Explore the role of oncoviruses in cell transformation through this focused quiz. Assess key mechanisms like the activation of signaling molecules, alterations in cell cycle control, and the impact of viral proteins on host cell genomes. Essential for students and professionals in virology and oncology.
Virally-encoded proteins that mimic signalling molecules can contribute to cell transformation
Virally-encoded functional cyclin homologs can contribute to cell transformation
Virally-encoded proteins that inactivate cyclin-dependent kinase inhibitors can contribute to cell transformation.
Virally-encoded proteins that activate cyclin-dependent kinase inhibitors can contribute to cell transformation
Virally-encoded proteins that maintain signalling molecules in an activated state can contribute to cell transformation
Creating a hotspot for v-Src integration near a c-oncogene, thereby increasing cell growth and proliferation
Permanently activating the Pkr pathway involved in cell growth and proliferation
Binding protein E7 to Rb and bypassing cell cycle control
Permanently activating the p53 pathway involved in cell growth and proliferation
Permanently activating cell signalling pathways involved in cell growth and proliferation
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Adenoviruses
Hepadnaviruses (Hepatitis B Virus)
Papillomaviruses
Herpesviruses
Retroviruses
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Activating the mitogen activated protein kinase signaling cascade through PP2A phosphatase inhibition
Targeting the proapoptotic protein p53 for ubiquitin-dependent proteasomal degradation
Uncoupling the retinoblastoma restriction point protein pRb from the E2F family of transcription factors
Complexing with and activating the cyclin D/CDK4 kinase complex
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Adenovirus
Poxvirus
Human T-Leukemia Virus
Kaposi's-associated Herpes Virus
Epstein-Barr virus
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EBNA
Latency
Triggering of the Downey type II cells
Replication and assembly in the nucleus of the cells
Poly B cell expansion
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Naked ds DNA virus causing two different types of inclusions
Enveloped ds DNA virus with no know oncogenic potential
Naked ss positive RNA virus transmitted by the fecal oral route
Enveloped ss negative RNA virus
Naked ss negative virus replicating in the nucleus
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RNA-dependent RNA polymerase
RNA-dependent DNA polymerase
DNA-dependent RNA polymerase
DNA-dependent DNA polymerase
Reverse transcriptase
Accumulations of viral proteins in stained, infected cells
Induced by the action of interferon
Found in non-permissive infections of cells
Viral organelles of respiration
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