Cytology: Thyroid And Hypothyroidism

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1. What are T3 and T4?

Explanation

I hope you did your taxes before finals.

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About This Quiz
Cytology: Thyroid And Hypothyroidism - Quiz

This quiz on 'Cytology: Thyroid and Hypothyroidism' explores the anatomy and function of the thyroid gland, including its hormone production and impact on metabolism. It assesses understanding of... see morehypothyroidism, particularly its prevalence in dogs, enhancing both academic knowledge and practical insight. see less

2. _______ is the increase in thyroid hormone production, which leads to ______ rate of metabolism.

Explanation

Hyperthyroidism is a condition characterized by excessive production of thyroid hormones by the thyroid gland. These hormones play a crucial role in regulating metabolism. When there is an increase in thyroid hormone production, it leads to an increased rate of metabolism. This means that the body's processes, such as digestion and energy expenditure, speed up. Therefore, the correct answer is Hyperthyroidism, increased.

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3. Congenital secondary hypothyroidism is associated with ____.

Explanation

Congenital secondary hypothyroidism is associated with dwarfism because it is a condition that affects the thyroid gland's ability to produce enough thyroid hormone. This hormone is essential for normal growth and development, and a deficiency can lead to stunted growth and short stature, which is characteristic of dwarfism.

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4. T3 and T4 regulate the rate of metabolism of....

Explanation

T3 and T4 are hormones produced by the thyroid gland that play a crucial role in regulating metabolism. These hormones are responsible for controlling the rate at which the body breaks down and utilizes proteins, carbohydrates, and fats for energy. Therefore, the correct answer is "Protein, carbohydrates, and fats" as T3 and T4 regulate the metabolism of all three macronutrients.

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5. _______ is the decrease of thyroid hormone production, which leads to  ______ rate of metabolism. 

Explanation

Hypothyroidism is a condition characterized by a decrease in thyroid hormone production. Thyroid hormones play a crucial role in regulating metabolism, so a decrease in their production would result in a decreased rate of metabolism.

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6. Hypothyroidism is the most over-diagnosed disease in small animal practice. 

Explanation

This statement suggests that hypothyroidism is frequently misdiagnosed in small animal practice. This could be due to a variety of factors, such as the similarity of symptoms to other conditions or the reliance on diagnostic tests that may not always be accurate. It is important for veterinarians to carefully consider all possible causes of a pet's symptoms and to use multiple diagnostic tools to confirm a diagnosis of hypothyroidism.

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7. TSH stimulates _______ synthesis and secretion.

Explanation

TSH (thyroid-stimulating hormone) stimulates the synthesis and secretion of thyroid hormone. Thyroid hormone is produced by the thyroid gland and plays a crucial role in regulating metabolism, growth, and development in the body. TSH acts on the thyroid gland to promote the production and release of thyroid hormone, which then acts on various tissues and organs to maintain proper functioning.

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8. Primary hypothyroidism T4 is normal.

Explanation

Below normal.

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9. Destruction of the thyroid causes ________, while damage to the pituitary tumor could lead to _______.

Explanation

When the thyroid is destroyed, it is unable to produce enough thyroid hormones, resulting in primary hypothyroidism. This condition is characterized by a decrease in thyroid hormone levels. Damage to the pituitary gland, which controls the thyroid, can lead to secondary hypothyroidism. In this case, the pituitary gland is unable to produce enough thyroid-stimulating hormone (TSH), which is needed to stimulate the thyroid to produce thyroid hormones. This also results in decreased thyroid hormone levels, but the cause is the dysfunction of the pituitary gland rather than the thyroid itself.

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10. The _____ system is a coordinated response of the ________.

Explanation

The correct answer is Negative feedback, hypothalmic-pituitary-thyroid axis. This is because negative feedback is a regulatory mechanism in which the output of a system inhibits or reverses the original stimulus, maintaining homeostasis. The hypothalmic-pituitary-thyroid axis is a hormonal pathway that regulates the production and release of thyroid hormones, which play a crucial role in metabolism and growth. Together, negative feedback and the hypothalmic-pituitary-thyroid axis work in coordination to maintain the balance of thyroid hormone levels in the body.

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11. Select the correct statement about Thyroid gland anatomy.

Explanation

The correct statement about Thyroid gland anatomy is that it is bilobed, caudal to the larynx, and adjacent to the trachea.

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12. 95% of Hypothyroidism are due to ____.

Explanation

Hypothyroidism is a condition characterized by an underactive thyroid gland, leading to a decrease in the production of thyroid hormones. The most common cause of hypothyroidism is the destruction of the thyroid gland. This can occur due to various reasons such as autoimmune diseases like Hashimoto's thyroiditis, where the immune system mistakenly attacks and damages the thyroid gland. Other causes include radiation therapy, surgical removal of the thyroid gland, or certain medications. Destruction of the thyroid gland accounts for approximately 95% of cases of hypothyroidism.

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13. Calcitonin ________ bone formation and _______ bone breakdown. This decreases the level of Calcium in the bloodstream.

