B58: Steroid Hormones

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SGU Biochemistry - Fall 2009, Lecture 58: Steroid Hormones
Questions from lecture notes from Dr. Trotz

Questions and Answers

1.

____ stimulates the renal reabsorption of Na+ and excretion of K+ (Trotz Lectures 53-59, p. 48)

Correct Answer
aldosterone
2.

______ results in increased gluconeogenesis, anti-inflammatory action, and protein breakdown. (Trotz Lectures 53-59, p. 48)

Correct Answer
cortisol
3.

Estrogens control the ______ cycle and promote the development of female secondary sex characteristics. (Trotz Lectures 53-59, p. 48)

Correct Answer
menstrual
4.

Progesterone is involved in the _____ phase of the uterus and mammary glands, as well as the nidation and maturation of fertilized ovum. (Trotz Lectures 53-59, p. 48)

Correct Answer
secretory
5.

_________ stimulates spermatogenesis and promotes the development of male secondary sex characteristics. (Trotz Lectures 53-59, p. 48)

Correct Answer
testosterone
6.

Which of the following has 21 carbons? (Trotz Lectures 53-59, p. 49)
- A.
  
  Cholesterol
- B.
  
  Pregnenolone
- C.
  
  DHEA
- D.
  
  Testosterone
Correct Answer
B. Pregnenolone
7.

Which of the following has 19 carbons? (Trotz Lectures 53-59, p. 49)
- A.
  
  Cholesterol
- B.
  
  Pregnenolone
- C.
  
  DHEA
- D.
  
  Cortisol
Correct Answer
C. DHEA
8.

Which of the following has 27 carbons? (Trotz Lectures 53-59, p. 49)
- A.
  
  Cholesterol
- B.
  
  Pregnenolone
- C.
  
  Progesterone
- D.
  
  Cortisol
Correct Answer
A. Cholesterol
9.

Desmolase (also known as cholesterol side chain cleavage enzyme or CYP11A) forms _____ from cholesterol. (Trotz Lectures 53-59, p. 49)

Correct Answer
pregnenolone
10.

The transport of cholesterol into the ______ is the regulatory step of cortisol synthesis. (Hint: organelle) (Trotz Lectures 53-59, p. 50)

Correct Answer
mitochondria
11.

The regulatory step of cortisol synthesis is performed by STAR, or steroidogenic _____ _____ protein. (Trotz Lectures 53-59, p. 50)

Correct Answer
acute regulatory
12.

ACTH stimulates steroid synthesis of the _____ ______. (Trotz Lectures 53-59, p. 51)

Correct Answer
adrenal cortex
13.

Z. glomerulosa releases ______. (Trotz Lectures 53-59, p. 51)

Correct Answer
aldosterone
14.

Cortisol is released from the z. ______ of the adrenal cortex. (Trotz Lectures 53-59, p. 51)

Correct Answer
fasciculata
fasiculata
15.

_______ is the feedback inhibitor for ACTH release. (Trotz Lectures 53-59, p. 51)

Correct Answer
cortisol
16.

Cortisol and ______ lead to induction of PEP carboxykinase. Trotz Lectures 53-59, p. 52

Correct Answer
glucagon
17.

Cortisol is transported in blood about 75% bound to transcortin and 15% to ______. Trotz Lectures 53-59, p. 52

Correct Answer
albumin
18.

Only the _____ cortisol can enter the cells and is physiologically active. Trotz Lectures 53-59, p. 52

Correct Answer
unbound
19.

In areas of inflammation, the binding to transcortin is reduced and the local concentration of free ____ is increased. Trotz Lectures 53-59, p. 52

Correct Answer
cortisol
20.

The weak androgens are changed in fat cells to estradiol and in peripheral tissue to ________. Trotz Lectures 53-59, p. 53

Correct Answer
testosterone

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B58: Steroid Hormones

____ stimulates the renal reabsorption of Na+ and excretion of K+ (Trotz Lectures 53-59, p. 48)

______ results in increased gluconeogenesis, anti-inflammatory action, and protein breakdown. (Trotz Lectures 53-59, p. 48)

Estrogens control the ______ cycle and promote the development of female secondary sex characteristics. (Trotz Lectures 53-59, p. 48)

Progesterone is involved in the _____ phase of the uterus and mammary glands, as well as the nidation and maturation of fertilized ovum. (Trotz Lectures 53-59, p. 48)

