Cancer Drugs

1. Azathioprine is an immunosuppressant

True

False

2. Vincristine _____ microtubule formation, unlike paclitaxel.

Enhances

Inhibits

3. Tumors are

Heterogeneous

Homogeneous

4. Cyclophosphamide is a prodrug.

True

False

5. Multigene assays can predict who needs chemo post-surgically and who doesn't

True

False

6. Pancreatic cancer is

Very lethal

About 50-50

Not that lethal

7. Antibodies are like the grim reaper

True

False

8. You are on an EGF inhibitor. Do you want the rash? (assuming you want to live)

Yes

No

9. The most deadly of the following forms of cancer today for both men and women is

Breast/prostate

Lung/bronchus

Stomach

Colon/rectal

10. Long term HER2 inhibitor treatment is dangerous because of

Infertility

Heart failure

High blood pressure

Hair loss

11. HER2 inhibitor, Trastuzumab, can treat lung cancer

True

False

12. Cancer recruits HIF to turn on genes that act to

Kill blood vessels

Create blood vessels

13. T790M

Enhances cancer drug action

Inhibits cancer drug action

14. Antibodies are

Big

Small

15. 5FU allows to turn into _

A, G

T, U

U, T

C, A

16. Giving chemotherapy post-masectomy

Helps even at low doses

Helps only at the full dose

Doesn't help even at high doses

17. Side effects of cytotoxic drugs include

Ulcers

Hair loss

Poor wound healing

Leukemia

Increased spermatogenesis

Submit

18. Doxorubicin and Vinblastine lead to cardio problems

True

False

19. Topoisomerase inhibitors include

Doxorubicin

Adriamycin

Anthracycline

Bevacizumab

Trastuzumab

Submit

20. The most specific kinase inhibitor is

Lapatinib

Imatinib

Sorafenib

Gefitinib

Erlotinib

21. Blocking VEGF can increase life expectancy by at least a year

True

False

22. Kinase inhibitors are

High specificity

Low specificity

Cheap

Expensive

Submit

23. Poison gases and derivatives may be given at low doses because they prevent bone marrow proliferation via

Crosslinking DNA

Monoalkylating DNA

Binding to DNA

Crosslinking RNA

Submit

24. The following are DHFR inhibitors

MTX

Trimethoprim

Thioguanine

Mercaptopurine

Pyrimethamine

Submit

25. Mutations on the EGFreceptor are associated with drug ____

Sensitivity

Resistance

Submit

Cancer Drugs

1. Azathioprine is an immunosuppressant

2.

What first name or nickname would you like us to use?

2. Vincristine _____ microtubule formation, unlike paclitaxel.

3. Tumors are

4. Cyclophosphamide is a prodrug.

5. Multigene assays can predict who needs chemo post-surgically and who doesn't

6. Pancreatic cancer is

7. Antibodies are like the grim reaper

8. You are on an EGF inhibitor. Do you want the rash? (assuming you want to live)

9. The most deadly of the following forms of cancer today for both men and women is

10. Long term HER2 inhibitor treatment is dangerous because of

11. HER2 inhibitor, Trastuzumab, can treat lung cancer

12. Cancer recruits HIF to turn on genes that act to

13. T790M

14. Antibodies are

15. 5FU allows __ to turn into ___

16. Giving chemotherapy post-masectomy

17. Side effects of cytotoxic drugs include

18. Doxorubicin and Vinblastine lead to cardio problems

19. Topoisomerase inhibitors include

20. The most specific kinase inhibitor is

21. Blocking VEGF can increase life expectancy by at least a year

22. Kinase inhibitors are

23. Poison gases and derivatives may be given at low doses because they prevent bone marrow proliferation via

24. The following are DHFR inhibitors

25. Mutations on the EGFreceptor are associated with drug ____

15. 5FU allows to turn into _