Explanation

Calcitonin is a hormone that regulates calcium levels in the bloodstream. It works by increasing bone formation, which means that it promotes the deposition of calcium into the bones. At the same time, calcitonin inhibits bone breakdown, which prevents the release of calcium from the bones into the bloodstream. By increasing bone formation and decreasing bone breakdown, calcitonin helps to decrease the level of calcium in the bloodstream.

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14. Which type of anemia is likely to be seen in the diagnostic process of hypothyroidism?

Explanation

Normocytic, normochromic, non-regenerative anemia is likely to be seen in the diagnostic process of hypothyroidism. This type of anemia is characterized by normal-sized red blood cells with normal hemoglobin concentration, but a decreased number of reticulocytes (immature red blood cells) in the blood. In hypothyroidism, the thyroid gland does not produce enough thyroid hormones, which can lead to a decrease in red blood cell production and result in normocytic, normochromic, non-regenerative anemia.

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15. Hyperthyroidism is most common in _____.

Explanation

Ever heard of Red Planet disease? No? Maybe you should visit Mars and be more educated.

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16. The best test for hypothyroidism is ____.

Explanation

TSH stimulation is the best test for hypothyroidism because it measures the level of thyroid-stimulating hormone (TSH) in the blood. TSH is produced by the pituitary gland and stimulates the thyroid gland to produce and release thyroid hormones. In hypothyroidism, the thyroid gland does not produce enough thyroid hormones, causing an increase in TSH levels as the pituitary gland tries to stimulate the thyroid. Therefore, measuring TSH levels after stimulation can accurately diagnose hypothyroidism. Serum T3 and T4 levels can also be measured, but TSH stimulation is considered the most reliable test for hypothyroidism.

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17. What is the function of Calcitonin?

Explanation

Calcitonin is a hormone secreted by the thyroid gland that plays a crucial role in maintaining blood calcium levels. It helps to regulate calcium levels by inhibiting the release of calcium from bones into the bloodstream and promoting the excretion of calcium by the kidneys. This hormone works in opposition to parathyroid hormone, which increases blood calcium levels. By maintaining blood calcium levels within a narrow range, calcitonin ensures proper functioning of various physiological processes, including nerve transmission, muscle contraction, and bone health.

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18. Hypothyroidism is most common in ____.

Explanation

It's called Smaug's disease in dragons. In case you were wondering. You win bonus points if you get the reference.

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19. Select the correct statement about the negative feedback system.

Explanation

The correct statement about the negative feedback system is that TRH is released, which then stimulates the release of TSH. TSH in turn stimulates the secretion of T3/T4 hormones. Finally, T3/T4 hormones inhibit the release of TRH. This negative feedback loop helps regulate the levels of T3/T4 hormones in the body, maintaining homeostasis.

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20. TRH stands for...

Explanation

The correct answer is Thyrotropin-Releasing Hormone. This hormone is responsible for stimulating the release of thyroid-stimulating hormone (TSH) from the pituitary gland. TSH then acts on the thyroid gland to promote the production and release of thyroid hormones, which play a crucial role in regulating metabolism and growth.

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21. Most common cause of Hypothyroidism in felines is ____.

Explanation

Iatrogenic refers to a condition or disease that is caused by medical treatment or intervention. In the case of feline hypothyroidism, iatrogenic hypothyroidism occurs as a result of medical treatments such as surgery or radiation therapy that may damage or remove the thyroid gland. This can lead to a decrease in thyroid hormone production and subsequent hypothyroidism in cats.

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22. For normal results, T4 should increase by at least _____ over the normal range.

Explanation

T4 refers to the thyroid hormone thyroxine, which plays a crucial role in regulating metabolism. The normal range for T4 levels is typically between 4.5 to 11.2 micrograms per deciliter (μg/dL). In order to maintain normal results, T4 should increase by at least 2 mg/dL over the normal range. This suggests that an increase in T4 levels within this range is necessary for maintaining a healthy metabolism and overall thyroid function.

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23. The term "Thyroid nodule" is used to describe......

Explanation

The term "Thyroid nodule" is used to describe an enlarged thyroid gland. Thyroid nodules are abnormal growths or lumps that form in the thyroid gland, which is located in the front of the neck. These nodules can be solid or fluid-filled and are usually benign, although some may be cancerous. The enlargement of the thyroid gland can cause various symptoms such as difficulty swallowing, hoarseness, or a visible lump in the neck. It is important to evaluate and monitor thyroid nodules to determine if any further treatment or intervention is necessary.

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24. Why do thyroid hormones do to TRH?

Explanation

That one time when TRH trolled the optic nerve so hard he basically rage quit....(TRH was grounded for 3 months)

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25. Select the causes of iatrogenic hypothyroidism in felines (whereby they're being treated for hyperthyroidism).