_________ stimulates spermatogenesis and promotes the development of male secondary sex characteristics. (Trotz Lectures 53-59, p. 48)

Which of the following has 21 carbons? (Trotz Lectures 53-59, p. 49)

Which of the following has 19 carbons? (Trotz Lectures 53-59, p. 49)

Which of the following has 27 carbons? (Trotz Lectures 53-59, p. 49)

Desmolase (also known as cholesterol side chain cleavage enzyme or CYP11A) forms _____ from cholesterol. (Trotz Lectures 53-59, p. 49)

The transport of cholesterol into the ______ is the regulatory step of cortisol synthesis. (Hint: organelle) (Trotz Lectures 53-59, p. 50)

The regulatory step of cortisol synthesis is performed by STAR, or steroidogenic _ _ protein. (Trotz Lectures 53-59, p. 50)

ACTH stimulates steroid synthesis of the _ __. (Trotz Lectures 53-59, p. 51)

Z. glomerulosa releases ______. (Trotz Lectures 53-59, p. 51)

Cortisol is released from the z. ______ of the adrenal cortex. (Trotz Lectures 53-59, p. 51)

_______ is the feedback inhibitor for ACTH release. (Trotz Lectures 53-59, p. 51)

Cortisol and ______ lead to induction of PEP carboxykinase. Trotz Lectures 53-59, p. 52

Cortisol is transported in blood about 75% bound to transcortin and 15% to ______. Trotz Lectures 53-59, p. 52

Only the _____ cortisol can enter the cells and is physiologically active. Trotz Lectures 53-59, p. 52

In areas of inflammation, the binding to transcortin is reduced and the local concentration of free ____ is increased. Trotz Lectures 53-59, p. 52

The weak androgens are changed in fat cells to estradiol and in peripheral tissue to ________. Trotz Lectures 53-59, p. 53

B58: Steroid Hormones

____ stimulates the renal reabsorption of Na+ and excretion of K+ (Trotz Lectures 53-59, p. 48)

______ results in increased gluconeogenesis, anti-inflammatory action, and protein breakdown. (Trotz Lectures 53-59, p. 48)

Estrogens control the ______ cycle and promote the development of female secondary sex characteristics. (Trotz Lectures 53-59, p. 48)

Progesterone is involved in the _____ phase of the uterus and mammary glands, as well as the nidation and maturation of fertilized ovum. (Trotz Lectures 53-59, p. 48)

_________ stimulates spermatogenesis and promotes the development of male secondary sex characteristics. (Trotz Lectures 53-59, p. 48)

Which of the following has 21 carbons? (Trotz Lectures 53-59, p. 49)

Which of the following has 19 carbons? (Trotz Lectures 53-59, p. 49)

Which of the following has 27 carbons? (Trotz Lectures 53-59, p. 49)

Desmolase (also known as cholesterol side chain cleavage enzyme or CYP11A) forms _____ from cholesterol. (Trotz Lectures 53-59, p. 49)

The transport of cholesterol into the ______ is the regulatory step of cortisol synthesis. (Hint: organelle) (Trotz Lectures 53-59, p. 50)

The regulatory step of cortisol synthesis is performed by STAR, or steroidogenic _____ _____ protein. (Trotz Lectures 53-59, p. 50)

ACTH stimulates steroid synthesis of the _____ ______. (Trotz Lectures 53-59, p. 51)

Z. glomerulosa releases ______. (Trotz Lectures 53-59, p. 51)

Cortisol is released from the z. ______ of the adrenal cortex. (Trotz Lectures 53-59, p. 51)

_______ is the feedback inhibitor for ACTH release. (Trotz Lectures 53-59, p. 51)

Cortisol and ______ lead to induction of PEP carboxykinase. Trotz Lectures 53-59, p. 52

Cortisol is transported in blood about 75% bound to transcortin and 15% to ______. Trotz Lectures 53-59, p. 52

Only the _____ cortisol can enter the cells and is physiologically active. Trotz Lectures 53-59, p. 52

In areas of inflammation, the binding to transcortin is reduced and the local concentration of free ____ is increased. Trotz Lectures 53-59, p. 52

The weak androgens are changed in fat cells to estradiol and in peripheral tissue to ________. Trotz Lectures 53-59, p. 53

The regulatory step of cortisol synthesis is performed by STAR, or steroidogenic _ _ protein. (Trotz Lectures 53-59, p. 50)

ACTH stimulates steroid synthesis of the _ __. (Trotz Lectures 53-59, p. 51)