Block 9 Micro Mhc Antigen Presentation

12 Questions | By Chachelly | Last updated: Feb 19, 2013 | Total Attempts: 198

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1.

To what type of pathogen are patients with bare lymphocyte syndrome most likely to be vulnerable?
- A.
  
  Viruses
- B.
  
  Intracellular bacteria
- C.
  
  Extracellular protozoans
- D.
  
  Extracellular bacteria
- E.
  
  Intracellular protozoans
- F.
  
  All of the Above
2.

To what type of pathogen are patients with HLA class I deficiency (bare lymphocyte syndrome type I) most likely to be vulnerable?
- A.
  
  Viruses
- B.
  
  Intracellular bacteria
- C.
  
  Extracellular protozoans
- D.
  
  Extracellular bacteria
- E.
  
  Intracellular protozoans
- F.
  
  None of the Above
3.

What is the minimum number of different MHC-I alleles that can be present on the cell surface of a normal, healthy, individuals?
- A.
  
  1
- B.
  
  2
- C.
  
  3
- D.
  
  4
- E.
  
  5
- F.
  
  6
4.

What is the maximum number of different MHC-I alleles that can be present on the cell surface of a normal, healthy, individuals?
- A.
  
  1
- B.
  
  2
- C.
  
  3
- D.
  
  4
- E.
  
  5
- F.
  
  6
5.

Which cell is the target of MHC-I-restricted antigen presentation?
- A.
  
  B lymphocyte
- B.
  
  Macrophage
- C.
  
  CD4 T lymphocyte
- D.
  
  Dendritic cell
- E.
  
  CD8 T lymphocyte
6.

Which cell is the target of MHC-II-restricted antigen presentation?
- A.
  
  B lymphocyte
- B.
  
  Macrophage
- C.
  
  CD4 T lymphocyte
- D.
  
  Dendritic cell
- E.
  
  CD8 T lymphocyte
7.

What is(are) the antigen presenting cell(s) involved in MHC-II-restricted antigen presentation?
- A.
  
  B lymphocyte
- B.
  
  Macrophage
- C.
  
  CD4 T lymphocyte
- D.
  
  Dendritic cell
- E.
  
  CD8 T lymphocyte
8.

What is(are) the antigen presenting cell(s) involved in MHC-I-restricted antigen presentation?
- A.
  
  B lymphocyte
- B.
  
  Macrophage
- C.
  
  CD4 T lymphocyte
- D.
  
  Dendritic cell
- E.
  
  CD8 T lymphocyte
9.

What is the source of peptides involved in MHC-II-restricted antigen presentation?
- A.
  
  Proteasome
- B.
  
  Phagolysosome
- C.
  
  Golgi
- D.
  
  Peptidase
- E.
  
  Nuclease
10.

What is the source of peptides involved in MHC-I-restricted antigen presentation?
- A.
  
  Proteasome
- B.
  
  Phagolysosome
- C.
  
  Golgi
- D.
  
  Peptidase
- E.
  
  Nuclease
11.

Activation of CD8 T lymphocytes requires which elements?
- A.
  
  MHC class I antigen presentation, CD86 co-stimulation and IL-12
- B.
  
  MHC class II antigen presentation, CD86 co-stimulation and IL-12
- C.
  
  MHC class I antigen presentation, CD86 co-stimulation and IL-4
- D.
  
  MHC class II antigen presentation, CD86 co-stimulation and IL-4
- E.
  
  MHC class I antigen presentation, CD40 co-stimulation and IL-12
- F.
  
  MHC class II antigen presentation, CD40 co-stimulation and IL-12
- G.
  
  MHC class I antigen presentation, CD40 co-stimulation and IL-4
- H.
  
  MHC class II antigen presentation, CD40 co-stimulation and IL-4
12.

Activation of CD4 T lymphocytes requires which elements?
- A.
  
  MHC class I antigen presentation, CD86 co-stimulation and IL-12
- B.
  
  MHC class II antigen presentation, CD86 co-stimulation and IL-12
- C.
  
  MHC class I antigen presentation, CD86 co-stimulation and IL-4
- D.
  
  MHC class II antigen presentation, CD86 co-stimulation and IL-4
- E.
  
  MHC class I antigen presentation, CD40 co-stimulation and IL-12
- F.
  
  MHC class II antigen presentation, CD40 co-stimulation and IL-12
- G.
  
  MHC class I antigen presentation, CD40 co-stimulation and IL-4
- H.
  
  MHC class II antigen presentation, CD40 co-stimulation and IL-4