Cardiac Drug Quiz: Beta-Blockers to ACE Inhibitors

1. Which beta-blocker is cardioselective and commonly used for hypertension and angina?

Propranolol

Metoprolol

Nadolol

Labetalol

2. ACE inhibitors lower blood pressure primarily by inhibiting the conversion of angiotensin I to which substance?

Angiotensin II

Renin

Aldosterone

Bradykinin

3. A patient on lisinopril develops a persistent dry cough. What is the most likely cause?

Accumulation of bradykinin

Direct airway irritation

Hyperkalemia

Fluid overload

4. Which ARB is commonly prescribed and does NOT require dose adjustment in renal impairment?

Losartan

Valsartan

Irbesartan

Candesartan

5. Beta-blockers reduce heart rate and myocardial contractility. Which mechanism explains this effect?

Blockade of alpha-1 receptors

Blockade of beta-1 adrenergic receptors

Inhibition of calcium channels

Suppression of renin release

6. Calcium channel blockers like diltiazem are beneficial in heart failure with which condition?

Systolic dysfunction

Diastolic dysfunction

Low ejection fraction

Acute decompensation

7. A major adverse effect of ACE inhibitors in susceptible patients is angioedema. This occurs in what percentage of users?

0.1–0.2%

1–2%

5–10%

15–20%

8. Which cardiac medication is a direct vasodilator and is often combined with a beta-blocker to prevent reflex tachycardia?

Hydralazine

Minoxidil

Nitroglycerin

Sodium nitroprusside

9. Enalapril is a prodrug that must be converted to its active form. What is the active metabolite?

Enalaprilat

Lisinoprilat

Ramiprilat

Benazeprilat

10. ARBs and ACE inhibitors are contraindicated together because of the risk of severe hyperkalemia and renal dysfunction. True or False?

True

False

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Cardiac Drug Quiz: Beta-Blockers to ACE Inhibitors

1. Which beta-blocker is cardioselective and commonly used for hypertension and angina?

2.

What first name or nickname would you like us to use?

2. ACE inhibitors lower blood pressure primarily by inhibiting the conversion of angiotensin I to which substance?

3. A patient on lisinopril develops a persistent dry cough. What is the most likely cause?

4. Which ARB is commonly prescribed and does NOT require dose adjustment in renal impairment?

5. Beta-blockers reduce heart rate and myocardial contractility. Which mechanism explains this effect?

6. Calcium channel blockers like diltiazem are beneficial in heart failure with which condition?

7. A major adverse effect of ACE inhibitors in susceptible patients is angioedema. This occurs in what percentage of users?

8. Which cardiac medication is a direct vasodilator and is often combined with a beta-blocker to prevent reflex tachycardia?

9. Enalapril is a prodrug that must be converted to its active form. What is the active metabolite?

10. ARBs and ACE inhibitors are contraindicated together because of the risk of severe hyperkalemia and renal dysfunction. True or False?

11. Aldosterone antagonists like spironolactone are used in heart failure to prevent _____ and improve survival.

12. Beta-blockers with intrinsic sympathomimetic activity (ISA) such as pindolol cause less _____ reduction compared to non-ISA agents.

13. The combination of hydralazine and isosorbide dinitrate is particularly beneficial in African American patients with systolic heart failure. This combination works by reducing _____ and improving coronary perfusion.

14. Carvedilol is a non-selective beta-blocker with additional _____ blocking properties, which provides extra vasodilatory benefit.

15. ACE inhibitors are first-line therapy for hypertension in patients with diabetes because they provide renal _____ and reduce proteinuria.