.
Contract bronchial smooth muscle
Stimulate sensory nerve endings in the skin
Relax gastrointestinal smooth muscle
Stimulate gastric acid secretion
Some histamine H1 receptor antagonist are used in prophylaxis and treatment of motion sickness
Histamine H2 receptor antagonists are potentially useful in treatment of gastric hyper secretory state
Chlorphineramine possesses anti-emetic, sedative and anti-muscarinic activity
Histamine H1 receptor antagonists inhibit the release of histamine
Release of EDRF from vascular endothelium resulting in vasodilatation
Direct action on vascular smooth muscle causing vasodilatation
Bronchoconstriction
Release of catecholamines from adrenal medulla
Aspirin
Procaine
Morphine
Sulfadiazine
Driving motor vehicles
Consuming processed cheese
Strenuous physical exertion
All of the above
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