Cancer Drugs
Based on Dr. Wellstein's lecture, all questions are multiple-multiple choice.
- 1.
The most deadly of the following forms of cancer today for both men and women is
- A.
Breast/prostate
- B.
Lung/bronchus
- C.
Stomach
- D.
Colon/rectal
Correct Answer
B. Lung/bronchus -
- 2.
Pancreatic cancer is
- A.
Very lethal
- B.
About 50-50
- C.
Not that lethal
Correct Answer
A. Very lethal -
- 3.
Giving chemotherapy post-masectomy
- A.
Helps even at low doses
- B.
Helps only at the full dose
- C.
Doesn't help even at high doses
Correct Answer
B. Helps only at the full dose -
- 4.
Tumors are
- A.
Heterogeneous
- B.
Homogeneous
Correct Answer
A. Heterogeneous -
- 5.
Side effects of cytotoxic drugs include
- A.
Ulcers
- B.
Hair loss
- C.
Poor wound healing
- D.
Leukemia
- E.
Increased spermatogenesis
Correct Answer(s)
A. Ulcers
B. Hair loss
C. Poor wound healing
D. Leukemia -
- 6.
Vincristine _____ microtubule formation, unlike paclitaxel.
- A.
Enhances
- B.
Inhibits
Correct Answer
B. Inhibits -
- 7.
Poison gases and derivatives may be given at low doses because they prevent bone marrow proliferation via
- A.
Crosslinking DNA
- B.
Monoalkylating DNA
- C.
Binding to DNA
- D.
Crosslinking RNA
Correct Answer(s)
A. Crosslinking DNA
C. Binding to DNA -
- 8.
Cyclophosphamide is a prodrug.
- A.
True
- B.
False
Correct Answer
A. True -
- 9.
5FU allows __ to turn into ___
- A.
A, G
- B.
T, U
- C.
U, T
- D.
C, A
Correct Answer
C. U, T -
- 10.
The following are DHFR inhibitors
- A.
MTX
- B.
Trimethoprim
- C.
Thioguanine
- D.
Mercaptopurine
- E.
Pyrimethamine
Correct Answer(s)
A. MTX
B. Trimethoprim
E. Pyrimethamine -
- 11.
Azathioprine is an immunosuppressant
- A.
True
- B.
False
Correct Answer
A. True -
- 12.
Topoisomerase inhibitors include
- A.
Doxorubicin
- B.
Adriamycin
- C.
Anthracycline
- D.
Bevacizumab
- E.
Trastuzumab
Correct Answer(s)
A. Doxorubicin
B. Adriamycin
C. Anthracycline -
- 13.
Doxorubicin and Vinblastine lead to cardio problems
- A.
True
- B.
False
Correct Answer
B. False -
- 14.
Multigene assays can predict who needs chemo post-surgically and who doesn't
- A.
True
- B.
False
Correct Answer
A. True -
- 15.
Antibodies are
- A.
Big
- B.
Small
Correct Answer
A. Big -
- 16.
Kinase inhibitors are
- A.
High specificity
- B.
Low specificity
- C.
Cheap
- D.
Expensive
Correct Answer(s)
B. Low specificity
C. Cheap -
- 17.
Antibodies are like the grim reaper
- A.
True
- B.
False
Correct Answer
A. True -
- 18.
HER2 inhibitor, Trastuzumab, can treat lung cancer
- A.
True
- B.
False
Correct Answer
A. True -
- 19.
Long term HER2 inhibitor treatment is dangerous because of
- A.
Infertility
- B.
Heart failure
- C.
High blood pressure
- D.
Hair loss
Correct Answer
B. Heart failure -
- 20.
Mutations on the EGFreceptor are associated with drug ____
- A.
Sensitivity
- B.
Resistance
Correct Answer(s)
A. Sensitivity
B. Resistance -
- 21.
The most specific kinase inhibitor is
- A.
Lapatinib
- B.
Imatinib
- C.
Sorafenib
- D.
Gefitinib
- E.
Erlotinib
Correct Answer
A. Lapatinib -
- 22.
T790M
- A.
Enhances cancer drug action
- B.
Inhibits cancer drug action
Correct Answer
B. Inhibits cancer drug action -
- 23.
You are on an EGF inhibitor. Do you want the rash? (assuming you want to live)
- A.
Yes
- B.
No
Correct Answer
A. Yes -
- 24.
Cancer recruits HIF to turn on genes that act to
- A.
Kill blood vessels
- B.
Create blood vessels
Correct Answer
B. Create blood vessels -
- 25.
Blocking VEGF can increase life expectancy by at least a year
- A.
True
- B.
False
Correct Answer
B. False -
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Current Version
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Dec 26, 2012Quiz Edited by
ProProfs Editorial Team -
Mar 17, 2009Quiz Created by
Icanhasfarm
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