1.
With an infection at the tip of the tongue, which lymph node is most likely to be initially
enlarged and tender?
A. 
B. 
C. 
D. 
E. 
2.
A 30-year old lady visited her dentist for the severe pain around the last lower molar
tooth. The dentist examined and decided to extract the last lower tooth. Two weeks after
the extraction, the lady complained of the loss of taste and general sensation over anterior
two-thirds of the tongue. Which of the following structures was most likely damaged during
the extraction?
A. 
B. 
C. 
D. 
E. 
3.
After protraction of the mandible, it is retracted by which of the following muscles fibers?
A. 
B. 
Anterior fibers of the temporalis muscle
C. 
Middle fibers of the temporalis
D. 
Posterior fibers of the temporalis
E. 
Lateral pterygoid muscle.
4.
Picture 1 shows a Lashley cup used for collecting saliva from the parotid gland. Picture 2
shows that the Lashley cup is placed over the opening of Stensen's duct to collect the saliva
for saliva sample testing. Which of the following is the most ideal site for placing the cup?
A. 
Opposite the first maxillary molar
B. 
Opposite the second mandibular molar
C. 
Opposite the third mandibular molar
D. 
Opposite the second maxillary molar
E. 
Opposite the third maxillary molar
5.
An 11-year-old boy who was hit in the chin by a baseball, is brought to the clinic with
complaints of a sore chin and an inability to taste ice-cream. Which of the following nerves
is most likely injured in this patient?
A. 
B. 
C. 
D. 
E. 
6.
A 20-yr-old girl visits her family physician complaining of difficulty swallowing. The
physician thinks that she has xerostomia, and starts examining the opening of the _____
gland in the oral vestibule.
A. 
B. 
C. 
D. 
E. 
7.
A patient presents with signs of hypothyroidism. To investigate the matter, you measure
the levels of T4 and TSH. If the patient suffers from iodine deficiency, you can expect the
following results:
A. 
B. 
C. 
T4 elevated, TSH elevated
D. 
E. 
8.
The above structure is
A. 
B. 
C. 
D. 
E. 
9.
An elderly patient who takes aspirin for chronic arthritis complains about frequent pain in
the stomach that can be relieved only by eating. One possible solution to the patient’s
problem is to
A. 
Raise the aspirin dose to reduce the stomach pain
B. 
Switch to a drug that has higher potency on COX-1 relative to COX-2
C. 
Use a selective inhibitor of prostaglandin E synthesis
D. 
Use aspirin in combination with a converting enzyme inhibitor
E. 
Switch to a drug that has higher potency on COX-2 relative to COX-1
10.
During the synthesis of steroid hormones, side chain cleavage reactions occur in two
biotransformations. These are:
A. 
Glucocorticoids --> mineralocorticoids and progestins -->androgens
B. 
Progestins --> corticosteroids and androgens -->estrogens
C. 
Cholesterol --> progestins and estrogens --> androgens
D. 
Cholesterol --> progestins and progestins --> androgens
E. 
Androgens --> corticosteroids and androgens --> estrogens
11.
Thromboxane is formed in platelets, where it promotes platelet activation. The formation
of thromboxane can be suppressed by inhibitors of:
A. 
B. 
C. 
D. 
E. 
12.
For a “classical” radioimmunoassay of insulin, you need
A. 
Radiolabeled insulin receptor
B. 
Radioactive insulin in the test tube
C. 
Injection of radioactive insulin in the patient
D. 
E. 
Two-dimensional electrophoresis
13.
The antihypertensive drug captopril acts as an inhibitor of angiotensin converting
enzyme. In addition to reducing the formation of angiotensin II, captopril will also reduce
the level of circulating
A. 
B. 
C. 
D. 
E. 
14.
The nurse notices that a newborn girl has an unusually enlarged clitoris, and asks you
whether this might be a disorder of sexual development. You notice that in addition to the
large clitoris the labia are partially fused. Some tests are done. The hospital lab reports
normal values for serum sodium, potassium and ACTH. An ultrasound scan shows normalsized
adrenal glands. A buccal smear is sex chromatin negative (no Barr body). If this child
has an enzyme deficiency, the missing enzyme is most likely
A. 
B. 
C. 
D. 
E. 
15.
After several attacks of autoimmune thyroiditis, Mrs. O. has developed signs of
hypothyroidism. Her hormone measurements will most likely show:
A. 
B. 
C. 
D. 
E. 
16.
The hydroxylation reactions of steroid hormones in the endocrine glands require
cytochrome P450, NADPH and
A. 
B. 
Pyridoxal phosphate (vitamin B6)
C. 
D. 
E. 
17.
Insulin is synthesized from a larger precursor protein. The following events occur during
insulin synthesis: (1) Formation of disulfide bonds; (2) Secretion by exocytosis; (3)
Removal of the signal sequence; (4) Removal of the C-peptide. In which sequence are these
events most likely to occur?
A. 
B. 
C. 
D. 
E. 
18.
Selective COX-2 inhibitors have been developed, but they should be used with caution
because they can increase the risk of
A. 
B. 
C. 
D. 
Acute myocardial infarction
E. 
19.
Low doses of aspirin are used to reduce the risk of acute myocardial infarction. Which
enzyme is targeted when aspirin is used for this purpose?
A. 
B. 
C. 
D. 
E.