Explanation

The causes of iatrogenic hypothyroidism in felines include radioactive iodine treatment, surgical removal of the thyroid gland, and the use of anti-thyroid drugs. Radioactive iodine treatment destroys the overactive thyroid tissue, but it can also damage the healthy thyroid tissue, leading to hypothyroidism. Surgical removal of the thyroid gland eliminates the source of hyperthyroidism but can result in a complete loss of thyroid function. Anti-thyroid drugs are used to suppress the production of thyroid hormones, but if the dosage is too high or prolonged, it can cause hypothyroidism. Surgical removal of the pituitary gland is not a cause of iatrogenic hypothyroidism.

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26. Which values are likely to be increased in patients with hypothyroidism? 

Explanation

Patients with hypothyroidism often have elevated levels of AlkPhos, Ck, and Triglycerides. AlkPhos is an enzyme found in the liver, bone, and other tissues, and its levels can increase in hypothyroidism due to impaired liver function. Ck is an enzyme found in muscle cells, and its levels can be elevated in hypothyroidism due to muscle damage. Triglycerides, a type of fat in the blood, can also be increased in hypothyroidism due to decreased metabolism and impaired lipid clearance. Therefore, the values of AlkPhos, Ck, and Triglycerides are likely to be increased in patients with hypothyroidism.

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27. In dogs with hypothyroidism, you will observe _____ T4. This result can also be seen with other disorders. 

Explanation

In dogs with hypothyroidism, the levels of T4 hormone are typically low when measured at rest. This is because hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormones, including T4. This can lead to various symptoms and health issues in dogs. It is important to note that low resting T4 levels can also be observed in other disorders, so additional diagnostic tests may be necessary to confirm the presence of hypothyroidism.

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28. Lymphoctic thyroidis and idiopathic atrophy of the thyroid gland lead to ____.

Explanation

Lymphocytic thyroiditis and idiopathic atrophy of the thyroid gland are both conditions that can cause damage to the thyroid gland. This damage can result in a decrease in the production of thyroid hormones, leading to hypothyroidism. Hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormones to meet the body's needs. This can result in symptoms such as fatigue, weight gain, and cold intolerance. Therefore, it is logical to conclude that lymphocytic thyroiditis and idiopathic atrophy of the thyroid gland can lead to hypothyroidism.

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29. TRH binds to cells in the _______ which stimulate the release of _____.

Explanation

Because there are lots of cells in a prison.

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30. The juvenile-onset of hypothyroidism is called Hereditary Hypothyroidism.

Explanation

Congenital hypothyroidism.

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31. The diagnostic value of serum _____ in a patient with hypothyroidism is ____.

Explanation

In a patient with hypothyroidism, the diagnostic value of serum T3 is weak. This means that the levels of T3 in the patient's blood are low, which is consistent with hypothyroidism. T3 is one of the thyroid hormones that plays a crucial role in regulating metabolism, growth, and development. In hypothyroidism, the thyroid gland does not produce enough thyroid hormones, leading to various symptoms such as fatigue, weight gain, and cold intolerance. Measuring the levels of T3 in the blood can help in diagnosing hypothyroidism, and if the levels are weak or low, it indicates an underactive thyroid gland.

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32. Select the clinical signs of hypothyroidism.

Explanation

The clinical signs of hypothyroidism include bilaterally symmetrical alopecia (non-pruritic), dry skin/excessive shedding/slow hair re-growth, lethargy/exercise intolerance, inappetance, mental dullness, facial paralysis, seizures, and hypothermia. These signs indicate a decrease in thyroid hormone production, leading to various symptoms such as hair loss, dry skin, low energy levels, decreased appetite, cognitive impairment, facial paralysis, seizures, and low body temperature.

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What are T3 and T4?
_______ is the increase in thyroid hormone production, which leads to...
Congenital secondary hypothyroidism is associated with ____.
T3 and T4 regulate the rate of metabolism of....
_______ is the decrease of thyroid hormone production, which leads to...
Hypothyroidism is the most over-diagnosed disease in small animal...
TSH stimulates _______ synthesis and secretion.
Primary hypothyroidism T4 is normal.
Destruction of the thyroid causes ________, while damage to the...
The _____ system is a coordinated response of the ________.
Select the correct statement about Thyroid gland anatomy.
95% of Hypothyroidism are due to ____.
Calcitonin ________ bone formation and _______ bone breakdown. This...
Which type of anemia is likely to be seen in the diagnostic process of...
Hyperthyroidism is most common in _____.
The best test for hypothyroidism is ____.
What is the function of Calcitonin?
Hypothyroidism is most common in ____.
Select the correct statement about the negative feedback system.
TRH stands for...
Most common cause of Hypothyroidism in felines is ____.
For normal results, T4 should increase by at least _____ over the...
The term "Thyroid nodule" is used to describe......
Why do thyroid hormones do to TRH?
Select the causes of iatrogenic hypothyroidism in felines (whereby...
Which values are likely to be increased in patients with...
In dogs with hypothyroidism, you will observe _____ T4. This result...
Lymphoctic thyroidis and idiopathic atrophy of the thyroid gland lead...
TRH binds to cells in the _______ which stimulate the release of...
The juvenile-onset of hypothyroidism is called Hereditary...
The diagnostic value of serum _____ in a patient with hypothyroidism...
Select the clinical signs of hypothyroidism.
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