are low, which is consistent with hypothyroidism. T3 is one of the thyroid hormones that plays a crucial role in regulating metabolism, growth, and development. In hypothyroidism, the thyroid gland does not produce enough thyroid hormones, leading to various symptoms such as fatigue, weight gain, and cold intolerance. Measuring the levels of T3 in the blood can help in diagnosing hypothyroidism, and if the levels are weak or low, it indicates an underactive thyroid gland.

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  • 29. 

    In dogs with hypothyroidism, you will observe _____ T4. This result can also be seen with other disorders. 

    • Low resting

    • High resting

    • Weak resting

    • Absence of

    Correct Answer
    A. Low resting
    Explanation
    In dogs with hypothyroidism, the levels of T4 hormone are typically low when measured at rest. This is because hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormones, including T4. This can lead to various symptoms and health issues in dogs. It is important to note that low resting T4 levels can also be observed in other disorders, so additional diagnostic tests may be necessary to confirm the presence of hypothyroidism.

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  • 30. 

    The best test for hypothyroidism is ____.

    • TSH stimulation

    • TRH stimulation

    • Serum T3

    • Serum T4

    Correct Answer
    A. TSH stimulation
    Explanation
    TSH stimulation is the best test for hypothyroidism because it measures the level of thyroid-stimulating hormone (TSH) in the blood. TSH is produced by the pituitary gland and stimulates the thyroid gland to produce and release thyroid hormones. In hypothyroidism, the thyroid gland does not produce enough thyroid hormones, causing an increase in TSH levels as the pituitary gland tries to stimulate the thyroid. Therefore, measuring TSH levels after stimulation can accurately diagnose hypothyroidism. Serum T3 and T4 levels can also be measured, but TSH stimulation is considered the most reliable test for hypothyroidism.

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  • 31. 

    Primary hypothyroidism T4 is normal.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Below normal.

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  • 32. 

    For normal results, T4 should increase by at least _____ over the normal range.

    • 2 mg/dL

    • 3 mg/dL

    • 2 mL/Kg

    • 3 mL/Kg

    Correct Answer
    A. 2 mg/dL
    Explanation
    T4 refers to the thyroid hormone thyroxine, which plays a crucial role in regulating metabolism. The normal range for T4 levels is typically between 4.5 to 11.2 micrograms per deciliter (μg/dL). In order to maintain normal results, T4 should increase by at least 2 mg/dL over the normal range. This suggests that an increase in T4 levels within this range is necessary for maintaining a healthy metabolism and overall thyroid function.

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    Quiz Edited by
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